Journal of Computer Assisted Tomography最新文献

{"title":"The Utility of Cardiac Computed Tomographic Angiography in Differentiating Between Papillary Fibroelastoma, Infective Endocarditis, and Degeneration of the Aortic Valve.","authors":"Wen-Chi Hsu, Aws Kamona, Dilek Oncel, Elliot K Fishman, Cheng Ting Lin","doi":"10.1097/RCT.0000000000001696","DOIUrl":"10.1097/RCT.0000000000001696","url":null,"abstract":"<p><strong>Purpose: </strong>Cardiac computed tomography angiography (CCTA) has significantly advanced the visualization of cardiac structures, particularly valves. We assessed the diagnostic performance of CCTA in diagnosing the most common disorders affecting the aortic valves requiring surgery-papillary fibroelastoma, infective endocarditis, and degeneration.</p><p><strong>Methods: </strong>This retrospective study included patients who underwent aortic valve resection between 2016 and 2023 and had a preceding CCTA. Pathologic diagnoses were categorized into the following 3 groups: papillary fibroelastoma, infective endocarditis, and degeneration. Each case was independently evaluated by 3 cardiac-trained radiologists.</p><p><strong>Results: </strong>The study group consisted of 50 patients with aortic valvular disorder-14 papillary fibroelastoma, 13 endocarditis, and 23 degeneration. Diagnostic accuracy varied from 70% to 74% among the 3 readers, with a pooled accuracy of 71% and consensus accuracy of 76%. Most errors involved small (≤7 mm) papillary fibroelastomas. Both papillary fibroelastomas and endocarditis-related vegetations typically presented with nodules on CT; however, nodule stalks were only observed with papillary fibroelastomas. Echocardiography aided in distinguishing between the disorders by detecting leaflet perforation and aortic regurgitation in cases of infective endocarditis.</p><p><strong>Conclusions: </strong>This study evaluated cardiac CTA for noninvasive characterization of aortic valvular disorders prior to resection. Reader accuracy ranged from 70% to 74%, improving to 76% with consensus interpretations. Small papillary fibroelastomas (≤7 mm) and overlapping imaging features, such as nodular lesions and leaflet thickening, were diagnostic challenges. Greater awareness of these CT characteristics is essential for accurate diagnosis and clinical management.</p>","PeriodicalId":15402,"journal":{"name":"Journal of Computer Assisted Tomography","volume":"49 3","pages":"417-421"},"PeriodicalIF":1.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144002631","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pseudocavity on Thin-slice CT Can Be a Suggestion of Bronchiolar Adenoma: A Preliminary Study on 80 Cases With Bronchiolar Adenoma of the Lung.","authors":"Fei Li, Yanli He, Hengli Yang, Xiaoyan Qu, Yanyan Li, Danting Shang, Gangfeng Li","doi":"10.1097/RCT.0000000000001761","DOIUrl":"https://doi.org/10.1097/RCT.0000000000001761","url":null,"abstract":"<p><strong>Objectives: </strong>At present, the study of bronchiolar adenoma (BA) mainly focuses on its pathologic characteristics, but there is limited understanding of its clinical manifestations and imaging signs. This article aims to summarize the clinical manifestations and imaging features of 80 cases of BA, with the goal of achieving a comprehensive and systematic understanding of BA.</p><p><strong>Materials and methods: </strong>We retrospectively analyzed 80 patients with BA confirmed by surgical pathology in our hospital. All subjects underwent thin-slice CT examination. The basic information, tumor history, clinical manifestations, and CT imaging features of the lesions were collected. The subjects' age, maximum diameter of BA, and shortest distance from the pleura were analyzed by t-test or 1-way ANOVA, while other clinical and radiologic characteristics were compared for differences among different BA types by the χ2 test or Fisher exact probability method.