Journal of Biomaterials and Tissue Engineering最新文献

{"title":"pH Effects of Soda, Brew, and Citrus on Adhesive Bond Strength of Orthodontic Brackets to the Enamel. Scanning Electron Microscopy and Adhesive Remnant Index Analysis","authors":"H. Sultan, M. Kamran, S. Almoammar, M. A. Al Jearah, Mariam Khan, Syed Junaid Mahmood, Ghulam Ahmed, Mirza Mahmood","doi":"10.1166/jbt.2023.3287","DOIUrl":"https://doi.org/10.1166/jbt.2023.3287","url":null,"abstract":"Aim: To assess the effects of milk tea, carbonated drink, orange juice, and artificial saliva on the shear bond strength (SBS) of orthodontic brackets and assess their mode of failure under a scanning electron microscope (SEM). Material and Methods: Eighty non-carious\u0000 extracted premolars were disinfected, etched, had primer applied and cured, and bracket bonded with light cure composite adhesive. These teeth were then immersed in separate media of milk tea, carbonated drink, orange juice, and artificial saliva for 10 minutes per day for three months. After\u0000 which, they were thermocycled and subjected to shear stress in the Universal testing machine, and the shear load was recorded. Following debonding, the teeth were analyzed under SEM for failure analysis using adhesive remnant Index (ARI). Data were analyzed using ANOVA and Tukey multiple comparison\u0000 tests. Results: Carbonated drink and milk tea showed comparable shear bond strength which differed significantly from that of orange juice and artificial saliva. Conclusion: Carbonated drink had the most erosive effect on the tooth’s surface and showed the least shear bond\u0000 strength and adhesive remnant score than the teeth immersed in other media.","PeriodicalId":15300,"journal":{"name":"Journal of Biomaterials and Tissue Engineering","volume":" ","pages":""},"PeriodicalIF":0.1,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44532503","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An Efficient Investigation on Age-Related Macular Degeneration Using Deep Learning with Cloud-Based Teleophthalmology Architecture","authors":"P. Selvakumar, R. Arunprakash","doi":"10.1166/jbt.2023.3288","DOIUrl":"https://doi.org/10.1166/jbt.2023.3288","url":null,"abstract":"AMD, or age-related macular degeneration, is the fourth most common visual ailment leading to blindness worldwide and mostly affects persons over the age of 60. Early-stage blindness may be reduced with timely and precise screening. High-resolution analysis and identification of the\u0000 retinal layers damaged by illness is made possible by optical coherence tomography (OCT), a diagnostic technique. Setting up a comprehensive eye screening system to identify AMD is a difficult task. Manually sifting through OCT pictures for anomalies is a time-consuming and error-prone operation.\u0000 Automatic feature extraction from OCT images may speed up the diagnostic process and reduce the potential for human mistake. Historically, several methods have been developed to identify characteristics in OCT pictures. This thesis documents the development and evaluation of many such algorithms\u0000 for the identification of AMD. In order to minimize the severity of AMD, retinal fundus images must be employed for early detection and classification. In this work, we develop a useful deep learning cloud-based AMD categorization model for wearables. The suggested model is DLCTO-AMDC model,\u0000 a patient outfitted with a head-mounted camera (OphthoAI IoMT headset) may send retinaldehyde fundus imageries to a secure virtual server for analysis. The suggested AMD classification model employs Inception v3 as the feature extractor and a noise reduction approach based on midway point\u0000 filtering (MPF). The deep belief network (DBN) model is also used to detect and classify AMD. Then, an AOA-inspired hyperparameter optimisation method is used to fine-tune the DBN parameters. To ensure the DLCTO-AMDC model would provide superior classification results, extensive simulations\u0000 were done using the benchmark dataset. The findings prove the DLCTO-AMDC model is superior to other approaches already in use.","PeriodicalId":15300,"journal":{"name":"Journal of Biomaterials and Tissue Engineering","volume":" ","pages":""},"PeriodicalIF":0.1,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48585099","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Expression of S100A11 Gene in