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2013 39th Annual Northeast Bioengineering Conference最新文献

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Calculation of Surface Electromygram Discharge Rate 表面肌电图放电率的计算
2013 39th Annual Northeast Bioengineering Conference Pub Date : 2013-04-05 DOI: 10.1109/NEBEC.2013.59
Lukai Liu, E. Clancy, P. Bonato
{"title":"Calculation of Surface Electromygram Discharge Rate","authors":"Lukai Liu, E. Clancy, P. Bonato","doi":"10.1109/NEBEC.2013.59","DOIUrl":"https://doi.org/10.1109/NEBEC.2013.59","url":null,"abstract":"The discharge rate of motor unit action potential sequences has been related to fatigue and neuromuscular diseases, but typically simple methods are used to do so. We adapted more advanced methods used to calculate heart rate to fit in the context of surface electromyogram discharge rate calculation. Simulation results with a deterministic discharge rate modulation model suggest that parameter fine-tuning is necessary to accurately and robustly estimate discharge rate.","PeriodicalId":153112,"journal":{"name":"2013 39th Annual Northeast Bioengineering Conference","volume":"126 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2013-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122959594","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Quantifying the Effect of Mechanical Vestibular Stimulation on Muscle Tone and Spasticity 量化机械前庭刺激对肌肉张力和痉挛的影响
2013 39th Annual Northeast Bioengineering Conference Pub Date : 2013-04-05 DOI: 10.1109/NEBEC.2013.131
G. Androwis, R. Foulds, A. Strongwater, D. Stone
{"title":"Quantifying the Effect of Mechanical Vestibular Stimulation on Muscle Tone and Spasticity","authors":"G. Androwis, R. Foulds, A. Strongwater, D. Stone","doi":"10.1109/NEBEC.2013.131","DOIUrl":"https://doi.org/10.1109/NEBEC.2013.131","url":null,"abstract":"The purpose of this pilot study is to determine whether mechanical stimulations to the otoliths would result in a change on the muscle tone on disabled subjects and to test the hypothesis of stimulating the otolith organs in the vestibular system and its effect on the muscle tone/spasticity in individuals with neuromotor disabilities, in addition to that is the importance of developing a deeper understanding of the process of vertical vestibular stimulation using a mechanical vestibular chair and to establish a clinical procedure that reduces spasticity in individuals with neuromotor disabilities. One spastic subject was tested and the muscle tone was evaluated using the \"(PKD Test)\".","PeriodicalId":153112,"journal":{"name":"2013 39th Annual Northeast Bioengineering Conference","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2013-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116227958","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
A Method to Reconnect Soft Tissue without Sutures 一种不需要缝合的软组织重新连接方法
2013 39th Annual Northeast Bioengineering Conference Pub Date : 2013-04-05 DOI: 10.1109/NEBEC.2013.41
T. Green, M. Barrientos, S. Luna, S. Marzouk, H. Wang
{"title":"A Method to Reconnect Soft Tissue without Sutures","authors":"T. Green, M. Barrientos, S. Luna, S. Marzouk, H. Wang","doi":"10.1109/NEBEC.2013.41","DOIUrl":"https://doi.org/10.1109/NEBEC.2013.41","url":null,"abstract":"Gastrointestinal problems account for 35% of the annual 176 million ambulatory visits with total costs approximately $1.7 billion in the past year. Currently, surgeries involving the small bowel require sutures, which lead to complications such as infection, cuts, leakage, tearing, and even bursting. We propose to reduce these complications and financial burden to $1.2 billion by using a newly designed Bioadhesive Bandage and Tissue Support to eliminate the need for sutures.","PeriodicalId":153112,"journal":{"name":"2013 39th Annual Northeast Bioengineering Conference","volume":"2006 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2013-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125840136","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Loss of Cement-Bone Interlock during In Vivo Service of Total Knee Replacements 全膝关节置换术中骨水泥联锁缺失
2013 39th Annual Northeast Bioengineering Conference Pub Date : 2013-04-05 DOI: 10.1109/NEBEC.2013.23
Jacklyn R. Goodheart, Mark A. Miller, K. Mann
{"title":"Loss of Cement-Bone Interlock during In Vivo Service of Total Knee Replacements","authors":"Jacklyn R. Goodheart, Mark A. Miller, K. Mann","doi":"10.1109/NEBEC.2013.23","DOIUrl":"https://doi.org/10.1109/NEBEC.2013.23","url":null,"abstract":"The morphology of the cement-bone interface from total knee replacements was investigated as a function of time in service. Ten post-mortem retrievals and one lab-prepared specimen were sectioned and imaged with high-resolution microscopy. Stereology was used to quantify contact fraction and interdigitation depth. The results show that loss of fixation occurs by resorption of trabeculae that interlock with cement. This occurs early after implantation (1-2 years). Donor bones with better initial interlock maintain interlock better in the short term. The results suggest that loss of interlock between cement and bone could be a factor contributing to aseptic loosening.","PeriodicalId":153112,"journal":{"name":"2013 39th Annual Northeast Bioengineering Conference","volume":"61 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2013-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125888262","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Characteristics of Auditory and Visual Elicited Saccades 听觉和视觉诱发性扫视的特征
