Journal of Computer Assisted Tomography最新文献

{"title":"Varied Symptomatology and Computed Tomography Analysis of Coral Reef Aorta: Exploring the Symptom-location Relationship.","authors":"Hideyuki Torikai, Luke Wilkins, Patrick Norton, John Fritz Angle","doi":"10.1097/RCT.0000000000001777","DOIUrl":"https://doi.org/10.1097/RCT.0000000000001777","url":null,"abstract":"<p><strong>Purpose: </strong>To describe the clinical manifestations of coral reef aorta (CRA), determine the common locations of CRA on CT, and assess the relationship between lesion location and clinical symptoms.</p><p><strong>Materials and methods: </strong>Keyword detection in CT reports at a single institution between 2008 and 2021 revealed 27 patients with CRA. Aortic segments were grouped by relation to the aortic branches. Patient's characteristics, cardiovascular risk factors, treatments, and outcomes were collected from the medical record.</p><p><strong>Results: </strong>Median age was 63.7 (IQR: 58.1-70.6). Of the total, 77.8% (21/27) were females. The most common risk factors were hypertension (23/27) and smoking (24/27). Diabetes was present in 4/27, 14.8%. All CRAs were at the level of the celiac trunk or distal. The most common symptom was claudication (9/27), but 8/27 were asymptomatic. Approximately 74% of the CRAs were superior to the inferior mesenteric artery (20/27).Claudication was significantly more common in patients with CRA inferior to the inferior renal artery (iRA, 8/13, 61.5%) than those with the CRA superior to the iRA (including iRA) (2/14, 14.3%; P = 0.018). Pulmonary edema was seen in 2/5 patients with CRA between the superior renal artery and iRA compared with none when the CRA was located in other segments (P = 0.043).</p><p><strong>Conclusion: </strong>Nearly all patients with CRA had a history of hypertension and smoking, and the majority were female. The most common CRA segment was distal to the iRA, which was associated with claudication. The CRA involving the renal arteries was associated with recurring pulmonary edema.</p>","PeriodicalId":15402,"journal":{"name":"Journal of Computer Assisted Tomography","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2025-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144496833","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Neuroimaging Applications of Photon-counting CT.","authors":"Siddhant Dogra, Ajay Madhavan, Gul Moonis","doi":"10.1097/RCT.0000000000001776","DOIUrl":"https://doi.org/10.1097/RCT.0000000000001776","url":null,"abstract":"<p><p>Photon-counting computed tomography (PCCT) is a new imaging technology that has advanced diagnostic imaging by offering improved spatial and contrast resolution as well as novel spectral imaging capabilities. Unlike conventional CT, which uses energy-integrating detectors, PCCT employs photon-counting detectors that directly measure individual photon energies, enabling applications such as virtual monochromatic imaging (VMI) and material decomposition. These innovations allow for artifact reduction, better visualization of fine anatomic structures, and improved diagnostic accuracy, all while reducing radiation dose. This review explores select applications of PCCT in neuroimaging, focusing on the brain, temporal bone, and spine. In the brain, we discuss how PCCT demonstrates superior performance for evaluating aneurysms, metallic prostheses, and vessel stenosis, offering enhanced visualization of vascular structures and minimizing artifacts. For temporal bone imaging, we review assessment of both complex anatomy and potentially subtle pathologies such as otosclerosis, as well as visualization of implants like cochlear devices and their intricate components. In spinal imaging, we explore how PCCT improves precise detection of causes of cerebrospinal fluid leaks, improves localization of tiny vessels such as the artery of Adamkiewicz and spinal dural arteriovenous fistulas, and reduces metal artifacts associated with postoperative hardware. PCCT addresses limitations of conventional CT while unlocking new diagnostic possibilities across neuroimaging applications. As clinical adoption of PCCT grows, ongoing research and development will refine imaging protocols and expand its utility. The accumulating evidence underscores PCCT's transformative potential to improve diagnostic confidence in neuroimaging and beyond.