Journal of Cutaneous Pathology最新文献

{"title":"Co-Existence of a Syringocystadenoma Papilliferum and Tubular Apocrine Adenoma in the Absence of a Nevus Sebaceus: A Case Series and Review of the Literature.","authors":"Ailish Hanly, Robert Stavert, Jennifer M McNiff","doi":"10.1111/cup.70230","DOIUrl":"https://doi.org/10.1111/cup.70230","url":null,"abstract":"<p><strong>Background: </strong>Syringocystadenoma papilliferum (SCAP) and tubular apocrine adenoma (TAA)/papillary eccrine adenoma (PEA) are rare, benign sweat gland tumors that most commonly co-occur in the setting of a nevus sebaceus. Some hypothesize that these tumors exist on a spectrum; however, their co-existence without a nevus sebaceus is infrequently reported.</p><p><strong>Methods: </strong>We searched our dermatopathology laboratory database (2001-2006) for cases of co-occurring SCAP and TAA or PEA without an associated nevus sebaceus and performed a PubMed literature review to identify previously published cases. Data were extracted on patient age, gender, anatomic location, and immunohistochemistry findings.</p><p><strong>Results: </strong>Eight cases were identified at our institution, all in female patients (mean age 43 years). Sites included the scalp (n = 4), mons pubis (n = 2), arm (n = 1), and buttock (n = 1). Five of the eight cases tested demonstrated BRAF V600E positivity in both the SCAP and TAA components. The literature review identified 15 publications reporting 38 cases, with similar IHC findings between SCAP and TAA/PEA; no study reported on BRAF findings.</p><p><strong>Conclusions: </strong>We present one of the largest single-institution series of co-existing SCAP and TAA/PEA without nevus sebaceus. The consistent co-occurrence of these tumors and overlapping molecular profiles supports the hypothesis that SCAP and TAA/PEA may exist on a histologic continuum.</p>","PeriodicalId":15407,"journal":{"name":"Journal of Cutaneous Pathology","volume":" ","pages":""},"PeriodicalIF":1.2,"publicationDate":"2026-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149127815","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cross-Reactivity of Treponema pallidum Polyclonal Antibody With Mycobacterium Species.","authors":"A G Zaladonis, S Waseh, F Ali, S Huang, J T Hyde, M Tuluc, J B Lee","doi":"10.1111/cup.70231","DOIUrl":"https://doi.org/10.1111/cup.70231","url":null,"abstract":"<p><strong>Introduction: </strong>Mycobacteria are typically identified using the acid-fast staining technique. Prior reports have observed cross-reactivity of Treponema pallidum immunohistochemistry (IHC) with Mycobacterium species, particularly Mycobacterium leprae. Further characterization of this cross-reactivity is needed across a broader range of Mycobacterium species, including its extent, strength, and quality.</p><p><strong>Materials and methods: </strong>A retrospective review was conducted to identify all cases of mycobacterial infection at a single institution. Cases with available histopathologic slides were included. Cases in which mycobacteria were not identified on histologic examination were excluded. T. pallidum IHC was performed for each case that met inclusion criteria, and staining patterns were recorded.</p><p><strong>Results: </strong>Of the 55 cases of mycobacterial infection identified, a total of 19 cases met the inclusion criteria: 10 cases of M. leprae, 6 cases of M. chelonae, 2 cases of M. tuberculosis, and 1 case of M. avium. IHC for T. pallidum showed cross-reactivity in all 10 M. leprae cases (100%), 3 of 6 M. chelonae cases (50%), 1 of 2 M. tuberculosis cases (50%), and no staining in the single M. avium case. Cases of M. leprae and M. chelonae showed a consistent strong granular and clumped staining pattern.</p><p><strong>Conclusions: </strong>This study demonstrates that T. pallidum IHC can highlight diverse Mycobacterium species, a cross-reactivity that pathologists should recognize to avoid false-positive interpretations. In the appropriate clinical context, this cross-reactivity may be utilized to further support the diagnosis of leprosy, given the consistently strong staining observed with M. leprae.