Journal of Cancer Survivorship最新文献

{"title":"Effect of exercise based on the ACSM recommendations on fatigue in patients with digestive tumors: a meta-analysis of randomized controlled trials.","authors":"Meng Liang, Zheng Liu, Rui Zhang, Nan Zhang","doi":"10.1007/s11764-025-01780-x","DOIUrl":"https://doi.org/10.1007/s11764-025-01780-x","url":null,"abstract":"<p><strong>Objective: </strong>Fatigue is the most common side effect in cancer and cancer treatment. This study aimed to investigate the effect of different amounts of exercise on fatigue in patients with digestive tumors.</p><p><strong>Methods: </strong>We searched articles published to March 2024 in the PubMed, Embase, Web of Science, and Cochrane databases. The amount of exercise was evaluated according to the American College of Sports Medicine (ACSM) and divided into high compliance and low compliance. The effect of compliance on fatigue in patients with digestive tumors was compared using standardized mean difference and 95% confidence intervals (95% CI).</p><p><strong>Results: </strong>A total of 18 articles were included, and we found that exercise had beneficial effects on cancer-related fatigue (CRF) in patients with digestive tumors. Fifteen studies that met the ACSM recommendations were grouped eventually. Eight studies were classified as high compliance and 7 studies as low compliance. The CRF was improved significantly in the high compliance (- 1.89; 95% [CI], - 2.93 to - 0.86) compared with the low compliance (- 1.43; 95% [CI], - 2.25 to - 0.61).</p><p><strong>Conclusion: </strong>Exercise intervention with high compliance showed a more significant improvement in fatigue in patients with digestive tumors compared with low compliance. However, these studies have not yet been fully uniform for the scoring tool for CRF, and further studies are needed to validate these findings.</p><p><strong>Implications for cancer survivors: </strong>Compared with low compliance, exercise intervention with high compliance has shown a more significant improvement in fatigue among patients with digestive tumors. In addition, the beneficial effects of high compliance with exercise intervention on fatigue in patients with digestive tumors also provide important implications for cancer survivors. Regular exercise that conforms to the American College of Sports Medicine (ACSM) recommendations, especially maintaining high compliance, can serve as an effective strategy to alleviate cancer-related fatigue and improve the quality of life of survivors. However, these studies have not yet been fully unified in the scoring tools for cancer-related fatigue (CRF), and further research is needed to validate these findings.</p>","PeriodicalId":15284,"journal":{"name":"Journal of Cancer Survivorship","volume":" ","pages":""},"PeriodicalIF":3.1,"publicationDate":"2025-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143780240","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of different mind-body exercises on quality of life and cancer-related fatigue in breast cancer survivors: a systematic review and network meta-analysis.","authors":"Peng Pi, Liqing Zeng, Qinghui Han, Bing Han, Yan Wang","doi":"10.1007/s11764-025-01766-9","DOIUrl":"https://doi.org/10.1007/s11764-025-01766-9","url":null,"abstract":"<p><strong>Purpose: </strong>To compare the efficacy of the different mind-body exercises (MBEs) for quality of life (QOL) and cancer-related fatigue (CRF) in women breast cancer (BC) survivors.</p><p><strong>Methods: </strong>This review searched published randomized controlled trials (RCTs) in eight electronic databases: PubMed, Web of Science, Embase, Cochrane CENTRAL, EBSCO, CNKI, VIP, and WanFang from inception to October 30, 2023. NMA and comparative effects ranking were performed using STATA 17.0 software.</p><p><strong>Results: </strong>This study included 121 studies with 11,072 women BC patients and eight different MBEs. Baduanjin showed the largest effect size in significantly improving subjective QOL (SMD = 3.03, 95% CI (2.04, 4.01)) compared with the control group, followed by relaxation training (SMD = 1.44, 95% CI (1.04, 1.85)), yoga (SMD = 0.89, 95% CI (0.36, 1.42)), mindfulness (SMD = 0.83, 95% CI (0.54, 1.12)), and Tai chi (SMD = 0.76, 95% CI (0.04, 1.48)). Furthermore, Tai chi (SMD =  - 1.42, 95% CI (- 2.21, - 0.63)) ranked first in significantly reducing CRF in BC patients compared with the control group, followed by mindfulness (SMD =  - 0.81, 95% CI (- 1.11, - 0.50)), relaxation training (SMD =  - 0.70, 95% CI (- 1.12, - 0.28)), and yoga (SMD =  - 0.53, 95% CI (- 0.88, - 0.18)).