Journal of critical care最新文献

{"title":"Sepsis prediction on ICU admission: Limits and opportunities for machine learning","authors":"Alexandra Albu , Franziska Holke , Han Cao , Bianka Hahn , Holger A. Lindner , Lars Feuerbach , Verena Schneider-Lindner","doi":"10.1016/j.jcrc.2024.154973","DOIUrl":"10.1016/j.jcrc.2024.154973","url":null,"abstract":"","PeriodicalId":15451,"journal":{"name":"Journal of critical care","volume":"86 ","pages":"Article 154973"},"PeriodicalIF":3.2,"publicationDate":"2025-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143508871","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Optimal timing for renal replacement therapy in critically ill patients using reinforcement learning algorithms","authors":"Lorenz Kapral , Mohammad Mahdi Azarbeik , Richard Weiss , Razvan Bologheanu , Clemens Heitzinger , Oliver Kimberger","doi":"10.1016/j.jcrc.2024.154964","DOIUrl":"10.1016/j.jcrc.2024.154964","url":null,"abstract":"","PeriodicalId":15451,"journal":{"name":"Journal of critical care","volume":"86 ","pages":"Article 154964"},"PeriodicalIF":3.2,"publicationDate":"2025-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143508872","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Temporal clustering of septic patients with acute kidney injury","authors":"Wonsuk Oh , Kullaya Takkavatakarn , Umesh Gidwani , John Oropello , Roopa Kohli-Seth , Girish Nadkarni , Ankit Sakhuja","doi":"10.1016/j.jcrc.2024.154970","DOIUrl":"10.1016/j.jcrc.2024.154970","url":null,"abstract":"","PeriodicalId":15451,"journal":{"name":"Journal of critical care","volume":"86 ","pages":"Article 154970"},"PeriodicalIF":3.2,"publicationDate":"2025-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143508048","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Extending professional military healthcare to defense operations through supportive AI-assistant trained on high quality treatment data","authors":"Andreas J. Wagner , Meyer Jürgen","doi":"10.1016/j.jcrc.2024.154972","DOIUrl":"10.1016/j.jcrc.2024.154972","url":null,"abstract":"","PeriodicalId":15451,"journal":{"name":"Journal of critical care","volume":"86 ","pages":"Article 154972"},"PeriodicalIF":3.2,"publicationDate":"2025-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143508050","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prediction of cardiac arrest in the pediatric cardiac intensive care unit: A time-series machine learning approach","authors":"Jiaying Lu , Stephanie R. Brown , Yuhua Wu , Kejun Dong , Del Bold , Darren Liu , Jocelyn R. Grunwell , Xiao Hu","doi":"10.1016/j.jcrc.2024.154958","DOIUrl":"10.1016/j.jcrc.2024.154958","url":null,"abstract":"","PeriodicalId":15451,"journal":{"name":"Journal of critical care","volume":"86 ","pages":"Article 154958"},"PeriodicalIF":3.2,"publicationDate":"2025-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143508126","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Microcirculation properties of 20 % albumin in sepsis; a randomised controlled trial","authors":"Rachael A.F. Cusack ,&nbsp;Alejandro Rodríguez ,&nbsp;Ben Cantan ,&nbsp;Alexis Garduno ,&nbsp;Elizabeth Connolly ,&nbsp;Gabor Zilahi ,&nbsp;John Davis Coakley ,&nbsp;Ignacio Martin-Loeches","doi":"10.1016/j.jcrc.2025.155039","DOIUrl":"10.1016/j.jcrc.2025.155039","url":null,"abstract":"<div><h3>Introduction</h3><div>Sepsis and septic shock are associated with microcirculatory dysfunction, significantly impacting patient outcomes. This study aimed to evaluate the effects of a 20 % albumin bolus on microcirculation compared to crystalloid resuscitation in fluid-responsive patients <em>(</em><span><span><em>ClinicalTrials.gov</em></span><svg><path></path></svg></span> <em>ID:</em> <span><span><em>NCT05357339</em></span><svg><path></path></svg></span><em>).</em></div></div><div><h3>Methods</h3><div>We conducted a single-centre randomised controlled trial, enrolling 103 patients (Albumin <em>n</em> = 52, Control <em>n</em> = 51). Fluid responsiveness was assessed, and fluid was administered in boluses of 100 ml to clinical effect. Microcirculation was measured using the Side stream Dark Field camera and AVA 4.3 software. Baseline characteristics, macrohaemodynamics, and microcirculation parameters were recorded. Three patients were excluded from analysis.</div></div><div><h3>Results</h3><div>The final cohort comprised 100 patients, 35 (35 %) females with a mean age of 58 years (range: 18–86). The mean APACHE score was 28 (range: 7–45), and the mean SOFA score was 9.4 (range: 1–17). No significant differences in APACHE (26.24 vs. 29.4, <em>p</em> = 0.069) or SOFA (9.08 vs. 9.78, <em>p</em> = 0.32) scores were found for albumin and control group respectively. The albumin group had worse microcirculation at baseline but demonstrated significant improvements in microvascular density and activity at 15 min and 60 min (<em>p</em> &lt; 0.005), while the control group exhibited no significant changes. Additionally, both groups were fluid responsive, with a mean pulse pressure variability of 17 % at admission. There were no significant differences in overall fluid balances, vasopressor days, length of ICU stay, or mortality between groups.