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Respiratory Patterns in Neurological Injury, Pathophysiology, Ventilation Management, and Future Innovations: A Systematic Review. 神经损伤的呼吸模式、病理生理学、通气管理和未来创新：系统回顾。
4区 化学
Journal of Carbohydrate Chemistry Pub Date : 2023-10-01 Epub Date: 2022-09-28 DOI: 10.14218/erhm.2022.00081
Matthew Goldman, Brandon Lucke-Wold, Jason Katz, Bavly Dawoud, Abeer Dagra
{"title":"Respiratory Patterns in Neurological Injury, Pathophysiology, Ventilation Management, and Future Innovations: A Systematic Review.","authors":"Matthew Goldman, Brandon Lucke-Wold, Jason Katz, Bavly Dawoud, Abeer Dagra","doi":"10.14218/erhm.2022.00081","DOIUrl":"10.14218/erhm.2022.00081","url":null,"abstract":"<p><p>Traumatic brain injuries (TBI), ischemic stroke, hemorrhagic stroke, brain tumors, and seizures have diverse and sometimes overlapping associated breathing patterns. Homeostatic mechanisms for respiratory control are intertwined with complex neurocircuitry, both centrally and peripherally. This paper summarizes the neurorespiratory control and pathophysiology of its disruption. It also reviews the clinical presentation, ventilatory management, and emerging therapeutics. This review additionally serves to update all recent preclinical and clinical research regarding the spectrum of respiratory dysfunction. Having a solid pathophysiological foundation of disruptive mechanisms would permit further therapeutic development. This novel review bridges experimental/physiological data with bedside management, thus allowing neurosurgeons and intensivists alike to rapidly diagnose and treat respiratory sequelae of acute brain injury.</p>","PeriodicalId":15311,"journal":{"name":"Journal of Carbohydrate Chemistry","volume":"20 1","pages":"338-349"},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83026169","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Bacterial cellulose-based hydrogels carrying Lewis X trisaccharides as a system for monitoring carbohydrate–carbohydrate interactions with the naked eye 细菌纤维素基水凝胶携带Lewis X三糖，作为肉眼监测碳水化合物-碳水化合物相互作用的系统
IF 1 4区 化学
Journal of Carbohydrate Chemistry Pub Date : 2023-08-06 DOI: 10.1080/07328303.2023.2242927
Jiayu Dong, Katsunari Hiroki, M. Tobito, Keisuke Yoshida, Ai Tanabe, T. Shindo, Megu Gunji, Qintong Li, Teruaki Hasegawa
{"title":"Bacterial cellulose-based hydrogels carrying Lewis X trisaccharides as a system for monitoring carbohydrate–carbohydrate interactions with the naked eye","authors":"Jiayu Dong, Katsunari Hiroki, M. Tobito, Keisuke Yoshida, Ai Tanabe, T. Shindo, Megu Gunji, Qintong Li, Teruaki Hasegawa","doi":"10.1080/07328303.2023.2242927","DOIUrl":"https://doi.org/10.1080/07328303.2023.2242927","url":null,"abstract":"","PeriodicalId":15311,"journal":{"name":"Journal of Carbohydrate Chemistry","volume":"1 1","pages":""},"PeriodicalIF":1.0,"publicationDate":"2023-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44791093","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Two new species of the Phaoniaboleticola-group (Diptera, Muscidae, Phaoniinae) from China. 来自中国的两个 Phaoniaboleticola 群新种（双翅目，鹟科，Phaoniinae）。
IF 1.3 4区 化学
Journal of Carbohydrate Chemistry Pub Date : 2023-07-03 eCollection Date: 2023-01-01 DOI: 10.3897/zookeys.1168.97845
Zhongyan Zhou, Lianmeng Wei
{"title":"Two new species of the <i>Phaoniaboleticola</i>-group (Diptera, Muscidae, Phaoniinae) from China.","authors":"Zhongyan Zhou, Lianmeng Wei","doi":"10.3897/zookeys.1168.97845","DOIUrl":"10.3897/zookeys.1168.97845","url":null,"abstract":"<p><p>Two new species of <i>Phaonia</i> are described: <i>Phaoniaagitata</i> Zhou & Wei, <b>sp. nov.</b> and <i>Phaonianujiangensis</i> Zhou & Wei, <b>sp. nov.</b>, which were collected from Guizhou and Yunnan provinces of southwestern China and are assigned to the <i>boleticola</i>-group. A key to the species of this group is provided. The type specimens are deposited in the Wei Lianmeng Model Worker Innovation Studio, Anshun, Guizhou, China (WLMWISAGC).</p>","PeriodicalId":15311,"journal":{"name":"Journal of Carbohydrate Chemistry","volume":"12 1","pages":"219-229"},"PeriodicalIF":1.3,"publicationDate":"2023-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10848857/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81753757","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Advances in the synthesis of antiviral agents from carbohydrate-derived chiral pools 糖源性手性池合成抗病毒药物的研究进展
