Journal of Cutaneous Medicine and Surgery最新文献_第2页

Characteristics, Management, and Outcomes of Cutaneous Malignancies Arising From Necrobiosis Lipoidica: A Systematic Review. 脂质坏死症引起的皮肤恶性肿瘤的特征、处理和结果：一项系统综述。

IF 3.1 4区医学

Journal of Cutaneous Medicine and Surgery Pub Date : 2025-06-19 DOI: 10.1177/12034754251351637

Darshana Seeburruth, Siddhartha Sood, Martin Heung, Ilya Mukovozov

引用次数: 0

Efficacy of Antipsychotic Treatment for Delusional Infestation: A Retrospective Cohort Study. 抗精神病药物治疗妄想感染的疗效：一项回顾性队列研究。

IF 3.1 4区医学

Journal of Cutaneous Medicine and Surgery Pub Date : 2025-06-19 DOI: 10.1177/12034754251345785

Erman Şentürk, Burak Erman Menkü, Peter Lepping, Behcet Coşar

{"title":"Efficacy of Antipsychotic Treatment for Delusional Infestation: A Retrospective Cohort Study.","authors":"Erman Şentürk, Burak Erman Menkü, Peter Lepping, Behcet Coşar","doi":"10.1177/12034754251345785","DOIUrl":"10.1177/12034754251345785","url":null,"abstract":"Background: Delusional infestation (DI) is a rare psychiatric disorder characterized by false beliefs in infestation, often presenting to dermatology clinics with unexplained skin complaints. Antipsychotic treatments are commonly used; however, their comparative efficacy in DI remains unclear.Objective: This study aimed to evaluate the comparative efficacy of six antipsychotics-pimozide, olanzapine, aripiprazole, risperidone, amisulpride, and paliperidone-in the treatment of DI.Methods: A retrospective observational cohort study was conducted at a university hospital in Turkey, analyzing anonymized medical records from 36 patients diagnosed with DI and treated with one of six antipsychotics between 2014 and 2023. Equivalent doses of antipsychotics were standardized to 100 mg of chlorpromazine. Clinical Global Impression Severity (CGI-S) scores were used to assess treatment response at baseline, 3 months, and 6 months. Repeated measures ANOVA was employed to compare the efficacy of each antipsychotic over time.Results: All six antipsychotics significantly reduced CGI-S scores over the 6-month period (P < 0.001). Amisulpride, followed by paliperdione and risperidone, demonstrated the most substantial improvements, with mean CGI-S scores decreasing from 5.43 to 1.71, 5.20 to 2.00, and 5.17 to 2.00, respectively, by 6 months. Pimozide showed reasonable efficacy. Aripiprazole and olanzapine had the least efficacy after 6 months. There was a significant reduction over time in aripiprazole showing the strongest initial response.Conclusions: Amisulpride, followed by paliperidone and risperidone, emerged as the most effective treatments for DI, with the greatest reductions in symptom severity, confirming previous studies. The effect is significant over time.","PeriodicalId":15403,"journal":{"name":"Journal of Cutaneous Medicine and Surgery","volume":" ","pages":"12034754251345785"},"PeriodicalIF":3.1,"publicationDate":"2025-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144333162","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Nemolizumab for the Treatment of Dermatological Conditions: A Systematic Review of Randomized Placebo-Controlled Trials. 奈莫单抗治疗皮肤病：随机安慰剂对照试验的系统评价。

IF 3.1 4区医学

Journal of Cutaneous Medicine and Surgery Pub Date : 2025-06-19 DOI: 10.1177/12034754251351620

Jia Qi Adam Bai, Ryan S Q Geng, Sana Gupta, Edgar Akuffo-Addo, Megan Lam, Cathryn Sibbald

引用次数: 0

A Scoping Review of Pruritic Papular Eruption in People Living With HIV. HIV感染者瘙痒性丘疹的范围综述。

IF 3.1 4区医学

Journal of Cutaneous Medicine and Surgery Pub Date : 2025-06-17 DOI: 10.1177/12034754251349192

