{"title":"Under-Eye Bruising Associated With Risperidone in an Adolescent Girl: A Case Report.","authors":"Ecem İnce Arslan","doi":"10.1097/JCP.0000000000002037","DOIUrl":"10.1097/JCP.0000000000002037","url":null,"abstract":"","PeriodicalId":15455,"journal":{"name":"Journal of Clinical Psychopharmacology","volume":" ","pages":"518-520"},"PeriodicalIF":2.8,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144317010","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Reply to \"Xanomeline/Trospium Combination: Not Non-dopaminergic but a Novel Antidopaminergic Treatment for Schizophrenia\".","authors":"Donald C Goff","doi":"10.1097/JCP.0000000000002029","DOIUrl":"10.1097/JCP.0000000000002029","url":null,"abstract":"","PeriodicalId":15455,"journal":{"name":"Journal of Clinical Psychopharmacology","volume":" ","pages":"530-531"},"PeriodicalIF":2.8,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144821573","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Alexander Panickacheril John, Hitesh Prajapati, Milan Dragovic
{"title":"Metabolic Problems Among People With Treatment-Resistant Schizophrenia are Not Unique to Clozapine.","authors":"Alexander Panickacheril John, Hitesh Prajapati, Milan Dragovic","doi":"10.1097/JCP.0000000000002058","DOIUrl":"10.1097/JCP.0000000000002058","url":null,"abstract":"<p><strong>Background: </strong>It is unclear whether treatment with clozapine, when compared directly with other antipsychotics, is differentially associated with metabolic problems among people with treatment-resistant schizophrenia (TRS). We evaluated the prevalence of diabetes, dyslipidemia, obesity, and hypertension, and parameters such as glucose, lipids, weight, and blood pressure of people with TRS managed on clozapine and non-clozapine antipsychotics.</p><p><strong>Methods: </strong>Demographic, clinical, and metabolic data of patients with TRS who commenced clozapine between 2006 and 2016 at a public hospital were collected in 2023. Participants were divided into those who were on clozapine and those who had discontinued clozapine and were on other antipsychotics when the data were collected. Metabolic disorders of the 2 groups were compared with the t test, the χ 2 test, and the Mann-Whitney U test. The significance level was set at P <0.05.</p><p><strong>Results: </strong>One hundred six participants with TRS were on treatment with clozapine, and 41 with other antipsychotics. The participants' mean age was 44.3 (SD: 10.2) years, and 74.1% were males. Metabolic disorders such as dyslipidemia (45.6%), obesity (37.4%), and diabetes (22.1%) were prevalent among people with TRS. However, there was no significant difference in diabetes, obesity, and hypertension, and parameters such as blood sugar, lipid levels, and blood pressure between the clozapine and non-clozapine cohorts. While dyslipidaemia was significantly higher among those who were managed on clozapine, 75% of them were prescribed statins.</p><p><strong>Conclusions: </strong>A comprehensive approach addressing a broad range of risk factors, rather than solely focusing on clozapine, could be beneficial when evaluating and treating metabolic problems among people with TRS.</p>","PeriodicalId":15455,"journal":{"name":"Journal of Clinical Psychopharmacology","volume":" ","pages":"463-470"},"PeriodicalIF":2.8,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12379792/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144855373","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Detecting Anxious Distress, an Important Mood Specifier.","authors":"Mark J Berber","doi":"10.1097/JCP.0000000000002032","DOIUrl":"10.1097/JCP.0000000000002032","url":null,"abstract":"","PeriodicalId":15455,"journal":{"name":"Journal of Clinical Psychopharmacology","volume":" ","pages":"534-535"},"PeriodicalIF":2.8,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144266363","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Aripiprazole-Related Acute Myopia: A Case Report.","authors":"Gökçe Kavak Sinanoğlu, Fuat Yavrum","doi":"10.1097/JCP.0000000000002036","DOIUrl":"10.1097/JCP.0000000000002036","url":null,"abstract":"","PeriodicalId":15455,"journal":{"name":"Journal of Clinical Psychopharmacology","volume":" ","pages":"520-521"},"PeriodicalIF":2.8,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144284471","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Wangwang Xu, Xinqi Wang, Jingjing Xu, Yang Zhang, Jin Gao
{"title":"Zopiclone Discontinuation-Associated Transient Sleepwalking Behavior: A Case Report.","authors":"Wangwang Xu, Xinqi Wang, Jingjing Xu, Yang Zhang, Jin Gao","doi":"10.1097/JCP.0000000000002045","DOIUrl":"10.1097/JCP.0000000000002045","url":null,"abstract":"","PeriodicalId":15455,"journal":{"name":"Journal of Clinical Psychopharmacology","volume":" ","pages":"521-523"},"PeriodicalIF":2.8,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144731186","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Clonidine and Trihexyphenidyl in Clozapine-induced Hypersalivation.","authors":"Pathum Sookaromdee, Viroj Wiwanitkit","doi":"10.1097/JCP.0000000000002022","DOIUrl":"https://doi.org/10.1097/JCP.0000000000002022","url":null,"abstract":"","PeriodicalId":15455,"journal":{"name":"Journal of Clinical Psychopharmacology","volume":"45 5","pages":"528"},"PeriodicalIF":2.8,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144955880","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}