</div></div><div><h3>Conclusion</h3><div>This study demonstrates that a 20 % albumin bolus significantly enhances microcirculation in fluid-responsive patients with septic shock. These findings underscore the potential benefits of targeted microcirculation therapy in critically ill patients.</div></div>","PeriodicalId":15451,"journal":{"name":"Journal of critical care","volume":"87 ","pages":"Article 155039"},"PeriodicalIF":3.2,"publicationDate":"2025-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143510155","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Do weather, season or day of the week affect ICU admissions?","authors":"Mauricio Villavicencio,&nbsp;Juan Garcia-Mendez,&nbsp;Brian Pickering,&nbsp;Daniel Diedrich,&nbsp;Vitaly Herasevich","doi":"10.1016/j.jcrc.2024.154959","DOIUrl":"10.1016/j.jcrc.2024.154959","url":null,"abstract":"","PeriodicalId":15451,"journal":{"name":"Journal of critical care","volume":"86 ","pages":"Article 154959"},"PeriodicalIF":3.2,"publicationDate":"2025-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143508127","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hearing loss assessment by pure tone audiometry amongst the survivors of intensive care unit: A prospective observational cohort study","authors":"Sai Saran ,&nbsp;Abhishek Bahadur Singh ,&nbsp;Avinash Agrawal ,&nbsp;Saumitra Misra ,&nbsp;Suhail Sarwar Siddiqui ,&nbsp;Ayush Lohiya ,&nbsp;Prabhaker Misra","doi":"10.1016/j.jcrc.2025.155042","DOIUrl":"10.1016/j.jcrc.2025.155042","url":null,"abstract":"<div><h3>Purpose</h3><div>To assess hearing deficits (HD) through pure tone audiometry (PTA), amongst the survivors of intensive care unit (ICU).</div></div><div><h3>Methods</h3><div>In this prospective observational study, ICU survivors aged 18 years and above were subjected to PTA and were classified into two groups based on PTA findings as those “with HD” and “without HD”. Demographic and clinical factors were compared between these groups with a <em>p</em>-value of ≤0.05 considered as significant.</div></div><div><h3>Results</h3><div>One hundred and two survivors were enrolled with a median age of 25.5 years (23–30.5), and acute physiology and chronic health evaluation (APACHE II) score of 19 (14–22). Sixty were diagnosed (58.89 %) with HD based on PTA, and forty-two (41.2 %) without HD. More than 80 % of the survivors (52/60) had sensorineural hearing loss (SNHL). Propensity match analysis, after the exact matching of the APACHE-II score between those “with HD” and “without HD”, revealed that patients with HD had a longer duration of shock days (mean ± SD) (0.96 ± 1.24 vs 1.68 ± 1.28; <em>p</em> value: 0.022), received higher maximum noradrenaline dose (0.03 v/s 0.06 μg/kg/min; p value: 0.004), longer duration of endotracheal tube (2.04 ± 1.17 vs 3.52 ± 2.06) days; p value:0.009), more days on mechanical ventilation (2.24 ± 1.33 vs 4.44 ± 5.12; p value: 0.011), and length of stay in the ICU (7.2 ± 3.8 vs 9.24 ± 4.68; p value: 0.013) than those without HD.</div></div><div><h3>Conclusions</h3><div>Hearing deficits are present in majority of the survivors of critical illness and audiometric screening is recommended.</div><div><strong>Trial Registration:</strong> Clinical trials registry. India (CTRI/2022/01/039539) dated 18.01.2022. <span><span>https://ctri.nic.in/Clinicaltrials/login.php</span><svg><path></path></svg></span></div></div>","PeriodicalId":15451,"journal":{"name":"Journal of critical care","volume":"87 ","pages":"Article 155042"},"PeriodicalIF":3.2,"publicationDate":"2025-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143487630","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Point-of-care regional anesthesia in intensive care units: A multi-center professional practice evaluation","authors":"Raïko Blondonnet ,&nbsp;Camille Haumont ,&nbsp;Céline Lambert ,&nbsp;Dominique Morand ,&nbsp;Laurent Zieleskiewicz ,&nbsp;Matthieu Jabaudon ,&nbsp;for the WEEKALR Study Group ,&nbsp;SFAR Research Network","doi":"10.1016/j.jcrc.2025.155029","DOIUrl":"10.1016/j.jcrc.2025.155029","url":null,"abstract":"","PeriodicalId":15451,"journal":{"name":"Journal of critical care","volume":"87 ","pages":"Article 155029"},"PeriodicalIF":3.2,"publicationDate":"2025-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143446097","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Authors reply: “Does extracorporeal cardiopulmonary resuscitation improve survival with favorable neurological outcome in out-of-hospital cardiac arrest? A systematic review and meta-analysis”","authors":"Linda Pagura ,&nbsp;Enrico Fabris ,&nbsp;Serena Rakar ,&nbsp;Marco Gabrielli ,&nbsp;Enzo Mazzaro ,&nbsp;Gianfranco Sinagra ,&nbsp;Davide Stolfo","doi":"10.1016/j.jcrc.2025.155037","DOIUrl":"10.1016/j.jcrc.2025.155037","url":null,"abstract":"","PeriodicalId":15451,"journal":{"name":"Journal of critical care","volume":"87 ","pages":"Article 155037"},"PeriodicalIF":3.2,"publicationDate":"2025-02-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143421818","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}