Journal of critical care最新文献

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Fluid infusion prior to intubation or anesthesia: A meta-analysis of randomized controlled trials 插管或麻醉前输液:随机对照试验荟萃分析。
IF 3.2 3区 医学
Journal of critical care Pub Date : 2024-07-24 DOI: 10.1016/j.jcrc.2024.154881
Zhenfeng Lu , Jingsheng Guo , Aiping Zhang , Lin Song , Haibin Ni
{"title":"Fluid infusion prior to intubation or anesthesia: A meta-analysis of randomized controlled trials","authors":"Zhenfeng Lu ,&nbsp;Jingsheng Guo ,&nbsp;Aiping Zhang ,&nbsp;Lin Song ,&nbsp;Haibin Ni","doi":"10.1016/j.jcrc.2024.154881","DOIUrl":"10.1016/j.jcrc.2024.154881","url":null,"abstract":"<div><h3>Background</h3><p>The results of current randomized controlled trials (RCTs) vary regarding the effectiveness of rehydration prior to anesthesia induction. Our objective was to determine the effectiveness of pre-induction rehydration in patients undergoing tracheal intubation or surgical procedures.</p></div><div><h3>Methods</h3><p>This meta-analysis followed PRISMA guidelines and was registered in the INPLASY database (registration number: INPLASY2022100099). Two reviewers independently searched PubMed, Embase, The Cochrane Database of Systematic Reviews, and Clinical Trials databases until October 2022, without any restrictions on date. Any randomized controlled trial investigating the administration of intravenous fluids to patients undergoing tracheal intubation or pre-surgical anesthesia induction was considered eligible. Exclusion criteria were applied to exclude certain literature. Data were analyzed using RevMan (5.4.1) software after independent extraction. The primary objective of this study was to determine if intravenous rehydration could reduce the occurrence of hypotensive events and the use of vasoactive drugs following anesthesia induction.</p></div><div><h3>Results</h3><p>This meta-analysis included seven studies with a total of 2850 patients, including 1430 patients who received rehydration and 1420 control patients. Patients who received early rehydration had a lower incidence of hypotensive events compared to those who did not (RR 0.78, 95% CI 0.66–0.92, <em>P</em> = 0.004). No heterogeneity was observed (<em>p</em> = 0.31, I<sup>2</sup> = 16%). However, subgroup analysis showed that rehydration before tracheal intubation did not reduce hypotensive events in critically ill patients (RR 0.99, 95% CI 0.61–1.60, <em>P</em> = 0.96). There were no significant differences in the use of vasoactive medications between the two study groups (RR 0.96, 95% CI 0.80–1.16, <em>P</em> = 0.69). No heterogeneity was observed (<em>p</em> = 0.26, I<sup>2</sup> = 23%). The funnel plot indicated no evidence of publication bias.</p></div><div><h3>Conclusions</h3><p>Pre-induction rehydration can reduce the occurrence of hypotensive events, but only in pre-surgical patients, and does not decrease the use of vasoactive medications.</p></div>","PeriodicalId":15451,"journal":{"name":"Journal of critical care","volume":"84 ","pages":"Article 154881"},"PeriodicalIF":3.2,"publicationDate":"2024-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141759053","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Does extracorporeal cardiopulmonary resuscitation improve survival with favorable neurological outcome in out-of-hospital cardiac arrest? A systematic review and meta-analysis 体外心肺复苏能否提高院外心脏骤停患者的存活率并改善神经系统预后?系统回顾和荟萃分析。
IF 3.2 3区 医学
Journal of critical care Pub Date : 2024-07-24 DOI: 10.1016/j.jcrc.2024.154882
Linda Pagura , Enrico Fabris , Serena Rakar , Marco Gabrielli , Enzo Mazzaro , Gianfranco Sinagra , Davide Stolfo
