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Journal of Clinical Psychopharmacology最新文献

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Long-Standing Akathisia Associated With Long-Acting Injectable Aripiprazole: A Case Report. 长效注射阿立哌唑引起的长期静坐症1例报告。
IF 2.9 3区 医学
Journal of Clinical Psychopharmacology Pub Date : 2025-07-01 Epub Date: 2025-04-04 DOI: 10.1097/JCP.0000000000002006
Kaitlyn Cox, Demetra Pantelis, Julio Cesar Pena, Jennifer Yehl
{"title":"Long-Standing Akathisia Associated With Long-Acting Injectable Aripiprazole: A Case Report.","authors":"Kaitlyn Cox, Demetra Pantelis, Julio Cesar Pena, Jennifer Yehl","doi":"10.1097/JCP.0000000000002006","DOIUrl":"10.1097/JCP.0000000000002006","url":null,"abstract":"","PeriodicalId":15455,"journal":{"name":"Journal of Clinical Psychopharmacology","volume":" ","pages":"399-401"},"PeriodicalIF":2.9,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143780002","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Manic Switch Associated With Primidone in a Patient Treated for Essential Tremor. 一名接受普立米酮治疗的重度震颤患者出现躁狂转换。
IF 2.9 3区 医学
Journal of Clinical Psychopharmacology Pub Date : 2025-07-01 Epub Date: 2025-04-04 DOI: 10.1097/JCP.0000000000002008
Francisca Braga, Raquel Luís Medinas, Bruna Meira, Gonçalo Cotovio, Ricardo Caetano Silva
{"title":"Manic Switch Associated With Primidone in a Patient Treated for Essential Tremor.","authors":"Francisca Braga, Raquel Luís Medinas, Bruna Meira, Gonçalo Cotovio, Ricardo Caetano Silva","doi":"10.1097/JCP.0000000000002008","DOIUrl":"10.1097/JCP.0000000000002008","url":null,"abstract":"","PeriodicalId":15455,"journal":{"name":"Journal of Clinical Psychopharmacology","volume":" ","pages":"391-393"},"PeriodicalIF":2.9,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143779924","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Plasma Clozapine in Treatment Refractory Schizophrenia: What Is the Target Range? 难治性精神分裂症患者的血浆氯氮平：目标范围是什么？
IF 2.9 3区 医学
Journal of Clinical Psychopharmacology Pub Date : 2025-07-01 Epub Date: 2025-04-09 DOI: 10.1097/JCP.0000000000002007
Robert James Flanagan, Stephen John Obee, Alice Hyun Min Kim, Susanna Every-Palmer, Paula Liren Valbuena Sanchez, Lauren Evans, Jonathan Rogers, Suzanne Reeves
{"title":"Plasma Clozapine in Treatment Refractory Schizophrenia: What Is the Target Range?","authors":"Robert James Flanagan, Stephen John Obee, Alice Hyun Min Kim, Susanna Every-Palmer, Paula Liren Valbuena Sanchez, Lauren Evans, Jonathan Rogers, Suzanne Reeves","doi":"10.1097/JCP.0000000000002007","DOIUrl":"10.1097/JCP.0000000000002007","url":null,"abstract":"<p><strong>Background: </strong>In treatment-refractory schizophrenia (TRS), a predose plasma concentration of 0.35 mg L -1 is suggested to ensure an adequate trial of clozapine, but the target range may differ between smokers and nonsmokers.</p><p><strong>Method: </strong>We studied data from a clozapine therapeutic drug monitoring service, 1993-2017, with respect to age, sex, smoking status, clozapine dose, estimated clozapine treatment duration, plasma clozapine and norclozapine concentrations, and reason for the request.</p><p><strong>Results: </strong>There were 35,147 and 88,279 samples from 8882 women and 20,378 men, respectively, for which reasons for the request were specified (26,572 samples, 2 reasons; 6421, 3 or more reasons). More samples were sent for analysis due to suspected adverse drug reactions (ADRs) from women (5.3 vs 4.7%, P  < 0.001). The median minimum duration of clozapine treatment before the suspected reaction was 156 days shorter in nonsmokers than smokers of either sex ( P  < 0.001) and shorter in female than male nonsmokers (189 vs 334 d; P  < 0.01). The differences in median plasma clozapine concentrations between suspected ADR (1869/4149 samples from women/men, respectively), and control (10,627/25,848 samples from women/men, respectively) groups were small, averaging 0.03 mg L -1 ( P  < 0.01), but the median plasma clozapine in the ADR and baseline groups was 0.15 mg L -1 lower in smokers than nonsmokers ( P  < 0.001).