</p><p><strong>Results: </strong>The majority of the 80 patients were female, with an average age of 59.08±10.16 years. The majority of them do not manifest any clinical symptoms. All lesions are located in the subpleural area, including 63 cases in the lower lobe of the lungs. The average size of the tumors was 10.31±5.01 mm. The majority of the lesions exhibited irregular morphology (53 cases, 66.25%) and predominantly comprised solid nodules (46 cases, 57.50%). There were statistically significant differences in lesion morphology, boundary, and pseudocavity among pure ground-glass nodular BA, mixed ground-glass nodular BA, and solid density nodular BA. Compared with pure ground-glass density BA (1 case, 1.25%) and mixed ground-glass density BA (7 cases, 8.75%), the boundary of solid nodules BA (42 cases, 52.50%) was significantly clearer (P<0.001). The presence of pseudocavity was found to be significantly higher in individuals with solid nodules compared with those with pure ground-glass nodules (P<0.0167). Compared with BA without pseudocavity, BA with pseudocavity exhibited a clearer lung interface (P<0.001), more abnormal vessel signs (P=0.007), and a higher incidence of malignant preoperative diagnosis (P=0.020).</p><p><strong>Conclusions: </strong>BA mostly occurs in middle-aged and elderly women without any clinical symptoms. The imaging manifestations of BA are diverse, mainly presenting as irregular solid nodules. The interface between the tumor and lung is clear, and pseudocavity formation is common. In addition, BA with pseudocavity often exhibits abnormal vascular signs, which can lead to misdiagnosis as malignancy before surgery.</p>","PeriodicalId":15402,"journal":{"name":"Journal of Computer Assisted Tomography","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2025-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144003766","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Imaging Features and Reliability of Percutaneous Biopsy of Metanephric Adenoma of the Kidney.","authors":"Ghada Issa, Jessie L Chai, Sharath Bhagavatula, Raquel O Alencar","doi":"10.1097/RCT.0000000000001753","DOIUrl":"https://doi.org/10.1097/RCT.0000000000001753","url":null,"abstract":"<p><strong>Purpose: </strong>To describe imaging features of metanephric adenomas, assess the reliability of a diagnosis with image-guided percutaneous renal mass biopsy, and evaluate patient survival outcomes.</p><p><strong>Materials and methods: </strong>In this IRB-approved, HIPAA-compliant retrospective study, our institution's radiology report database was searched for the term \"metanephric adenoma\" from 2010 to 2020. Patient information, imaging mass characteristics, and percutaneous biopsy technique and complications were recorded. Analyses of per-tumor growth rate, per-procedure diagnostic rates, and per-patient disease-specific and metastasis-free survival were evaluated.</p><p><strong>Results: </strong>The database search yielded 8 tumors (mean diameter 2.0 cm, range 1.0 to 3.1 cm) in 8 patients (median age 60.5 y, range 40 to 66 y; 6 women) who underwent percutaneous biopsies and had imaging available for review. All tumors (8/8) were solitary, well-defined, and hypoenhancing on post-contrast images. For those with available MR, 100% (5/5) demonstrated restricted diffusion. On unenhanced CT, 62.5% (5/8) were hyperdense. The mean tumor growth rate was 0.7 mm/y (range: -0.1 to 3 mm/y) with a median imaging follow-up of 83.4 months (range: 1.6 to 198.0 mo). Specific diagnosis of metanephric adenoma on the first percutaneous biopsy was found in 75% (6/8) of patients; with repeat biopsy in 2 patients confirming metanephric adenoma. Per-patient survival outcome after a median clinical follow-up of 151.8 months (range: 1.6 to 250.6 mo) showed 100% disease-specific and metastasis-free survival.</p><p><strong>Conclusions: </strong>Metanephric adenomas are usually solitary, well-defined, and hypoenhancing masses on imaging, hyperattenuating compared with the renal parenchyma on noncontrast CT, and with restricted diffusion on MR. Image-guided percutaneous biopsy results of this tumor are reliable and safe.</p>","PeriodicalId":15402,"journal":{"name":"Journal of Computer Assisted Tomography","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2025-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143993118","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Early Experience With Postmortem CT Imaging.","authors":"Kalpana Kanal, David Zamora, Richard Harruff, Jeffrey Robinson, William Shuman, Dushyant Sahani, J Matthew Lacy, Nicole Yarid, Jonathan Medverd","doi":"10.1097/RCT.0000000000001732","DOIUrl":"https://doi.org/10.1097/RCT.0000000000001732","url":null,"abstract":"<p><strong>Objective: </strong>Postmortem computed tomography (PMCT) is a procedure fairly unfamiliar to many US radiologists. We embarked on a collaboration between the department of radiology and the medical examiner's office (MEO) with the purpose of introducing PMCT into the autopsy workflow and the goal of assisting forensic pathologist decision-making regarding the need for autopsy in determining cause of death.