{"title":"Does extracorporeal cardiopulmonary resuscitation improve survival with favorable neurological outcome in out-of-hospital cardiac arrest? A systematic review and meta-analysis","authors":"Linda Pagura ,&nbsp;Enrico Fabris ,&nbsp;Serena Rakar ,&nbsp;Marco Gabrielli ,&nbsp;Enzo Mazzaro ,&nbsp;Gianfranco Sinagra ,&nbsp;Davide Stolfo","doi":"10.1016/j.jcrc.2024.154882","DOIUrl":"10.1016/j.jcrc.2024.154882","url":null,"abstract":"<div><h3>Purpose</h3><p>Extracorporeal cardiopulmonary resuscitation (<em>E</em>-CPR) may improve survival with favorable neurological outcome in patients with refractory out-of-hospital cardiac arrest (OHCA). Unfortunately, recent results from randomized controlled trials were inconclusive. We performed a meta-analysis to investigate the impact of <em>E</em>-CPR on neurological outcome compared to conventional cardiopulmonary resuscitation (C-CPR).</p></div><div><h3>Methods</h3><p>A systematic research for articles assessing outcomes of adult patients with OHCA either treated with <em>E</em>-CPR or C-CPR up to April 27, 2023 was performed. Primary outcome was survival with favorable neurological outcome at discharge or 30 days. Overall survival was also assessed.</p></div><div><h3>Results</h3><p>Eighteen studies were included. <em>E</em>-CPR was associated with better survival with favorable neurological status at discharge or 30 days (14% vs 7%, OR 2.35, 95% CI 1.61–3.43, <em>I</em><sup><em>2</em></sup> = 80%, <em>p</em> &lt; 0.001, NNT = 17) than C-CPR. Results were consistent if the analysis was restricted to RCTs. Overall survival to discharge or 30 days was also positively affected by treatment with <em>E</em>-CPR (OR = 1.71, 95% CI = 1.18–2.46, <em>I</em><sup><em>2</em></sup> = 81%, <em>p</em> = 0.004, NNT = 11).</p></div><div><h3>Conclusions</h3><p>In this meta-analysis, E-CPR had a positive effect on survival with favorable neurological outcome and, to a smaller extent, on overall mortality in patients with refractory OHCA.</p></div>","PeriodicalId":15451,"journal":{"name":"Journal of critical care","volume":"84 ","pages":"Article 154882"},"PeriodicalIF":3.2,"publicationDate":"2024-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141759052","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
End-tidal carbon dioxide during spontaneous breathing trial to predict extubation failure: A prospective observational study 预测拔管失败的自主呼吸时潮气末二氧化碳试验:前瞻性观察研究
IF 3.2 3区 医学
Journal of critical care Pub Date : 2024-07-19 DOI: 10.1016/j.jcrc.2024.154870
Faten May , Nicolas de Prost , Keyvan Razazi , Guillaume Carteaux , Armand Mekontso Dessap
{"title":"End-tidal carbon dioxide during spontaneous breathing trial to predict extubation failure: A prospective observational study","authors":"Faten May ,&nbsp;Nicolas de Prost ,&nbsp;Keyvan Razazi ,&nbsp;Guillaume Carteaux ,&nbsp;Armand Mekontso Dessap","doi":"10.1016/j.jcrc.2024.154870","DOIUrl":"10.1016/j.jcrc.2024.154870","url":null,"abstract":"<div><p>Despite advances in weaning protocols, extubation failure (EF) is associated with poor outcomes. Many predictors of EF have been proposed, including hypercapnia at the end of the spontaneous breathing test (SBT). However, performing arterial blood gases at the end of SBT is not routinely recommended, whereas end-tidal carbon dioxide (EtCO2) can be routinely monitored during SBT.</p><p>We aimed to evaluate the clinical utility of EtCO2 to predict EF. Patients undergoing planned extubation were eligible. Non-inclusion criteria were tracheostomy and patients extubated after successful T-tube SBT. We recorded clinical data and EtCO2 in 189 patients during a successful one-hour low pressure support SBT.</p><p>EtCO2 measured before successful SBT was lower in patients with EF compared to those with successful extubation (27 [24–29] vs 30 [27–47] mmHg, <em>p</em> = 0.02), while EtCO2 measured at five minutes and at the end of the SBT was not different between the two groups (26 [22–28] vs. 29 [28–49] mmHg, <em>p</em> = 0.06 and 26 [26–29] vs. 29 [27–49] mmHg, <em>p</em> = 0.09, respectively). Variables identified by multivariable analysis as independently associated with EF were acute respiratory failure as the cause of intubation and ineffective cough.