Journal of Clinical and Experimental Cardiology最新文献

{"title":"Why maze procedure should be performed during cardiac surgery","authors":"O. García-Villarreal","doi":"10.4172/2155-9880-c2-091","DOIUrl":"https://doi.org/10.4172/2155-9880-c2-091","url":null,"abstract":"","PeriodicalId":15504,"journal":{"name":"Journal of Clinical and Experimental Cardiology","volume":"25 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81172167","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"And if the Ventricle was Innocent?: The Rare Case of the Guilty Atrium","authors":"G. Cimino, A. Abbate, G. Teresi, D. Piraino","doi":"10.4172/2155-9880.1000577","DOIUrl":"https://doi.org/10.4172/2155-9880.1000577","url":null,"abstract":"The literature is full of clinical cases related to the giant left atrium (GLA), which is a cause of compression of the left ventricle, giving related symptoms including dyspnea, dysphagia and atrial fibrillation. \u0000In these settings we are presenting though an interesting case report of a patient of 82 years old man with an abnormal enlarged left atrium, who was admitted by our department for aggravated dyspnea. \u0000The transthoracic echocardiogram performed in our department showed a surprisingly dilated left atrium and compressed left ventricle which over time caused dyspnea, with significant images. \u0000Therefore, we conclude that the incomplete and inadequate ventricular filling, causing the diastolic dysfunction, are caused by compression of the left ventricle from the huge left atrium.","PeriodicalId":15504,"journal":{"name":"Journal of Clinical and Experimental Cardiology","volume":"86 1","pages":"1-2"},"PeriodicalIF":0.0,"publicationDate":"2018-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80662843","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Scandinavian Real Heart (SRH) 11 Implantation as Total Artificial Heart (TAH)-Experimental Update","authors":"Z. Szabó, J. Holm, A. Najar, G. Hellers, I. L. Pieper, H. Ahn","doi":"10.4172/2155-9880.1000578","DOIUrl":"https://doi.org/10.4172/2155-9880.1000578","url":null,"abstract":"One Swedish Landrace pig weighting approximately 80 kg was used to implant the SRH11. In this experiment the main focus was on the details of anesthesia as well as the mechanical function of the SRH11. The main finding from this study is that the SRH11 can deliver a wide range of cardiac output with a pulsatile waveform similar to the flow pattern of the native heart. In the anesthesia the following issues are of major importance from clinical point of view: the fluid balance and the adequate perfusions pressure is a high priority; The kidneys may be protected by a moderate dose of furosemide and measurement of urine output is mandatory; The systemic inflammatory reaction has to be controlled; At the weaning from the CPB the animal needs transfusion, therefore fresh blood should be available.","PeriodicalId":15504,"journal":{"name":"Journal of Clinical and Experimental Cardiology","volume":"105 1","pages":"1-4"},"PeriodicalIF":0.0,"publicationDate":"2018-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88660416","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of Sleep and Mood Symptoms in Patients with Undetected Obstructive Sleep Apnea and Atrial Fibrillation","authors":"Asmaa M Abumuamar, P. Dorian, D. Newman, C. Shapiro","doi":"10.4172/2155-9880.1000572","DOIUrl":"https://doi.org/10.4172/2155-9880.1000572","url":null,"abstract":"Introduction: Obstructive sleep apnea (OSA) is associated with serious cardiovascular consequences. We aimed to determine: • The percentage of patients in arrhythmia clinics who show symptoms suggestive of insomnia, non-refreshing sleep, excessive daytime sleepiness, fatigue, decreased alertness, and/or depression; • If these symptoms predict the severity or the presence of OSA in these patients. Methods: Non-selected consecutive patients were recruited from outpatient arrhythmia clinics. Patients with previously diagnosed and/or treated OSA were excluded. Validated screening tools were administered. Patients underwent ambulatory sleep testing for the diagnosis of OSA. Correlation and regression analyses were performed to detect the predictors of OSA. Results: 100 participants with atrial fibrillation were recruited (72% Males). The mean age was 64 ± 13 years. Sleep related instruments showed that: • Thirty-seven percent of patients