</p><p><strong>Methods: </strong>Establishing this service involved coordination, education, and extensive planning involving numerous professionals volunteering their time and effort. For the last 2 years, PMCT has been performed on cases requested by the MEO. Two emergency radiologists issued double-read reports detailing the PMCT findings, and the MEO completed a report detailing the PM examination process, which always included an external examination and often included an autopsy. Shared documentation summarized decedent and case information (eg, medical history), radiology primary findings and impressions, and the pathology report findings (including autopsy conclusions, when performed).</p><p><strong>Results: </strong>As of July 2024, 116 PMCT examinations have been performed, of which 64 (55.2%) underwent formal autopsy, 2 (1.7%) received limited autopsy, and 50 (43.1%) had no subsequent autopsy performed. MEO conducted external exam only when PMCT findings were conclusive for the cause of the death, demonstrating that CT had a role in supplanting the need for an autopsy. Indications for PMCT included Rule out trauma, assess extent of trauma, and family/religious objection. The manner of death for these cases was classified as accident, homicide, natural, suicide, traffic related, or undetermined.</p><p><strong>Conclusions: </strong>PMCT can be a valuable service to decedent families as well as to forensic pathologists who often operate in a limited resource environment. We anticipate that PMCT will become a standard discipline in forensic analysis. This service can often reduce the need for traditional autopsy and provides the potential to honor cultural sentiments and religious needs surrounding traditional autopsy. Establishing such a service requires the co-operation of many stakeholders, sometimes across institutional boundaries. PMCT broadens the experience of the radiologist and provides the potential for collaborative research and educational opportunities between radiology and the MEO. Lessons learned from this study may be useful for other jurisdictions implementing PMCT.</p>","PeriodicalId":15402,"journal":{"name":"Journal of Computer Assisted Tomography","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2025-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144026674","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Beyond Human Limits: The Promise and Pitfalls of Large Language Models in Radiology Research.","authors":"Chloe Reyes, Evie Nguyen, Lauren F Alexander, Rajesh Bhayana, Zoe Deahl, Ashish Khandelwal, Connor Mayes, Maria Zulfiqar, Nelly Tan","doi":"10.1097/RCT.0000000000001709","DOIUrl":"https://doi.org/10.1097/RCT.0000000000001709","url":null,"abstract":"<p><p>This review examines the applications and challenges of large language models (LLMs), like OpenAI's ChatGPT, in radiology research. ChatGPT can assist radiology researchers in generating new ideas, finding and summarizing research papers, designing studies, analyzing data, and facilitating manuscript writing. LLMs are powerful tools with numerous applications in radiology research. However, users should be mindful of potential pitfalls, such as producing incorrect or biased outputs and inconsistent responses, along with ethical and privacy concerns. We discuss approaches to optimize models and address these issues, including prompting techniques like chain-of-thought prompting, retrieval-augmented generation, and fine-tuning. For researchers, prompt engineering can be particularly effective. This review seeks to demonstrate how researchers can utilize ChatGPT for radiology research while offering strategies to mitigate associated risks. We aim to help researchers harness these potent tools to safely boost their productivity.