Journal of critical care最新文献

{"title":"Do weather, season or day of the week affect ICU admissions?","authors":"Mauricio Villavicencio, Juan Garcia-Mendez, Brian Pickering, Daniel Diedrich, Vitaly Herasevich","doi":"10.1016/j.jcrc.2024.154959","DOIUrl":"10.1016/j.jcrc.2024.154959","url":null,"abstract":"","PeriodicalId":15451,"journal":{"name":"Journal of critical care","volume":"86 ","pages":"Article 154959"},"PeriodicalIF":3.2,"publicationDate":"2025-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143508127","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hearing loss assessment by pure tone audiometry amongst the survivors of intensive care unit: A prospective observational cohort study","authors":"Sai Saran ,&nbsp;Abhishek Bahadur Singh ,&nbsp;Avinash Agrawal ,&nbsp;Saumitra Misra ,&nbsp;Suhail Sarwar Siddiqui ,&nbsp;Ayush Lohiya ,&nbsp;Prabhaker Misra","doi":"10.1016/j.jcrc.2025.155042","DOIUrl":"10.1016/j.jcrc.2025.155042","url":null,"abstract":"<div><h3>Purpose</h3><div>To assess hearing deficits (HD) through pure tone audiometry (PTA), amongst the survivors of intensive care unit (ICU).</div></div><div><h3>Methods</h3><div>In this prospective observational study, ICU survivors aged 18 years and above were subjected to PTA and were classified into two groups based on PTA findings as those “with HD” and “without HD”. Demographic and clinical factors were compared between these groups with a <em>p</em>-value of ≤0.05 considered as significant.</div></div><div><h3>Results</h3><div>One hundred and two survivors were enrolled with a median age of 25.5 years (23–30.5), and acute physiology and chronic health evaluation (APACHE II) score of 19 (14–22). Sixty were diagnosed (58.89 %) with HD based on PTA, and forty-two (41.2 %) without HD. More than 80 % of the survivors (52/60) had sensorineural hearing loss (SNHL). Propensity match analysis, after the exact matching of the APACHE-II score between those “with HD” and “without HD”, revealed that patients with HD had a longer duration of shock days (mean ± SD) (0.96 ± 1.24 vs 1.68 ± 1.28; <em>p</em> value: 0.022), received higher maximum noradrenaline dose (0.03 v/s 0.06 μg/kg/min; p value: 0.004), longer duration of endotracheal tube (2.04 ± 1.17 vs 3.52 ± 2.06) days; p value:0.009), more days on mechanical ventilation (2.24 ± 1.33 vs 4.44 ± 5.12; p value: 0.011), and length of stay in the ICU (7.2 ± 3.8 vs 9.24 ± 4.68; p value: 0.013) than those without HD.</div></div><div><h3>Conclusions</h3><div>Hearing deficits are present in majority of the survivors of critical illness and audiometric screening is recommended.</div><div><strong>Trial Registration:</strong> Clinical trials registry. India (CTRI/2022/01/039539) dated 18.01.2022. <span><span>https://ctri.nic.in/Clinicaltrials/login.php</span><svg><path></path></svg></span></div></div>","PeriodicalId":15451,"journal":{"name":"Journal of critical care","volume":"87 ","pages":"Article 155042"},"PeriodicalIF":3.2,"publicationDate":"2025-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143487630","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Point-of-care regional anesthesia in intensive care units: A multi-center professional practice evaluation","authors":"Raïko Blondonnet ,&nbsp;Camille Haumont ,&nbsp;Céline Lambert ,&nbsp;Dominique Morand ,&nbsp;Laurent Zieleskiewicz ,&nbsp;Matthieu Jabaudon ,&nbsp;for the WEEKALR Study Group ,&nbsp;SFAR Research Network","doi":"10.1016/j.jcrc.2025.155029","DOIUrl":"10.1016/j.jcrc.2025.155029","url":null,"abstract":"","PeriodicalId":15451,"journal":{"name":"Journal of critical care","volume":"87 ","pages":"Article 155029"},"PeriodicalIF":3.2,"publicationDate":"2025-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143446097","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Authors reply: “Does extracorporeal cardiopulmonary resuscitation improve survival with favorable neurological outcome in out-of-hospital cardiac arrest? A systematic review and meta-analysis”","authors":"Linda Pagura ,&nbsp;Enrico Fabris ,&nbsp;Serena Rakar ,&nbsp;Marco Gabrielli ,&nbsp;Enzo Mazzaro ,&nbsp;Gianfranco Sinagra ,&nbsp;Davide Stolfo","doi":"10.1016/j.jcrc.2025.155037","DOIUrl":"10.1016/j.jcrc.2025.155037","url":null,"abstract":"","PeriodicalId":15451,"journal":{"name":"Journal of critical care","volume":"87 ","pages":"Article 155037"},"PeriodicalIF":3.2,"publicationDate":"2025-02-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143421818","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Multisystem hemodynamic effects of terlipressin in cirrhosis: A scoping review","authors":"Jeremy Skvarce ,&nbsp;Albert Bui ,&nbsp;Peter Oro ,&nbsp;Saloni Sachar ,&nbsp;Mary Pat Harnegie ,&nbsp;Aanchal Kapoor ,&nbsp;Christina C. Lindenmeyer ,&nbsp;Matthew T. Siuba","doi":"10.1016/j.jcrc.2025.155038","DOIUrl":"10.1016/j.jcrc.2025.155038","url":null,"abstract":"<div><h3>Introduction</h3><div>Hepatorenal syndrome (HRS-AKI) is a serious complication of advanced liver disease. Pharmacologic options are limited in effectiveness, therefore liver transplantation is the definitive therapy. Early investigation into terlipressin as a first-line therapy for HRS-AKI has been promising but expected hemodynamic changes across organ systems in patients with cirrhosis have not been thoroughly examined.