have scores suggestive of excessive daytime sleepiness; • Fifty-four percent have excessive daytime fatigue; • Symptoms of non-restorative sleep are present in 57%; • Twenty-five percent have scores suggestive of depression; • Thirty-eight percent have mild insomnia, 14% moderate insomnia, and 5% severe insomnia; • Six percent show scores suggestive of decreased alertness. Eighty-five percent of patients had previously undetected OSA. Only age and male gender were predictors of OSA (p=0.009, p=0.008 respectively). Conclusion: Eighty-five percent of patients with atrial fibrillation have undetected OSA. Scores suggestive of daytime sleepiness, fatigue, insomnia, depression, and non-refreshing sleep do not predict OSA. Sleep studies may be applied routinely for detection of OSA in these patients.","PeriodicalId":15504,"journal":{"name":"Journal of Clinical and Experimental Cardiology","volume":"448 1","pages":"1-6"},"PeriodicalIF":0.0,"publicationDate":"2018-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75810427","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Differential Diagnosis of Transient Left Ventricular Dysfunction in a Critically Ill Patient","authors":"A. Jayaraj, S. Ganesan","doi":"10.4172/2155-9880.1000571","DOIUrl":"https://doi.org/10.4172/2155-9880.1000571","url":null,"abstract":"There is evidence illustrating that the etiologies of non-ischemic LV (left ventricular) dysfunction such as Takotsubo cardiomyopathy, neurogenic stunning myocardium and post resuscitation stunning myocardium have a favorable clinical outcome. Good prognosis in non-ischemic LV dysfunction provides us courage to treat the condition expecting good. We describe herein the unique case of a 33-year-old woman who was started on combination chemotherapy of oxaliplatin and 5-flurouracil for colon adenocarcinoma. The patient’s baseline QTc was 460 ms. Twenty-four hours following initiation of chemotherapy, the patient developed 3 discrete episodes of tonicclonic seizures. Electrocardiogram assessment demonstrated a prolonged QTc interval (623 ms) with several episodes of TdP. Two episodes required defibrillation to revert to sinus rhythm. Post resuscitation echocardiogram showed severe global LV dysfunction with ejection fraction of 33%. The patient subsequently required mechanical ventilation due to severe LV dysfunction with pulmonary edema. Possible etiologies for LV dysfunction in the present case include global Takotsubo cardiomyopathy, neurogenic stunning myocardium or post resuscitation stunning myocardium. Repeat echocardiogram 48 h later showed the ejection fraction of 60%. Although myocardial dysfunction associated with Takotsubo cardiomyopathy, neurogenic stunning myocardium and post resuscitation stunning myocardium have been previously described independently, the present case is unique in that, to our knowledge, torsade de pointes presented with transient left ventricular dysfunction following several episodes of seizures and post resuscitation stunning myocardium that were stabilized in one patient following oxaliplatin and 5- fluorouracil infusion has not been reported.","PeriodicalId":15504,"journal":{"name":"Journal of Clinical and Experimental Cardiology","volume":"28 1","pages":"1-3"},"PeriodicalIF":0.0,"publicationDate":"2018-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77444273","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Effect of Left Ventricular Geometry on Myocardial Performance Index in Hypertensive Patients","authors":"Tarek Elmasry, Mohammed F Abd-Elbary, K. Marghany, M. Abo-Elmagd","doi":"10.4172/2155-9880.1000567","DOIUrl":"https://doi.org/10.4172/2155-9880.1000567","url":null,"abstract":"Background: The relationship between Tei Index (TI) and left ventricular (LV) geometric patterns has not been previously well described. The present study therefore set out to describe the nature of this relationship. This study examined the association between the Tei index and left ventricular geometry among hypertensive Egyptian subjects. \u0000Methods: This study included 70 subjects (60 hypertensive Patients and 10 control subjects). Hypertensive Patients and control subjects were referred from outpatient clinic to the Echocardiographic laboratory of Cardiovascular Department in Almataria Teaching Hospital between April 2017-November 2017. TI was defined as the sum of isovolumic contraction and