IF 1 4区 化学
Journal of Carbohydrate Chemistry Pub Date : 2022-01-01 DOI: 10.1080/07328303.2023.2189473
Anjali Sharma , Smritilekha Bera , Dhananjoy Mondal
{"title":"Advances in the synthesis of antiviral agents from carbohydrate-derived chiral pools","authors":"Anjali Sharma ,&nbsp;Smritilekha Bera ,&nbsp;Dhananjoy Mondal","doi":"10.1080/07328303.2023.2189473","DOIUrl":"10.1080/07328303.2023.2189473","url":null,"abstract":"<div><p>Carbohydrates are the most abundant natural products and a major component on the cell surface of living beings. They are useful building blocks of various natural products and organic synthesis due to their presence of multiple chiral centers and hydroxy groups. The recent outbreak of COVID-19 and other life-threatening viral infections necessitates the development of potent antiviral drugs. In this review, we focused on the synthesis of antiviral drugs to treat influenza, HIV, herpes, hepatitis, and other diseases, from different monosaccharides such as D-glucose, D-mannose, D-xylose, <em>N</em>-acetyl-D-glucosamine, D-gluconolactone, etc., such as anti-influenza drugs remdesivir, Tamiflu, zanamivir, and so on.</p><p><span><figure><span><img><ol><li><span>Download : <span>Download high-res image (247KB)</span></span></li><li><span>Download : <span>Download full-size image</span></span></li></ol></span></figure></span></p></div>","PeriodicalId":15311,"journal":{"name":"Journal of Carbohydrate Chemistry","volume":"41 7","pages":"Pages 424-510"},"PeriodicalIF":1.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42321811","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
New macrocycles incorporating glycolipids via copper-catalyzed triazole coupling 通过铜催化的三唑偶联结合糖脂的新大环
IF 1 4区 化学
Journal of Carbohydrate Chemistry Pub Date : 2022-01-01 DOI: 10.1080/07328303.2022.2039685
Nuha S. Kareem , Shaymaa A. Mohammed , May Jaleel Abed , Asaad H. Aneed , Hayder M. Kamal , N. Idayu Zahid , Karem J. Sabah
{"title":"New macrocycles incorporating glycolipids via copper-catalyzed triazole coupling","authors":"Nuha S. Kareem ,&nbsp;Shaymaa A. Mohammed ,&nbsp;May Jaleel Abed ,&nbsp;Asaad H. Aneed ,&nbsp;Hayder M. Kamal ,&nbsp;N. Idayu Zahid ,&nbsp;Karem J. Sabah","doi":"10.1080/07328303.2022.2039685","DOIUrl":"10.1080/07328303.2022.2039685","url":null,"abstract":"<div><p>A series of new macrocycles based on alkyl glycosides derived from D-glucose and D-galactose was synthesized. The macrocycles were easily obtained by the reaction of dialkynyl derivatives with diazides via copper-catlyzed 1,3-cycloaddition reaction. Simple protecting group strategies were applied to obtain the vicinal dihydroxy derivatives, followed by Williamson etherification with propargyl bromides to get the dialkynyl derivatives. These derivatives were subjected to 1,3-Hüisgen triazole coupling with diazides furnishing the macrocycles in good yields. The 1,3-Hüisgen reaction used to build these macrocycles was investigated thoroughly with respect to reaction time, catalysts, solvents, and temperature for optimum macrocyclisation.</p></div>","PeriodicalId":15311,"journal":{"name":"Journal of Carbohydrate Chemistry","volume":"41 1","pages":"Pages 1-17"},"PeriodicalIF":1.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44472605","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Highly stereoselective construction of 1,2-cis-D-quinovosamine glycosides for the synthesis of Pseudomonas aeruginosa O-antigen disaccharide 1,2-顺式- d -喹啉氨基糖苷的高立体选择性构建合成铜绿假单胞菌o抗原双糖
IF 1 4区 化学
Journal of Carbohydrate Chemistry Pub Date : 2022-01-01 DOI: 10.1080/07328303.2022.2055049
Hongli Hou , Guangzong Tian , Junjie Fu , Chunjun Qin , Guodong Chen , Xiaopeng Zou , Jing Hu , Jian Yin