</p>","PeriodicalId":15407,"journal":{"name":"Journal of Cutaneous Pathology","volume":" ","pages":""},"PeriodicalIF":1.2,"publicationDate":"2026-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149110406","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Histopathologic Features of an Attenuated Onychomatricoma: A Novel Variant.","authors":"Archie Spindler, Derek Maas, Erika Koh, Shari R Lipner, Natalia V Chalupczak, Kristen I Lo Sicco, George Jour, Ata S Moshiri, Alexandra Flamm, Michael Occidental, Garrett Desman, Adam I Rubin","doi":"10.1111/cup.70223","DOIUrl":"10.1111/cup.70223","url":null,"abstract":"<p><p>Onychomatricoma (OM) is a rare benign fibroepithelial nail unit tumor that remains frequently underrecognized, with evolving histopathologic criteria. Existing descriptions have largely focused on well-developed lesions, leaving the histopathologic features of smaller, localized lesions poorly characterized. We report an attenuated OM in a 45-year-old woman highlighting subtle but characteristic histopathologic features of OM, including a focal CD34-positive spindle cell population in the superficial submatrical dermis, matrical epithelial papillation, and focal serum-filled cavity formation within the nail plate. Compared with classic OM, these findings were more localized and less architecturally developed, while still retaining key diagnostic features. Improved recognition of these subtle features in attenuated lesions will facilitate earlier diagnosis, reduce misclassification, and refine clinicopathologic criteria for this important nail unit tumor.</p>","PeriodicalId":15407,"journal":{"name":"Journal of Cutaneous Pathology","volume":" ","pages":""},"PeriodicalIF":1.2,"publicationDate":"2026-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149110327","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dermatologic Toxicities Associated With Novel Pan-RAS/RAF Inhibitors","authors":"Lin J. He,&nbsp;Shaymaa Hegazy,&nbsp;Phyu P. Aung,&nbsp;Priyadharsini Nagarajan,&nbsp;Fiorinda Muhaj,&nbsp;Adrienne N. Choksi,&nbsp;Ana M. Ciurea,&nbsp;Kelly C. Nelson,&nbsp;Doina Ivan,&nbsp;Carlos A. Torres- Cabala,&nbsp;Victor G. Prieto,&nbsp;Jonathan L. Curry","doi":"10.1111/cup.70159","DOIUrl":"10.1111/cup.70159","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>The mitogen-activated protein kinase (MAPK) pathway plays a key role in cell-cycle regulation and tumor progression in cancer. Dermatologic toxicities (DTs) to newer pan-RAS (RMC-6236) and pan-RAF (LXH254/naporafenib) inhibitors are emerging. Therefore, knowledge of the morphologic patterns of DTs from pan-RAS/RAF inhibitors will enable quick diagnosis and appropriate management.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>The clinical and histologic features of patients treated with pan-RAS or pan-RAF inhibitors for advanced stage <i>RAS</i> mutated malignancies were retrospectively reviewed.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Associated DTs were identified in eight patients treated with either pan-RAS (<i>n</i> = 4) or pan-RAF (<i>n</i> = 4) plus MEK/ERK inhibitors for <i>RAS</i> mutated tumors (colorectal, lung, pancreatic, thyroid, melanoma). The patients ranged from 37 to 72 years of age. Five patients had initial clinical presentation of an acneiform eruption complicated by ulceration, flaccid vesicles, or diffuse exfoliative erythroderma. Maculopapular eruption, purpuric patches and papules, and eruptive dark nevi were the other clinical presentations. Skin biopsies were primarily inflammatory with histopathologic features of suppurative folliculitis (<i>n</i> = 2), dermal hypersensitivity reaction (<i>n</i> = 2), subcorneal acantholytic dermatosis (<i>n</i> = 1), subcorneal pustules (<i>n</i> = 1), ulcer (<i>n</i> = 1), and eruptive nevi (<i>n</i> = 1).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Treatment with novel pan-RAS/RAF inhibitors exhibits a spectrum of DTs that exhibit some overlap with small molecule inhibitors that target the MAPK pathway.</p>\u0000 </section>\u0000 </div>","PeriodicalId":15407,"journal":{"name":"Journal of Cutaneous Pathology","volume":"53 11","pages":"1042-1050"},"PeriodicalIF":1.2,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/cup.70159","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148163424","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Chronic “Vegetative” Pemphigus Foliaceus: A Novel Histopathologic Variant","authors":"Michelle Chernyak,&nbsp;Erica Baugh,&nbsp;Bonnie A. Lee","doi":"10.1111/cup.70158","DOIUrl":"10.1111/cup.70158","url":null,"abstract":"<div>\u0000 \u0000 <p>Pemphigus foliaceus (PF) is the second most common subtype among the pemphigus disorders, and is typically characterized by superficial, fragile bullae in a seborrheic distribution. We present a unique case of diffuse PF that mostly resolved with standard therapy but left a few recalcitrant thick “vegetative” plaques. While a psoriasiform presentation of pemphigus foliaceus has been reported, our findings may exist on a spectrum; to our knowledge, this is the first report of persistent “vegetative” lesions of PF in an otherwise classic presentation, raising important questions regarding the pathogenesis of this clinical variant.