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2013 39th Annual Northeast Bioengineering Conference最新文献

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Multiresolution Image Analysis for Automatic Quantification of Collagen Gel Contraction 用于胶原凝胶收缩自动定量的多分辨率图像分析
2013 39th Annual Northeast Bioengineering Conference Pub Date : 2013-04-05 DOI: 10.1109/NEBEC.2013.115
Hsin-Chen Chen, Tai-Hua Yang, A. Thoreson, Chunfeng Zhao, P. Amadio, F. Su, Wenyan Jia, Yung-Nien Sun, K. An, Mingui Sun
{"title":"Multiresolution Image Analysis for Automatic Quantification of Collagen Gel Contraction","authors":"Hsin-Chen Chen, Tai-Hua Yang, A. Thoreson, Chunfeng Zhao, P. Amadio, F. Su, Wenyan Jia, Yung-Nien Sun, K. An, Mingui Sun","doi":"10.1109/NEBEC.2013.115","DOIUrl":"https://doi.org/10.1109/NEBEC.2013.115","url":null,"abstract":"Quantifying collagen gel contraction is important in tissue engineering and biological research because it provides spatial-temporal assessments of cell behaviors and tissue material properties. However, these assessments currently rely on manual processing, which is time-consuming and subjective to personal opinions. We present a multiresolution image analysis system for automatic quantification of gel contraction. This system includes a color conversion process to normalize and enhance the contrast between gel and background. Then, a deformable circular model is activated automatically to capture details of gel boundaries. These steps are coordinated by a multiresolution strategy. The target measurements are obtained after gel segmentation. Our experiments using 30 images demonstrated a high consistency between the proposed and manual segmentation methods. The system can process large-size images (4000×3000) at a rate of approximately one second per image. It thus serves as a useful tool for analyzing large biological and biomaterial imaging datasets efficiently and objectively.","PeriodicalId":153112,"journal":{"name":"2013 39th Annual Northeast Bioengineering Conference","volume":"96 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2013-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125145520","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Development of a Pressure-Sensing Handle for a Stethoscope 听诊器压力感应手柄的研制
2013 39th Annual Northeast Bioengineering Conference Pub Date : 2013-04-05 DOI: 10.1109/NEBEC.2013.82
Brittany Alphonse, A. Spiewak, Erik Walder, G. Comtois, E. Chabot, Ying Sun
{"title":"Development of a Pressure-Sensing Handle for a Stethoscope","authors":"Brittany Alphonse, A. Spiewak, Erik Walder, G. Comtois, E. Chabot, Ying Sun","doi":"10.1109/NEBEC.2013.82","DOIUrl":"https://doi.org/10.1109/NEBEC.2013.82","url":null,"abstract":"Acoustic signals recorded with a stethoscope could be significantly affected by the probe-skin interface. The goal of this study was to develop a pressure-sensing device to measure and control the applied pressure at the probe-skin interface. Since placing a pressure sensor directly at the interface would block the transfer of acoustic signals, a custom-made handle was attached to the top of the stethoscope head. A handle was made of silicone rubber with an embedded pressure sensor that measures the force transferring from the hand to the stethoscope head. A microprocessor based device was also developed to provide a numerical readout of the force. This system was successfully built, providing accurate and repeatable pressure measurements. The resulting device should be useful for standardizing the applied pressure at the probe-skin interface for acoustic measurements with a stethoscope.","PeriodicalId":153112,"journal":{"name":"2013 39th Annual Northeast Bioengineering Conference","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2013-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130445998","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Complete Analytical Model for Different Variations of FinFET 不同变化FinFET的完整解析模型
2013 39th Annual Northeast Bioengineering Conference Pub Date : 2013-04-05 DOI: 10.1109/NEBEC.2013.6
J. Mohseni, J. Meindl
{"title":"Complete Analytical Model for Different Variations of FinFET","authors":"J. Mohseni, J. Meindl","doi":"10.1109/NEBEC.2013.6","DOIUrl":"https://doi.org/10.1109/NEBEC.2013.6","url":null,"abstract":"Here we present a complete analytical model that characterizes all the variations of multi-gate MOSFETs including the Tri-gate FinFET (Figure 1), all-around gate FinFET, Trapezoidal FinFET, Double-gate MOSFET, etc. Next we present a complete comparison between ideal rectangular FinFETs and trapezoidal FinFETs. Finally, for the first time, we present the ultimate limit for scaling of rectangular and trapezoidal FinFETs.","PeriodicalId":153112,"journal":{"name":"2013 39th Annual Northeast Bioengineering Conference","volume":"66 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2013-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121474486","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