</p>","PeriodicalId":15402,"journal":{"name":"Journal of Computer Assisted Tomography","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2025-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144496812","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Combining the Qualitative and Quantitative Parameters of Dual-layer Detector Spectral Computed Tomography to Predict Intracranial Hemorrhage in Acute Ischemic Stroke Patients After Mechanical Thrombectomy.","authors":"Manman Cui, Dongliang Hu, Yuanyuan Wu, Yan Liu, Duchang Zhai, Xiuzhi Zhou, Hongyan Wang, Hailong Shang, Shenghong Ju, Guohua Fan, Wu Cai","doi":"10.1097/RCT.0000000000001780","DOIUrl":"https://doi.org/10.1097/RCT.0000000000001780","url":null,"abstract":"<p><strong>Aim: </strong>To investigate the predictive value of combining qualitative and quantitative parameters from dual-layer spectral detector CT (DLCT) in identifying intracranial hemorrhage (ICH) after mechanical thrombectomy (MT) in patients with acute ischemic stroke and large vessel occlusion (AIS-LVO).</p><p><strong>Materials and methods: </strong>This retrospective study consecutively enrolled 120 patients with AIS-LVO who underwent MT, followed by DLCT performed 3 hours postprocedure. After applying the inclusion and exclusion criteria, 30 patients were included in the final analysis. Two radiologists independently assessed the presence of high-density areas (HDA) on noncontrast DLCT images. Qualitative imaging signs and quantitative parameters were subsequently obtained through observation and measurement of HDAs. Follow-up CT examinations conducted during hospitalization were reviewed for ICH development. The sensitivity and specificity of the DLCT parameters for early ICH diagnosis were calculated, and the diagnostic accuracy was evaluated using receiver operating characteristic (ROC) curve analysis.</p><p><strong>Results: </strong>Fifty-five HDAs were detected on DLCT images from 30 patients. Follow-up noncontrast CT confirmed the development of ICH in 19/55 (34.5%) HDAs. Univariate analysis revealed significant differences in the mass effect, low-density edema zone, the median maximum CT value, the median cross-sectional area, the median maximum iodine concentration, the median relative iodine concentration, and the median Z-effective value between the ICH and non-ICH groups were significantly different (P < 0.05). Multivariate logistic regression identified low-density edema zone and the relative iodine concentration as independent predictors, which were incorporated into a combined diagnostic model. ROC analysis revealed an area under the curve (AUC) of 0.901 (95% CI: 0.807-0.994) for ICH prediction, with a sensitivity of 89.5% and specificity of 80.6%.</p><p><strong>Conclusions: </strong>The combination of qualitative and quantitative DLCT parameters demonstrated excellent predictive performance for identifying ICH after MT in patients with AIS-LVO.</p>","PeriodicalId":15402,"journal":{"name":"Journal of Computer Assisted Tomography","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2025-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144496810","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Pilot Study to Assess Pancreatic Adenocarcinoma Treatment Response With Iodine Density From Photon Counting CT.","authors":"Arthur Shou, Barun Bagga, Cristina Hajdu, Bari Dane","doi":"10.1097/RCT.0000000000001771","DOIUrl":"https://doi.org/10.1097/RCT.0000000000001771","url":null,"abstract":"<p><strong>Objective: </strong>To assess photon counting CT iodine density as a marker of histopathologic treatment response after neoadjuvant chemotherapy in patients with pancreatic ductal adenocarcinoma.