</p><p><strong>Implications: </strong>The target ranges associated with response to clozapine and minimal ADRs in TRS may be 0.35-0.45 and 0.50-0.60 mg L -1 in smokers and in nonsmokers, respectively. ADRs may occur earlier in treatment in nonsmokers, particularly in women, who in general have higher predose plasma clozapine concentrations than men.</p>","PeriodicalId":15455,"journal":{"name":"Journal of Clinical Psychopharmacology","volume":" ","pages":"336-344"},"PeriodicalIF":2.9,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143811647","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Reply to Letter From Surekha et al: "Lumateperone for Mixed Features in MDD and Bipolar Depression: Advancing Treatment or Raising New Questions". 回复Surekha等人的来信：“Lumateperone治疗重度抑郁症和双相抑郁症的混合特征：推进治疗或提出新问题”。
IF 2.9 3区 医学
Journal of Clinical Psychopharmacology Pub Date : 2025-07-01 Epub Date: 2025-05-30 DOI: 10.1097/JCP.0000000000002019
Suresh Durgam, Susan G Kozauer, Willie R Earley, Changzheng Chen, Jason Huo, Hassan Lakkis, Stephen Stahl, Roger S McIntyre
{"title":"Reply to Letter From Surekha et al: \"Lumateperone for Mixed Features in MDD and Bipolar Depression: Advancing Treatment or Raising New Questions\".","authors":"Suresh Durgam, Susan G Kozauer, Willie R Earley, Changzheng Chen, Jason Huo, Hassan Lakkis, Stephen Stahl, Roger S McIntyre","doi":"10.1097/JCP.0000000000002019","DOIUrl":"10.1097/JCP.0000000000002019","url":null,"abstract":"","PeriodicalId":15455,"journal":{"name":"Journal of Clinical Psychopharmacology","volume":" ","pages":"409-410"},"PeriodicalIF":2.9,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144181850","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Potential Benefits of Chromium and Selenium Supplementation Across Psychiatric Disorders and Symptoms. 补充铬和硒对精神疾病和症状的潜在益处。
IF 2.9 3区 医学
Journal of Clinical Psychopharmacology Pub Date : 2025-07-01 Epub Date: 2025-05-12 DOI: 10.1097/JCP.0000000000002014
Alessandro Di Lisi, Asia Dalla Valle, Marco Menchetti, Concetta Crisafulli, Chiara Fabbri
{"title":"The Potential Benefits of Chromium and Selenium Supplementation Across Psychiatric Disorders and Symptoms.","authors":"Alessandro Di Lisi, Asia Dalla Valle, Marco Menchetti, Concetta Crisafulli, Chiara Fabbri","doi":"10.1097/JCP.0000000000002014","DOIUrl":"10.1097/JCP.0000000000002014","url":null,"abstract":"<p><strong>Background: </strong>The conception of psychiatric disorders as systemic diseases implies an important role of nutrition in mental health. Essential trace elements are present in very small amounts in the body, yet they are essential for many physiological functions.</p><p><strong>Methods: </strong>Little is known about the potential role of chromium and selenium supplementation in mental disorders and other populations. To contribute to filling this gap, this review is focused on the possible benefits of chromium and selenium, alone or in combination with pharmacological treatments, in the treatment of mental disorders or psychiatric symptoms.</p><p><strong>Results: </strong>Chromium and selenium show promising effects on psychiatric symptoms across mental disorders. Selenium may have benefits on anxious-depressive symptoms in healthy populations and groups at risk of nutritional deficits and psychiatric symptoms, for example, women in the post-partum. In addition, chromium was linked to improved insulin sensitivity and glucose metabolism, which can benefit not only metabolic health but also mood regulation, with specific benefits on atypical symptoms of depression, such as appetite/weight gain. Selenium plays a role in reducing oxidative stress and inflammation, which may suggest positive effects on psychopathology and other conditions linked to these mechanisms.</p><p><strong>Conclusions: </strong>Both trace elements may affect positively mental health and cardio-metabolic-inflammatory conditions, which have a strong link with psychiatric disorders and their prognosis. Despite the evidence is not conclusive, chromium and selenium supplementation are interesting options to investigate in future research on the personalization of treatment in mental disorders.</p>","PeriodicalId":15455,"journal":{"name":"Journal of Clinical Psychopharmacology","volume":" ","pages":"376-387"},"PeriodicalIF":2.9,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12184972/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143994736","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Successful Management of Both ADHD and Its Comorbidities With Imipramine Monotherapy. 丙咪嗪单药治疗ADHD及其合并症的成功管理。