Stomach Adenocarcinoma and Its Relationship with Immune Cell Infiltration and Prognosis","authors":"Bao-Yin Zhang, Shuhao Wang, Linyuan Feng, J. Piao, Zhen-dong Lin, Yanqun Liu","doi":"10.1166/jbt.2023.3286","DOIUrl":"https://doi.org/10.1166/jbt.2023.3286","url":null,"abstract":"Stomach adenocarcinoma (STAD) is a complex biological process involving multiple factors. Given the importance of the immune-related tumor microenvironment (TME) in STAD, investigating tumor-immune interactions and identifying novel prognostic and therapeutic targets in STAD is a promising\u0000 avenue of research. S100A11 (S100 calcium-binding protein 11) is a class of proteins that transduces calcium-dependent cellular regulatory signals involved in cancer formation and development. Recent studies demonstrated that S100A gene families plays important roles in regulating immune cell\u0000 infiltration of cancers. However, the exact role of S100A11 in STAD has yet to be fully understood. Therefore, we examined S100A11 expression in STAD and its normal tissues using GEPIA and the Human Protein Atlas, using the UALCAN database was used to analyze the relationship between S100A11\u0000 protein expression and clinical parameters, and using the GSCA database was used to analyze the correlation between S100A11 protein expression and various subtypes of STAD. We found that S100A11 mRNA levels were significantly upregulated in STAD tissues compared to normal tissues. Elevated\u0000 S100A11 was significantly associated with poor overall survival (OS), first progression (FP) and post-progression survival (PPS) in multiple STAD patient populations.","PeriodicalId":15300,"journal":{"name":"Journal of Biomaterials and Tissue Engineering","volume":" ","pages":""},"PeriodicalIF":0.1,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41343308","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"CD5L is a Potential Biomarker for Clinical Prognosis and Immunotherapy of Hepatocellular Carcinoma","authors":"Bao-Yin Zhang, X. Ma, Zhen-dong Lin, Yanqun Liu","doi":"10.1166/jbt.2023.3283","DOIUrl":"https://doi.org/10.1166/jbt.2023.3283","url":null,"abstract":"The CD5L molecule (CD5L), also known as macrophage apoptosis inhibitor (AIM), has multiple functions in lipid metabolism and inflammatory processes. However, there is a lack of evaluation of CD5L in human tumors, especially its predictive role in HCC progression. The expression of CD5LmRNA\u0000 in patients with hepatocellular Carcinoma was searched by The Tumor Genome Atlas (TCGA) database. CD5L had significant protein interactions with FASN, CD163, STAB2, and LILRB5, which were retrieved by the timer database. The relationship between CD5L survival and prognosis in HCC and hepatitis\u0000 was analyzed by the KaplanMeier database. CD5L enrichment was analyzed by KEGG, Biological processes, Molecular functions, and Cellular components. CD5L expression was low in tumor tissues and high in neighboring tissues, showing a tumor inhibitory effect. Low expression of CD5L in patients\u0000 with hepatitis is associated with poor prognosis. TP53 mutations with low CD5L expression accounted for a high proportion of HCC. The high expression of CD5L promotes the infiltration of CD4+ T cells, CD8+ T cells, macrophages, Tfh, and other cells, causing an immune response. We comprehensively\u0000 evaluated the role of CD5L biomarkers in HCC, and CD5L may be a new target for tumor immunotherapy.","PeriodicalId":15300,"journal":{"name":"Journal of Biomaterials and Tissue Engineering","volume":" ","pages":""},"PeriodicalIF":0.1,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47145720","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of Different Applied Torque Maintenance Times on Detorque Values of Abutment Screws in Single Implant-Supported Fixed Prostheses","authors":"H. Alotaibi, Sarah Alnamlah, Rana M Almazroa, A. Alfouzan, S. Altaweel, H. Alshehri, N. Labban","doi":"10.1166/jbt.2023.3289","DOIUrl":"https://doi.org/10.1166/jbt.2023.3289","url":null,"abstract":"We evaluated the effect of maintaining the applied torque for one minute on the reverse torque value (RTV) as compared to immediate torque application and retorquing after 10 minutes. A total of 48 screws were used to torque the abutment utilizing three different protocols (A–C);\u0000 immediate torque application to the recommended 35 Ncm, torque applied to the recommended 35 