Journal of Contemporary Pharmacy Practice最新文献_第9页

A review on smart bioresponsive drug delivery systems 智能生物反应给药系统研究进展

Journal of Contemporary Pharmacy Practice Pub Date : 2019-07-31 DOI: 10.56770/jcp2019315

Kainat Haleem, Muhammad Arslan Khan

引用次数: 0

Association Between Sleep Medications and Falls and Fall-related Worries in Community-Dwelling Older Adults in the United States 在美国社区居住的老年人中，睡眠药物与跌倒和跌倒相关担忧之间的关系

Journal of Contemporary Pharmacy Practice Pub Date : 2019-06-01 DOI: 10.37901/jcphp18-00022

Kathy Nguyen, J. Watanabe

{"title":"Association Between Sleep Medications and Falls and Fall-related Worries in Community-Dwelling Older Adults in the United States","authors":"Kathy Nguyen, J. Watanabe","doi":"10.37901/jcphp18-00022","DOIUrl":"https://doi.org/10.37901/jcphp18-00022","url":null,"abstract":"Background\u0000\u0000Falls are the leading cause of unintentional fatal and nonfatal injuries in seniors. Sleep medications are associated with adverse events risk in older adults. The objective of this study is to quantify the relationship between different levels of sleep medication use with falls and fall-related worries in United States adults aged 65 years and older using a nationally representative sample.\u0000\u0000Methods\u0000\u0000Using the 2011 National Health and Aging Trends Study, survey-weighted multiple logistic regression was used to determine the association between participants who reported sleep medication use and the outcomes: falls in the last month, falls in the last year, multiple falls in the last year, fall-related worries, and limitation of activities due to fall-related worries.\u0000\u0000Results\u0000\u0000In adjusted analyses, older adults who used sleep medications every night compared to non-users of sleep medications were at increased odds of falls in the last year with an odds ratio (OR) of 1.51 (95% confidence limit [CL] 1.27, 1.78) and of multiple falls with an OR = 1.67 (95% CL 1.35, 2.06). For those who used sleep medications less than every night compared to non-users, there were no statistically significant increased odds of fall outcomes. Older adults who used sleep medication most nights (5–6 nights per week) and every night compared to non-users had increased odds of having fall-related worries with an OR = 1.61 (95% CL 1.06, 2.45) and an OR = 1.32 (95% CL 1.11, 1.58), respectively.\u0000\u0000Conclusion\u0000\u0000Older adults who use sleep medication every night are at greater odds of experiencing falls and having fall-related worries. Increased involvement by pharmacists in the community setting and pharmacist-led comprehensive medication reviews are efforts that may reduce sleep medication use and result in fewer falls in older adults.","PeriodicalId":15502,"journal":{"name":"Journal of Contemporary Pharmacy Practice","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44772245","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Pharmacologic Treatment of Hypertension in Adults Aged 60 Years or Older from the American College of Physicians and the American Academy of Family Physicians 来自美国医师学会和美国家庭医师学会的60岁或60岁以上成年人高血压的药理学治疗

Journal of Contemporary Pharmacy Practice Pub Date : 2019-06-01 DOI: 10.37901/jcphp17-00017

Eric Pinashin, C. Stern

引用次数: 1

Tools for Community-Based Pharmacist Patient Care Services to Support Optimal Opioid Use 社区药剂师患者护理服务工具，支持阿片类药物的最佳使用

Journal of Contemporary Pharmacy Practice Pub Date : 2019-06-01 DOI: 10.37901/jcphp18-00005

T. Gregorian, Nancy Alvarez, Krystal Han, Marl Ayson, M. Durham

引用次数: 0

Recognizing Emerging Roles: Effective Delegation to and Supervision of Pharmacy Technicians for a More Efficient and Effective Pharmacy Organization 认识到新出现的角色：有效授权和监督药房技术人员，以建立更高效、更有效的药房组织