</p><p><strong>Conclusions: </strong>Baduanjin and Tai chi are the most effective MBEs for improving QOL and CRF in female BC survivors, respectively. We recommend that healthcare providers prioritize Baduanjin and Tai chi as complementary therapies for BC survivors.</p><p><strong>Implications for cancer survivors: </strong>Baduanjin and Tai chi have significant effects on improving the QOL of breast cancer patients and alleviating CRF, which is worthy of promotion and application.</p>","PeriodicalId":15284,"journal":{"name":"Journal of Cancer Survivorship","volume":" ","pages":""},"PeriodicalIF":3.1,"publicationDate":"2025-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143772200","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Perception of infertility risk vs. objective fertility status in males exposed to alkylating agents but not radiation therapy: a report from the St. Jude Lifetime (SJLIFE) cohort study.","authors":"Megan E Ware, Raymond K We, William H Kutteh, Rachel T Webster, Angela Delaney, Christine Yu, Kyla Shelton, DeoKumar Srivastava, Siddhant Taneja, Yadav Sapkota, Zhaoming Wang, Melissa M Hudson, John Lucas, Gregory T Armstrong, Kirsten K Ness, Daniel M Green","doi":"10.1007/s11764-025-01793-6","DOIUrl":"https://doi.org/10.1007/s11764-025-01793-6","url":null,"abstract":"<p><strong>Purpose: </strong>This study aimed to characterize associations between male childhood cancer survivors' perception of infertility risk and objective fertility status and to identify factors contributing to risk perception.</p><p><strong>Methods: </strong>Participants were from SJLIFE, exposed to alkylating agents but not radiation, and completed a Men's Health Questionnaire (MHQ) and semen analysis. Samples were obtained following the 2010 World Health Organization Guidelines, and classified as azoospermic (0 sperm), oligospermic (> 0 and < 15 million sperm/ml), or normospermic (≥ 15 million sperm/ml). Participants were classified as at minimally or high/significantly increased risk for infertility according to the Pediatric Initiative Network (PIN) criteria. Perception of infertility risk was assessed via self-report where survivors indicated the following: (1) more risk than peers without cancer history, (2) less risk, or (3) equal risk, as well as factors contextualizing perceived risk. Chi-squared tests or Fishers' exact tests assessed differences in variables of interest.</p><p><strong>Results: </strong>Among 238 participants (age 27 ± 6 years, 85% NH White, 47% survivors of leukemia), 58% perceived increased infertility risk than peers without cancer history, 29% equal risk, and 13% less risk. A larger proportion of survivors with azoospermia perceived higher risk than other groups (74%) (p = 0.01). No differences were observed in risk perception by PIN criteria. No differences were observed by sperm concentration category or PIN criteria in factors contextualizing perceived risk.</p><p><strong>Conclusions: </strong>Male survivors not exposed to radiation in the SJLIFE cohort are generally aware of their infertility risk.</p><p><strong>Implications for cancer survivors: </strong>Male survivors should seek continued follow-up care regarding fertility and information on risk from reputable sources.</p>","PeriodicalId":15284,"journal":{"name":"Journal of Cancer Survivorship","volume":" ","pages":""},"PeriodicalIF":3.1,"publicationDate":"2025-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143763839","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An exploration of testicular cancer survivors' experience of ejaculatory dysfunction following retroperitoneal lymph node dissection-a sub-study of the PREPARE clinical trial.","authors":"C Conduit, A D Hutchinson, M Leonard, S O 'Haire, M Moody, B Thomas, I Sim, W Hong, G Ahmad, N Lawrentschuk, J Lewin, B Tran, H M Dhillon","doi":"10.1007/s11764-023-01489-9","DOIUrl":"10.1007/s11764-023-01489-9","url":null,"abstract":"<p><strong>Purpose: </strong>Ejaculatory dysfunction secondary to retrograde ejaculation or anejaculation is a complication of retroperitoneal lymph node dissection (RPLND) for survivors of testicular cancer. We explored survivors' experiences of ejaculatory dysfunction following RPLND.</p><p><strong>Methods: </strong>In a sub-study of a single-arm phase 2 clinical trial (ACTRN12622000537752/12622000542796), participants reporting ejaculatory dysfunction ≥ 6 months following RPLND were invited to complete semi-structured interviews. Purposive sampling was used. Interviews continued until thematic saturation occurred, and codebook thematic analysis of interviews was performed.