Ncm, followed by retorquing of the same screw after 10 minutes and abutment screws were torqued to the recommended 35 Ncm, and the torque was held for one minute. The gap size between the implant and\u0000 supra-structure was measured at three fixed points for each surface. Data were analyzed using SPSS software (α = 0.05). The mean RTV for 1 minute, immediate, and 10 minutes was 32.68±2.04 Ncm, 32.5±0.93 Ncm, and 30.54±0.90 Ncm, respectively. The difference\u0000 between RTV in the 1-min and 10-min protocols was significant (P <0.05). Pearson’s coefficient demonstrated a negative correlation between RTV and the gap between the supra-structure and the implant interface (r =−0.43, P <0.01). When tightening abutment\u0000 screws of implant-supported single crowns, holding the applied torque for 1 minute has proven to be efficient. Furthermore, larger gap values between the supra-structure and the implant inversely affect RTV, forcing the clinician to take caution to have a well-fitted supra-structure with as\u0000 minimal a gap as possible.","PeriodicalId":15300,"journal":{"name":"Journal of Biomaterials and Tissue Engineering","volume":" ","pages":""},"PeriodicalIF":0.1,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46814303","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Inhibitory Effect of Metal Complexes Cisplatin and Carboplatin of Cervical Cancer Cells","authors":"Xiao-Jiao Nie, Huiru Cao, Wumidan Abudureheman, Chen Lin","doi":"10.1166/jbt.2023.3290","DOIUrl":"https://doi.org/10.1166/jbt.2023.3290","url":null,"abstract":"The recurrence and prognosis of advanced cervical cancer patients is an unresolved medical need. To improve prognosis and bring new strategies to more curable stages of the disease, such as high-risk locally advanced disease patients and low metastatic or small volume disease patients.\u0000 After culturing cervical cancer cells in vitro, they were treated with different concentrations of cisplatin and carboplatin drugs for 24, 48, and 72 hours respectively. Detected the inhibitory rate of different treatment groups on cervical cancer cells using CCK-8 detection, To observe\u0000 live and dead cells through staining experiments. The results showed that different concentrations of cisplatin and carboplatin have significant inhibitory effects on cervical cancer cells. However, the inhibitory effect of cisplatin and carboplatin in the high concentration group on cervical\u0000 cancer cells were significantly greater than that in the low concentration treatment group. The sensitivity of cervical cancer cells to cisplatin was similar with carboplatin, and the sensitivity to cisplatin was better than that of carboplatin. We believe that targeted therapy can be combined\u0000 with chemotherapy drugs to enhance the anti-tumor effect of cisplatin. When the toxic side effects of cisplatin cannot be overcome, carboplatin can be considered to replace cisplatin in the treatment of cancer.","PeriodicalId":15300,"journal":{"name":"Journal of Biomaterials and Tissue Engineering","volume":" ","pages":""},"PeriodicalIF":0.1,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47405065","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Preparation, Characterization and Osteoblastic Compatibility Evaluation of Bifunctional Polyvinyl Alcohol Hydrogels Containing RGD and Hyaluronic Acid","authors":"Yan Li, Lijie Sun, Lingli Zhou, Yonggang Ma, Mingyuan Liu","doi":"10.1166/jbt.2023.3279","DOIUrl":"https://doi.org/10.1166/jbt.2023.3279","url":null,"abstract":"In recent years, polyvinyl alcohol hydrogel has been repeatedly confronted with urgent needs for more enhanced bio-activity in the field of bone tissue engineering. We used sulfydryl-alkyne click chemical reaction to prepare a bifunctional polyvinyl alcohol hydrogel containing RGD peptide\u0000 and hyaluronic acid. Polyvinyl alcohol grafted with hyaluronic acid can reduce degradation rate and improve mechanical properties. RGD peptide can improve cell adhesion and migration on material surface. The bifunctional polyvinyl alcohol hydrogel is prepared by click chemistry reaction and\u0000 characterized by scanning electron microscopy, 1H NMR, Ellman’s test and Kjeldahl nitrogen determination. The physical properties of bifunctional polyvinyl alcohol hydrogel are evaluated in terms of tensile properties and water contact angle test. According to varying hydrogel\u0000 composition, five