Journal of Cancer Survivorship最新文献

{"title":"Fertility in breast cancer survivorship: a scoping review.","authors":"Sanjna Rajput, Elizabeth J Cathcart-Rake, Kathryn J Ruddy, Chandra C Paff Shenoy, Christine Connors, Dame Idossa","doi":"10.1007/s11764-026-02111-4","DOIUrl":"https://doi.org/10.1007/s11764-026-02111-4","url":null,"abstract":"<p><strong>Purpose: </strong>To summarize current evidence on fertility issues in breast cancer survivors, including gonadotoxic potential of cancer-directed therapies, available fertility preservation options, counseling practices, post-treatment pregnancy outcomes, and future research needs. This review aims to guide clinical practice and to highlight current gaps in oncofertility care.</p><p><strong>Methods: </strong>A critical review of recent literature was conducted, consolidating data from clinical trials, cohort studies, guidelines, and expert consensus. Key themes in oncofertility care for breast cancer survivors were mapped through the breadth of literature, including therapy-associated gonadotoxicity, fertility preservation strategies, multidisciplinary care models, and post-treatment reproductive outcomes.</p><p><strong>Results: </strong>Breast cancer-directed therapies (chemotherapy, long-term endocrine therapy, targeted therapies) can adversely impact fertility via delaying reproductive timelines and direct gonadotoxicity. Oocyte and embryo cryopreservation are first-line methods for fertility preservation; other options include ovarian tissue cryopreservation and ovarian suppression with gonadotropin-releasing hormone (GnRH) agonist administration. Pregnancy after stage 0-3 breast cancer is considered safe, with no evidence of increased recurrence or mortality risk even among those with hormonally sensitive cancers. Fertility counseling and ovarian toxicity assessment remain inconsistently implemented in clinical trials. In addition, barriers to fertility care disproportionately affect historically excluded populations.</p><p><strong>Conclusions: </strong>Oncofertility is a crucial element of survivorship care for reproductive-aged patients with breast cancer. Cancer-directed therapies can significantly impair the likelihood of future fertility. Early, structured fertility counseling, multidisciplinary care team collaboration including reproductive endocrinology, and incorporation of timely fertility preservation interventions are vital to maintain fertility potential without harming oncologic outcomes. Major gaps remain in counseling practices and equitable access to fertility preservation.</p><p><strong>Implications for cancer survivors: </strong>Enhanced access to fertility preservation, individualized reproductive planning, and multidisciplinary care teams can improve quality of life and support informed decision-making regarding future childbearing in breast cancer survivors.</p>","PeriodicalId":15284,"journal":{"name":"Journal of Cancer Survivorship","volume":" ","pages":""},"PeriodicalIF":3.4,"publicationDate":"2026-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148857234","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Patterns of sexual dysfunction among breast cancer survivors five years after diagnosis: a latent class analysis of the French VICAN5 study.","authors":"Eqbal Radwan, Lorène Seguin, Magali Provansal, Julien Mancini, Anne-Déborah Bouhnik","doi":"10.1007/s11764-026-02108-z","DOIUrl":"https://doi.org/10.1007/s11764-026-02108-z","url":null,"abstract":"<p><strong>Purpose: </strong>Sexual health concerns are highly prevalent among breast cancer survivors. Sexual dysfunction can occur from various causes, including the cancer itself, treatment side effects, and psychological distress. Therefore, this study aimed to identify distinct patterns of sexual dysfunction among women in remission from breast cancer 5 years after diagnosis using latent class analysis (LCA) and to examine factors associated with higher sexual dysfunction classes.</p><p><strong>Methods: </strong>We conducted a cross-sectional secondary analysis of data from 356 women participating in the French nationwide VICAN5 survey 5 years after breast cancer diagnosis. Sexual dysfunction was assessed using five selected items from the Relationship and Sexuality Scale (RSS), and LCA was applied to these indicators to identify distinct dysfunction patterns. Ordinal logistic regression was used to examine factors associated with higher sexual dysfunction classes.</p><p><strong>Results: </strong>A three-class model best fit the data, identifying no/low (n = 124, 34.8%), moderate (n = 133, 37.4%), and high (n = 99, 27.8%) sexual dysfunction classes. Older age at diagnosis (>50 years) (aOR, 2.30; 95% CI, 1.34-3.97; p = 0.003), frequent alcohol consumption (aOR, 2.00; 95% CI, 1.05-3.84; p = 0.036), radiotherapy (aOR, 2.36; 95% CI, 1.21-4.61; p = 0.012), current adjuvant endocrine therapy use (aOR, 1.87; 95% CI, 1.14-3.06; p = 0.013), frequent excessive sweating (aOR, 1.67; 95% CI, 1.01-2.77; p = 0.047), frequent paresthesia in the breast/arm (aOR, 1.78; 95% CI, 1.07-2.95; p = 0.026), hypnotic use (aOR, 1.66; 95% CI, 1.09-2.53; p = 0.018), and feeling less sexually attractive (aOR, 4.72; 95% CI, 3.01-7.41; p < 0.001) were associated with higher odds of being in a higher sexual dysfunction class.