</p><p><strong>Results: </strong>Of 58 individuals recruited to the trial, 33 (57%) reported ejaculatory dysfunction. Of these, 32 (97%) agreed to interview and 15 participated. Participants interviewed had median age 34 years (range 24-66), 12 (80%) in a long-term relationship with median time from surgery 36 months (range 11-112). Three overarching themes were identified. The first reflected the value of RPLND despite ejaculatory dysfunction. The second illuminated the impact(s) of ejaculatory dysfunction closely mapped to life stage, with flow-on impacts to fertility, sex, psychological wellbeing and communication. The third reflected information needs. Fertility was a substantial source of concern for some participants. Ejaculatory dysfunction had no effect on sex for some, whilst for others, sex was less pleasurable. Some reported benefits. Few reported ejaculatory dysfunction challenged masculinity, confidence, or self-esteem.</p><p><strong>Conclusions: </strong>Future research should examine interventions to reduce distress related to fertility, challenged masculinity and body image.</p><p><strong>Implications for cancer survivors: </strong>Whilst most participants considered ejaculatory dysfunction to have little impact on their sexual function and relationships, some reported significant difficulties varying by life stage and relationship status.</p>","PeriodicalId":15284,"journal":{"name":"Journal of Cancer Survivorship","volume":" ","pages":"558-567"},"PeriodicalIF":3.1,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138047051","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Socioeconomic differences in health-related quality of life among cancer survivors and comparison with a cancer-free population: a PROFILES study.","authors":"Anne Katrine Graudal Levinsen, Lonneke van de Poll-Franse, Nicole Ezendam, Mieke J Aarts, Trille Kristina Kjaer, Susanne Oksbjerg Dalton, Simone Oerlemans","doi":"10.1007/s11764-023-01494-y","DOIUrl":"10.1007/s11764-023-01494-y","url":null,"abstract":"<p><strong>Purpose: </strong>This study investigates the association between socioeconomic position (SEP) and health-related quality of life (HRQoL) in a cross-sectional cohort among cancer survivors and compares with cancer-free people.</p><p><strong>Methods: </strong>Survivors of colorectal, hematological, gynecological, prostate, thyroid cancer, and melanoma diagnosed 2000-2014 were identified in the PROFILES registry, and an age- and sex-matched cancer-free population were identified in the CentER panel. HRQoL, education, and comorbidity were self-reported. Street-level income and clinical factors were obtained from Statistics Netherlands and the Netherlands Cancer Registry. Multivariable logistic regression was used to examine associations of SEP (measured by education and income) and impaired HRQoL among cancer survivors and the cancer-free population, adjusting for age, sex, and time since diagnosis.</p><p><strong>Results: </strong>We included 6693 cancer survivors and 565 cancer-free people. Cancer survivors with low versus medium SEP more frequently reported impaired HRQoL (odds ratio (OR) range for all HRQoL outcomes, 1.06-1.78 for short education and 0.94-1.56 for low income). Survivors with high compared to medium SEP reported impaired HRQoL less frequently (OR range for all HRQoL outcomes, 0.46-0.81 for short education and 0.60-0.84 for low income). The association between SEP and HRQoL was similar in the matched cancer-free population.</p><p><strong>Conclusion: </strong>Low SEP was associated with impaired HRQoL in both cancer survivors and cancer-free people.</p><p><strong>Implications for cancer survivors: </strong>Targeted care is warranted for cancer survivors with impaired HRQoL, especially among those with low SEP.</p>","PeriodicalId":15284,"journal":{"name":"Journal of Cancer Survivorship","volume":" ","pages":"614-622"},"PeriodicalIF":3.1,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138451570","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"\"Care needs to be integrated\" Patient and provider perspectives on a cancer shared-care model.","authors":"Shoshana Adler Jaffe, Miria Kano, Stephanie Rieder, Amy C Gundelach, Tawny Boyce, Teresa Rutledge, Zoneddy Dayao, Andrew L Sussman","doi":"10.1007/s11764-023-01486-y","DOIUrl":"10.1007/s11764-023-01486-y","url":null,"abstract":"<p><strong>Purpose: </strong>Current early-stage breast and gynecological cancer care models often begin with a referral from a primary care provider (PCP) or gynecologist (OB/Gyn) and end with a patient being transitioned back to the referring provider at the completion of treatment. There is frequently little communication between oncologists and the referring provider during treatment, and this pattern continues after the patient completes their treatment.