EMG-Torque Estimation at Future Times 肌电-扭矩估计在未来的时间
2013 39th Annual Northeast Bioengineering Conference Pub Date : 2013-04-05 DOI: 10.1109/NEBEC.2013.88
Kishor Koirala, Meera Dasog, Pu Liu, E. Clancy
{"title":"EMG-Torque Estimation at Future Times","authors":"Kishor Koirala, Meera Dasog, Pu Liu, E. Clancy","doi":"10.1109/NEBEC.2013.88","DOIUrl":"https://doi.org/10.1109/NEBEC.2013.88","url":null,"abstract":"This paper investigates the ability of surface electromyogram (EMG) to estimate joint torque at future times, up to 1 s. EMG was recorded from the biceps and triceps muscles of 54 subjects during constant-posture, force-varying contractions and related to the torque produced about the elbow. EMG to joint torque was predicted up to 80 ms into the future without any changes in the minimum least square error of 5.48% of maximum voluntary contraction for the best estimation model investigated: whitened, multiple-channel EMG used with a nonlinear model. Error progressively increased for prediction times above 80 ms.","PeriodicalId":153112,"journal":{"name":"2013 39th Annual Northeast Bioengineering Conference","volume":"436 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2013-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123099112","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Testing a Multi-wavelength, Multi-distance fNIR Probe as a Measure of Cerebral Oxygen Saturation for Use in a Feedback Titrated Oxygen Delivery System 测试多波长，多距离fNIR探针作为脑氧饱和度的测量，用于反馈滴定供氧系统
2013 39th Annual Northeast Bioengineering Conference Pub Date : 2013-04-05 DOI: 10.1109/NEBEC.2013.30
A. Verghese, K. Izzetoglu, Richard Hamilton, K. Barbee, B. Ben Dor, Juan Du
{"title":"Testing a Multi-wavelength, Multi-distance fNIR Probe as a Measure of Cerebral Oxygen Saturation for Use in a Feedback Titrated Oxygen Delivery System","authors":"A. Verghese, K. Izzetoglu, Richard Hamilton, K. Barbee, B. Ben Dor, Juan Du","doi":"10.1109/NEBEC.2013.30","DOIUrl":"https://doi.org/10.1109/NEBEC.2013.30","url":null,"abstract":"This project aims to demonstrate that the multi-wavelength, multi-distance fNIR probe can function as a reliable measure of cerebral oxygen saturation. The probe will then be used in a project to create a feedback titrated system of oxygen delivery. Current treatment methods for patients receiving supplemental oxygen do not respond dynamically to the patient's lifestyle, but rather give a fixed dose of oxygen. Our project proposes to develop a system that bases the amount of oxygen delivered to the patient on the oxygen saturation of his or her own blood. This should improve patient care helping to personalize oxygen therapy.","PeriodicalId":153112,"journal":{"name":"2013 39th Annual Northeast Bioengineering Conference","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2013-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115317074","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Detection of User Intent in Neurorehablitation Using a Commercial EEG Headset 使用商用脑电图耳机检测神经康复中的用户意图
2013 39th Annual Northeast Bioengineering Conference Pub Date : 2013-04-05 DOI: 10.1109/NEBEC.2013.14
Abhineet Mishra, R. Foulds
{"title":"Detection of User Intent in Neurorehablitation Using a Commercial EEG Headset","authors":"Abhineet Mishra, R. Foulds","doi":"10.1109/NEBEC.2013.14","DOIUrl":"https://doi.org/10.1109/NEBEC.2013.14","url":null,"abstract":"Neurorehabilitation has recently been augmented with the use of virtual reality and rehabilitation robotics. In each case a necessary condition for success is the linkage of user intent to the interventions. In many systems, some known volitional control must exist in order to synchronize the user intended movement with the therapeutic virtual or robotic movement. Individuals without such residual movements are unable to fully benefit from these therapies. This project demonstrates the feasibility of using a low cost, commercial EEG system with BCI2000 software [3] to access the imagined movement without the need for physical movement.","PeriodicalId":153112,"journal":{"name":"2013 39th Annual Northeast Bioengineering Conference","volume":"3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2013-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127032626","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Exploring Model Integration through Quantized Information Flow 通过量化信息流探索模型集成
2013 39th Annual Northeast Bioengineering Conference Pub Date : 2013-04-05 DOI: 10.1109/NEBEC.2013.94
Y. Derbal