</p><p><strong>Conclusions: </strong>Sexual dysfunction remained common 5 years after breast cancer diagnosis, with more than one-quarter of survivors having high sexual dysfunction. These results suggest that the assessment of sexual health should be incorporated into survivorship care for breast cancer, especially in women experiencing issues with body image and persistent treatment symptoms.</p><p><strong>Implications for cancer survivors: </strong>Sexual health should be integrated into survivorship care, including oncosexual consultations, psychosexual support for body image concerns, and management of persistent treatment-related symptoms.</p>","PeriodicalId":15284,"journal":{"name":"Journal of Cancer Survivorship","volume":" ","pages":""},"PeriodicalIF":3.4,"publicationDate":"2026-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148857283","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Benefits of prehabilitative exercise on physiological, functional and patient-reported outcomes in patients undergoing oncologic surgery: A systematic review and meta-analysis.","authors":"Natália Casagrande, Favil Singh, Anderson Rech, Régis Radaelli, Bruna M Paniz, Guilherme T Silvestro, Guilherme N Eberhardt, Janaína Brollo, Maximiliano C Kneubil, Claudio P Júnior, Pedro W M de Almeida, Maria Cristina F Magalhães, Francesco Bettariga, Pedro Lopez","doi":"10.1007/s11764-026-02107-0","DOIUrl":"https://doi.org/10.1007/s11764-026-02107-0","url":null,"abstract":"<p><strong>Purpose: </strong>Prehabilitation, delivered between cancer diagnosis and surgery, may enhance functional reserve and improve tolerance to surgical stress, but evidence remains conflicting across cancer types and outcomes. We aimed to evaluate the effects of prehabilitative exercise on physiological, functional, and patient-reported outcomes in patients undergoing oncologic surgery.</p><p><strong>Methods: </strong>A systematic review and meta-analysis was conducted (PROSPERO: CRD420251072796). Randomized controlled trials comparing structured exercise interventions with usual care in adults undergoing oncologic surgery were included. Searches were performed across seven databases until June 2025. Outcomes included cardiorespiratory fitness, muscle strength, physical function, fatigue, psychological distress, and quality of life. A three-level mixed-effects meta-analysis evaluated intervention effects and moderators.</p><p><strong>Results: </strong>Twenty-seven studies (n = 2005) were included. Prehabilitation significantly improved cardiorespiratory fitness (SMD 0.31, p = 0.010), physical function (SMD 0.36, p < 0.001), and quality of life (SMD 0.19, p = 0.030), with sustained postoperative benefits in physical function. Fatigue was reduced preoperatively (SMD -0.21, p = 0.017), while muscle strength and psychological distress were preserved relative to baseline. Certainty of evidence ranged from very low to moderate.</p><p><strong>Conclusions: </strong>Prehabilitative exercise improves preoperative fitness, function, fatigue, and quality of life, and attenuates perioperative decline in patients undergoing cancer surgery. These findings support integrating structured exercise into perioperative oncology pathways to optimise recovery and long-term outcomes.</p><p><strong>Implications for cancer survivors: </strong>Prehabilitative exercise may mitigate perioperative deconditioning and facilitates a return to baseline function. By potentially preserving functional reserve against surgical stress, these interventions could contribute to improved long-term survivorship trajectories and should be considered within structured, individualised perioperative care pathways.</p>","PeriodicalId":15284,"journal":{"name":"Journal of Cancer Survivorship","volume":" ","pages":""},"PeriodicalIF":3.4,"publicationDate":"2026-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148857237","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction: Support needs of young people caring for their parents with cancer.","authors":"Janet Njelesani, Lindsey Kaufman, Sienna Ruiz, Victoria Leigh Brown, Jean Hunleth","doi":"10.1007/s11764-026-02072-8","DOIUrl":"10.1007/s11764-026-02072-8","url":null,"abstract":"","PeriodicalId":15284,"journal":{"name":"Journal of Cancer Survivorship","volume":" ","pages":""},"PeriodicalIF":3.4,"publicationDate":"2026-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148840417","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"It's hard enough having cancer as an adolescent or young adult, but what about its financial impact?","authors":"Samantha Watson","doi":"10.1007/s11764-026-02089-z","DOIUrl":"https://doi.org/10.1007/s11764-026-02089-z","url":null,"abstract":"<p><p>The financial challenges of the author as a young adult were discussed. These costs were further made worse because of a second