</p><p><strong>Methods: </strong>We convened a diverse Patient Advisory Board (PAB) to identify areas where breast or gynecological cancer patients felt they could benefit from additional support during and after their cancer care. PAB members attended five Zoom meetings and completed four online surveys. Semi-structured interviews were conducted with primary care or OB/Gyn physicians to collect information on current practices.</p><p><strong>Results: </strong>Patients identified multiple areas in which they needed additional support from their PCP. Providers also identified topics on which they could use additional training. However, there was little overlap between patient and provider priority topics. Both patients and providers agreed that there was inadequate communication between the cancer center and PCPs before, during, and after cancer treatment.</p><p><strong>Conclusions: </strong>A shared-care model that emphasizes communication between primary care providers, the oncology care team, and patients is urgently needed. Patients indicated the need for additional support from their PCP on specific topics, and PCPs were interested in continuing their education to better serve their patients with cancer.</p><p><strong>Implications for cancer survivors: </strong>The importance of consistent communication among all parties during the entire cancer journey was emphasized as a key area for improvement.</p>","PeriodicalId":15284,"journal":{"name":"Journal of Cancer Survivorship","volume":" ","pages":"526-533"},"PeriodicalIF":3.1,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"54229214","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Children with cancer and their cardiorespiratory fitness and physical function-the long-term effects of a physical activity program during treatment: a multicenter non-randomized controlled trial.","authors":"Martin Kaj Fridh, Peter Schmidt-Andersen, Liv Andrés-Jensen, Troels Thorsteinsson, Peder Skov Wehner, Henrik Hasle, Kjeld Schmiegelow, Hanne Bækgaard Larsen","doi":"10.1007/s11764-023-01499-7","DOIUrl":"10.1007/s11764-023-01499-7","url":null,"abstract":"<p><strong>Purpose: </strong>We aimed to determine the effects of a classmate-supported, supervised, in-hospital physical activity program during treatment primarily on cardiorespiratory fitness and secondarily on physical function.</p><p><strong>Methods: </strong>A multicenter non-randomized controlled intervention study including children diagnosed with cancer, 6-18 years at diagnosis treated with chemo-/radiotherapy. The intervention comprised (i) an educational session on cancer in the child's school class; (ii) selection of two \"ambassadors\"-classmates who were co-admitted, supporting the child's everyday hospital life; and (iii) supervised in-hospital physical activity from diagnosis and throughout intensive treatment. One-year post-treatment, physical testing included cardiorespiratory fitness (primary outcome), Sit-to-Stand test, Timed-Up-and-Go, and Handgrip Strength.</p><p><strong>Results: </strong>The intervention group included 75 of 120 children (61% boys, 13.4 ± 3.1 years); the control groups included 33 of 58 children with cancer (58% boys, 13.5 ± 2.5 years), and 94 age- and sex-matched children without a cancer history. One-year post-treatment, cardiorespiratory fitness tended to be higher in the intervention group (37.0 ± 6.0 mL/kg/min) than in the patient control group with cancer (32.3 ± 9.7 mL/kg/min) (mean difference 4.7 [0.4 to 9.1], p = 0.034). The intervention group performed better in the secondary outcomes. Compared with community controls, both patient groups had lower cardiorespiratory fitness. The patient control group had lower Sit-to-Stand, Timed Up and Go, and Handgrip Strength, while the intervention group had strength comparable to that of the community controls.</p><p><strong>Conclusions: </strong>Peer-supported, supervised, in-hospital physical activity during treatment may improve cardiorespiratory fitness and muscle strength 1-year post-treatment in children with cancer; however, survivors continue to have lower cardiorespiratory fitness than community controls.