{"title":"Highly stereoselective construction of 1,2-cis-D-quinovosamine glycosides for the synthesis of Pseudomonas aeruginosa O-antigen disaccharide","authors":"Hongli Hou ,&nbsp;Guangzong Tian ,&nbsp;Junjie Fu ,&nbsp;Chunjun Qin ,&nbsp;Guodong Chen ,&nbsp;Xiaopeng Zou ,&nbsp;Jing Hu ,&nbsp;Jian Yin","doi":"10.1080/07328303.2022.2055049","DOIUrl":"10.1080/07328303.2022.2055049","url":null,"abstract":"<div><p>The highly stereoselective synthesis of complex carbohydrates containing 1,2-<em>cis</em>-quinovosamine is an on-going challenge. Here, we report a synergistic strategy of merging reagent modulation and acyl remote participation for highly stereoselective construction of 1,2-<em>cis</em>-D-quinovosamine linkages. The strategy is applied to the preparation of natural disaccharide present on the surface of <em>Pseudomonas aeruginosa</em> bacteria. The resulting disaccharide can be covalently bound to microarray surface or carrier via the aminopentyl linker at the reducing end, allowing for exploring its antigenic and immunogenic properties.</p></div>","PeriodicalId":15311,"journal":{"name":"Journal of Carbohydrate Chemistry","volume":"41 2","pages":"Pages 155-180"},"PeriodicalIF":1.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44036718","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The structural diversity of natural glycosphingolipids (GSLs) 天然鞘糖脂的结构多样性
IF 1 4区 化学
Journal of Carbohydrate Chemistry Pub Date : 2022-01-01 DOI: 10.1080/07328303.2022.2063308
Zhongwu Guo
{"title":"The structural diversity of natural glycosphingolipids (GSLs)","authors":"Zhongwu Guo","doi":"10.1080/07328303.2022.2063308","DOIUrl":"10.1080/07328303.2022.2063308","url":null,"abstract":"<div><p>Glycosphingolipids (GSLs) are a subclass of glycolipids made of a glycan and a ceramide that, in turn, is composed of a sphingoid base moiety and a fatty acyl group. GSLs represent the vast majority of glycolipids in eukaryotes, and as an essential component of the cell membrane, they play an important role in many biological and pathological processes. Therefore, they are useful targets for the development of novel diagnostic and therapeutic methods for human diseases. Since sphingosine was first described by J. L. Thudichum in 1884, several hundred GSL species, not including their diverse lipid forms that can further amplify the number of individual GSLs by many folds, have been isolated from natural sources and structurally characterized. This review tries to provide a comprehensive survey of the major GSL species, especially those with distinct glycan structures and modification patterns, and the ceramides with unique modifications of the lipid chains, that have been discovered to date. In particular, this review is focused on GSLs from eukaryotic species. This review has listed 251 GSL glycans with different linkages, 127 glycans with unique modifications, 46 sphingoids, and 43 fatty acyl groups. It should be helpful for scientists who are interested in GSLs, from isolation and structural analyses to chemical and enzymatic syntheses, as well as their biological studies and applications.</p></div>","PeriodicalId":15311,"journal":{"name":"Journal of Carbohydrate Chemistry","volume":"41 2","pages":"Pages 63-154"},"PeriodicalIF":1.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10427639","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Design and synthesis of 4-azido-phosphatidylinositol as a potential probe for metabolic engineering of glycosylphosphatidylinositol on cells 设计与合成4-叠氮-磷脂酰肌醇作为糖基磷脂酰肌醇在细胞上代谢工程的潜在探针
IF 1 4区 化学
Journal of Carbohydrate Chemistry Pub Date : 2022-01-01 DOI: 10.1080/07328303.2022.2077358
Kendall C. Craig , Zhongwu Guo
{"title":"Design and synthesis of 4-azido-phosphatidylinositol as a potential probe for metabolic engineering of glycosylphosphatidylinositol on cells","authors":"Kendall C. Craig ,&nbsp;Zhongwu Guo","doi":"10.1080/07328303.2022.2077358","DOIUrl":"10.1080/07328303.2022.2077358","url":null,"abstract":"<div><p>A diacyl phosphatidylinositol (PI) derivative with an azide linked to its inositol C4-position was effectively synthesized in 19 steps for the longest linear sequence and in a <em>ca</em>. 1% overall yield from 1,2-distearoyl-<em>sn</em>-glycerol and D-glucose. This compound was designed as a biosynthetic precursor of glycosylphosphatidylinositol (GPI) anchors. Its azide would enable further modification to introduce other molecular tags by a biocompatible click reaction. Therefore, it can be a useful probe for metabolic engineering of cell surface GPI anchors and GPI-anchored proteins.