2013 39th Annual Northeast Bioengineering Conference Pub Date : 2013-04-05 DOI: 10.1109/NEBEC.2013.63
Xiu Zhai, A. Ghahari, J. Enderle
{"title":"Characteristics of Auditory and Visual Elicited Saccades","authors":"Xiu Zhai, A. Ghahari, J. Enderle","doi":"10.1109/NEBEC.2013.63","DOIUrl":"https://doi.org/10.1109/NEBEC.2013.63","url":null,"abstract":"Saccadic eye movements in response to visual stimuli (V-saccade), auditory stimuli (A-saccade) and auditory-visual stimuli (AV-saccade) were recorded and analyzed. Human saccade data was collected using a SMI Hi-Speed eye tracking system and analyzed with a FORTRAN program, which was used to compute parameter estimates for a 1D saccadic eye movement model. Saccade characteristics were investigated, and the results of saccadic eye movements induced by the three different stimuli types were compared. The auditory-visual stimuli provided the greatest saccade accuracy. Peak velocity increased with increasing saccade amplitude as an exponential shape, while A-saccade showed lower values than V-saccade and AV-saccade. Duration was linearly proportional to saccade amplitude and it was longer for A-saccade. Latent period was relatively independent of saccade amplitude, but there was a significant reduction in AV-saccade.","PeriodicalId":153112,"journal":{"name":"2013 39th Annual Northeast Bioengineering Conference","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2013-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128240560","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Assessment of Changes in Engineered Cartilage Using Infrared Spectroscopy and Mechanical Analysis 利用红外光谱和力学分析评估工程软骨的变化
2013 39th Annual Northeast Bioengineering Conference Pub Date : 2013-04-05 DOI: 10.1109/NEBEC.2013.54
U. Palukuru, Michael Shockley, C. Mcgoverin, Padraig B. M. Glenn, N. Pleshko, Richard Spencer, E. Frank, A. Grodzinsky
{"title":"Assessment of Changes in Engineered Cartilage Using Infrared Spectroscopy and Mechanical Analysis","authors":"U. Palukuru, Michael Shockley, C. Mcgoverin, Padraig B. M. Glenn, N. Pleshko, Richard Spencer, E. Frank, A. Grodzinsky","doi":"10.1109/NEBEC.2013.54","DOIUrl":"https://doi.org/10.1109/NEBEC.2013.54","url":null,"abstract":"Myriad tissue engineering approaches have been proposed to produce engineered cartilage but the resulting tissues generally lack the strength of native cartilage. Suboptimal matrix production may account for the observed lack of strength. Fourier Transform Infrared Imaging Spectroscopy (FT-IRIS) was used to assess the compositional changes in engineered cartilage to further understand the role of matrix formation in mechanics of engineered cartilage.","PeriodicalId":153112,"journal":{"name":"2013 39th Annual Northeast Bioengineering Conference","volume":"74 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2013-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127355849","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Checking the Saliency of the Stimuli on Central versus Peripheral Visual Field 中央视野与周边视野刺激显著性的检验
2013 39th Annual Northeast Bioengineering Conference Pub Date : 2013-04-05 DOI: 10.1109/NEBEC.2013.66
Abhineet Mishra, Deniz Ozgulbas, E. Alay, Eun H. Kim, T. Alvarez
{"title":"Checking the Saliency of the Stimuli on Central versus Peripheral Visual Field","authors":"Abhineet Mishra, Deniz Ozgulbas, E. Alay, Eun H. Kim, T. Alvarez","doi":"10.1109/NEBEC.2013.66","DOIUrl":"https://doi.org/10.1109/NEBEC.2013.66","url":null,"abstract":"Saliency of the stimuli presumably plays a critical role in vision rehabilitation. This study sought to determine whether a peripheral or near central target influenced the peak velocity of convergence which may have an impact on visual saliency. Blue line stimuli, one without any distracting peripheral background and two with distracting background were given to four subjects within a haploscope setting. Eye movements were recorded with an infrared video camera system. Data were quantified using latency, amplitude, and peak velocity. Although a consistent decrease in peak velocity was observed statistical differences were not (p=0.13). The results suggest distraction does not significantly influence convergence step peak velocity. Future experiments include the study of other visual distracters.","PeriodicalId":153112,"journal":{"name":"2013 39th Annual Northeast Bioengineering Conference","volume":"44 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2013-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132046566","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Fabricating Consistently Sized Chitosan-Core NanoBioSensors
2013 39th Annual Northeast Bioengineering Conference Pub Date : 2013-04-05 DOI: 10.1109/NEBEC.2013.95
Khrystyna Dilai, K. E. Chambers, Danielle E. Clements, Patrick J. Bankich, C. J. Robinson
