Journal of Clinical Neuroscience最新文献

{"title":"Letter to the editor: Comment on “Serum brain-derived neurotrophic factor level in patients with disc induced lumbosacral radiculopathy: Relation to pain severity and functional disability”","authors":"Adane Desta Gonemo, Ajay Prakash Pasupulla, Murali Santhoshkumar","doi":"10.1016/j.jocn.2024.110814","DOIUrl":"10.1016/j.jocn.2024.110814","url":null,"abstract":"","PeriodicalId":15487,"journal":{"name":"Journal of Clinical Neuroscience","volume":"129 ","pages":"Article 110814"},"PeriodicalIF":1.9,"publicationDate":"2024-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142096754","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Unforeseen outcomes: Unveiling cyst formation post stereotactic radiosurgery in brain arteriovenous malformations cases","authors":"Sarvesh Goyal ,&nbsp;Kushagra Pandey ,&nbsp;Shweta Kedia ,&nbsp;Leve Joseph Devarajan Sebastian ,&nbsp;Deepak Agrawal","doi":"10.1016/j.jocn.2024.110785","DOIUrl":"10.1016/j.jocn.2024.110785","url":null,"abstract":"<div><h3>Introduction</h3><p>Cyst formation after stereotactic radiosurgery (SRS) for brain arteriovenous malformations (AVMs) is a rare, delayed but important complication. Prompt recognition and appropriate treatment is essential for good outcome.</p></div><div><h3>Methods</h3><p>We analysed our institute’s Gamma knife treatment records from 2008 to 2023 and analysed AVM treated patients by gamma knife radiosurgery (GKRS). Patients with cyst formation and with adequate follow up were identified. Clinical details, management and prognosis of these patients was studied in detail along with prior literature review.</p></div><div><h3>Results</h3><p>A total of 921 AVM patients were treated in the above period and 7 patients were identified with cyst formation. The mean nidus volume was 12.98 ml, the mean radio surgical marginal dose was 23.57 Gy and maximal dose 47.21 Gy. The mean interval gap between SRS and cyst detection was 6.45 years. The mean volume of cyst cavity formed was 47.85 ml. Patients presented either with features of raised intracranial pressure (3) or focal neurological deficits (3) or seizures (1). 3 patients had achieved angiographic nidus obliteration at the time of cyst detection. Treatment was mostly on surgical lines with cyst fenestration(2 patients), excision (3 patients) and emergency decompressive craniectomy (1 patient). 1 patient required additional Ommaya insertion. Conservative management was followed for 1 patient. Residual nidus was treated either by concomitant excision or embolization or redo GKRS.</p><p>Favourable outcome was seen in 6 out of 7 patients (85.71%) post cyst management with symptomatic and radiological improvement whereas 1 patient (14.28%) died due to refractory status epilepticus secondary to malignant cerebral edema.</p></div><div><h3>Conclusion</h3><p>Cyst formation after GKRS for AVM treatment is an often-neglected complication due to its low incidence and often long latency period. Long term follow up of patients is hence necessary for prompt recognition. Diagnostic DSA should be done in all patients with cysts to look for residual nidus. Asymptomatic ones can be followed up conservatively while surgical treatment is required for symptomatic cases. Ventricular diversion like Ommaya or cystoperitoneal shunt may be necessary in some cases. Treatment outcome is usually favourable provided timely detection is done.</p></div>","PeriodicalId":15487,"journal":{"name":"Journal of Clinical Neuroscience","volume":"128 ","pages":"Article 110785"},"PeriodicalIF":1.9,"publicationDate":"2024-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142088531","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Letter to the editor: Comment on “Safety and effectiveness of anticoagulation in the management of acute stroke and transient ischemic attack due to intracranial and extracranial non-occlusive thrombus”","authors":"Adane Desta Gonemo ,&nbsp;Ajay Prakash Pasupulla ,&nbsp;Murali Santhoshkumar","doi":"10.1016/j.jocn.2024.110813","DOIUrl":"10.1016/j.jocn.2024.110813","url":null,"abstract":"","PeriodicalId":15487,"journal":{"name":"Journal of Clinical Neuroscience","volume":"129 ","pages":"Article 110813"},"PeriodicalIF":1.9,"publicationDate":"2024-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142088600","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Risk factors for extended hospital stay following minimally invasive