</p>\u0000 </div>","PeriodicalId":15407,"journal":{"name":"Journal of Cutaneous Pathology","volume":"53 11","pages":"1026-1029"},"PeriodicalIF":1.2,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148143647","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Basal Cell Carcinoma With Ductal Differentiation Presenting as a Large Unilocular Cyst on the Abdomen","authors":"Atsushi Naito,&nbsp;Kodai Furuta,&nbsp;Takaya Fukumoto,&nbsp;Takashi Nakano,&nbsp;Hiroshi Tanabe","doi":"10.1111/cup.70157","DOIUrl":"10.1111/cup.70157","url":null,"abstract":"<div>\u0000 \u0000 <p>We report an unusual case of basal cell carcinoma (BCC) with ductal differentiation presenting as a large unilocular cyst on the abdomen of an 83-year-old Japanese man. An initial punch biopsy showed part of the bilayered cyst wall, suggesting a sweat gland neoplasm. However, complete excision revealed a unilocular cyst continuous with underlying basaloid tumor nests showing peripheral palisading, stromal clefting, and partial BerEP4 expression, consistent with BCC. Both the luminal and outer layers of the cyst also showed partial BerEP4 expression. The luminal layer was positive for epithelial membrane antigen (EMA) and carcinoembryonic antigen, indicating that the unilocular cyst was a genuine cyst rather than a pseudocyst secondary to mucin deposition or tumor necrosis. The outer layer lacked myoepithelial markers including SRY-box transcription factor 10 and smooth muscle actin, suggesting that it represented part of the BCC rather than myoepithelium. Overall, we diagnosed the lesion as BCC with ductal differentiation forming a cyst with an EMA-positive lining. BCC with ductal differentiation has been reported, but cases with large unilocular cysts are uncommon. This case broadens the histologic spectrum of BCC and emphasizes the importance of complete excision and comprehensive immunohistochemical analysis in cystic lesions to avoid misdiagnosis.</p>\u0000 </div>","PeriodicalId":15407,"journal":{"name":"Journal of Cutaneous Pathology","volume":"53 11","pages":"1021-1025"},"PeriodicalIF":1.2,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148054732","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Discoid Lupus Erythematosus in Genital Skin: A Case Report and Review of the Literature","authors":"Ala' Abu-Dayeh,&nbsp;Daniel Miller,&nbsp;Alessio Giubellino","doi":"10.1111/cup.70145","DOIUrl":"10.1111/cup.70145","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Discoid lupus erythematosus (DLE) represents the most common variant of chronic cutaneous lupus erythematosus, a skin-specific autoimmune disorder within the broader lupus erythematosus spectrum Clinically, DLE is characterized by erythematous, scaly plaques with areas of hyperpigmentation. These lesions predominantly occur on sun-exposed areas, particularly the scalp and cheeks. Involvement of the genital skin is rare and poses a significant diagnostic challenge due to its clinical overlap with other inflammatory and infectious dermatoses. To date, only 14 cases involving genital skin have been documented in the literature, with most described in female patients and a particular tendency for the vulva to be affected.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Case Presentation</h3>\u0000 \u0000 <p>We present the case of a 60-year-old female with a past medical history of systemic sclerosis and Raynaud's syndrome, who presented with well-demarcated, erythematous, keratotic plaques with atrophy involving the inguinal creases and medial buttocks, associated with pruritus and recent onset of pain when sitting. The rash had been present for years. Clinical differential diagnoses included lichen sclerosus, lichen simplex chronicus, and psoriasis. Histopathologic examination revealed orthokeratosis and parakeratosis, epidermal hyperplasia, thickened basement membrane, dilated blood vessels, and perivascular inflammation. Plasmacytoid dendritic cells were present in the dermis and highlighted by CD123 immunohistochemical stain, supporting the diagnosis of DLE. Systemic evaluation was negative for systemic lupus erythematosus. The patient was started on treatment with topical corticosteroids.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>This case highlights the importance of including DLE in the differential diagnosis of chronic genital dermatoses and reinforces the value of histopathologic evaluation in such cases.</p>\u0000 </section>\u0000 </div>","PeriodicalId":15407,"journal":{"name":"Journal of Cutaneous Pathology","volume":"53 11","pages":"1000-1006"},"PeriodicalIF":1.2,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/cup.70145","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147982046","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Transverse Histological Analysis of Scalp Seborrheic Dermatitis: A Novel Perspective","authors":"Tatiane Elen de Souza,&nbsp;Almut Böer-Auer,&nbsp;Betina Werner","doi":"10.1111/cup.70147","DOIUrl":"10.1111/cup.70147","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Seborrheic dermatitis is a chronic inflammatory disease affecting seborrheic areas of the skin, including the scalp. It is often confused with scalp psoriasis due to similar clinical and histopathological features.