Journal of Clinical and Experimental Cardiology最新文献_第10页

Why Treat Chronic Total Occlusion without Stents? - A Short Comment 为什么不使用支架治疗慢性全闭塞?-简短评论

Journal of Clinical and Experimental Cardiology Pub Date : 2017-06-20 DOI: 10.4172/2155-9880.1000529

P. Köln, F. Kleber

引用次数: 2

The Effect of High-Dose Simvastatin Therapy on Patients with Acute Cerebral Infarction 大剂量辛伐他汀治疗急性脑梗死的疗效观察

Journal of Clinical and Experimental Cardiology Pub Date : 2017-06-13 DOI: 10.4172/2155-9880.1000527

Xiaozhu Liu, Huankun Liang, Kangyan Li, Jiali Li, Lai-qing Li, Licheng Zhang

{"title":"The Effect of High-Dose Simvastatin Therapy on Patients with Acute Cerebral Infarction","authors":"Xiaozhu Liu, Huankun Liang, Kangyan Li, Jiali Li, Lai-qing Li, Licheng Zhang","doi":"10.4172/2155-9880.1000527","DOIUrl":"https://doi.org/10.4172/2155-9880.1000527","url":null,"abstract":"Cerebrovascular disease (CVD) accounts for the major cause of morbidity and mortality in industrialized countries. However, effects of high-dose simvastatin therapy on patients with acute cerebral infarction still unclear. In this study, the clinical efficacy of high-dose simvastatin on patients with cerebral infarction was investigated. A total of 180 patients with acute cerebral infarction were randomized divided into control group (n=60), high-dose simvastatin (HDS) group (n=60) and low-dose simvastatin (LDS) group (n=60). Control group, HDS group and LDS group received conventional treatment, conventional treatment together with simvastatin 80 mg/d and conventional treatment as well as simvastatin 40 mg/d respectively for 3 months. Biochemical indices, neurological deficit and plaque thickness and volume were assessed and recorded after treatment. After simvastatin treatment, the plasma levels of Triglyceride, Total cholesterol, Low-density lipoprotein were significantly decreased in HDS group and LDS group, and HDS were significantly increased in HDS group and LDS group. Also, simvastatin decreased levels of IL-6 and TNF-α, two major inflammatory factors in plasma. Furthermore, improved neurological deficit were found in simvastatin treatment groups. In addition, simvastatin treatment also improved plaque states include plaque thickness and volume in HDS group and LDS group. Therefore, simvastatin could improve acute cerebral infarction and high-dose of simvastatin treatment was better than low -dose of simvastatin treatment.","PeriodicalId":15504,"journal":{"name":"Journal of Clinical and Experimental Cardiology","volume":"20 1","pages":"1-4"},"PeriodicalIF":0.0,"publicationDate":"2017-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73789057","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Trans Ulnar Approach for Unprotected Left Main Coronary Artery Disease 经尺侧入路治疗无保护的左主干冠状动脉疾病

Journal of Clinical and Experimental Cardiology Pub Date : 2017-06-10 DOI: 10.4172/2155-9880.1000526

R. Gokhroo, Shashikant Pandey, A. Avinash, Ramsagar, Kailash

引用次数: 0

Challenges of Anomalous Coronary Artery Intervention: Case Series and a Review 冠状动脉异常介入治疗的挑战:病例系列和综述

Journal of Clinical and Experimental Cardiology Pub Date : 2017-06-03 DOI: 10.4172/2155-9880.1000525

T. Rabe, A. Bahekar, S. Arora

引用次数: 0

Primary Percutaneous Coronary Intervention through Right Trans-Ulnar Access in a Case of Arteria Lusoria: Feasibility Stamped 经右尺路经皮冠状动脉介入治疗1例:可行性证明

Journal of Clinical and Experimental Cardiology Pub Date : 2017-05-27 DOI: 10.4172/2155-9880.1000524

