Hernandez Gabriel A, Ghatak Abhijt, Diego Jorge M, Marchena Eduardo De
{"title":"Transplant Renal Artery Stenosis Secondary to De Novo Fibromuscular Dysplasia","authors":"Hernandez Gabriel A, Ghatak Abhijt, Diego Jorge M, Marchena Eduardo De","doi":"10.23937/2378-2951/1410109","DOIUrl":"https://doi.org/10.23937/2378-2951/1410109","url":null,"abstract":"","PeriodicalId":15510,"journal":{"name":"Journal of Clinical Cardiology","volume":"38 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75670193","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Platypnea-Orthodeoxia Syndrome: Positional Reversal of the Interatrial Pressure Gradient Demonstrated by Atrial Septal Motion","authors":"Serio Farris, Serio M Kerala","doi":"10.23937/2378-2951/1410107","DOIUrl":"https://doi.org/10.23937/2378-2951/1410107","url":null,"abstract":"Platypnea-Orthodeoxia Syndrome (POS) is a rare clinical syndrome characterized by dyspnea and hypoxemia while upright that are relieved when the patient is supine. A right to left shunt in combination with several hypothesized hemodynamic or structural factors are needed to develop the syndrome. It is an important source of dyspnea in a small percentage of often-elderly patients. The exact mechanism for the positional increase in the shunt has remained elusive. We present the case of an 85-year-old woman with severe POS. The patient has an atrial septal aneurysm with a Patent Foramen Ovale (PFO). We were able to demonstrate a significant increase in the right to left intra-atrial shunt in the upright position using transesophageal echocardiography and agitated saline study. By analyzing the atrial septal motion, we were also able to provide evidence that the shunt is caused by a reversal in the inter-atrial pressure gradient in the upright position, thus we are able to show for the first time that a reversal of the interatrial pressure gradient can be responsible for the positional shunt.","PeriodicalId":15510,"journal":{"name":"Journal of Clinical Cardiology","volume":"20 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84537819","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Giant Right Atrium or Ebstein Anomaly","authors":"Hacer Kamalı, A. Erdem, C. Erol, A. Akçevin","doi":"10.23937/2378-2951/1410104","DOIUrl":"https://doi.org/10.23937/2378-2951/1410104","url":null,"abstract":"Many acquired and congenital pathologies could cause enlargement of Right Atrium (RA). In rare pathologies we couldn’t find an obvious reason for enlargement of RA. Sometimes it leads to misdiagnosis if we try to explain an unknown pathology with well known pathology. In this article we describe a woman who presented with giant enlargement of the RA misdiagnosed as Ebstein anomaly. Cardiac MRI is highly helpful for differential diagnosis of these kinds of atrial pathologies. Although it is rare, giant RA should be considered in differential diagnosis of huge RA without an obvious cause.","PeriodicalId":15510,"journal":{"name":"Journal of Clinical Cardiology","volume":"9 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2017-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82727061","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Heart Remembers: Anterior T wave inversions in a Patient with Intermittent Left Bundle Branch Block","authors":"J. R. Manne","doi":"10.23937/2378-2951/1410105","DOIUrl":"https://doi.org/10.23937/2378-2951/1410105","url":null,"abstract":"Even though the new onset of T wave inversions on the electrocardiogram is always an alarming finding, but they are not always pathognomonic of myocardial ischemia. Many cardiac and non-cardiac conditions have been described in association with T wave inversions on the electrocardiogram. Cardiac memory is a phenomenon characterized by the development of altered T wave polarity on the electrocardiogram when the intrinsic rhythm resumes after a period of abnormal myocardial activation. Misdiagnosis of this condition often leads to unwarranted diagnostic workup and therapeutic interventions. Herein we report a case of 81-year-old female patient with intermittent left bundle branch block presenting with new onset T wave inversions in anterior leads.","PeriodicalId":15510,"journal":{"name":"Journal of Clinical Cardiology","volume":"29 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2017-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79753343","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
K. Pinar, Dagli Necati, Balci Tansel Ansal, Karaca Ilgin, Kepenek Ferat, Cakmak Tolga