</p><p><strong>Materials and methods: </strong>A retrospective PACS search identified 21 pancreatic ductal adenocarcinoma patients [14 men; mean (SD) age: 64 (10) y] who underwent neoadjuvant chemotherapy and pancreatic photon counting CT 2 months before resection from April 11, 2022 to February 2, 2024. The histopathologic treatment response grade was the reference standard. Freehand regions-of-interest measurements were drawn independently by 2 radiologists as large as possible within the mass on pancreatic parenchymal phase images. Attenuation, iodine density, and iodine density normalized to the aorta were recorded. Mann-Whitney U test was used to compare attenuation, iodine density, and normalized iodine density for responders (pathologic grade 1, 2) versus nonresponders (grade 3). Receiver operating characteristic curves were created, and optimal thresholds were determined with Youden's index. A P<0.05 indicated statistical significance.</p><p><strong>Results: </strong>Thirteen of 21 (61.9%) patients showed pathologic treatment response. Iodine density for nonresponders and responders was mean (SD) 0.47 (0.23) mg/mL and 1.20 (0.75) mg/mL, respectively (P=0.005). Normalized iodine density for nonresponders and responders was 7.6 (5.5)% and 22.5 (16.0)%, (P=0.006). Attenuation for nonresponders and responders was 56.5 (10.9) HU and 70.6 (17.7) HU, (P=0.04). Upon receiver operating characteristic analysis, an iodine density threshold of 0.65 mg/mL had 77% sensitivity and 88% specificity (AUC=0.86), and a normalized iodine density threshold of 10.1% had 77% sensitivity and 88% specificity (AUC=0.86) for treatment response. A 61.8 HU threshold had 77% sensitivity and 75% specificity (AUC=0.78).</p><p><strong>Conclusions: </strong>Elevated iodine density correlates with pancreatic ductal adenocarcinoma histopathologic treatment response with high specificity. Photon counting CT iodine density may be used as a marker of histopathologic treatment response.</p>","PeriodicalId":15402,"journal":{"name":"Journal of Computer Assisted Tomography","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2025-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144496809","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Quantifying the Performance of Enhanced Radiation Output, Dual-Source CT Relative to Traditional CT in Patients With Severe Obesity.","authors":"Matthew Allan Thomas, Megan C Jacobsen, Corey T Jensen, Nicolaus A Wagner-Bartak, Moiz Ahmad, Rick R Layman","doi":"10.1097/RCT.0000000000001775","DOIUrl":"https://doi.org/10.1097/RCT.0000000000001775","url":null,"abstract":"<p><strong>Objective: </strong>In CT imaging of severely obese patients, demanding clinical tasks like liver imaging may be constrained by scanner radiation output limits. This may impose an unavoidable increase in image noise and loss of image quality. In such patients, scan parameters may be restricted, leading to excessive x-ray tube heating and increased scan times that degrade exam and image consistency relative to other patients. In this study, the performance of dual-source (DS) CT with enhanced radiation output capacity was quantified relative to conventional single-source (SS) CT. The focus was on abdominopelvic imaging in severely obese patients (BMI >45 kg/m2).</p><p><strong>Methods: </strong>Abdominopelvic portal venous phase CT exams performed using DSCT were compared with exams using SSCT. General usage characteristics of the DSCT protocol were analyzed for >3000 exams over a 42-month period. More specifically, a total of 95 matched SS and DS scan pairs for the same patients were assessed in detail. The tube voltage, reconstruction method, and scanner platform were consistent in matched SS and DS scans, and changes in patient weight, diameter, and water equivalent diameter were <5%. Image global noise (GN), radiation dose (CTDIvol), and key scan parameters were compared between matched SS and DS exams.</p><p><strong>Results: </strong>The median (IQR) patient BMI was 48.4 kg/m2 (45.9-52.1 kg/m2). In the matched scan pairs, SS scans had a median (IQR) CTDIvol of 36.5 mGy (35.2-42.9 mGy) and median (IQR) GN of 14.1 HU (12.6-15.9 HU). DS scans had a significantly increased median (IQR) CTDIvol of 62.5 mGy (55.8-69.8 mGy) and reduced median (IQR) GN of 11.4 HU (10.6-12.4 HU; both P<0.001). Relative to SSCT, the DSCT protocol also enabled faster scan times at equal CTDIvol, lower tube current per x-ray tube, and improved GN consistency throughout axial slices.