transforaminal lumbar interbody fusion","authors":"Fatima N. Anwar,&nbsp;Andrea M. Roca,&nbsp;Srinath S. Medakkar,&nbsp;Alexandra C. Loya,&nbsp;Ishan Khosla,&nbsp;Kern Singh","doi":"10.1016/j.jocn.2024.110793","DOIUrl":"10.1016/j.jocn.2024.110793","url":null,"abstract":"<div><h3>Background</h3><p>Prior literature has examined predictors of length of stay (LOS) for lumbar fusion broadly, grouping multiple surgical approaches into one sample. Evaluating minimally invasive transforaminal lumbar interbody fusion (MIS-TLIF) specifically can reduce variability introduced by other approaches to effectively identify predictors of LOS. The purpose of this study is to evaluate preoperative predictors of extended LOS in patients undergoing MIS-TLIF.</p></div><div><h3>Methods</h3><p>MIS-TLIF patients were identified from a spine surgeon’s database. Preoperative predictors of LOS, including demographics, comorbidity data, spinal pathology, patient-reported back pain, leg pain, physical function, disability, general physical health, mental health, and depressive burden scores were analyzed. Univariate analysis was performed to identify predictors of LOS ≥ 48 and LOS ≥ 72 h, a multivariate analysis confirmed significance. Eight-hundred-one patients were included.</p></div><div><h3>Results</h3><p>African-American patients were 4.3 times more likely to have a LOS≥48 h compared to Caucasians (p ≤ 0.001). Diagnosis of herniated nucleus pulposus and foraminal stenosis were negative predictors of an LOS ≥ 72 h (p ≤ 0.014, both). Self-identified African American patients were approximately twice as likely to have a LOS ≥ 72 h compared to Caucasians. Preoperative Oswestry Disability Index (ODI) was positively correlated with LOS ≥ 48 h (p = 0.008). Other baseline patient-reported outcomes (PROs) were not predictive of LOS ≥ 48 or 72 h (p &gt; 0.050, all).</p></div><div><h3>Conclusions</h3><p>Further research should explore why different demographic characteristics may be associated with extended postoperative LOS to target interventions toward potential health disparities. Understanding preoperative risk factors can help target increased healthcare costs and improve patient care through tailored interventions and future research.</p></div>","PeriodicalId":15487,"journal":{"name":"Journal of Clinical Neuroscience","volume":"128 ","pages":"Article 110793"},"PeriodicalIF":1.9,"publicationDate":"2024-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142088532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association of chronotype and timing of interferon injection with severity of IFNβ-induced flu-like syndrome in Multiple sclerosis (MS) patients","authors":"Mehdi Maghbooli ,&nbsp;Mobin Karami ,&nbsp;Vahid Mohammadi","doi":"10.1016/j.jocn.2024.110811","DOIUrl":"10.1016/j.jocn.2024.110811","url":null,"abstract":"<div><h3>Background</h3><p>Although Interferon-beta (IFNβ) has long been approved as a disease-modifying therapy (DMT) for Multiple sclerosis (MS), flu-like syndrome (FLS) persists as a common adverse effect of interferon therapy. Given the importance of circadian rhythm in regulating physiological processes, we aimed to assess the relationship between patient’s chronotype and time of interferon injection with FLS score in MS patients receiving IFNβ.</p></div><div><h3>Methods</h3><p>A cross-sectional study was conducted on 118 MS patients who were referred to the clinic of neurology of Zanjan Vali-e-Asr Hospital for interferon injection. The included were invited to complete a morningness-eveningness questionnaire (MEQ) assessing patients’ chronotype. The following data were extracted from patients’ record: age, gender, duration of interferon treatment, type of interferon taken, time of interferon injection (morning/evening), FLS score, MS subtype, and usage of pain killers. All data found were imported and statistically analyzed in SPSS <em>ver</em>.26.</p></div><div><h3>Results</h3><p>According to the patients’ record, 114 (96.6%) patients had experienced post-interferon injection FLS with different severities. Statistical analysis revealed no significant relationship between the patient’s chronotype and FLS score. Nevertheless, the FLS score was significantly higher in those who had evening injections.