cancer diagnosis and treatment only a few years later. The health matters and their economic burden occurred while in college, which also presented a significant cost. This \"survivor perspective\" also goes on to describe a valuable resource for financial toxicity developed by the author as a way to truly pay it forward: The SAMFund (now part of Expect Miracles Foundation). The author describes the financial strain of other young adult cancer survivors who actually received funding from her organization. Samantha then discusses a \"second wave\" of costs that go beyond the acute costs of treatment. These are the persistent costs related to cancer survivorship. This 25-year cancer survivor provides a personal perspective on the long-term financial impact of cancer in those with a history of cancer as an adolescent or young adult.</p>","PeriodicalId":15284,"journal":{"name":"Journal of Cancer Survivorship","volume":" ","pages":""},"PeriodicalIF":3.4,"publicationDate":"2026-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148793567","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Subsequent oncology visits among cancer survivors transitioned to primary care: a retrospective cohort study.","authors":"Francine S Fishbein, Daryl Bainbridge, Som D Mukherjee, Elizabeth Vadacchino, Russell Leong, Jonathan Sussman","doi":"10.1007/s11764-026-02105-2","DOIUrl":"https://doi.org/10.1007/s11764-026-02105-2","url":null,"abstract":"<p><strong>Purpose: </strong>There is increasing focus on transitioning cancer survivors from oncology to primary care, yet little is known about why some patients return to oncology following transition. We aimed to describe the reasons for and outcomes of subsequent oncology visits among cancer survivors transitioned to primary care.</p><p><strong>Methods: </strong>We conducted a retrospective cohort study of patients transitioned to primary care at the Juravinski Cancer Centre. We analyzed all patients transitioned to primary care from 2013 to 2020. A chart review was completed for transitioned patients with subsequent oncology visits to determine the reasons for return and subsequent investigations/treatments.</p><p><strong>Results: </strong>Among 2604 transitioned cancer survivors, 440 (16.9%) had a subsequent oncology visit. One-third were not true re-referrals but rather visits for genetic counseling, clinical trials, or palliative care follow-up (32.7%). Apart from these, the most common reasons for visit were investigation of symptoms (32.7%) or tests (23.2%). Recurrence or new disease was detected in 28.2% of those with a subsequent visit, representing 4.8% of all transitioned patients. Most of these patients went on to receive treatment.</p><p><strong>Conclusions: </strong>Only a small proportion of transitioned patients were referred back to oncology, and recurrence was detected in a small fraction of the overall cohort, supporting the safety of primary care led survivorship. Patients were seen for many reasons and were readily able to reconnect with oncology regardless of underlying pathology. Implications for Cancer Survivors Transitioning cancer survivors to primary care appears safe, with low recurrence rates and the ability to readily reaccess oncology care when needed.</p>","PeriodicalId":15284,"journal":{"name":"Journal of Cancer Survivorship","volume":" ","pages":""},"PeriodicalIF":3.4,"publicationDate":"2026-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148793712","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Subsequent malignant neoplasm among cancer survivors in the United States.","authors":"Emily S Tonorezos, Theresa P Devasia, Lisa Gallicchio, Michelle A Mollica, Michelle Doose, Eduardo J Santiago-Rodríguez, Angela Mariotto","doi":"10.1007/s11764-026-02102-5","DOIUrl":"https://doi.org/10.1007/s11764-026-02102-5","url":null,"abstract":"<p><strong>Background: </strong>One of the most significant events following a diagnosis of cancer is the diagnosis of subsequent malignant neoplasm (SMN). Estimates of the number and risk of more than one malignancy in this population are needed.</p><p><strong>Methods: </strong>Utilizing data from 1975 to 2021 from the National Cancer Institute's Surveillance, Epidemiology, and End Results (SEER) Program, estimates of the number, proportion, and standardized incidence ratios (SIRs) of survivors with SMN by age at diagnosis, time since diagnosis, and primary site were calculated.</p><p><strong>Results: </strong>As of January 1, 2022, the estimated number of cancer survivors in the US with one malignancy was 14,940,581, while 2,191,482 survivors had two malignancies. A smaller number of survivors (379,897) had three malignancies; 110,859 people had four or more malignancies. Compared to people who never had cancer, cancer survivors had an increased risk of SMN (SIR, 1.19; 95% CI, 1.19 to 1.19). Survivors diagnosed with the first malignancy before age 40 were at highest risk of SMN (SIR, 1.78; 95% CI, 1.76 to 1.81). Among all cancer survivors, 15.2% had an SMN, with the highest percentage of survivors with SMN observed among those with a history of melanoma, bladder cancer, or Hodgkin lymphoma.