</div></div><div><h3>Methods</h3><div>We conducted a scoping review of the literature including adult patients with cirrhosis who received terlipressin and hemodynamic parameters were recorded. Non-human studies, case reports, conference abstracts, and review articles were excluded. Searches were performed up to December 2024 in the following databases: MEDLINE, Embase, Cochrane Library, Scopus, Web of Science, and CINAHL.</div></div><div><h3>Results</h3><div>Of 2022 studies retrieved, 56 studies met inclusion criteria. Heart rate, mean arterial pressure, and cardiac output were the most reported parameters. Pulmonary arterial pressure and wedge pressure were the next most common. Systemic vascular resistance, hepatic and renal measures such as resistive indices and portal pressure gradients had fewer studies. Studies reported decreased heart rate, increased mean arterial pressure, decreased cardiac output/index, and increased systemic vascular resistance. Other hemodynamic outcomes were more varied across studies.</div></div><div><h3>Conclusions</h3><div>Terlipressin exerts a variety of hemodynamic effects across organ systems and vascular beds. More studies are required to understand if any hemodynamic parameters might predict terlipressin response or adverse events.</div></div>","PeriodicalId":15451,"journal":{"name":"Journal of critical care","volume":"87 ","pages":"Article 155038"},"PeriodicalIF":3.2,"publicationDate":"2025-02-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143421242","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Generalization of regional citrate anticoagulation for continuous renal replacement therapy is not associated with an increased rate of severe complications","authors":"Doreen Bachmann ,&nbsp;Céline Monard ,&nbsp;Tatiana Kelevina ,&nbsp;Yannis Ahmad ,&nbsp;Menno Pruijm ,&nbsp;Jean-Daniel Chiche ,&nbsp;Antoine Guillaume Schneider","doi":"10.1016/j.jcrc.2025.155032","DOIUrl":"10.1016/j.jcrc.2025.155032","url":null,"abstract":"<div><h3>Background</h3><div>Contraindications to regional citrate anticoagulation (RCA) for continuous renal replacement therapy (CRRT) have recently been challenged. We aimed to assess the safety of the generalization of RCA to all CRRT sessions.</div></div><div><h3>Methods</h3><div>We reviewed all CRRT sessions performed in our ICU during two periods (P1:2018–2019 and P2:2020–2022). RCA was considered as contraindicated in situations at risk of citrate accumulation (lactate &gt;4 mmol/L and/or prothrombin time &lt; 40 %) during P1 but not P2. We reviewed CRRT modality, filter lifespan, and therapy-associated complications including citrate accumulation, electrolyte and acid/base disturbances, and blood transfusion requirements. CRRT efficacy was assessed by serum creatinine and urea kinetics across circuits' lifespan.</div></div><div><h3>Results</h3><div>We studied 1877 circuits in 467 (P1:245, P2:222) patients. The proportion of patients with risk factors for citrate accumulation was similar between both periods (P1:35 %, P2:32 % <em>p</em> = 0.61). During P2, RCA was used in more circuits (93 vs 66 %, <em>p</em> &lt; 0.001) and filter lifespan was longer (44 vs 32 h, p &lt; 0.001). CRRT efficacy was similar between the two periods. Although risk factors for citrate accumulation were present at first circuit initiation in more RCA circuits during P2 (25 vs 11 %, <em>p</em> = 0.002), the rate of citrate accumulation remained similar (0.3 vs 0.4 %, <em>p</em> = 0.72). There was no increase in the rates of electrolyte disturbances or significant bleeding. There was, however, a higher rate of metabolic acidoses during P2 (13 vs. 9 %, <em>p</em> = 0.01).</div></div><div><h3>Conclusion</h3><div>In an experienced team, generalization of RCA to nearly all patients requiring CRRT extended median filter lifespan without increasing the rate of significant complications.