Ramsagar Roy, Shashikant Kailash, R. Gokhroo

引用次数: 0

Comparative Study of Two Decellularization Protocols on a Biomaterial for Tissue Engineering 组织工程生物材料两种脱细胞方案的比较研究

Journal of Clinical and Experimental Cardiology Pub Date : 2017-05-25 DOI: 10.4172/2155-9880.1000523

S. Sajith

{"title":"Comparative Study of Two Decellularization Protocols on a Biomaterial for Tissue Engineering","authors":"S. Sajith","doi":"10.4172/2155-9880.1000523","DOIUrl":"https://doi.org/10.4172/2155-9880.1000523","url":null,"abstract":"Cardiovascular disease is a major health risk since past decade. Surgical treatment for major heart diseases has been one of the major challenges since years. Cardiac valves are synthetic or bio prosthetic ones. Mechanical valves are long durable but highly thrombogenic and undergo calcification at higher rates demanding permanent anticoagulation, which increases the risk of bleeding. Biomaterial scaffolds are used in surgical replacements but only after decellularization and processing. Decellularization makes tissue less antigenic; reduce inflammatory response and less tissue degeneration. In this work two decellularization protocols are tried on bovine pericardium (BP) to find out the effect of each of them on the scaffold's integrity. BP undergone protocol 1(0.25% Trypsin-EDTA, TritonX-100, Deoxycholic acid, Peracetic acid/Ethanol) treatment was seen to have highly distorted and damaged collagen matrix. Decellularization with protocol 2 (Deoxycholic acid, DNase, RNase, Ethanol) resulted in a completely decellularised bovine pericardium. The extracellular matrix was intact as native one with collagen bundles. This will help cell attachment to the decellularised matrix.","PeriodicalId":15504,"journal":{"name":"Journal of Clinical and Experimental Cardiology","volume":"12 1","pages":"1-3"},"PeriodicalIF":0.0,"publicationDate":"2017-05-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87716254","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

Ventricular Septal Rupture After Acute Myocardial Infarction-Do We Know Which Strategy to Choose? 急性心肌梗死后室间隔破裂——我们知道该选择哪种策略吗?

Journal of Clinical and Experimental Cardiology Pub Date : 2017-05-20 DOI: 10.4172/2155-9880.1000522

A. Ledakowicz-Polak, J. SÅawomir, er, M. Kidawa, K. Stokfisz, Marzenna ZieliÅska

引用次数: 1

Are there Differences between Adolescent Males and Females for Maintaining the Metabolic Cost at Maximal Oxygen Uptake 青少年男性和女性在维持最大摄氧量时的代谢成本方面存在差异吗

Journal of Clinical and Experimental Cardiology Pub Date : 2017-05-20 DOI: 10.4172/2155-9880.1000519