</p><p>Our study suggests that recording EtCO2 during successful SBT appears to have limited predictive value for EF.</p></div>","PeriodicalId":15451,"journal":{"name":"Journal of critical care","volume":"84 ","pages":"Article 154870"},"PeriodicalIF":3.2,"publicationDate":"2024-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141729223","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association of second antibiotic dose delays on mortality in patients with septic shock 第二次抗生素剂量延迟与脓毒性休克患者死亡率的关系。
IF 3.2 3区 医学
Journal of critical care Pub Date : 2024-07-18 DOI: 10.1016/j.jcrc.2024.154866
Zenalabdin H. Jabir PharmD, Travis S. Grey PharmD, BCPS, BCCCP, Angela R. Morelli PharmD, BCPS, BCIDP, Brandon D. Nornhold PharmD, Jestin N. Carlson MD, MS, MHA, Diane V. Thompson M.S, Animesh C. Gour MD
{"title":"Association of second antibiotic dose delays on mortality in patients with septic shock","authors":"Zenalabdin H. Jabir PharmD,&nbsp;Travis S. Grey PharmD, BCPS, BCCCP,&nbsp;Angela R. Morelli PharmD, BCPS, BCIDP,&nbsp;Brandon D. Nornhold PharmD,&nbsp;Jestin N. Carlson MD, MS, MHA,&nbsp;Diane V. Thompson M.S,&nbsp;Animesh C. Gour MD","doi":"10.1016/j.jcrc.2024.154866","DOIUrl":"10.1016/j.jcrc.2024.154866","url":null,"abstract":"<div><h3>Objective</h3><p>Determine whether a delay in the administration of the second dose of antibiotics is associated with an increased risk of mortality for patients admitted with septic shock.</p></div><div><h3>Design</h3><p>Retrospective, observational evaluation.</p></div><div><h3>Setting</h3><p>Regional multicenter evaluation including four institutions in western Pennsylvania.</p></div><div><h3>Patients</h3><p>A total of 905 patients were included in this study who met the criteria for septic shock. Patients that did not receive a second dose of antibiotics, were transferred from an outside facility, or expected death within six hours of hospital admission were excluded.</p></div><div><h3>Interventions</h3><p>The frequency of second antibiotic dose administration delay was determined. A delay was defined as a delay greater than or equal to 25% of the antibiotic dosing interval.</p></div><div><h3>Measurements and main results</h3><p>A delay in second antibiotic dose administration was found in 181 (20%) of patients. Patients with a delay in the administration of second dose antibiotics had a higher mortality rate (35%) than patients without a delay (26%) (<em>p</em> =0.018). Patients with and without a delay in the administration of second-dose antibiotics had similar median 28-day vasopressor free days (median = 26.0, IQR = 2.0). Differences in the distribution of the 28-day vasopressor free days between groups resulted in the achievement of statistical significance (Mann-Whitney U = 57,294.5, z = −2.690, <em>p</em> = 0.006). There was no difference in 28-day ventilator-free days between groups. A delay in the administration of second dose antibiotics led to a longer in-hospital length of stay (9 days vs. 7 days; <em>p</em> = 0.022) and a longer ICU length of stay than patients without a delay (5 days vs. 3 days; <em>p</em> = 0.007).</p></div><div><h3>Conclusions</h3><p>Delays in second antibiotic dose administration in septic shock patients were present but lower than previous studies. These delays were associated with increased mortality, increased ICU and hospital length of stay.</p></div>","PeriodicalId":15451,"journal":{"name":"Journal of critical care","volume":"84 ","pages":"Article 154866"},"PeriodicalIF":3.2,"publicationDate":"2024-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0883944124003538/pdfft?md5=208b61c2418aae33e2a924e19172eed6&pid=1-s2.0-S0883944124003538-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141727255","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Authors response: “Major determinants of primary non function from kidney donation after Maastricht II circulatory death: A single center experience” 作者回复:"马斯特里赫特 II 循环死亡后肾脏捐献主要决定因素:一个单一中心的经验"。