groups are designed to conduct the experiment as follows: Control group, PVA group, PVA-HA group, PVAPA-RGD group, and PVA-HA-SH/PVAPA-RGD group, each of which is to be co-cultured with MC3T3-E1 cells to observe cell morphology by laser scanning confocal microscope. Then,\u0000 CCK-8 method and cell counting method were used to detect the proliferation activity and cell adhesion rate, respectively. ALP activity and qRT-PCR were used to detect osteogenic differentiation and expression of osteogenic marker genes ALP, OCN, Runx2, Col I and OPN. The experimental results\u0000 show that the tensile strength of the bifunctional polyvinyl alcohol hydrogel is 1.42±0.61 MPa, with tensile modulus as 0.58±0.03 MPa, and elongation at break as 297.53±42.36%. The water contact angle is 18.40±2.2°. After three days of culture, the proliferation\u0000 activity ranks in order as PVA-HA-SH/PVAPA-RGD group > PVA-RGD group > PVA-HA group > PVA group > Control group. After 4 hours of culture, cell adhesion is sequenced as PVA-HA-SH/PVAPA-RGD group > bicomponent group > PVA group > Control group. After 48 hours of culture,\u0000 immunofluorescence staining demonstrates more sufficient cellular spreading and adherence, clearer actin fibers, more vinculin numbers in PVA-HA-SH/PVAPA-RGD group. In addition, significantly higher ALP activity (after 3 days’ culturing) and osteogenic gene expression level (after 7\u0000 days’ culturing) have been witnessed in PVA-HA-SH/PVAPA-RGD group than those of other groups. The overall experimental results have confirmed its excellent hydrophilicity and fine mechanical properties of the bifunctional polyvinyl alcohol hydrogel system, which would exert a remarkable\u0000 effect on proliferation, adhesion and osteogenic differentiation of MC3T3-E1 cells.","PeriodicalId":15300,"journal":{"name":"Journal of Biomaterials and Tissue Engineering","volume":" ","pages":""},"PeriodicalIF":0.1,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44329171","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Expression of Lymphoma-2 Gene and NF-κB in Human Adenoid Cystic Carcinoma Tissue and Its Relation with Disease Prognosis","authors":"Dongtao Wang, Yu Yang, Tianyong Zhao, Fang Wang, Jingrui Qi, Lu Sui, L. Xing","doi":"10.1166/jbt.2023.3267","DOIUrl":"https://doi.org/10.1166/jbt.2023.3267","url":null,"abstract":"Background: Adenoid cystic carcinoma (ACC) is a common tumor of the head and neck. It is characterized by slow growth, strong invasiveness, easy recurrence and distant organ metastasis. Bcl-2 and NF-κB are indicated to relate to tumor growth, proliferation and apoptosis.\u0000 This study aims to analyze the relationship between Bcl-2, NF-κB and ACC. Methods: With ELISA method to detect Bcl-2 and NF-κB expression in the blood of patients with ACC, patients with benign adenoma and healthy controls, and the expression of Bcl-2 and NF-κB\u0000 in tissues was detected by immunohistochemistry, and their relationship with ACC was analyzed. relevance. Relationships between clinicopathological features. Results: The levels of Bcl-2 (4.16±1.34 ng/ml) and NF-κB (4.47 ± 1.37 ng/ml) as well as positive rates\u0000 of Bcl-2 and NF-κB (87.5% and 85%) were significantly elevated in the ACC group (P <0.05). Bcl-2 was positively correlated with NF-κB (P <0.05). Of note, Bcl-2 and NF-κB expressions were correlated with the incidence frequency, histological\u0000 type, clinical stage, lymph node metastasis and distant metastasis of ACC patients (P < 0.05) as the distant metastasis is an independent risk factor. Conclusion: In summary, Bcl-2 and NF-κB expression in ACC patients is associated with the clinicopathological\u0000 features of ACC.","PeriodicalId":15300,"journal":{"name":"Journal of Biomaterials and Tissue Engineering","volume":" ","pages":""},"PeriodicalIF":0.1,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46177394","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of Diamond Rotary Instruments Advertised for Cutting 3Y-TZP Restorations. A Scanning Electron Microscope Analysis","authors":"A. Alqahtani, A. AlHelal, A. Alayad, A. Alotaibi, Fahad A. Alfarraj, Omar S. Alosaimi, Ziyad H. Alharbi","doi":"10.1166/jbt.2023.3274","DOIUrl":"https://doi.org/10.1166/jbt.2023.3274","url":null,"abstract":"Aim: To examine the cutting efficiency and amount of material removed from crown-cutting diamond burs from a different manufacturer on