</p></div><div><h3>Conclusions</h3><p>Time of interferon injection was significantly associated with FLS score, with higher FLS score following evening injection. However, no significant relationship was found between the FLS score and the patient’s chronotype. It is recommended that further studies assessing circadian rhythm using laboratory tests such as melatonin measurement need to be undertaken to investigate the association of circadian rhythm with post-interferon injection FLS.</p></div>","PeriodicalId":15487,"journal":{"name":"Journal of Clinical Neuroscience","volume":"128 ","pages":"Article 110811"},"PeriodicalIF":1.9,"publicationDate":"2024-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142088533","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Zahra TAATI ASIL The first Iranian Woman Neurosurgeon","authors":"Keyvan Mostofi","doi":"10.1016/j.jocn.2024.110809","DOIUrl":"10.1016/j.jocn.2024.110809","url":null,"abstract":"<div><p>It is crucial to promote the role of women in surgery, particularly in the field of neurosurgery, which is still predominantly male-dominated. Without recognition and support, these talented and pioneering women may continue to be overlooked, despite their significant contributions to the field. One such remarkable woman is Professor Zahra Taati Asil, the first female Iranian neurosurgeon. Born in 1954 in Iran, she graduated from medical school in Tehran in 1978 with a degree in General Medicine. After completing her studies at the Medical School of the Melli University in 1983, she became the first female Iranian neurosurgeon and was promoted to assistant professor. She held this position for 14 years and during this time, she operated on numerous war-wounded patients during the Iran-Iraq war. Her exceptional surgical skills earned her the nickname “The Golden Hands Surgeon” at Nirou-y-Entezami Hospital, where she had an impressively low rate of postoperative complications. Despite her professional competence, she was never promoted to associate professor, due to reasons beyond her surgical and academic skills. The dean of the university opposed Zahra’s appointment as an associate professor and told her that if she were to be appointed as a professor, the Ministry of Health would separate men and women. He also warned her that the Islamists would only send women to her. She has retired but remains actively involved in both clinical and academic work.</p></div>","PeriodicalId":15487,"journal":{"name":"Journal of Clinical Neuroscience","volume":"128 ","pages":"Article 110809"},"PeriodicalIF":1.9,"publicationDate":"2024-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142077546","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The tonsillouvular fissure approach to exophytic cavernous malformation in the lateral recess of the fourth ventricle: 2-dimensional operative video","authors":"Nebojsa Lasica ,&nbsp;Djula Djilvesi ,&nbsp;Kara A. Parikh","doi":"10.1016/j.jocn.2024.110782","DOIUrl":"10.1016/j.jocn.2024.110782","url":null,"abstract":"<div><p>Cavernous malformations surrounding the fourth ventricle are challenging lesions to access and treat surgically owing to the complexity and eloquence of adjacent neural tissue <span><span>[1]</span></span> Long-standing practice included tissue transgression through the overlying cerebellar cortical surface of the hemisphere or vermis <span><span>[1]</span></span>, <span><span>[2]</span></span>, <span><span>[3]</span></span>. Using natural corridors such as tonsillobiventral fissure, cerebellomedullary fissure, and tonsillouvular fissure (TUF) offers elegant access to the fourth ventricle, avoiding traversing of neural tissue <span><span>[4]</span></span>, <span><span>[5]</span></span>, <span><span>[6]</span></span>, <span><span>[7]</span></span>.</p><p>A 32-year-old male presented with headache, nausea, vomiting, double vision, and vertigo. Neuroimaging demonstrated a 17-mm diameter cavernous malformation protruding into the left lateral recess of the fourth ventricle. The patient consented for the procedure and underwent a middline suboccipital craniotomy in a prone position. TUF approach was performed by dissecting the arachnoid to the depth of the fissure, and after identifying the tonsillomedullary segment of the posterior inferior cerebellar artery, minimal white matter transgression was used to reach cavernous malformation. Complete removal of the lesion was achieved and confirmed on postoperative imaging. The postoperative course was uneventful.