急性心肌梗死经皮冠状动脉介入治疗后QT离散度的变化与经皮冠状动脉介入治疗加取栓与不取栓的比较

Timoor Hassan, M. Omar, A. Alarag
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引用次数: 3

摘要

目的:本研究的目的是比较急性STEMI患者首次PCI +取栓与不取栓对QT离散度的影响。方法:48例急性STEMI患者接受了经皮冠状动脉介入治疗(PCI)。术前和术后24h分别计算QTc和QTd。结果:48例患者(男33例,女15例),平均年龄58.6±11.0岁。结果显示,QTd(80.60±10.14 ms)和QTd(44.80±9.46 ms)均显著降低;p<0.001, QTc d分别为87.00±7.00 ms和40.40±8.00 ms。PPCI联合取栓组QTd和QTc离散度值下降幅度略大于单独PPCI组,但差异无统计学意义(p值分别为0.067和0.091)。结论:我们的研究表明,首次PCI可有效降低24 h后的QTc和QTd,无论是否取栓,QTc和QTd均无显著差异。上述结果提示,缺血QTd和QTc延长是诱发PPCI成功的重要心律失常参数,可作为24 h后PPCI成功的标志。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
QT Dispersion Changes Following Primary Percutaneous Coronary Intervention in Acute Myocardial Infarction Comparison between Primary PCI Plus Thrombectomy and Primary PCI without Thrombectomy
Objective: The aim of this study was to compare between primary PCI plus thrombectomy and primary PCI without thrombectomy on QT dispersion in patients presented with acute STEMI. Methods: Forty-eight patients presenting with acute STEMI who underwent primary percutaneous coronary intervention (PCI) were enrolled. QTc and QTd were calculated before, and 24 hours after the procedure. Results: 48 patients (33 males, 15 females) with a mean age of 58.6 ± 11.0 years were evaluated. The results showed significant reduction in both QTd 80.60 ± 10.14 ms vs. 44.80 ± 9.46 ms; p<0.001 and QTc d 87.00 ± 7.00 vs. 40.40 ± 8.00 ms before and 24 hours after primary PCI. QTd and QTc dispersion values were decreased slightly more in PPCI plus thrombectomy group than the PPCI alone group but were not statistically significant (p value 0.067 and 0.091) respectively. Conclusion: Our Study showed that primary PCI was effective in reducing QTc and QTd after 24 h and no significant difference on QTc and QTd whether thrombectomy used or not. These findings suggest that ischemiainduced QTd and prolonged QTc are important arrhythmogenic parameters which respond to successful PPCI and may be used as markers for successful PPCI after 24 h.
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