</p>","PeriodicalId":15402,"journal":{"name":"Journal of Computer Assisted Tomography","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2025-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143968765","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pilot Study Examining the Use of DCE MRI With Pharmacokinetic Analysis to Evaluate Hypoxia in Prostate Cancer.","authors":"Eduardo Miguel Febronio, André de Freitas Secaf, Fernando Chahud, Jorge Elias, Rodolfo B Reis, Valdair F Muglia","doi":"10.1097/RCT.0000000000001707","DOIUrl":"https://doi.org/10.1097/RCT.0000000000001707","url":null,"abstract":"<p><strong>Purpose: </strong>This study aimed to investigate the association between tumor hypoxia, assessed through anti-HIF (hypoxia-inducible factor) staining, and aggressiveness in prostate cancer using a pharmacokinetic model, particularly those derived from the Tofts model, in predicting tumor aggressiveness.</p><p><strong>Material and methods: </strong>From January 2019 to April 2021, we conducted a retrospective search of patients with confirmed prostate cancer and a previous magnetic resonance imaging (MRI) examination. After exclusions, a total of 57 consecutive patients were enrolled. Patient data, including demographic, laboratory, and pathologic variables, were collected. MRI acquisition followed PI-RADS guidelines, encompassing T2-weighted, diffusion-weighted imaging, and dynamic contrast-enhanced imaging. An experienced abdominal radiologist conducted both morphologic and quantitative MRI analyses, evaluating parameters such as lesion size, apparent diffusion coefficient values, and the Tofts pharmacokinetics (TF) model. The histopathologic analysis included the International Society of Uropathology (ISUP) score and hypoxia marker immunohistochemistry.</p><p><strong>Results: </strong>There were no significant demographic and imaging differences between hypoxic and nonhypoxic tumors, except for elevated prostate-specific antigen levels in the latter and decreased normalized apparent diffusion coefficient in the former. Morphologic assessments revealed larger lesions in the hypoxia group. While Ktrans showed a positive association with hypoxia, it did not independently predict high-risk lesions.</p><p><strong>Conclusions: </strong>Our results suggest that pharmacokinetic analysis by the Tofts model was associated with tumors with hypoxia. However, this parameter was not an independent predictor of more aggressive tumors. Further studies, with a larger number of patients, multi-institutional and prospective, are needed to verify this possible association.</p>","PeriodicalId":15402,"journal":{"name":"Journal of Computer Assisted Tomography","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2025-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143995910","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Radiomics Analysis of Apparent Diffusion Coefficient Maps of Parotid Gland to Diagnose Morphologically Normal Sjogren Syndrome.","authors":"Chen Chu, Jie Meng, Huayong Zhang, Qianqian Feng, Shengnan Zhao, Weibo Chen, Jian He, Zhengyang Zhou","doi":"10.1097/RCT.0000000000001754","DOIUrl":"https://doi.org/10.1097/RCT.0000000000001754","url":null,"abstract":"<p><strong>Objective: </strong>This study investigated novel radiomic features derived from apparent diffusion coefficient (ADC) maps for diagnosing Sjögren syndrome (SS) in patients without visible magnetic resonance morphologic changes.</p><p><strong>Materials and methods: </strong>This study prospectively analyzed 119 consecutive patients with SS and 95 healthy volunteers using 3.0 T magnetic resonance imaging, including diffusion-weighted imaging with b values of 0 and 1000 s/mm2. Regions of interest (ROIs) were manually delineated along the margins of the largest parotid gland slice on ADC maps, from which 838 quantitative features were automatically extracted. Based on the intraclass correlation coefficient and absolute correlation coefficient, 45 radiomic parameters were selected for analysis. The differentiation between patients with SS and healthy controls was evaluated using univariate analysis and receiver operating characteristic analysis. Multiple radiomic features were integrated using binary logistic regression analysis. Through machine learning algorithms, 4 predictive models were developed, and each was thoroughly evaluated for predictive performance. The Shapley Additive exPlanations (SHAP) approach was employed to elucidate the predictive factors influencing the model.