Vincent Pecora, Yagiz Matthew Akiska, Adam Friedman

{"title":"A Scoping Review of Pruritic Papular Eruption in People Living With HIV.","authors":"Vincent Pecora, Yagiz Matthew Akiska, Adam Friedman","doi":"10.1177/12034754251349192","DOIUrl":"https://doi.org/10.1177/12034754251349192","url":null,"abstract":"Pruritic papular eruption (PPE) is a chronic, intensely itchy skin condition commonly seen in people living with HIV (PLH). While PPE is well documented in regions with high HIV prevalence, its clinical presentation, risk factors, and treatment strategies in the United States remain poorly characterized. Thus, this study aims to fill critical gaps in understanding PPE among PLH in the United States by investigating its epidemiology, clinical features, and risk factors. A comprehensive literature search across PubMed, Google Scholar, and Cochrane identified 8 papers documenting 11 patients with PPE. Our results showed that the most commonly affected areas included the arms (82%), chest (45%), back (45%), face (36%), neck (36%), and anal cleft (18%). Seven patients (64%) had a concurrent bacterial or fungal infection with Candida albicans (42.9%) and Treponema pallidum (42.9%). Candida lesions were most commonly seen in the oral mucosa and inguinal or anal clefts. Overgrowth of commensal organisms such as Demodex folliculorum was also noted in or around the pilosebaceous units for 28.6% of patients. The most common treatment strategies include antiretroviral therapy and adjuvant corticosteroid or ultraviolet B phototherapy which helped relieve the pruritis associated with papulonodular lesions. These findings highlight how PPE may serve as a marker for severe immunosuppression among PLH. In HIV patients who present with a rapid onset of pruritic lesions, PPE should be a key consideration in the differential diagnosis. In these patients, thorough physical examination and further diagnostic evaluation for potentially associated infections is warranted.","PeriodicalId":15403,"journal":{"name":"Journal of Cutaneous Medicine and Surgery","volume":" ","pages":"12034754251349192"},"PeriodicalIF":3.1,"publicationDate":"2025-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144317045","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Advancing Mohs Micrographic Surgery Through Artificial Intelligence: A Provider's Implementation Guide. 通过人工智能推进莫氏显微手术：供应商实施指南。

IF 3.1 4区医学

Journal of Cutaneous Medicine and Surgery Pub Date : 2025-06-17 DOI: 10.1177/12034754251349193

Grace Herrick, Zachary Grand, Kelly Frasier, Alexander Mazzoranna, Ivelina Kioutchoukova, Devon Foster, Christopher Ciesla, Mikaela Rockwell, Erin Lowe

{"title":"Advancing Mohs Micrographic Surgery Through Artificial Intelligence: A Provider's Implementation Guide.","authors":"Grace Herrick, Zachary Grand, Kelly Frasier, Alexander Mazzoranna, Ivelina Kioutchoukova, Devon Foster, Christopher Ciesla, Mikaela Rockwell, Erin Lowe","doi":"10.1177/12034754251349193","DOIUrl":"https://doi.org/10.1177/12034754251349193","url":null,"abstract":"Integrating artificial intelligence (AI) into Mohs micrographic surgery (MMS) represents a transformative advancement in dermatological surgery, with the potential to significantly enhance surgical precision, efficiency, and patient outcomes. This review provides a comprehensive summary of AI's current and emerging roles in MMS, focusing on its application in tumor margin identification, surgical precision, and tissue preservation. Further, it explores AI's role in predicting tumor complexity and postoperative outcomes, emphasizing how these predictive models can be incorporated into personalized care plans and long-term patient monitoring. Practical steps for implementing AI in clinical practice are provided, focusing on the necessary infrastructure, training, and potential barriers to adoption, while considering the financial implications and potential return on investment for providers. Additionally, this review analyzes the ethical and legal considerations surrounding AI use in MMS, discussing data privacy, security, and the legal implications of AI-assisted procedures. The integration of AI in MMS holds immense promise, but its successful adoption will require careful consideration of clinical, ethical, and financial factors to ensure that this technology ultimately benefits both patients and healthcare providers.","PeriodicalId":15403,"journal":{"name":"Journal of Cutaneous Medicine and Surgery","volume":" ","pages":"12034754251349193"},"PeriodicalIF":3.1,"publicationDate":"2025-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144317046","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Characterizing Tofacitinib Response in Pediatric Alopecia Areata: A Retrospective Review. 托法替尼治疗儿童斑秃疗效的回顾性分析。