M. Saghiv, Chris Sherve, D. Sira, M. Saghiv, E. Goldhammer

{"title":"Are there Differences between Adolescent Males and Females for Maintaining the Metabolic Cost at Maximal Oxygen Uptake","authors":"M. Saghiv, Chris Sherve, D. Sira, M. Saghiv, E. Goldhammer","doi":"10.4172/2155-9880.1000519","DOIUrl":"https://doi.org/10.4172/2155-9880.1000519","url":null,"abstract":"Purpose: The present study looked at gender difference in oxygen delivery-extraction at maximal oxygen uptake \u0000 in healthy adolescents. \u0000Methods: 36 adolescent males (14.9 ± 1.1 years) and 33 adolescent females (15.0 ± 1.1 years) underwent \u0000 a maximal oxygen uptake test and a two dimensional direct m-mode echocardiography performed on a bicycle \u0000 ergometry. Arteriovenous oxygen difference was defined by utilizing the Fick equation. \u0000Results: At rest, males compared to females had significantly (p<0.05) higher oxygen extraction (38.8 ± 1.4 and \u0000 31.8 ± 1.2 mL.kg-1 .min-1 respectively), systolic blood pressure, and mean arterial blood pressure. At peak exercise \u0000 test, males compared to females demonstrated significant (P<0.05) higher values for cardiac output (16.6 ± 0.7 and \u0000 15.4 ± 0.6 L∙min-1 respectively), stroke volume (83.9 ± 5.1 and 78.5 ± 4.6 mL respectively), oxygen uptake (47.3 ± 3.7 \u0000 and 39.6 ± 1.1 mL∙kg-1∙min-1, respectivel y), while oxygen extraction was significantly higher in females compared to \u0000 males (123.6 ± 7.6 and 115.5 ± 5.4 mL∙L-1 respectively). \u0000Conclusions: This study suggests that normal adolescents; male and females respond to the maximal oxygen \u0000 uptake test by increased their left ventricular systolic function, however, it was less augmented in the females due to \u0000 gender and energy metabolism differences. Consequently, females increased their oxygen extraction more than the \u0000 males as a compensation for the lower cardiac output and hence, lower oxygen delivery.","PeriodicalId":15504,"journal":{"name":"Journal of Clinical and Experimental Cardiology","volume":"9 1","pages":"1-5"},"PeriodicalIF":0.0,"publicationDate":"2017-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87960704","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Percutaneous Aspiration Embolectomy in the Treatment of Acute Arterial Embolic Infrainguinal Vascular Occlusion 经皮穿刺栓子切除术治疗急性动脉栓塞性腹股沟下血管闭塞

Journal of Clinical and Experimental Cardiology Pub Date : 2017-05-20 DOI: 10.4172/2155-9880.1000520

Schleder S, Diekmann M, Manke C, Heiss P

{"title":"Percutaneous Aspiration Embolectomy in the Treatment of Acute Arterial Embolic Infrainguinal Vascular Occlusion","authors":"Schleder S, Diekmann M, Manke C, Heiss P","doi":"10.4172/2155-9880.1000520","DOIUrl":"https://doi.org/10.4172/2155-9880.1000520","url":null,"abstract":"Background: Since its introduction, percutaneous aspiration embolectomy (PAE) has become a well-known, widely accepted and frequently applied technique for the treatment of acute arterial embolic infrainguinal vascular occlusion in lower limb ischemia.Purpose: To evaluate the technical and clinical success of sole percutaneous aspiration embolectomy (PAE) for the treatment of acute arterial embolic infrainguinal vascular occlusion.Material and Methods: During a period of 7 years, 50 patients (24 fermale, 48%) with a mean age of 73 (range 53–95) years were identified in whom 54 cases of PAE were performed for the treatment of arterial embolic infrainguinal vascular occlusion. Primary technical success was defined as residual stenosis of <50% in diameter after sole PAE, secondary technical success was defined as residual stenosis of <50% in diameter after PAE and additional percutaneous transluminal angioplasty (PTA) and/or stenting. Clinical outcome parameters (e.g. need for further intervention and/or amputation) were evaluated for the 30-day postinterventional period.Results: The primary technical success rate was 85% (46 of 54 cases). The secondary technical success rate was 96% (52 of 54 cases). Clinical outcome data were achievable in 50 of the 54 cases (93%). In 43 of the 50 patients (86%) there was no need for further intervention within the 30-day postinterventional period. In summary, during this 30-day postinterventional period after PAE amputation was carried out or death occurred in 5 of 50 patients (10%).Conclusion: Minimally invasive PAE is an effective and safe technique for the treatment of acute arterial embolic infrainguinal vascular occlusion.","PeriodicalId":15504,"journal":{"name":"Journal of Clinical and Experimental Cardiology","volume":"11 1","pages":"1-4"},"PeriodicalIF":0.0,"publicationDate":"2017-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84902888","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

One, Two, Three: Stepwise Treatment of a Large DVT in a 53 Year Old Femalewith May-Thurner 一，二，三:53岁女性May-Thurner大DVT的分步治疗

Journal of Clinical and Experimental Cardiology Pub Date : 2017-05-20 DOI: 10.4172/2155-9880.1000521

M. H. Makki

引用次数: 0