</p><p><strong>Conclusion: </strong>More than 2.5 million cancer survivors in the US have had two or more malignancies, representing 15% of the US cancer survivor population. The risk of SMN is notable for those diagnosed at a younger age and with certain types of first malignancies.</p><p><strong>Implications for cancer survivors: </strong>About 15% of cancer survivors in the United States have had more than one malignancy.</p>","PeriodicalId":15284,"journal":{"name":"Journal of Cancer Survivorship","volume":" ","pages":""},"PeriodicalIF":3.4,"publicationDate":"2026-08-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148793562","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Beyond income: financial hardship as a pathway from socioeconomic disadvantage to depression among middle and older cancer survivors.","authors":"Meiyan Chen, Lailea Noel, Anao Zhang","doi":"10.1007/s11764-026-02103-4","DOIUrl":"https://doi.org/10.1007/s11764-026-02103-4","url":null,"abstract":"<p><strong>Background: </strong>Depression disproportionately affects older cancer survivors with fewer socioeconomic resources, yet the mechanisms underlying this disparity remain under-explored. Guided by Fundamental Cause Theory, this study examined whether financial hardship mediates the relationship between socioeconomic status (SES) indicators, education, income, and wealth, and depressive symptoms among older cancer survivors in the United States.</p><p><strong>Methods: </strong>Data were drawn from the Health and Retirement Study (2012-2018). The analytic sample comprised 1,520 cancer survivors aged 50 and older. A seven-item latent financial hardship variable was developed. Structural equation modeling with weighted least squares estimation was employed under a complex survey design to test direct and indirect effects of SES indicators on subsequent depressive symptoms through financial hardship, controlling for demographic, health, and cancer-related characteristics.</p><p><strong>Results: </strong>The measurement model demonstrated excellent fit (CFI = .997; TLI = .995; RMSEA = .031). In the structural model, income and wealth were fully mediated by financial hardship in their associations with depression, while education exhibited partial mediation with both direct and indirect pathways. Younger age at cancer diagnosis and more recent diagnoses were significantly associated with greater financial hardship. Financial hardship was a significant predictor of subsequent de-pressive symptoms (β = 0.213, p < .001), and the model explained 36.2% of the variance in depression.</p><p><strong>Conclusions and implications: </strong>Financial hardship operates as a critical intermediary mechanism linking socioeconomic disadvantage to depression among older cancer survivors, suggesting that interventions targeting financial hardship may help reduce mental health disparities in this population.</p><p><strong>Implications for cancer survivors: </strong>These findings indicate that the emotional toll of socioeconomic disadvantage operates largely through the concrete experience of financial hardship, such as difficulty affording necessities, medical costs, and other material demands. Because financial hardship is more immediately modifiable than underlying socioeconomic position, it offers a practical point of intervention. Routine screening for financial hardship in survivorship care, coupled with referral to financial navigation, benefits counseling, and cost-of-care support services, may help identify survivors at elevated risk of depression who might otherwise go unrecognized. Our findings further suggest that survivors relying on Medicare without supplemental coverage may warrant particular attention, as gaps in coverage can expose them to financial strain that income alone does not capture. Addressing material hardship may thus represent a concrete avenue for reducing socioeconomic disparities in mental health among older survivors.</p>","PeriodicalId":15284,"journal":{"name":"Journal of Cancer Survivorship","volume":" ","pages":""},"PeriodicalIF":3.4,"publicationDate":"2026-08-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148760242","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence and associated factors of poor lifestyle behaviours in survivors of childhood cancer: a PanCareFollowUp substudy.","authors":"Selina R van den Oever, Leontien C M Kremer, Helena J H van der Pal, Mieke Rijken, Gisela Michel, Andrea Beccaria, Eline Bouwman, Jeroen Te Dorsthorst, Samira Essiaf, Elizabeth Lieke A M Feijen, Cecilia Follin, Line Elmerdahl Frederiksen, Hannah Gsell, Maria van Helvoirt, Rosella P M G Hermens, Lars Hjorth, Tomas Kepak, Katerina Kepakova, Anita Kienesberger, Marietta Kokla, Monica Muraca, Kylie O'Brien, Marleen Renard, Katharina Roser, Carina Schneider, Roderick Skinner, Ramona Tallone, Anne Uyttebroeck, Deveny Vanrusselt, Sabine Verschueren, Jeanette Falck Winther, Jacqueline Loonen, Saskia M F Pluijm","doi":"10.1007/s11764-026-02099-x","DOIUrl":"https://doi.org/10.1007/s11764-026-02099-x","url":null,"abstract":"<p><strong>Purpose: </strong>Poor lifestyle behaviours may contribute to the development or worsening of late effects after childhood cancer. The aims of this study were to determine the baseline prevalence and associated factors of poor lifestyle behaviours among childhood cancer survivors of the European PanCareFollowUp study cohort.