Journal of Contemporary Pharmacy Practice Pub Date : 2019-06-01 DOI: 10.37901/jcphp18-00025

Mustafa Sultani, Sam Pournezhad, S. Desselle, Bushra Alsharif, Muhamod Saied, Ryan Hoh

{"title":"Recognizing Emerging Roles: Effective Delegation to and Supervision of Pharmacy Technicians for a More Efficient and Effective Pharmacy Organization","authors":"Mustafa Sultani, Sam Pournezhad, S. Desselle, Bushra Alsharif, Muhamod Saied, Ryan Hoh","doi":"10.37901/jcphp18-00025","DOIUrl":"https://doi.org/10.37901/jcphp18-00025","url":null,"abstract":"Purpose\u0000\u0000To describe current and emerging roles of technicians, including advanced roles that might help free up pharmacists' time to participate in direct patient care; discuss the supervision of technicians as knowledge workers who recognize their own aspirations for self-development; and discuss maximizing the effectiveness of the pharmacy workforce support team to advance care for patients and help ensure longevity of this workforce for the organization and for the profession.\u0000\u0000Conclusion\u0000\u0000Technicians are a key part of the pharmacy team. Their education and training has lacked standardization; however, this is beginning to change as the result of stricter state licensing requirements and newer laws that better define and expand the technician's responsibilities. These newer and expanded technician responsibilities and the education required will only further enhance their value to the pharmacy organization. These newer roles and responsibilities should endeavor a win-win-win for pharmacists, technicians [and other support staff], and patients.","PeriodicalId":15502,"journal":{"name":"Journal of Contemporary Pharmacy Practice","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48687016","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Alemtuzumab Associated Listeria Monocytogenes Meningitis 阿仑单抗相关性单核细胞增生李斯特菌脑膜炎

Journal of Contemporary Pharmacy Practice Pub Date : 2019-06-01 DOI: 10.37901/jcphp18-00023

Corrie Black, Ryan Stevens, M. Clancy, Shari Morgan, Mary-Margaret Hillstrand

{"title":"Alemtuzumab Associated Listeria Monocytogenes Meningitis","authors":"Corrie Black, Ryan Stevens, M. Clancy, Shari Morgan, Mary-Margaret Hillstrand","doi":"10.37901/jcphp18-00023","DOIUrl":"https://doi.org/10.37901/jcphp18-00023","url":null,"abstract":"Purpose\u0000Describe a case of Listeria monocytogenes meningitis following initiation of alemtuzumab therapy in a patient diagnosed with relapsing–remitting multiple sclerosis (RRMS).\u0000\u0000Summary\u0000A 44-year-old female presented with headache and fever seven days after completion of an initial course of alemtuzumab for the treatment of RRMS. Blood cultures were positive for gram-positive bacilli. A lumbar puncture revealed cell counts, consistent with bacterial meningitis and magnetic resonance imaging (MRI) revealed abnormal signal enhancement of the left cingulate gyrus. Vancomycin, ceftriaxone, and ampicillin were initiated empirically. Both blood and cerebrospinal fluid cultures resulted positive for Listeria monocytogenes. Antibiotics were narrowed to ampicillin for a treatment duration of 21 days, after which symptoms resolved and she was transitioned home. Alemtuzumab is a CD52-directed cytolytic monoclonal antibody that has previously been implicated in association with cases of Listeria monocytogenes meningitis in other countries. Based on its mechanism of action, previous association, and positive temporal relationship, we hypothesize that alemtuzumab played a substantial role in the development of L. monocytogenes meningitis in this patient.\u0000\u0000Conclusion\u0000To our knowledge, this is the first reported case of alemtuzumab associated Listeria meningitis in the United States. This case highlights the severe lymphopenia associated with alemtuzumab therapy and risk of subsequent opportunistic infection. Heightened vigilance in counseling and monitoring of dietary restrictions is critical both prior to and during alemtuzumab therapy. A greater role of prophylactic antibiotics may also be warranted.","PeriodicalId":15502,"journal":{"name":"Journal of Contemporary Pharmacy Practice","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44212826","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Factors Associated with Unintended Pregnancy, Contraceptive Risk-Taking, and Interest in Pharmacist-Provided Birth Control 与意外怀孕、避孕风险和药剂师对节育的兴趣相关的因素