{"title":"Fabricating Consistently Sized Chitosan-Core NanoBioSensors","authors":"Khrystyna Dilai, K. E. Chambers, Danielle E. Clements, Patrick J. Bankich, C. J. Robinson","doi":"10.1109/NEBEC.2013.95","DOIUrl":"https://doi.org/10.1109/NEBEC.2013.95","url":null,"abstract":"Doubly labeled chitosan-TPP nanosensors provide a means of studying the effect of nitric oxide and glutamate excitotoxicity in the brain. In order to construct these nanosensors for use in vivo, it is necessary to develop a procedure that results in nanosensor cores of a consistent size. The goal of this project was to investigate various procedures and study the impact of solution temperature, pH, chitosan to TPP ratio, reagent concentration, sonication, and centrifugation on particle size. The optimal procedure involves combining aqueous chitosan and TPP in a 3:1 ratio and stirring at room temperature in 3.33% Acetic acid solution.","PeriodicalId":153112,"journal":{"name":"2013 39th Annual Northeast Bioengineering Conference","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2013-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130792029","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Spatial Variation in Aorta Composition and Correlation with Mechanical Properties 主动脉组成的空间变异及其与力学性能的相关性
2013 39th Annual Northeast Bioengineering Conference Pub Date : 2013-04-05 DOI: 10.1109/NEBEC.2013.140
A. Hemmasizadeh, R. Cheheltani, S. Assari, N. Pleshko, K. Darvish
{"title":"Spatial Variation in Aorta Composition and Correlation with Mechanical Properties","authors":"A. Hemmasizadeh, R. Cheheltani, S. Assari, N. Pleshko, K. Darvish","doi":"10.1109/NEBEC.2013.140","DOIUrl":"https://doi.org/10.1109/NEBEC.2013.140","url":null,"abstract":"Aorta is composed of distinct anatomical layers and components with different mechanical characteristics. Understanding and characterization of the interactions between aorta building blocks and their mechanical properties enable us to quantify changes that may occur in the material behavior of aorta as a result of cardiovascular diseases. In the present work the microstructural and components' heterogeneity along the porcine thoracic aorta wall thickness was studied with histology and infrared spectroscopy, and the changes were correlated to the mechanical properties along the wall thickness determined from nanoindentation tests. Two layers of equal thickness were distinguishable based on the radial variations in the instantaneous Young's modulus E, elastic lamellae density (ELD) as calculated from histology, and the total amount of protein as determined from infrared spectroscopy. The results showed that compared with the inner half, the outer half layer is stiffer, elastic lamellae are denser and total protein content is higher. ELD and total protein are strongly correlated with mechanical properties. It is likely that disruption of this balance has a major effect on cardiovascular health and disease.","PeriodicalId":153112,"journal":{"name":"2013 39th Annual Northeast Bioengineering Conference","volume":"15 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2013-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125212717","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation of Circumferential and Longitudinal Strain in a Rabbit Fetal Heart Model Using 4D Echocardiography 四维超声心动图评价兔胎心模型的周向和纵向应变
2013 39th Annual Northeast Bioengineering Conference Pub Date : 2013-04-05 DOI: 10.1109/NEBEC.2013.18
V. Apte, Lydia Tam, Angela Han, M. Zhu, M. Ashraf, D. Sahn, Zhijun Zhang
{"title":"Evaluation of Circumferential and Longitudinal Strain in a Rabbit Fetal Heart Model Using 4D Echocardiography","authors":"V. Apte, Lydia Tam, Angela Han, M. Zhu, M. Ashraf, D. Sahn, Zhijun Zhang","doi":"10.1109/NEBEC.2013.18","DOIUrl":"https://doi.org/10.1109/NEBEC.2013.18","url":null,"abstract":"Strain determination in fetal hearts is essential but conventional methods do not provide opportunities for orthogonal strain analysis and require the use of EKG-gating. A new non-gated 4D echocardiography method was tested for accuracy in strain computation. Fifteen rabbit hearts were studied. Each heart was mounted in a water tank to facilitate ultrasound scanning, connected to a calibrated pump by a balloon sutured into the left ventricle (LV), and pumped at Stroke Volumes (SV) 1-5 ml and Stroke Rates (SR) 40 and 80 bpm. Three 0.7mm sonomicrometry crystals were secured in the myocardium to conduct longitudinal strain (LS) and circumferential strain (CS) measurements. At each SV and each SR, 4D images were obtained by an X6-1 probe interfaced with the Philips iU-22 ultrasound system while sonomicrometry displacement was recorded. This process was performed pre and post simulated myocardial infarction (MI). 4D images were analyzed offline for strain by a MATLAB-based program. 4D echocardiography-derived strain data correlated with sonomicrometry-derived strain at each SV (CS: R2 = 0.91, p<;0.05; LS: R2 = 0.87, p<;0.05). A decrease in strain post-MI was detected by both echocardiography and sonomicrometry. Non-gated 4D echocardiography is an accurate method for strain determination of fetal hearts.","PeriodicalId":153112,"journal":{"name":"2013 39th Annual Northeast Bioengineering Conference","volume":"78 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2013-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116671020","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
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