</p><p><strong>Conclusion: </strong>It is feasible to utilize a DSCT protocol to significantly increase radiation output, bringing image noise characteristics in line with the general patient population in abdominopelvic imaging of severely obese patients. The DSCT protocol offers a more straightforward option to attain consistency in a group of patients where achieving diagnostic CT quality has proved challenging.</p>","PeriodicalId":15402,"journal":{"name":"Journal of Computer Assisted Tomography","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2025-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144496813","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fixed Versus Tailored Scan Delay for Pancreatic Phase Acquisition: Comparison of Scan Timing Adequacy.","authors":"Yoshifumi Noda, Yukiko Takai, Masashi Asano, Nobuyuki Kawai, Tetsuro Kaga, Akio Ito, Toshiharu Miyoshi, Fuminori Hyodo, Hiroki Kato, Masayuki Matsuo","doi":"10.1097/RCT.0000000000001774","DOIUrl":"https://doi.org/10.1097/RCT.0000000000001774","url":null,"abstract":"<p><strong>Purpose: </strong>To compare the scan timing adequacy for the pancreatic phase between fixed and tailored scan delay in the pancreatic protocol CT with a bolus-tracking technique.</p><p><strong>Materials and methods: </strong>This retrospective study included patients who underwent pancreatic protocol CT using a fixed scan delay of 20 s from January 2020 to November 2022 (conventional group) and those using a tailored scan delay from January 2023 to July 2024 (tailored group). Tailored scan delay was identified to be the same as the time from contrast injection to reaching to trigger threshold of 100 HU (TimeTRIG). The scan delay ratio (SDR) was calculated by dividing the scan delay by TimeTRIG. Two radiologists assessed the scan timing adequacy for the pancreatic phase and classified it into 3 categories: early, appropriate, and late. The SDR and scan timing adequacy were compared between the conventional and tailored groups.</p><p><strong>Results: </strong>This study involved 128 patients (75 men; median age, 71 y), including 63 and 65 in the conventional and tailored groups, respectively. The median SDR was significantly different between the two groups (1.2 and 1.0 in the conventional and tailored groups; P<0.001). The proportion of appropriate scan timing for the pancreatic phase was higher in the tailored group (55/65; 84%) than in the conventional group (47/63; 75%); however, no statistical significance was observed (P = 0.36).</p><p><strong>Conclusions: </strong>The tailored scan delay tended to provide a higher rate of appropriate scan timing for the pancreatic phase compared with the conventional protocol using a fixed scan delay of 20 s.</p>","PeriodicalId":15402,"journal":{"name":"Journal of Computer Assisted Tomography","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2025-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144248082","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Predictive Value of Multiparameter Characteristics of Coronary Computed Tomography Angiography for Coronary Stent Implantation.","authors":"Xiaodie Xu, Ying Wang, Tiantian Yang, Zengkun Wang, Chu Chu, Linbing Sun, Zekai Zhao, Ting Li, Hairong Yu, Ximing Wang, Peiji Song","doi":"10.1097/RCT.0000000000001770","DOIUrl":"https://doi.org/10.1097/RCT.0000000000001770","url":null,"abstract":"<p><strong>Objective: </strong>This study aims to evaluate the predictive value of multiparameter characteristics of coronary computed tomography angiography (CCTA) plaque and the ratio of coronary artery volume to myocardial mass (V/M) in guiding percutaneous coronary stent implantation (PCI) in patients diagnosed with unstable angina.</p><p><strong>Methods: </strong>Patients who underwent CCTA and coronary angiography (CAG) within 2 months were retrospectively analyzed. According to CAG results, patients were divided into a medical therapy group (n=41) and a PCI revascularization group (n=37). The plaque characteristics and V/M were quantitatively evaluated. The parameters included minimum lumen area at stenosis (MLA), maximum area stenosis (MAS), maximum diameter stenosis (MDS), total plaque burden (TPB), plaque length, plaque volume, and each component volume within the plaque. Fractional flow reserve (FFR) and pericoronary fat attenuation index (FAI) were calculated based on CCTA. Artificial intelligence software was employed to compare the differences in each parameter between the 2 groups at both the vessel and plaque levels.