relaxation times divided by the ejection time, and values of LV TI<0.40 were considered normal, while higher values were considered abnormal. Four patterns of LV geometry (normal, concentric remodeling, concentric LV hypertrophy and eccentric LV hypertrophy) were determined from the LV mass index and LV relative wall thickness. Statistical analysis was done using SPSS version 20.0. Bivariate correlation and stepwise multiple linear regressions were used to analyze the associations between TI and a number of variables. \u0000Results: Among the hypertensive subjects, Concentric hypertrophy was the commonest pattern of abnormal geometry (36.7%), followed by eccentric hypertrophy (20%), and concentric remodeling was demonstrated in 15% of the hypertensive population. Only 28.3% of the hypertensive population had normal geometry. Hypertensive patients with normal geometry had the highest Tei index. Those with concentric hypertrophy had higher Tei index than those with concentric remodelling. However, there was no significant difference in the Tei index between those with eccentric and concentric hypertrophy. In correlation between MPI and Echocardiography variables of LVH of hypertensive patients in bivariate correlation had a direct statistically significant with LVPWDd, IVSDd, LVIDd, LVISd, LV mass & LVMI. The MPI had inverse significant correlation with EF and FS. While by using stepwise multiple linear regressions the predictor of MPI was the LV mass index. \u0000Conclusion: This study has found that MPI is impaired in hypertensive patients before development of ventricular hypertrophy and in left ventricular hypertrophy is more prominent in concentric hypertrophy.","PeriodicalId":15504,"journal":{"name":"Journal of Clinical and Experimental Cardiology","volume":"150 1","pages":"1-5"},"PeriodicalIF":0.0,"publicationDate":"2018-02-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86151054","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Improved Coronary Sinus Blood Sampling for Cardiac Research","authors":"S. Dawkins, M. Alkhalil, G. L. Maria, G. Fahrni, G. Kassimis, Regent Lee, N. Patel, A. Banning, R. Choudhury, C. Forfar, R. Kharbanda, J. Langrish, A. Lucking, K. Channon","doi":"10.4172/2155-9880.1000568","DOIUrl":"https://doi.org/10.4172/2155-9880.1000568","url":null,"abstract":"Background: Coronary sinus (CS) blood sampling is important for measuring metabolites and biomarkers in cardiovascular research, but can be technically challenging. Here we demonstrate the use of the antecubital fossa for CS blood sampling as an alternative to femoral access, and a simple technique of paired venous and CS blood gas analysis for confirmation of valid CS sampling. We also demonstrate improvement in sampling accuracy by using a coronary guide wire to stabilize the sampling catheter in the CS.Methods: Paired blood samples from CS and peripheral vein were collected from patients at the time of primary PCI for acute myocardial infarction. Venous access for CS sampling was via the antecubital vein. Blood gas analysis was used to confirm a true CS sample (pO2[CS]<pO2[v]). CS sampling was carried out with a catheter in the CS (standard technique) or with the addition of a coronary guide wire for stability (modified technique).Results: 108 patients underwent CS and peripheral venous blood sampling. The standard technique for CS sampling was used in 62 patients and the modified technique in 46 patients. Blood gas analysis confirmed a true CS sample in 77% of patients using the standard technique and 100% using the modified technique.Conclusions: CS blood sampling via the antecubital fossa is feasible and safe. Blood gas analysis of paired venous and CS samples can be used to confirm a valid CS sample. A coronary guide wire can be used to stabilise the sampling catheter in the CS, and this increases CS sampling accuracy.","PeriodicalId":15504,"journal":{"name":"Journal of Clinical and Experimental Cardiology","volume":"13 1","pages":"1-3"},"PeriodicalIF":0.0,"publicationDate":"2018-02-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88016323","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"QT Dispersion Changes Following Primary Percutaneous Coronary Intervention in Acute Myocardial Infarction Comparison between Primary PCI Plus Thrombectomy and Primary PCI without Thrombectomy","authors":"Timoor