Journal of Contemporary Pharmacy Practice Pub Date : 2019-06-01 DOI: 10.37901/10.37901/jcphp18-00013

Tara Walker, D. Colayco, R. Yacobi, Grant Lawless

引用次数: 1

Impact of Initiating Clinical Pharmacy Services in a Non-Academic Community Medical Center Emergency Department Setting 在非学术社区医疗中心急诊科设置启动临床药学服务的影响

Journal of Contemporary Pharmacy Practice Pub Date : 2019-06-01 DOI: 10.37901/jcphp17-00029

J. Pouliot, Martin Hahn, Bryan Sharpe

引用次数: 0

Threats and Opportunities Abound in the Profession 职业中的威胁与机遇

Journal of Contemporary Pharmacy Practice Pub Date : 2019-06-01 DOI: 10.37901/jcphp19-00ee2

Jon Roth

引用次数: 0

Type 2 Diabetes Mellitus in Patients with a Prior History of Corticosteroid-induced Hyperglycemia 有皮质类固醇诱导的高血糖病史的2型糖尿病患者

Journal of Contemporary Pharmacy Practice Pub Date : 2019-03-01 DOI: 10.37901/jcphp17-00023

Jennifer DeZubay, R. Drew, Jennifer Smith, E. Mills, Tara Bell, M. Holland

{"title":"Type 2 Diabetes Mellitus in Patients with a Prior History of Corticosteroid-induced Hyperglycemia","authors":"Jennifer DeZubay, R. Drew, Jennifer Smith, E. Mills, Tara Bell, M. Holland","doi":"10.37901/jcphp17-00023","DOIUrl":"https://doi.org/10.37901/jcphp17-00023","url":null,"abstract":"also been observed in healthy subjects. (3) Prednisone, prednisolone, and methylprednisolone are intermediate-acting corticosteroids with a peak effect four to six hours after administration. (1)(2) After just one dose, postprandial blood glucose may be affected without much effect on fasting blood glucose. (1) However, after repeated doses, these intermediate-acting corticosteroids can cause persistent hyperglycemia. (1) Dexamethasone, a long-acting corticosteroid, is associated with hyperglycemia that may persist for longer than 24 hours. (1) High doses of corticosteroids, defined as more than 30 mg of prednisone equivalent per day, lead to more adverse effects, such as hyperglycemia. (5) Likewise, many adverse effects, including glucose intolerance, are related to the cumulative corticosteroid dose and longer duration of corticosteroid use. A prospective, observational study of 35 patients without pre- existing diabetes, taking high-dose corticosteroids for 6 to 12 weeks, found 40.6% of patients to have elevated fasting or postprandial blood glucose at eight weeks (fasting blood glucose >126 mg/dL). (6) Both higher cumulative corticosteroid doses and continuous corticosteroid administration were associated with a higher incidence of impaired fasting glucose. A case-control study found a slight association between oral glucocorticoid prescriptions and diagnoses of diabetes. (7) The majority of the patients in this study received low daily doses of glucocorticoids. (7) It is presently unknown whether short-term administration of high-dose corticosteroids is associated with the subsequent development of type 2 diabetes, defined as hemoglobin A1c (HbA1c) ≥ 6.5% (48 mmol/mol). (8-9) In addition, no studies have evaluated whether the development of hyperglycemia during the time of short-term, high-dose corticosteroid administration is predictive of type 2 diabetes in the future.","PeriodicalId":15502,"journal":{"name":"Journal of Contemporary Pharmacy Practice","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43964370","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0