</p><p><strong>Results: </strong>The PCI group had higher MAS, MDS, TPB, FAI, noncalcified plaque volume and lipid plaque volume, and significantly lower V/M, MLA, and CT-derived fractional flow reserve (FFRCT). V/M, TPB, MLA, FFRCT, and FAI are important influencing factors of PCI. The combined model of MLA, FFRCT, and FAI had the largest area under the ROC curve (AUC=0.920), and had the best performance in predicting PCI.</p><p><strong>Conclusions: </strong>The integration of AI-derived multiparameter features from one-stop CCTA significantly enhances the accuracy of predicting PCI in angina pectoris patients, evaluating at the plaque, vessel, and patient levels.</p>","PeriodicalId":15402,"journal":{"name":"Journal of Computer Assisted Tomography","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2025-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144248083","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical and Magnetic Resonance Imaging Findings for Differentiating Nodular Fasciitis and Myxofibrosarcoma: Correlation With \"Fascial Tail\" Sign.","authors":"Young Jin Choi, In Sook Lee, You Seon Song, Jeong Il Kim, Kyung Un Choi, Jaehyuck Yi","doi":"10.1097/RCT.0000000000001757","DOIUrl":"https://doi.org/10.1097/RCT.0000000000001757","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to determine the characteristic clinical and magnetic resonance imaging (MRI) findings that can distinguish nodular fasciitis (NF) from myxofibrosarcoma (MFS) because they are sometimes difficult to differentiate due to the overlapping imaging findings, such as the \"fascial tail\" sign.</p><p><strong>Methods: </strong>Thirty patients with NF and 44 with MFS were included in this study. The following MRI features were evaluated: mass size, anatomical and compartmental location, presence and type of pseudo-capsule, degree of heterogeneity, presence, and length of the \"fascial tail\" sign, and presence of peritumoral edema. Using diffusion-weighted images (DWI), we determined the presence of diffusion restriction and measured the apparent diffusion coefficient (ADC) values. On dynamic contrast-enhanced (DCE) images, we obtained the values of Ktrans, Kep, Ve, iAUC, and time-concentration curves using Tissue 4D.</p><p><strong>Results: </strong>The patients with NF were significantly younger than those with MFS. The average sizes of MFS and NF were 6.27±3.74 and 3.03±1.81 cm, respectively. Linear logistic regression analysis revealed that age, recurrence, \"fascial tail\" length, peritumoral edema, enhancement heterogeneity, and Ve differed significantly between the NF and MFS groups. The length of \"fascial tail,\" contrast heterogeneity, and compartmental location were statistically significant factors influencing the recurrence.</p><p><strong>Conclusions: </strong>Older age (above 46 y), larger tumor size (>4 cm), peritumoral edema, enhancement heterogeneity, and longer \"fascial tail\" (>25 mm) are more frequently associated with MFS, while the functional MR imaging findings, except the Ve value (>0.417), showed no significant differences.</p>","PeriodicalId":15402,"journal":{"name":"Journal of Computer Assisted Tomography","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2025-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144248081","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Quantitative Evaluation of Acute Pancreatitis Based on Dual-Energy Computed Tomography.","authors":"Yuting Lu, Linxia Wu, Xiaofei Yue, Tao Peng, Ming Yang, Jinhuang Chen, Ping Han","doi":"10.1097/RCT.0000000000001768","DOIUrl":"https://doi.org/10.1097/RCT.0000000000001768","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the value of dual-energy computed tomography (DECT) parameters for the quantitative diagnosis of acute pancreatitis (AP) and classification of its severity.