Hassan, M. Omar, A. Alarag","doi":"10.4172/2155-9880.1000595","DOIUrl":"https://doi.org/10.4172/2155-9880.1000595","url":null,"abstract":"Objective: The aim of this study was to compare between primary PCI plus thrombectomy and primary PCI without thrombectomy on QT dispersion in patients presented with acute STEMI. Methods: Forty-eight patients presenting with acute STEMI who underwent primary percutaneous coronary intervention (PCI) were enrolled. QTc and QTd were calculated before, and 24 hours after the procedure. Results: 48 patients (33 males, 15 females) with a mean age of 58.6 ± 11.0 years were evaluated. The results showed significant reduction in both QTd 80.60 ± 10.14 ms vs. 44.80 ± 9.46 ms; p<0.001 and QTc d 87.00 ± 7.00 vs. 40.40 ± 8.00 ms before and 24 hours after primary PCI. QTd and QTc dispersion values were decreased slightly more in PPCI plus thrombectomy group than the PPCI alone group but were not statistically significant (p value 0.067 and 0.091) respectively. Conclusion: Our Study showed that primary PCI was effective in reducing QTc and QTd after 24 h and no significant difference on QTc and QTd whether thrombectomy used or not. These findings suggest that ischemiainduced QTd and prolonged QTc are important arrhythmogenic parameters which respond to successful PPCI and may be used as markers for successful PPCI after 24 h.","PeriodicalId":15504,"journal":{"name":"Journal of Clinical and Experimental Cardiology","volume":"3 1","pages":"1-6"},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85924255","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Utility of Atherogenic Index of Plasma in Predicting Plaque Burden in Patients with Chest Pain and Intermediate Pretest Probability of Coronary Artery Disease","authors":"R. Mahfouz, M. Goda, I. Galal, M. Ghareeb","doi":"10.4172/2155-9880.1000603","DOIUrl":"https://doi.org/10.4172/2155-9880.1000603","url":null,"abstract":"Objective: We aimed to explore the utility of atherogenic index of plasma (AIP) on plaque burden detected by coronary computed tomography angiography (CCTA) in patients with chest pain and intermediate probability of coronary artery disease (CAD). Methods: AIP was calculated as the logarithmically transformed ratio of the serum triglycerides to HDLcholesterol in 167 patients with chest pain (age 46.5 ± 11.8 yrs; 104 were men) and correlated with segment stenosis score (SSS), SIS and total plaque score (TPS), studied with CCTA, and compared with other lipid ratios. Results: Obstructive CAD lesions were detected in 45.5% of patients with intermediate pretest probability of CAD. CCTA documented CAD was detected in 61.7% subjects with AIP value >0.24, while CAD was detected in 26.5% patients with AIP value <0.24. AIP was 0.49 ± 0.12 in patients with CAD versus 0.14 ± 0.03; p<0.001 in those without CAD. The total coronary artery calcium score (CACS) was significantly higher in patients with AIP >0.24 than in patients with AIP <0.24 (p<0.001). AIP was correlated with SSS, SIS, TPS, and CACS (p<0.001). Moreover, it seems to be the strongest ratio than other lipid ratios. AIP was the strongest predictor of plaque burden. ROC analysis demonstrated that AIP >0.29 was the optimal cut-off value in predicting CAD, with AUC=0.78, p<0.001, and it was the strongest discriminator index compared with other lipid indices. Conclusion: AIP was significantly correlated with plaque burden and extent of CAD in patients with intermediate pretest probability of CAD who presented with chest pain and it could help in risk stratification.","PeriodicalId":15504,"journal":{"name":"Journal of Clinical and Experimental Cardiology","volume":"26 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80870917","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Tuberculosis Pericarditis: Case Report","authors":"Chaudappa Shakapur, Sagar Mali","doi":"10.4172/2155-9880.1000609","DOIUrl":"https://doi.org/10.4172/2155-9880.1000609","url":null,"abstract":"Tubercular pericarditis manifesting as cardiac tamponade with large pericardial effusion is relatively rare. We report a case of cardiac tamponade due to tubercular pericardial effusion with severe left ventricular systolic dysfunction.","PeriodicalId":15504,"journal":{"name":"Journal of Clinical and Experimental Cardiology","volume":"13 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78948541","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}