</div></div>","PeriodicalId":15451,"journal":{"name":"Journal of critical care","volume":"87 ","pages":"Article 155032"},"PeriodicalIF":3.2,"publicationDate":"2025-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143421241","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Letter to the editor: “Does extracorporeal cardiopulmonary resuscitation improve survival with favorable neurological outcome in out-of-hospital cardiac arrest? A systematic review and meta-analysis”","authors":"Ahmad Neyazi ,&nbsp;Rachana Mehta ,&nbsp;Shubham Kumar ,&nbsp;Ranjana Sah","doi":"10.1016/j.jcrc.2025.155036","DOIUrl":"10.1016/j.jcrc.2025.155036","url":null,"abstract":"","PeriodicalId":15451,"journal":{"name":"Journal of critical care","volume":"87 ","pages":"Article 155036"},"PeriodicalIF":3.2,"publicationDate":"2025-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143387241","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"What every intensivist should know about ciprofol","authors":"Konica Chittoria ,&nbsp;Arun Mukesh ,&nbsp;Ankur Sharma ,&nbsp;Shilpa Goyal ,&nbsp;Nikhil Kothari","doi":"10.1016/j.jcrc.2025.155034","DOIUrl":"10.1016/j.jcrc.2025.155034","url":null,"abstract":"","PeriodicalId":15451,"journal":{"name":"Journal of critical care","volume":"87 ","pages":"Article 155034"},"PeriodicalIF":3.2,"publicationDate":"2025-02-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143350521","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Emergency critical care - life-saving critical care before ICU admission: A consensus statement of a Group of European Experts","authors":"Martin W. Dünser ,&nbsp;Robert Leach ,&nbsp;Mo Al-Haddad ,&nbsp;Raed Arafat ,&nbsp;Tim Baker ,&nbsp;Martin Balik ,&nbsp;Ruth Brown ,&nbsp;Luca Carenzo ,&nbsp;Jim Connolly ,&nbsp;Daniel Dankl ,&nbsp;Christoph Dodt ,&nbsp;Dinis Dos Reis Miranda ,&nbsp;Aristomenis Exadaktylos ,&nbsp;Srdjan Gavrilovic ,&nbsp;Said Hachimi-Idrissi ,&nbsp;Matthias Haenggi ,&nbsp;Frank Hartig ,&nbsp;Harald Herkner ,&nbsp;Michael Joannidis ,&nbsp;Abdo Khoury ,&nbsp;Wilhelm Behringer","doi":"10.1016/j.jcrc.2025.155035","DOIUrl":"10.1016/j.jcrc.2025.155035","url":null,"abstract":"","PeriodicalId":15451,"journal":{"name":"Journal of critical care","volume":"87 ","pages":"Article 155035"},"PeriodicalIF":3.2,"publicationDate":"2025-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143096703","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Electrical impedance tomography to set high pressure in time-controlled adaptive ventilation","authors":"Benjamin Pequignot ,&nbsp;Mickael Lescroart ,&nbsp;Bruno Levy ,&nbsp;Antoine Kimounn ,&nbsp;Matthieu Koszutski","doi":"10.1016/j.jcrc.2025.155033","DOIUrl":"10.1016/j.jcrc.2025.155033","url":null,"abstract":"<div><h3>Introduction</h3><div>TCAV (Time controlled adaptive ventilation), a combination of settings applied to the APRV (airway pressure release ventilation) mode, provides personalized ventilation tailored to the lung condition in ARDS (acute respiratory distress syndrome). The objective was to evaluate whether electrical impedance tomography (EIT) could serve as a tool for guiding P_high level in TCAV for ARDS patients.</div></div><div><h3>Methods</h3><div>Eleven patients with moderate or severe ARDS were enrolled in a prospective single-center study in 2023. Patients were monitored with EIT (PulmoVista 500). P_high trial was conducted from 34 to 18 cmH₂O, with 4-cmH₂O P_high decrements every 5 min. Driving pressure was maintained constant by adjusting T_low. Best EIT-derived-P_high was defined as the pressure at the crossing point between overdistension and collapse curves.</div></div><div><h3>Results</h3><div>C_RS was significantly higher at P_high 18 cmH2O with 43 [32–50] mL/cmH2O than at P_high 34 with 20 mL/cmH2O [14–24], <em>p</em> &lt; 0.005. Highest P_high levels caused significant overdistension in the anterior region and anterior compliance is significantly lower at P_high 34 with 10 [6–11] mL/cmH2O than at P_high 22 cmH2O with 18 [13–25] mL/cmH2O. Best EIT-derived P_high were 18, 22, 26 cmH₂O for four, five and two patients respectively.</div></div><div><h3>Conclusion</h3><div>EIT enabled detection of regional ventilation distribution on TCAV during a decremental P_high trial and thus enabled the determination of a best EIT-derived-P_high through an individualized approach, achieving best compromise between overdistension and collapse. The observed overdistention variability highlights the necessity of P_high level personalization on TCAV.</div></div>","PeriodicalId":15451,"journal":{"name":"Journal of critical care","volume":"87 ","pages":"Article 155033"},"PeriodicalIF":3.2,"publicationDate":"2025-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143140548","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}