IF 3.2 3区 医学
Journal of critical care Pub Date : 2024-07-17 DOI: 10.1016/j.jcrc.2024.154865
Ana Gaspar , Madalena Gama , Gustavo Nobre de Jesus , Sara Querido , Juliana Damas , João Oliveira , Marta Neves , Alice Santana , João Miguel Ribeiro
{"title":"Authors response: “Major determinants of primary non function from kidney donation after Maastricht II circulatory death: A single center experience”","authors":"Ana Gaspar ,&nbsp;Madalena Gama ,&nbsp;Gustavo Nobre de Jesus ,&nbsp;Sara Querido ,&nbsp;Juliana Damas ,&nbsp;João Oliveira ,&nbsp;Marta Neves ,&nbsp;Alice Santana ,&nbsp;João Miguel Ribeiro","doi":"10.1016/j.jcrc.2024.154865","DOIUrl":"10.1016/j.jcrc.2024.154865","url":null,"abstract":"","PeriodicalId":15451,"journal":{"name":"Journal of critical care","volume":"84 ","pages":"Article 154865"},"PeriodicalIF":3.2,"publicationDate":"2024-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0883944124003526/pdfft?md5=53e96969a2be1fd63d160a7dc60c5d7b&pid=1-s2.0-S0883944124003526-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141723670","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association of early changes in arterial carbon dioxide with acute brain injury in adult patients with extracorporeal membrane oxygenation: A ten-year retrospective study in a German tertiary care hospital 使用体外膜氧合的成年患者动脉二氧化碳的早期变化与急性脑损伤的关系:德国一家三级医院的十年回顾性研究
IF 3.2 3区 医学
Journal of critical care Pub Date : 2024-07-17 DOI: 10.1016/j.jcrc.2024.154880
Yuanyuan Yu , Iris Lettow , Kevin Roedl , Dominik Jarczak , Hans Pinnschmidt , Hermann Reichenspurner , Alexander M. Bernhardt , Gerold Söffker , Benedikt Schrage , Markus Haar , Theresa Weber , Daniel Frings , Stefan Kluge , Marlene Fischer
{"title":"Association of early changes in arterial carbon dioxide with acute brain injury in adult patients with extracorporeal membrane oxygenation: A ten-year retrospective study in a German tertiary care hospital","authors":"Yuanyuan Yu ,&nbsp;Iris Lettow ,&nbsp;Kevin Roedl ,&nbsp;Dominik Jarczak ,&nbsp;Hans Pinnschmidt ,&nbsp;Hermann Reichenspurner ,&nbsp;Alexander M. Bernhardt ,&nbsp;Gerold Söffker ,&nbsp;Benedikt Schrage ,&nbsp;Markus Haar ,&nbsp;Theresa Weber ,&nbsp;Daniel Frings ,&nbsp;Stefan Kluge ,&nbsp;Marlene Fischer","doi":"10.1016/j.jcrc.2024.154880","DOIUrl":"10.1016/j.jcrc.2024.154880","url":null,"abstract":"<div><h3>Purpose</h3><p>To assess the association between fluctuations of arterial carbon dioxide early after start of extracorporeal membrane oxygenation (ECMO) with intracranial hemorrhage (ICH) or ischemic stroke (IS).</p></div><div><h3>Materials and methods</h3><p>This single-center retrospective study included patients who required ECMO for circulatory or respiratory failure between January 2011 and April 2021 and for whom a cerebral computed tomography (cCT) scan was available. Multivariable logistic regression models were fitted to evaluate the association between the relative change of arterial carbon dioxide (RelΔPaCO<sub>2</sub>) and ICH, IS or a composite of ICH, IS, and mortality.</p></div><div><h3>Results</h3><p>In 618 patients (venovenous ECMO: <em>n</em> = 295; venoarterial ECMO: <em>n</em> = 323) ICH occurred more frequently in patients with respiratory failure (19.0%) compared with patients with circulatory failure (6.8%). Conversely, the incidence of IS was higher in patients with circulatory failure (19.2%) compared with patients with respiratory failure (4.7%). While patients with ECMO for respiratory failure were more likely to have ICH (OR 3.683 [95% CI: 1.855;7.309], <em>p</em> &lt; 0.001), they had a lower odds for IS (OR 0.360 [95%CI: 0.158;0.820], <em>p</em> = 0.015) compared with patients with circulatory failure. There was no significant association between RelΔPaCO<sub>2</sub> and ICH or IS.