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>This study described microscopic changes in the pilosebaceous unit in seborrheic dermatitis (SDS) using cross-sectional histological sections in order to improve diagnostic accuracy in differentiating SDS from scalp psoriasis and early-stage alopecia.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>This study included 35 men aged 18–65 diagnosed with SDS (both mild and severe cases). Scalp biopsies were obtained and analyzed for 35 microscopic parameters, including quantitative and qualitative variables, and compared with the data of scalp psoriasis from a previous study.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Among 35 scalp biopsies from seborrheic dermatitis (SDS) cases, no significant histological differences were observed between mild and severe forms. Sebaceous gland atrophy was absent in SDS but present in 40% of 22 psoriasis cases, which also showed significantly smaller gland size (0.22 vs. 0.51 mm; <i>p</i> &lt; 0.05). Perifollicular inflammation and fibrosis were common in SDS, while Malassezia yeasts and Demodex mites were rarely identified.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Limitations</h3>\u0000 \u0000 <p>The small sample size and lack of longitudinal follow-up limit the generalizability of the results. Additionally, only scalp biopsies were analyzed, excluding other affected areas.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>The findings emphasize that the absence of sebaceous gland atrophy is a useful criterion in the differentiation of seborrheic dermatitis from psoriasis of the scalp. They also highlight the diagnostic complexity of SDS with histological features that could be confused with some scarring alopecias, especially fibrosing alopecia in a pattern distribution.</p>\u0000 </section>\u0000 </div>","PeriodicalId":15407,"journal":{"name":"Journal of Cutaneous Pathology","volume":"53 11","pages":"1055-1061"},"PeriodicalIF":1.2,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/cup.70147","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148030915","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluating Large Language Models for Melanocytic Lesion Pathology Report Interpretation","authors":"Sasha Severin,&nbsp;Mehdi Boostani,&nbsp;Lana Salloum,&nbsp;Szabolcs Bozsanyi,&nbsp;Zahidul Islam,&nbsp;Wendy Huss,&nbsp;Joshua Arbesman,&nbsp;Alicia Goldenberg,&nbsp;Gyorgy Paragh","doi":"10.1111/cup.70121","DOIUrl":"10.1111/cup.70121","url":null,"abstract":"","PeriodicalId":15407,"journal":{"name":"Journal of Cutaneous Pathology","volume":"53 11","pages":"982-985"},"PeriodicalIF":1.2,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148329879","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Merkel Cell Carcinoma With Divergent Differentiation—Or Something Else? A Triphasic Cutaneous Carcinoma With Lineage Plasticity","authors":"Zeinab Khalil,&nbsp;Hozaifa Elameen,&nbsp;Ahmed K. Alomari","doi":"10.1111/cup.70144","DOIUrl":"10.1111/cup.70144","url":null,"abstract":"<p>Merkel cell carcinoma (MCC) is a rare, aggressive cutaneous neuroendocrine carcinoma that typically arises in sun-exposed skin of older or immunosuppressed patients. Combined or collision tumors involving MCC and other cutaneous malignancies are uncommon, and tumors exhibiting more than two distinct malignant phenotypes are exceptionally rare. We report a case of a triphenotypic carcinoma in the left upper arm composed of a neuroendocrine carcinoma with Merkel cell features, a poorly differentiated carcinoma with squamous/ductal differentiation, and a sarcomatoid component, each demonstrating distinct morphologic and immunophenotypic profiles. While the findings favor classification as MCC with divergent epithelial and sarcomatoid differentiation, the precise lineage and cell of origin cannot be definitively established, and alternative interpretations are considered and discussed. This unusual case highlights the diagnostic challenge posed by plastic cutaneous carcinomas and underscores the importance of comprehensive histologic evaluation, broad immunohistochemical workup, and multidisciplinary management. We review the relevant literature of cases with comparable histomorphology and discuss the implications for diagnosis, staging, and treatment.</p>","PeriodicalId":15407,"journal":{"name":"Journal of Cutaneous Pathology","volume":"53 11","pages":"994-999"},"PeriodicalIF":1.2,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/cup.70144","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147972883","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}