在美国社区居住的老年人中,睡眠药物与跌倒和跌倒相关担忧之间的关系

Kathy Nguyen, J. Watanabe
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引用次数: 2

摘要

背景:跌倒是老年人意外致命和非致命伤害的主要原因。睡眠药物与老年人不良事件风险相关。本研究的目的是通过一个具有全国代表性的样本,量化美国65岁及以上成年人中不同程度的睡眠药物使用与跌倒和跌倒相关担忧之间的关系。方法使用2011年全国健康与老龄化趋势研究,采用调查加权多元逻辑回归来确定报告睡眠药物使用的参与者与结果之间的关系:上个月跌倒,去年跌倒,去年多次跌倒,跌倒相关担忧,以及因跌倒相关担忧而限制活动。结果在调整分析中,每晚使用睡眠药物的老年人在过去一年中跌倒的几率比不使用睡眠药物的老年人高,比值比(OR)为1.51(95%可信区间[CL] 1.27, 1.78),多次跌倒的比值比(OR)为1.67(95%可信区间[CL] 1.35, 2.06)。与不服用睡眠药物的人相比,每晚服用睡眠药物的人摔倒的几率没有统计学上的显著增加。大多数晚上(每周5-6个晚上)和每天晚上使用睡眠药物的老年人与不使用睡眠药物的人相比,有跌倒相关担忧的几率增加,OR分别为1.61 (95% CL 1.06, 2.45)和1.32 (95% CL 1.11, 1.58)。结论:每晚服用睡眠药物的老年人摔倒的几率更大,并有跌倒相关的担忧。增加药剂师在社区环境中的参与和药剂师主导的综合药物审查是减少睡眠药物使用和减少老年人跌倒的努力。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Association Between Sleep Medications and Falls and Fall-related Worries in Community-Dwelling Older Adults in the United States
Background Falls are the leading cause of unintentional fatal and nonfatal injuries in seniors. Sleep medications are associated with adverse events risk in older adults. The objective of this study is to quantify the relationship between different levels of sleep medication use with falls and fall-related worries in United States adults aged 65 years and older using a nationally representative sample. Methods Using the 2011 National Health and Aging Trends Study, survey-weighted multiple logistic regression was used to determine the association between participants who reported sleep medication use and the outcomes: falls in the last month, falls in the last year, multiple falls in the last year, fall-related worries, and limitation of activities due to fall-related worries. Results In adjusted analyses, older adults who used sleep medications every night compared to non-users of sleep medications were at increased odds of falls in the last year with an odds ratio (OR) of 1.51 (95% confidence limit [CL] 1.27, 1.78) and of multiple falls with an OR = 1.67 (95% CL 1.35, 2.06). For those who used sleep medications less than every night compared to non-users, there were no statistically significant increased odds of fall outcomes. Older adults who used sleep medication most nights (5–6 nights per week) and every night compared to non-users had increased odds of having fall-related worries with an OR = 1.61 (95% CL 1.06, 2.45) and an OR = 1.32 (95% CL 1.11, 1.58), respectively. Conclusion Older adults who use sleep medication every night are at greater odds of experiencing falls and having fall-related worries. Increased involvement by pharmacists in the community setting and pharmacist-led comprehensive medication reviews are efforts that may reduce sleep medication use and result in fewer falls in older adults.
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