利用红外光谱和力学分析评估工程软骨的变化

2013 39th Annual Northeast Bioengineering Conference Pub Date : 2013-04-05 DOI:10.1109/NEBEC.2013.54

U. Palukuru, Michael Shockley, C. Mcgoverin, Padraig B. M. Glenn, N. Pleshko, Richard Spencer, E. Frank, A. Grodzinsky

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引用次数: 0

摘要

无数组织工程方法已被提出，以产生工程化软骨，但所产生的组织通常缺乏天然软骨的强度。次优的矩阵生成可能是观察到的强度不足的原因。利用傅里叶变换红外成像光谱(FT-IRIS)技术评估工程软骨的成分变化，进一步了解基质形成在工程软骨力学中的作用。

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Assessment of Changes in Engineered Cartilage Using Infrared Spectroscopy and Mechanical Analysis

Myriad tissue engineering approaches have been proposed to produce engineered cartilage but the resulting tissues generally lack the strength of native cartilage. Suboptimal matrix production may account for the observed lack of strength. Fourier Transform Infrared Imaging Spectroscopy (FT-IRIS) was used to assess the compositional changes in engineered cartilage to further understand the role of matrix formation in mechanics of engineered cartilage.

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2013 39th Annual Northeast Bioengineering Conference

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