zirconia using an electric handpiece. Material and Methods: The performance of super coarse diamond bur round-end from five different\u0000 manufacturers that were commercially advertised as zirconium crown cutters were assessed. The five manufacturers and their respective diamond bur models tested were super coarse Group 1: Dimond bur, Group 2: Zirconia Diamond Bur, Round End Cylinder, Meisinger, Group 3: 4ZR Zirconia Cutter\u0000 Diamond Crown Removal Bur, Group 4: Brasseler Dental Diamond Bur, Group 5: Expanded SS White® Lineup of Zirconia Cutting Diamonds. The qualitative assessment of diamond burs (before zirconia cutting) and (after zirconia cutting) was assessed using a scanning electron microscope.\u0000 The mean cutting distance and material removed for each group were calculated and analyzed using one-way ANOVA. Results: The highest cutting efficiency was found in group 2 and the lowest efficiency was observed in group 5. Post-SEM images of rotary zirconia cutting instruments in groups\u0000 (Post G1-G5) demonstrate pullout, wear, chipping, and loss of the diamond grains in general. Conclusion: Zirconia Diamond Bur (G2) was found to be suitable. Whereas, (G5) Expanded SS White® Lineup of Zirconia Cutting Great White®Z Diamonds is less effective.","PeriodicalId":15300,"journal":{"name":"Journal of Biomaterials and Tissue Engineering","volume":" ","pages":""},"PeriodicalIF":0.1,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44605023","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Gastric Disorder Analysis Using Hybrid Optimization with Machine Learning","authors":"G. Gurumoorthy, S. Ganesh Vaidyanathan","doi":"10.1166/jbt.2023.3269","DOIUrl":"https://doi.org/10.1166/jbt.2023.3269","url":null,"abstract":"The stomach and all of its appendages, which include the oesophagus, duodenum, small intestine, and large intestine, amongst others, all play a crucial function within this system. Stomach dysrhythmias, which are linked to problems with the movement of gastrointestinal contents, affect\u0000 a significant number of individuals all over the globe. These problems include inappropriate digestion (dyspepsia), nausea (vomiting sensation) for no apparent reason, vomiting, abdominal pain, stomach ulcers, gastroesophageal reflux disease, and other disorders. During the process of finding\u0000 the anomalies, it is possible that a number of techniques, including as imaging, endoscopy, electrogastrogram, and clinical analysis, will be used. Electrogastrography signals, also known as electrogastrograms (EGG), were captured using surface Ag/AgCl electrodes that were put over the stomach\u0000 in 20 healthy persons before the data was gathered and pre-processed. The datasets were produced from these signals (8 Females and 12 Males). In addition to this, the datasets were obtained from 10 individuals who were suffering from various stomach illnesses (3 Females and 8 Males). In the\u0000 stage known as “pre-processing,” which needs the obtained dataset to be treated in advance, any noise that was present in the signal is removed. In order to rid the data of any noise and increase the overall quality of the input data, a technique that is known as the Wiener filter\u0000 is used. A technique known as Hybrid Grey Wolf Optimization with Particle Swarm Optimization is utilized in the process of feature selection. This algorithm is responsible for removing any extraneous data from the features that have been collected from the signal. The procedure is sped up\u0000 as a result of this. The classifiers get the qualities that have been chosen as their input in order to carry out an analysis of the many stomach disorders, such as primary gastric lymphoma, gastrointestinal stromal tumour (GIST), and neuroendocrine tumor. This enables the classifiers to do\u0000 the analysis (carcinoid). The Multi-class Feed Forward Neural Network Classifier (MCFFN) is used to carry out the classification process. This classifier provides the stages along with the classes. The accuracy, sensitivity, and specificity of the classification process are taken into account\u0000 in the calculation of performance measures.","PeriodicalId":15300,"journal":{"name":"Journal of Biomaterials and Tissue Engineering","volume":" ","pages":""},"PeriodicalIF":0.1,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48469451","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}