</p></div><div><h3>Conclusions</h3><p>Irrespective of the indication for ECMO, we did not find a significant association between the relative change in PaCO<sub>2</sub> early after ECMO initiation and acute brain injury. Aside from early PaCO<sub>2</sub> decline at cannulation, future studies should address fluctuations of PaCO<sub>2</sub> throughout the course of ECMO support and their effect on acute brain injury.</p></div>","PeriodicalId":15451,"journal":{"name":"Journal of critical care","volume":"84 ","pages":"Article 154880"},"PeriodicalIF":3.2,"publicationDate":"2024-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0883944124003678/pdfft?md5=b32dd72422284b72effb654a1962f737&pid=1-s2.0-S0883944124003678-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141637702","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Critical care management of hantavirus cardiopulmonary syndrome. A narrative review 汉坦病毒心肺综合征的重症监护管理。叙述性综述
IF 3.2 3区 医学
Journal of critical care Pub Date : 2024-07-17 DOI: 10.1016/j.jcrc.2024.154867
Rodrigo Ulloa-Morrison , Nicolas Pavez , Esteban Parra , Rene Lopez , Roberto Mondaca , Paula Fernandez , David Kraunik , Claudia Sanhueza , Sebastian Bravo , Matias Germán Cornu , Eduardo Kattan
{"title":"Critical care management of hantavirus cardiopulmonary syndrome. A narrative review","authors":"Rodrigo Ulloa-Morrison ,&nbsp;Nicolas Pavez ,&nbsp;Esteban Parra ,&nbsp;Rene Lopez ,&nbsp;Roberto Mondaca ,&nbsp;Paula Fernandez ,&nbsp;David Kraunik ,&nbsp;Claudia Sanhueza ,&nbsp;Sebastian Bravo ,&nbsp;Matias Germán Cornu ,&nbsp;Eduardo Kattan","doi":"10.1016/j.jcrc.2024.154867","DOIUrl":"10.1016/j.jcrc.2024.154867","url":null,"abstract":"<div><p>Hantaviruses, members of the <em>Bunyaviridae</em> family, can cause two patterns of disease in humans, hantavirus hemorrhagic fever with renal syndrome (HFRS) and cardiopulmonary syndrome (HCPS), being the latter hegemonic on the American continent. <em>Andesvirus</em> is one of the strains that can cause HCPS and is endemic in Chile. Its transmission occurs through direct or indirect contact with infected rodents' urine, saliva, or feces and inhalation of aerosol particles containing the virus. HCPS rapidly evolves into acute but reversible multiorgan dysfunction. The hemodynamic pattern of HCPS is not identical to that of cardiogenic or septic shock, being characterized by hypovolemia, systolic dysfunction, and pulmonary edema secondary to increased permeability. Given the lack of specific effective therapies to treat this viral infection, the focus of treatment lies in the timely provision of intensive care, specifically hemodynamic and respiratory support, which often requires veno-arterial extracorporeal membrane oxygenation (VA-ECMO). This narrative review aims to provide insights into specific ICU management of HCPS based on the available evidence and gathered experience in Chile and South America including perspectives of pathophysiology, organ dysfunction kinetics, timely life support provision, safe patient transportation, and key challenges for the future.</p></div>","PeriodicalId":15451,"journal":{"name":"Journal of critical care","volume":"84 ","pages":"Article 154867"},"PeriodicalIF":3.2,"publicationDate":"2024-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141637703","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Indications, results and consequences of electroencephalography in neurocritical care: A retrospective study 神经重症监护中脑电图的适应症、结果和后果:回顾性研究
IF 3.2 3区 医学
Journal of critical care Pub Date : 2024-07-16 DOI: 10.1016/j.jcrc.2024.154861
Wolmet E. Haksteen MD , Gulsum Z. Nasim MD , Marjolein M. Admiraal PhD , Daan C. Velseboer MD PhD , A. Fleur van Rootselaar MD,PhD , Janneke Horn MD PhD