</p><p>TUF approach with manipulation by ipsilateral and contralateral retraction of tonsills allows the widening of the surgical corridor and better exposure of lesions of the lateral recess of the fourth ventricle <span><span>[1]</span></span>. TUF approach is a valuable alternative to transvermian and transcerebellar approaches that minimize the division of neural tissue <span><span>[6]</span></span>. To the best of our knowledge this is the first case describing the TUF approach to exophytic cavernoma presenting in the lateral recess of the fourth ventricle.</p><p>Under our institutional ethical review board regulations, approval was not necessary.</p></div>","PeriodicalId":15487,"journal":{"name":"Journal of Clinical Neuroscience","volume":"128 ","pages":"Article 110782"},"PeriodicalIF":1.9,"publicationDate":"2024-08-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142044758","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of adjunctive middle meningeal artery embolization using embosphere particles versus surgical drainage alone for the treatment of chronic subdural hematoma: A prospective study","authors":"Gahn Duangprasert,&nbsp;Sasikan Sukhor,&nbsp;Raywat Noiphithak ,&nbsp;Dilok Tantongtip","doi":"10.1016/j.jocn.2024.110808","DOIUrl":"10.1016/j.jocn.2024.110808","url":null,"abstract":"<div><h3>Background</h3><p>Middle meningeal artery embolization (MMAE) has emerged as a primary and adjunctive therapy for chronic subdural hematoma (CSDH) in addition to conventional treatment. However, there is a scarcity of data that explicitly compares the effectiveness of adjunctive MMAE to surgical drainage alone (SDA), as well as the use of Embosphere particles. The objective of this study was to assess the safety and efficacy of adjunctive MMAE in the treatment of symptomatic CSDH compared to SDA.</p></div><div><h3>Methods</h3><p>This prospective study included 43 patients with 52 CSDH sides, treated at a single institution between 2022 and 2023. The primary outcome was postoperative hematoma volume at 14, 30, 90, and 180 days after surgical drainage, which was analyzed using the generalized estimating equation. The secondary outcomes were the complications and recurrence/reoperation rate. Adjunctive MMAE was performed within 7 days following the surgery, utilizing Embosphere as the embolic material.</p></div><div><h3>Results</h3><p>The patients were assigned to either the adjunctive MMAE group (n = 20, 26 CSDH sides) or the SDA group (n = 23, 26 CSDH sides). The adjunctive MMAE group demonstrated a more significant reduction in hematoma volume (p = 0.007) and maximal hematoma thickness (p = 0.016) at all follow-up intervals. A trend towards lower recurrence and reoperation rates was observed with adjunctive MMAE; particularly, none of the patients in the adjunctive MMAE group experienced a recurrence of CSDH, compared to 19.2 % in the SDA group (p = 0.051). One procedural-related complication (3.8 %) in the adjunctive MMAE group.</p></div><div><h3>Conclusion</h3><p>Our results suggested that adjunctive MMAE, compared to SDA, may enhance hematoma resolution and reduce the need for reoperation due to recurrence.</p></div>","PeriodicalId":15487,"journal":{"name":"Journal of Clinical Neuroscience","volume":"128 ","pages":"Article 110808"},"PeriodicalIF":1.9,"publicationDate":"2024-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142044757","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pallidopontonigral degeneration: Radiological biomarkers of a rare case report","authors":"Daniella Zanoni ,&nbsp;Nitesh Shekhrajka ,&nbsp;Márcio Luís Duarte ,&nbsp;Leonardo Furtado Freitas","doi":"10.1016/j.jocn.2024.110780","DOIUrl":"10.1016/j.jocn.2024.110780","url":null,"abstract":"","PeriodicalId":15487,"journal":{"name":"Journal of Clinical Neuroscience","volume":"128 ","pages":"Article 110780"},"PeriodicalIF":1.9,"publicationDate":"2024-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142040925","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Letter to the Editor: Comment on “Knowledge levels of stroke among hypertensive and diabetic patients in a tertiary hospital”","authors":"Lavanya Kubendiran,&nbsp;Ramya Rajendiran","doi":"10.1016/j.jocn.2024.110805","DOIUrl":"10.1016/j.jocn.2024.110805","url":null,"abstract":"","PeriodicalId":15487,"journal":{"name":"Journal of Clinical Neuroscience","volume":"128 ","pages":"Article 110805"},"PeriodicalIF":1.9,"publicationDate":"2024-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142017674","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}