IF 3.1 4区医学

Journal of Cutaneous Medicine and Surgery Pub Date : 2025-06-16 DOI: 10.1177/12034754251347577

Michal Moshkovich, Cinthiya Sugumar, Cathryn Sibbald

引用次数: 0

Treatment Algorithm Suggestion for Hailey-Hailey Disease. 海莉病的治疗算法建议。

IF 3.1 4区医学

Journal of Cutaneous Medicine and Surgery Pub Date : 2025-06-16 DOI: 10.1177/12034754251344213

Nefeli Giannopoulou, Olivia Mathot, Bertrand Richert

{"title":"Treatment Algorithm Suggestion for Hailey-Hailey Disease.","authors":"Nefeli Giannopoulou, Olivia Mathot, Bertrand Richert","doi":"10.1177/12034754251344213","DOIUrl":"https://doi.org/10.1177/12034754251344213","url":null,"abstract":"Hailey-Hailey disease is a rare genodermatosis, with an autosomal dominant inheritance pattern. Its incidence is estimated at 1/50,000. It is characterized by compromised adhesion between epidermal keratinocytes. It results from a heterozygous mutation in the ATP2C1 gene, causing the diagnostic triad: suprabasal acantholysis, loosely joined keratinocytes, and occasional dyskeratosis. Clinically, it presents between the third and fourth decades as blisters and flaccid vesicles, leading to the development of fissures, erosions, rhagades, and vegetations. Lesions are distributed symmetrically in flexural areas. It has a chronic relapsing course with periods of remission and exacerbation. There is no cure and therapeutic options remain limited. General non-pharmacological measures are crucial. Treatments include topical agents (corticosteroids, calcineurin inhibitors, antibiotics, calcitriol) and systemic agents (antibiotics, anticholinergics, retinoids, apremilast, dapsone, immunosuppressants, biologicals, naltrexone, vitamin D), as well as procedural therapy such as carbon dioxide laser, botulinum toxin, dermabrasion, photodynamic therapy, and surgery. Given the lack of evidence-based guidelines and large clinical trials, evaluating the effectiveness and safety of treatments is challenging. This review presents a systematic analysis of the literature with a focus on both established and emerging treatment options for Hailey-Hailey disease with the aim to provide a therapeutic algorithm. The evidence supporting each treatment option will be assessed, emphasizing the strength of the data to guide clinical decision-making.","PeriodicalId":15403,"journal":{"name":"Journal of Cutaneous Medicine and Surgery","volume":" ","pages":"12034754251344213"},"PeriodicalIF":3.1,"publicationDate":"2025-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144302205","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Adolescent Folliculotropic Mycosis Fungoides. 青春期嗜滤泡性真菌病。

IF 3.1 4区医学

Journal of Cutaneous Medicine and Surgery Pub Date : 2025-06-14 DOI: 10.1177/12034754251347573

Jinhui Xu, Xiuzu Song

引用次数: 0

Shedding Light on Canadian Medico-Legal Cases of Hair Loss Treatment: A Retrospective Review. 加拿大脱发治疗的医学法律案例：回顾性回顾。

IF 3.1 4区医学

Journal of Cutaneous Medicine and Surgery Pub Date : 2025-06-14 DOI: 10.1177/12034754251347560

Eric McMullen, Ammar Saed Aldien, Ilya Mukovozov, James Chu, Laura Payant, Jun Ji, Kimberley Montague, Gary Garber, Jeffrey Donovan

引用次数: 0

The Use of Hormonal Therapies in Patients with Hidradenitis Suppurativa: A Systematic Review. 化脓性汗腺炎患者激素疗法的应用：系统综述。

IF 3.1 4区医学

Journal of Cutaneous Medicine and Surgery Pub Date : 2025-06-14 DOI: 10.1177/12034754251347592

Jonah W Perlmutter, Michal Moshkovich, Rebecca Levy

引用次数: 0