{"title":"Exploring Model Integration through Quantized Information Flow","authors":"Y. Derbal","doi":"10.1109/NEBEC.2013.94","DOIUrl":"https://doi.org/10.1109/NEBEC.2013.94","url":null,"abstract":"The paper explores the integration of coarse-grained model abstractions using feedback of quantized information flow. The modeling and simulation of the lytic induction cycle of lambda phage is used as an illustrative example. The simulation results show that the model, with its modest complexity, has the capacity to internalize the relevant transcription regulatory logic and replicate the salient dynamics of the lytic induction cycle.","PeriodicalId":153112,"journal":{"name":"2013 39th Annual Northeast Bioengineering Conference","volume":"9 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2013-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123748303","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Biocompatibility of CaO-Na2O-SiO2/TiO2 Glass Ceramic Scaffolds for Orthopaedic Applications 骨科用cao - na20 - sio2 /TiO2玻璃陶瓷支架的生物相容性研究
2013 39th Annual Northeast Bioengineering Conference Pub Date : 2013-04-05 DOI: 10.1109/NEBEC.2013.56
A. Wren, A. Coughlan, K. Smale, S. Misture, B. Mahon, O. Clarkin, M. Towler
{"title":"Biocompatibility of CaO-Na2O-SiO2/TiO2 Glass Ceramic Scaffolds for Orthopaedic Applications","authors":"A. Wren, A. Coughlan, K. Smale, S. Misture, B. Mahon, O. Clarkin, M. Towler","doi":"10.1109/NEBEC.2013.56","DOIUrl":"https://doi.org/10.1109/NEBEC.2013.56","url":null,"abstract":"This work aims to determine the effect of substituting TiO<sub>2</sub>for SiO<sub>2</sub> in a 0.62SiO<sub>2</sub>-Na<sub>2</sub>O-0.24CaO based glass-ceramic scaffold. High temperature X-ray Diffraction (HT-XRD) was used to determine the sintering temperature (700°C). Both optical microscopy and x-ray micotomography was used to determine the average pore size (540-680μm) of each scaffold. Cytocompatibility of each scaffold was conducted using murine mesenchymal stem cells.","PeriodicalId":153112,"journal":{"name":"2013 39th Annual Northeast Bioengineering Conference","volume":"12 4","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2013-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"113971807","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Concurrent Multi-scale Imaging: Optical Coherence Tomography under MRI Guidance for Neurosurgery 并发多尺度成像:MRI指导下的神经外科光学相干断层扫描
2013 39th Annual Northeast Bioengineering Conference Pub Date : 2013-04-05 DOI: 10.1109/NEBEC.2013.164
I. Kim, Chia-Pin Liang, Bo Yang, G. Makris, J. Desai, R. Gullapalli, Yu Chen
{"title":"Concurrent Multi-scale Imaging: Optical Coherence Tomography under MRI Guidance for Neurosurgery","authors":"I. Kim, Chia-Pin Liang, Bo Yang, G. Makris, J. Desai, R. Gullapalli, Yu Chen","doi":"10.1109/NEBEC.2013.164","DOIUrl":"https://doi.org/10.1109/NEBEC.2013.164","url":null,"abstract":"We developed a novel platform based on a teleoperated robot to perform high-resolution optical coherence tomography (OCT) imaging under continuous MRI guidance. The combination of large-scale MRI tissue morphology and high-resolution OCT micro-architecture in a concurrent and co-registered manner has great potential to improve the accuracy of various neurosurgical procedures. In this study, we developed the first MRI-compatible OCT imaging system. We demonstrated that a thin OCT fiber probe (0.23 mm) integrated within surgical tools can provide microstructure information from the ROI under continuous MRI guidance. We tested the system's performance on chicken breast and simulated stereotactic neurosurgery on human brain ex vivo.","PeriodicalId":153112,"journal":{"name":"2013 39th Annual Northeast Bioengineering Conference","volume":"62 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2013-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115905133","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Computational Simulation of Shock Tube and the Effect of Shock Thickness on Strain-Rates 激波管的计算模拟及激波厚度对应变率的影响
2013 39th Annual Northeast Bioengineering Conference Pub Date : 2013-04-05 DOI: 10.1109/NEBEC.2013.69
K. Laksari, S. Assari, K. Darvish
{"title":"Computational Simulation of Shock Tube and the Effect of Shock Thickness on Strain-Rates","authors":"K. Laksari, S. Assari, K. Darvish","doi":"10.1109/NEBEC.2013.69","DOIUrl":"https://doi.org/10.1109/NEBEC.2013.69","url":null,"abstract":"Blast-induced neurotrauma has become an increasing concern with the advancement of explosive devices and high rates of loading. Recent experiments show that under blast loading conditions, brain tissue undergoes small displacements that are much lower than the threshold of traumatic brain injury. Based on the nonlinear viscoelastic nature of brain tissue, stress waves generated in the tissue due to blast loading can evolve into shock waves, which create high spatial and temporal pressure gradients at the shock front. In this study, the effect and importance of shock front thickness in simulating the response of tissues in shock tube scenarios has been investigated. It is shown that such measures can have a significant effect on prediction on injury in computational models.","PeriodicalId":153112,"journal":{"name":"2013 39th Annual Northeast Bioengineering Conference","volume":"68 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2013-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114914707","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
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