</p><p><strong>Methods: </strong>In Belgium, Sweden, Czechia, and Italy, 812 childhood cancer survivors were recruited. Outcomes were self-reported poor lifestyle behaviours, defined as low physical activity (<75 min of vigorous or <150 min of moderate to vigorous physical activity per week), current smoking (yes/no), alcohol consumption (≥3 units of alcohol per week), and drug use in the past year (yes/no). The prevalence of poor lifestyle behaviours was calculated and associations with sociodemographic characteristics, cancer history, physical health, pain, fatigue, and survivors' level of empowerment were estimated using multivariable logistic regression analyses.</p><p><strong>Results: </strong>For these analyses, 777 participants were included, of whom 27% of survivors reported low physical activity, 15% smoked, 19% consumed ≥3 units of alcohol per week, and 9% used drugs in the past year. The smoking prevalence differed per country and was highest among survivors from Czechia (23%) and Italy (22%) and lowest in Belgium (10%) and Sweden (5%). Associated factors with any of the four poor lifestyle behaviours included male sex, lower educational attainment, reduced physical health, pain, and fatigue.</p><p><strong>Conclusions: </strong>Study results show that survivors in each of the four countries may benefit from personalised interventions to promote healthier behaviours, and that reduced physical health, pain, and fatigue may present modifiable targets.</p><p><strong>Implications for cancer survivors: </strong>These findings can be used to develop targeted lifestyle interventions, thereby optimising survivors' lifestyle behaviours, health outcomes, and quality of life.</p>","PeriodicalId":15284,"journal":{"name":"Journal of Cancer Survivorship","volume":" ","pages":""},"PeriodicalIF":3.4,"publicationDate":"2026-08-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148793590","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effect of health behaviour interventions on alcohol consumption among people living with cancer: a systematic review.","authors":"Manuela Beaty, Wei-Hong Liu, Patsy Yates, Kim Alexander","doi":"10.1007/s11764-026-02065-7","DOIUrl":"https://doi.org/10.1007/s11764-026-02065-7","url":null,"abstract":"<p><strong>Purpose: </strong>This systematic review synthesises data relating to the effectiveness of behavioural interventions aimed at reducing alcohol consumption among people living with cancer.</p><p><strong>Methods: </strong>Five databases were systematically searched for randomised controlled trials (RCTs) published between January 2000 and April 2025 that reported behavioural interventions addressing alcohol consumption among people living with cancer. Evidence was assessed using the Cochrane Risk-of-Bias tool. Meta-analysis was not feasible due to substantial heterogeneity and few eligible studies. Instead, a TIDieR-guided narrative synthesis with vote-counting was performed. We conducted this systematic review according to the PRISMA 2020 statement.</p><p><strong>Results: </strong>Eight RCTs (n = 1437) were included. Two trials targeted alcohol reduction, whereas the remaining six addressed alcohol use within broader multiple health-behaviour interventions. Alcohol intake was assessed via self-report using heterogeneous measures. At 2-3 months, all five reporting studies favoured the intervention (100%, 95% CI 57-100%; p = 0.063). At 5-6 months, 57% of seven studies indicated benefit (95% CI 25-84%; p = 0.125), and 67% of three studies favoured the intervention (95% CI 21-94%; p = 0.500) at 12 months. All studies were rated as having unclear or high risk of bias. These vote-counting results should be interpreted cautiously, as effect-direction methods do not confirm the presence or magnitude of a true intervention effect.</p><p><strong>Conclusions: </strong>Heterogeneity was substantial across the studies. There is insufficient evidence that health behaviour interventions effectively reduce alcohol consumption among people living with cancer.</p><p><strong>Implications for cancer survivors: </strong>Further research should explore the behavioural mechanisms driving alcohol use among people living with cancer and prioritise the development of alcohol-specific interventions tailored to their unique needs.</p><p><strong>Trial registration: </strong>PROSPERO (registration number CRD42023456578).</p>","PeriodicalId":15284,"journal":{"name":"Journal of Cancer Survivorship","volume":" ","pages":""},"PeriodicalIF":3.4,"publicationDate":"2026-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148761351","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}