</p><p><strong>Results: </strong>Twenty-two radiomic parameters demonstrated significant differences between SS and control groups. The AUCs were 0.681 ± 0.100 (0.559~0.878). The optimal diagnostic combination for SS consisted of 6 parameters: 0.975Quantile, 180dr_D(4)_Cluster Prominence, 225dr_D(7)_Entropy, 315dr_D(7)_Entropy, Compactness2, and Max3D Diameter, achieving an AUC of 0.956. The SVM, GBM, and XGBoost models were effectively distinguished SS from healthy controls. Among all the parameters, Max3DDiameter demonstrated the strongest predictive power in the model.</p><p><strong>Conclusions: </strong>Radiomic features derived from ADC maps demonstrate significant potential in facilitating the early diagnosis of SS.</p>","PeriodicalId":15402,"journal":{"name":"Journal of Computer Assisted Tomography","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2025-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144023722","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of Computed Tomography/Magnetic Resonance Imaging Characteristics of Acute Pancreatitis Between Cholecystectomy and Non-cholecystectomy Patients.","authors":"Zi Sheng Zhao, Di Tao, Jun Hui Chen, Xing Hui Li, Yi Fan Ji, Xiao Ming Zhang","doi":"10.1097/RCT.0000000000001760","DOIUrl":"https://doi.org/10.1097/RCT.0000000000001760","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to compare computed tomography (CT)/magnetic resonance imaging (MRI) characteristics of acute pancreatitis (AP) between patients with cholecystectomy and non-cholecystectomy and to validate the effect of prior cholecystectomy on the severity of subsequent pancreatitis.</p><p><strong>Methods: </strong>This retrospective study included 384 inpatients with AP at our hospital from January 1, 2020 to December 31, 2023. Based on their history of cholecystectomy, the patients were split into cholecystectomy and non-cholecystectomy groups. propensity score matching was applied, considering age and sex, in a 1:3 ratio. Demographic, clinical, laboratory, and CT/MRI parameters of each group were analyzed.</p><p><strong>Results: </strong>There were 200 (52.1%) males and 184 (47.9%) females, with a mean age of 53.55 ± 13.86 years (range: 18-98 y). Ninety-six patients were in the cholecystectomy group that had previously undergone cholecystectomy, and 288 in the non-cholecystectomy group. Creatinine and C-reactive protein levels were lower in the patients with cholecystectomy than in patients with non-cholecystectomy (P1 = 0.001, P2 = 0.049). In the prevalence of biliary pancreatitis, the cholecystectomy patients are 27.1%, whereas the non-cholecystectomy patients are 45.8% (P = 0.005). The non-cholecystectomy patients had a significantly higher mean CT/MRI severity index score (3.57 ± 1.72 points) than the cholecystectomy group (3.00 ± 1.58 points; P < 0.001). Regarding local complications, In the groups that underwent cholecystectomy and those that did not, the prevalence of acute peripancreatic fluid collection was 40.4% and 21.9%, respectively. (P < 0.001).</p><p><strong>Conclusions: </strong>AP following cholecystectomy exhibits unique imaging characteristics. Cholecystectomy reduces the severity and acute peripancreatic fluid collection rate of subsequent pancreatitis on CT/MRI.</p>","PeriodicalId":15402,"journal":{"name":"Journal of Computer Assisted Tomography","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2025-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144026944","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"CT Evaluation of Labyrinth Structures in Patients With Incomplete Partition Type II Anomaly.","authors":"Ipek Sel, Abdullah Soydan Mahmutoglu, Yesim Karagoz, Direnc Ozlem Aksoy, Ece Ates Kus","doi":"10.1097/RCT.0000000000001758","DOIUrl":"https://doi.org/10.1097/RCT.0000000000001758","url":null,"abstract":"<p><strong>Objective: </strong>Incomplete partition type II (IP-II) is one of the most common inner ear malformations that necessitates cochlear implantation. It is characterized by a cystic cochlear apex resulting from the coalescence of middle and apical turns due to modiolar hypoplasia and distal interscalar septal defect. Radiologic diagnosis of IP-II anomaly could be difficult with equivocal changes in tiny labyrinthine structures, especially with inexperienced observers. In our study, we aimed to determine pertinent quantitative radioanatomical measurements of inner ear structures (lateral interscalar notch angle, lateral interscalar notch depth, and lateral height) that may contribute to the diagnosis of IP-II anomaly using temporal bone high-resolution computed tomography (HRCT).