</p><p><strong>Methods: </strong>Patients with AP underwent a plain CT scan and three contrast-enhanced DECT scans. We analyzed the group differences in iodine concentration (IC) and slope of the spectral Hounsfield unit curve (λHU) of the 3-phase enhanced scans (arterial, venous, and delayed phases).</p><p><strong>Results: </strong>The study included 60 AP patients (38 males and 22 females; mean age: 47.43±13.47 y). On the basis of the CT severity index (CTSI), the patients were divided into 2 groups: group A (mild AP, n=26) and group B (moderate/severe AP, n=34). IC and λHU in the arterial and venous phases were all significantly higher in group A than in group B (P<0.001) and could effectively differentiate the 2 groups. The areas under the curve were 0.753 (95% CI: 0.624-0.855), 0.799 (95% CI: 0.676-0.892), 0.774 (95% CI: 0.647-0.872), and 0.842 (95% CI: 0.724-0.923) for IC at arterial and venous phases and λHU at arterial and venous phases, respectively. These parameters decreased with the increase of CTSI, showing significant negative correlations, with r were -0.512 (95% CI: -0.678 to -0.297), -0.492 (95% CI: -0.663 to -0.272), -0.552 (95% CI: -0.707 to -0.346), -0.569 (95% CI: -0.719 to -0.368) for IC at arterial and venous phases and λHU at arterial and venous phases, respectively (P<0.001).</p><p><strong>Conclusions: </strong>DECT imaging can quantitatively analyze AP, and the IC and λHU can be used to distinguish mild and severe cases, adding functional information to the CT morphology to determine the severity and prognosis of the disease.</p>","PeriodicalId":15402,"journal":{"name":"Journal of Computer Assisted Tomography","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2025-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144150481","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Quantitative Volumetric Analysis of the Patent Foramen Ovale Tunnel in Coronary Computed Tomography Angiography: Clinical Implications and Diagnostic Significance.","authors":"Leyla Mirzayeva, Nezih Yayli, Sümeyye Nur Budak, Murat Uçar, Hüseyin Koray Kiliç, Gonca Erbaş","doi":"10.1097/RCT.0000000000001766","DOIUrl":"https://doi.org/10.1097/RCT.0000000000001766","url":null,"abstract":"<p><strong>Objectives: </strong>(a) To investigate the relationship between tunnel volume (TV) and morphologic parameters of interatrial septum (IAS) in cases with type 3 and type 4 IAS; (b) To investigate the relationship between TV of the IAS and ischemic gliotic foci in brain MRI.</p><p><strong>Materials and methods: </strong>We retrospectively reviewed the images of 301 cases who underwent CCTA in our center between 2020 and 2022. TV, tunnel length (TL), opening diameter of the right (ODRAE) and left atrium entrance (ODLAE), interatrial groove (IAG) diameter, and free flap length (FFL) were measured. The presence, number, and distribution of ischemic gliotic foci were examined in patients who had undergone brain MRI in the last 5 years before the CCTA. Pearson χ2, the Fisher Exact, Mann-Whitney U, linear regression analysis, Kruskal-Wallis test, and the Spearman correlation tests were used for statistical analysis of the data.</p><p><strong>Results: </strong>A shorter FFL was related to the higher IAS type and increased likelihood of jet flow (P=0.013). The correlation between wide IAG diameter and FFL was statistically significant (P=0.003, r=0.22). The correlation between TV and ODRAE and ODLAE was also statistically significant (P<0.001, r=0.364, P<0.001, r=0.332, respectively). In type 3 and type 4 IAS, TV was associated with an increased number of ischemic gliotic foci (P=0.008) and bilateral distribution (P=0.006) on brain MRI.</p><p><strong>Conclusion: </strong>Measurement of TL, ODRAE, ODLAE, and tunnel diameter in symptomatic cases with type 3 and type 4 IAS is crucial in determining the appropriate treatment approach. By adding the TV to the defined parameters, we thought that this innovation would contribute to invasive and noninvasive treatment management.</p>","PeriodicalId":15402,"journal":{"name":"Journal of Computer Assisted Tomography","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2025-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144003768","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}