{"title":"Adenosine Stress Myocardial Perfusion Scintigraphy and Echocardiography Application with Same Infusion","authors":"K. Pinar, Dagli Necati, Balci Tansel Ansal, Karaca Ilgin, Kepenek Ferat, Cakmak Tolga","doi":"10.23937/2378-2951/1410106","DOIUrl":"https://doi.org/10.23937/2378-2951/1410106","url":null,"abstract":"Objective: Stress Echocardiography (Echo) and Myocardial Perfusion Scintigraphy (MPS) are effective methods for identification of myocardial ischemia. Aim of this study was to compare adenosine stress MPS and Echo results with gold standard angiography. Methods: Twenty nine patients (18 F, 11 M; mean: 49, 62 ± 10, 9; 45, 5-53, 8-years-old) with suspicion of Coronary Artery Disease (CAD) were included into the study. After performance of basal Echo examination, adenosine infusion was started (140 μgr/kg/dk) and at the third minute after starting the infusion, intravenous Tc-99m MIBI injection was performed and stress Echo findings were recorded at the 10th minute. Stress and rest imaging were performed at the same day. Stress Echo was performed by an experienced cardiologist and MPS results were interpreted by an experienced nuclear medicine physician who didn’t know stress Echo results according to 17 segment models. Sixteen patients underwent coronary angiography. Ischemia territory size in both the adenosine stress Echo and MPS were recorded and compared in segment and in patient basis. Results: There were 34 ischemic segments in MPS and 46 in stress Echo among 493 segments of 29 patients. Both MPS and stress Echo pointed the same ischemic segments in 9 patients and tests were in agreement in 24 patients. Angiography confirmed two tests results in 13/16 patients. Three patients with severe ischemia in the MPS and stress Echo had slow flow pattern in the angiography. Conclusion: The results of both MPS and stress Echo with same adenosine infusion was in agreement especially in patients with angiography results. These findings can encourage simultaneous studies with same stress agent infusion.","PeriodicalId":15510,"journal":{"name":"Journal of Clinical Cardiology","volume":"16 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2017-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76743766","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Y. Khaykin, P. Alipour, Meysam Pirbaglou, P. Ritvo, Z. Azizi, Z. Wulffhart, B. Whaley, David Giewercer, K. Winger, A. Verma
{"title":"A Feasibility Pilot Study to Assess the Efficacy of NavX Guided Detection of Pulmonary Vein Electrograms during Atrial Fibrillation Ablation [NavX Guided Detection of Pulmonary Vein Electrograms]","authors":"Y. Khaykin, P. Alipour, Meysam Pirbaglou, P. Ritvo, Z. Azizi, Z. Wulffhart, B. Whaley, David Giewercer, K. Winger, A. Verma","doi":"10.23937/2378-2951/1410102","DOIUrl":"https://doi.org/10.23937/2378-2951/1410102","url":null,"abstract":"Background: Pulmonary Vein Antrum Isolation (PVAI) targeting PV triggers is an established treatment for paroxysmal Atrial Fibrillation (AF). Ablation lesions are typically delivered around the entire circumference of each individual PV. This study tested a strategy where electrical inputs to the PVs were mapped using the NavX system and selectively targeted before ablation. The objectives of the study were to evaluate: 1) Likelihood of PV isolation using this strategy, 2) Correlation between manually tagged PV potentials and Complex Fractionated Electrograms identified using the NavX CFE Mean Map in sinus rhythm and during coronary sinus pacing, 3) Long term success of this strategy. Methods: Ablation was initially guided by identification of PV antral regions activating early in sinus rhythm and during Coronary Sinus (CS) pacing, and exhibiting local fractionated electrograms, mapped using the NavX system, and a circular mapping catheter. If PV isolation could not be established using this approach, it was completed using the conventional ablation approach. For analysis each vein was divided into quadrants from 12 o’clock looking from the Left Atrium (LA) into the vein. Manually identified fractionated potentials were compared with the NavX Complex Fractionated Electrogram (CFE) Mean map acquired in sinus rhythm and during coronary sinus pacing. CFE Mean Map parameters were set to a Width of 20 ms, Refractory of 30 ms, and P-P sensitivity of 0.05 mV. Manually tagged PV potentials were used as the gold standard. AF recurrences were assessed using ambulatory monitoring at 1, 3, 6 & 12 months post ablation. Results: Twenty consecutive patients with paroxysmal AF (age 59 ± 10 y, 60% male, LA 40 ± 6 mm) were enrolled in the study. Distribution of CFE closely paralleled activation. In addition, CFE were identified on the septum in sinus rhythm in 60% of the patients and on the posterior wall during CS pacing in 35% of the patients. The sensitivity-specificity of the auto-identified CFE that predicted manually tagged fractionated potentials were 60%-68% in Sinus Rhythm (SR), and 80%-70% during CS pacing. Mapping and ablation fluoroscopy time was 30 ± 12 min with Radio Frequency (RF) time of 27 ± 10 min. Completion of PVAI required an additional 22 ± 16 min of fluoroscopy and 31 ± 28 min of RF energy delivery. Total procedure time was 209 ± 36 min. Only 13 (4%) of all PV quadrants in n = 5 (25%) patients did not have to be ablated to achieve PVAI. Three patients (15%) had AF recurrences between the first 3 months and 12 months following ablation. Two of these patients cumulatively had 7 of the 13 non-ablated quadrants in the study. Conclusions: While mapping earliest PV activation during sinus rhythm and CS stimulation is feasible, ablation guided by this approach may avoid unnecessary RF energy delivery in only a small proportion of the PV antral segments, potentially leading to higher ablation failure rates. NavX CFE mean algorithm accurately identif","PeriodicalId":15510,"journal":{"name":"Journal of Clinical Cardiology","volume":"94 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2017-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73865793","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}