</p><p><span><figure><span><img><ol><li><span>Download : <span>Download high-res image (26KB)</span></span></li><li><span>Download : <span>Download full-size image</span></span></li></ol></span></figure></span></p></div>","PeriodicalId":15311,"journal":{"name":"Journal of Carbohydrate Chemistry","volume":"41 4","pages":"Pages 238-248"},"PeriodicalIF":1.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10474761","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Arabinogalactan from Ixeris chinensis (Thunb.) Nakai as a stabilizer to decorate SeNPs and enhance their anti-hepatocellular carcinoma activity via the mitochondrial pathway 阿拉伯半乳聚糖(阿拉伯语:Ixeris chinensis)Nakai作为一种稳定剂，通过线粒体途径修饰SeNPs并增强其抗肝癌活性
IF 1 4区 化学
Journal of Carbohydrate Chemistry Pub Date : 2022-01-01 DOI: 10.1080/07328303.2022.2105860
Hongyan Li , Yifan Wang , Yan Chen , Shuxin Wang , Yifan Zhao , Jinyuan Sun
{"title":"Arabinogalactan from Ixeris chinensis (Thunb.) Nakai as a stabilizer to decorate SeNPs and enhance their anti-hepatocellular carcinoma activity via the mitochondrial pathway","authors":"Hongyan Li ,&nbsp;Yifan Wang ,&nbsp;Yan Chen ,&nbsp;Shuxin Wang ,&nbsp;Yifan Zhao ,&nbsp;Jinyuan Sun","doi":"10.1080/07328303.2022.2105860","DOIUrl":"10.1080/07328303.2022.2105860","url":null,"abstract":"<div><p>Arabinogalactan (ICPA) was isolated from the medicinal plant <em>Ixeris chinensis</em> (Thunb.) Nakai, and was used as the reducing agent to stabilize selenium nanoparticles (SeNPs). ICPA-decorated SeNPs (ICPA-SeNPs) were synthesized with Na<sub>2</sub>SeO<sub>3</sub> and ICPA, and their average diameter was 82.6<!--> <!-->±<!--> <!-->2.5 nm. ICPA-SeNPs had good dispersity in phosphate-buffered saline (PBS) with a hydrodynamic size of 156.2<!--> <!-->±<!--> <!-->2.8 nm. They were stable in PBS solution with a zeta potential of −24.8<!--> <!-->±<!--> <!-->0.6 mV. The anti-hepatoma activity of ICPA-SeNPs was investigated <em>in vitro</em>. ICPA-SeNPs significantly suppressed the growth of SMMC-7721 and HepG2 hepatoma cells. They entered SMMC-7721 cells via energy- and caveolae-dependent endocytosis. ICPA-SeNPs were able to increase reactive oxygen species levels, reduce mitochondrial membrane potential, and increase caspase-3 expression in SMMC-7721 cells, which led to the apoptosis of SMMC-7721 cells. They also arrested the cell cycle of SMMC-7721 cells in the S phase. These findings indicate that ICPA could enhance the stability of SeNPs and inhibit SMMC-7721 cell proliferation via the mitochondrial pathway. ICPA-SeNPs could be developed as an antitumor agent for hepatocellular carcinoma treatment.</p></div>","PeriodicalId":15311,"journal":{"name":"Journal of Carbohydrate Chemistry","volume":"41 5","pages":"Pages 329-345"},"PeriodicalIF":1.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49111345","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
An efficient method for the cleavage of tert-butyldiphenylsilyl ethers catalyzed by 1,3-dibromo-5,5-dimethylhydantoin 1,3-二溴-5,5-二甲基乙内酰脲催化叔丁基二苯基甲硅烷基醚裂解的有效方法
IF 1 4区 化学
Journal of Carbohydrate Chemistry Pub Date : 2022-01-01 DOI: 10.1080/07328303.2022.2031206
Zong Han
{"title":"An efficient method for the cleavage of tert-butyldiphenylsilyl ethers catalyzed by 1,3-dibromo-5,5-dimethylhydantoin","authors":"Zong Han","doi":"10.1080/07328303.2022.2031206","DOIUrl":"10.1080/07328303.2022.2031206","url":null,"abstract":"Abstract An efficient method for the deprotection of tert-butyldiphenylsilyl (TBDPS) ethers using 1,3-dibromo-5,5-dimethylhydantoin (DBH) as catalyst and dimethyl sulfoxide (DMSO) as solvent has been established. This method is useful for many kinds of compounds, such as carbohydrates, steroids, benzyl alcohols and primary fatty alcohols. Substrates bearing acetates, benzoates, pivaloates, mesylates, and benzyl and p-methoxybenzyl ethers are compatible. Graphical abstract","PeriodicalId":15311,"journal":{"name":"Journal of Carbohydrate Chemistry","volume":"41 1","pages":"Pages 51-62"},"PeriodicalIF":1.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41626808","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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