</p><p><strong>Methods: </strong>Our study was a retrospective case-control study approved by the institutional review board. We retrospectively reviewed temporal bone HRCT examinations for the preoperative assessment of cochlear implantation of patients with sensorineural hearing loss (SNHL), using the diagnosis code of IP-II anomaly. Patients with SNHL and a radiologic diagnosis of IP-II anomaly according to the Sennaroglu classification were recruited. Thirty-four SNHL patients with IP-II anomaly (66 ears) and 24 patients without SNHL (48 ears) who underwent temporal CT imaging for inflammatory conditions or trauma not involving labyrinthine structures were included in the study. The lateral interscalar notch angle, lateral interscalar notch depth, and lateral height were independently measured by 2 observers (a senior head and neck radiologist and a novice radiologist). The parameters measured in patient and control groups were compared using the Mann-Whitney U test, and interobserver reliability was calculated.</p><p><strong>Results: </strong>Lateral interscalar notch angle and lateral height values were found to be significantly larger, while lateral interscalar notch depth value was significantly smaller in the IP-II group (P<0.05). The agreement between the observers in all measurements, evaluated separately in IP-II and control groups, was excellent (P<0.05). The cutoff values for determining the IP-II anomaly were found to be consistent between the 2 observers, with high sensitivity and specificity.</p><p><strong>Conclusions: </strong>CT measurements of inner ear structures in SNHL could help to diagnose IP-II anomalies, especially in patients with equivocal audiological and radiologic findings. This study validates CT measurements in the evaluation of IP-II anomaly conducted by histologic specimens and MRI in previous studies. Lateral cochlear measurements with an angle of >130 degrees, a depth of ≤0.35 mm, and a height of >3.15 mm could support the diagnosis of the IP-II anomaly. These measurements are also reproducible.</p>","PeriodicalId":15402,"journal":{"name":"Journal of Computer Assisted Tomography","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2025-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143968240","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Photon-counting CT for Chest Imaging-What Have We Learned So Far?","authors":"Fides R Schwartz","doi":"10.1097/RCT.0000000000001756","DOIUrl":"https://doi.org/10.1097/RCT.0000000000001756","url":null,"abstract":"<p><p>CT imaging has advanced significantly, with dual-energy CT (DECT) marking a milestone by using 2 energy spectra for enhanced tissue characterization. The latest innovation is photon-counting detectors (PCD), which offer superior spatial resolution, contrast-to-noise ratio (CNR), and potential for reduced radiation dose compared with traditional energy-integrating detectors (EID). Photon-counting CT (PCD-CT), which directly counts individual photons using semiconductors, has important implications for chest imaging, especially for complex disease processes that benefit from imaging at higher spatial resolution. PCD-CT achieves improved spatial resolution by eliminating the blurring effects associated with EID scintillators. Enhanced CNR is achieved through energy discrimination and selective use of photon energies, which also helps to minimize electronic noise. PCD-CT facilitates significant radiation dose reduction, particularly valuable for patients who receive regular follow-ups, like in lung cancer screening. In addition, PCD-CT provides spectral capabilities in every scan, unlike DECT, which requires preselecting a specific spectral scan mode. In chest imaging, PCD-CT shows promise in detecting and definitively characterizing infectious diseases, interstitial lung disease, malignancies, and vascular conditions at low radiation doses, offering higher diagnostic accuracy and patient safety. Despite these advancements, challenges remain in optimizing spectral imaging and integrating PCD-CT into routine clinical workflows, necessitating ongoing research and development.</p>","PeriodicalId":15402,"journal":{"name":"Journal of Computer Assisted Tomography","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2025-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144007376","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}