{"title":"Indications, results and consequences of electroencephalography in neurocritical care: A retrospective study","authors":"Wolmet E. Haksteen MD ,&nbsp;Gulsum Z. Nasim MD ,&nbsp;Marjolein M. Admiraal PhD ,&nbsp;Daan C. Velseboer MD PhD ,&nbsp;A. Fleur van Rootselaar MD,PhD ,&nbsp;Janneke Horn MD PhD","doi":"10.1016/j.jcrc.2024.154861","DOIUrl":"10.1016/j.jcrc.2024.154861","url":null,"abstract":"<div><h3>Purpose</h3><p>Electrocencephalography (EEG) is a tool to assess cerebral cortical activity. We investigated the indications and results of routine EEG recordings in neurocritical care patients and corresponding changes in anti-seizure medication (ASM).</p></div><div><h3>Materials and methods</h3><p>This was a single-center, retrospective cohort study. We included all adult Intensive Care Unit (ICU) patients with severe acute brain injury who received a routine EEG (30–60 min). Indications, background patterns, presence of rhythmic and periodic patterns, seizures, and adjustments in ASM were documented.</p></div><div><h3>Results</h3><p>A total of 109 patients were included. The EEGs were performed primarily to investigate the presence of (non-convulsive) status epilepticus ((NC)SE) and/or seizures. A (slowed) continuous background pattern was present in 94%. Low voltage, burst-suppression and suppressed background patterns were found in six patients (5.5%). Seizures were diagnosed in two patients and (NC)SE was diagnosed in five patients (6.4%). Based on the EEG results, ASM was changed in 47 patients (43%). This encompassed discontinuation of ASM in 27 patients (24.8%) and initiation of ASM in 20 patients (18.3%).</p></div><div><h3>Conclusions</h3><p>All EEGs were performed to investigate the presence of (NC)SE or seizures. A slowed, but continuous background pattern was found in nearly all patients and (NC)SE and seizures were rarely diagnosed. Adjustments in ASM were made in approximately half of the patients.</p></div>","PeriodicalId":15451,"journal":{"name":"Journal of critical care","volume":"84 ","pages":"Article 154861"},"PeriodicalIF":3.2,"publicationDate":"2024-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0883944124003484/pdfft?md5=661be283939510011156d2de1c85dcc7&pid=1-s2.0-S0883944124003484-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141630741","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Letter to the Editor: “Major determinants of primary non function from kidney donation after Maastricht II circulatory death: A single center experience” 致编辑的信:"马斯特里赫特二期循环死亡后肾脏捐献原发性无功能的主要决定因素:一个单一中心的经验"。
IF 3.2 3区 医学
Journal of critical care Pub Date : 2024-07-15 DOI: 10.1016/j.jcrc.2024.154864
Lingxiang Ran , Rui Zhao , Guangmo Hu
{"title":"Letter to the Editor: “Major determinants of primary non function from kidney donation after Maastricht II circulatory death: A single center experience”","authors":"Lingxiang Ran ,&nbsp;Rui Zhao ,&nbsp;Guangmo Hu","doi":"10.1016/j.jcrc.2024.154864","DOIUrl":"10.1016/j.jcrc.2024.154864","url":null,"abstract":"","PeriodicalId":15451,"journal":{"name":"Journal of critical care","volume":"84 ","pages":"Article 154864"},"PeriodicalIF":3.2,"publicationDate":"2024-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141626873","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Establishing consensus on patient- and family-centered care in adult intensive care units: A Delphi survey 在成人重症监护病房建立以患者和家庭为中心的护理共识:德尔菲调查
IF 3.2 3区 医学
Journal of critical care Pub Date : 2024-07-14 DOI: 10.1016/j.jcrc.2024.154859
Søs Bohart MSc. RN , Anne Højager Nielsen RN, PhD (Associate professor) , Jette Led Sørensen MD, PhD, MMEd (Professor) , Anne Sofie Andreasen MD, PhD (Associate professor) , Tina Waldau MD, MPG, PhD , Ann Merete Møller MD (Professor) , Thordis Thomsen RN, PhD (Professor)
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