IF 2.9 3区 医学
Journal of Clinical Psychopharmacology Pub Date : 2025-07-01 Epub Date: 2025-04-07 DOI: 10.1097/JCP.0000000000002009
Beyza Beyazit, Beyza Nur Karal, Ali Karayağmurlu
{"title":"Successful Management of Both ADHD and Its Comorbidities With Imipramine Monotherapy.","authors":"Beyza Beyazit, Beyza Nur Karal, Ali Karayağmurlu","doi":"10.1097/JCP.0000000000002009","DOIUrl":"10.1097/JCP.0000000000002009","url":null,"abstract":"","PeriodicalId":15455,"journal":{"name":"Journal of Clinical Psychopharmacology","volume":" ","pages":"397-399"},"PeriodicalIF":2.9,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143803380","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Response to "All Patients With Catatonia Deserve Proper Diagnosis, Theragnosis, and Prognosis". 对“所有紧张症患者都应该得到正确的诊断、诊断和预后”的回应。
IF 2.9 3区 医学
Journal of Clinical Psychopharmacology Pub Date : 2025-06-17 DOI: 10.1097/JCP.0000000000002039
Alexandra Rockett, Andrew Stoner, Catherine Ironbar, Joseph Chien
{"title":"Response to \"All Patients With Catatonia Deserve Proper Diagnosis, Theragnosis, and Prognosis\".","authors":"Alexandra Rockett, Andrew Stoner, Catherine Ironbar, Joseph Chien","doi":"10.1097/JCP.0000000000002039","DOIUrl":"https://doi.org/10.1097/JCP.0000000000002039","url":null,"abstract":"","PeriodicalId":15455,"journal":{"name":"Journal of Clinical Psychopharmacology","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144317009","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Under-Eye Bruising Associated With Risperidone in an Adolescent Girl: A Case Report. 青春期女孩使用利培酮引起的眼下瘀伤1例报告。
IF 2.9 3区 医学
Journal of Clinical Psychopharmacology Pub Date : 2025-06-17 DOI: 10.1097/JCP.0000000000002037
Ecem İnce Arslan
{"title":"Under-Eye Bruising Associated With Risperidone in an Adolescent Girl: A Case Report.","authors":"Ecem İnce Arslan","doi":"10.1097/JCP.0000000000002037","DOIUrl":"https://doi.org/10.1097/JCP.0000000000002037","url":null,"abstract":"","PeriodicalId":15455,"journal":{"name":"Journal of Clinical Psychopharmacology","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144317010","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Aripiprazole-Related Acute Myopia: A Case Report. 阿立哌唑相关急性近视1例。
IF 2.9 3区 医学
Journal of Clinical Psychopharmacology Pub Date : 2025-06-13 DOI: 10.1097/JCP.0000000000002036
Gökçe Kavak Sinanoğlu, Fuat Yavrum
{"title":"Aripiprazole-Related Acute Myopia: A Case Report.","authors":"Gökçe Kavak Sinanoğlu, Fuat Yavrum","doi":"10.1097/JCP.0000000000002036","DOIUrl":"https://doi.org/10.1097/JCP.0000000000002036","url":null,"abstract":"","PeriodicalId":15455,"journal":{"name":"Journal of Clinical Psychopharmacology","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144284471","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Tramadol Withdrawal Delirium: A Case Report. 曲马多戒断性谵妄1例报告。
IF 2.9 3区 医学
Journal of Clinical Psychopharmacology Pub Date : 2025-06-13 DOI: 10.1097/JCP.0000000000002041
Vasu Mishra, Swati Choudhary, Navratan Suthar
{"title":"Tramadol Withdrawal Delirium: A Case Report.","authors":"Vasu Mishra, Swati Choudhary, Navratan Suthar","doi":"10.1097/JCP.0000000000002041","DOIUrl":"https://doi.org/10.1097/JCP.0000000000002041","url":null,"abstract":"","PeriodicalId":15455,"journal":{"name":"Journal of Clinical Psychopharmacology","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2025-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144284475","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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