</p><p><strong>Implications for cancer survivors: </strong>Children with cancer may benefit from in-hospital physical activity in improving long-term cardiorespiratory fitness and muscle strength.</p>","PeriodicalId":15284,"journal":{"name":"Journal of Cancer Survivorship","volume":" ","pages":"672-684"},"PeriodicalIF":3.1,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11926049/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138498521","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Breast cancer survivors' experiences of barriers and facilitators to lymphedema self-management behaviors: a theory-based qualitative study.","authors":"Aomei Shen, Peipei Wu, Wanmin Qiang, Fei Zhu, Zijuan Zhang, Ying Wang, Qian Lu","doi":"10.1007/s11764-023-01497-9","DOIUrl":"10.1007/s11764-023-01497-9","url":null,"abstract":"<p><strong>Purpose: </strong>Lifelong self-management plays a critical role in the prevention and management of lymphedema among breast cancer survivors. However, adherence to lymphedema self-management behaviors has remained suboptimal. Hence, we adopted a theory-informed method to elucidate the facilitators and barriers of lymphedema self-management for breast cancer survivors.</p><p><strong>Methods: </strong>In-depth semi-structured interviews were conducted between August and October 2022 in the lymphedema nursing clinic of a tertiary cancer hospital. The maximum variation sampling technique was used to ensure a diverse sample. The ITHBC (Integrated Theory of Health Behavior Change) framework was used to inform the interview outline and data analysis. Interview transcripts were coded line-by-line and mapped to domains in accordance with the ITHBC, using both deductive and inductive content analysis.</p><p><strong>Results: </strong>A total of 16 participants were interviewed (aged 35 to 67). Twenty-three themes (12 facilitators and 11 barriers) were mapped onto the three domains (knowledge and belief, social facilitation, and self-regulation skill and ability) of ITHBC as facilitators and barriers to lymphedema self-management. Three additional themes including limited treatment resources for lymphedema, inconvenience of lymphedema management, boredom and tedium of lymphedema self-management were categorized under the domain of other barriers.</p><p><strong>Conclusions: </strong>Incorporating these findings into the ITHBC framework allows for a more systematic selection of theory-based strategies that may improve the design of effective lymphedema self-management interventions for breast cancer survivors.</p><p><strong>Implications for cancer survivors: </strong>Elucidating impact factors, especially facilitators and barriers, for lymphedema self-management adherence is essential for developing effective intervention programs to enhance breast cancer survivors' lymphedema self-management behaviors.</p>","PeriodicalId":15284,"journal":{"name":"Journal of Cancer Survivorship","volume":" ","pages":"642-658"},"PeriodicalIF":3.1,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136397547","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Barriers and facilitators to the implementation of a new European eHealth solution (SurPass v2.0): the PanCareSurPass Open Space study.","authors":"Ismay A E de Beijer, Emma C Hardijzer, Riccardo Haupt, Desiree Grabow, Julia Balaguer, Edit Bardi, Adela Cañete Nieto, Audronė Ciesiūniene, Vanessa Düster, Anna-Liesa Filbert, Hannah Gsell, Monika Kapitančukė, Ruth Ladenstein, Thorsten Langer, Monica Muraca, Selina R van den Oever, Sofie Prikken, Jelena Rascon, Maria Teresa Tormo, Anne Uyttebroeck, Gertrui Vercruysse, Helena J H van der Pal, Leontien C M Kremer, Saskia M F Pluijm","doi":"10.1007/s11764-023-01498-8","DOIUrl":"10.1007/s11764-023-01498-8","url":null,"abstract":"<p><strong>Purpose: </strong>To identify barriers and facilitators for implementing the Survivorship Passport (SurPass) v2.0 in six long-term follow-up (LTFU) care centres in Europe.</p><p><strong>Methods: </strong>Stakeholders including childhood cancer survivors (CCSs), healthcare providers (HCPs), managers, information and technology (IT) specialists, and others, participated in six online Open Space meetings. Topics related to Care, Ethical, Legal, Social, Economic, and Information & IT-related aspects of implementing SurPass were evaluated.</p><p><strong>Results: </strong>The study identified 115 barriers and 159 facilitators. The main barriers included the lack of standardised LTFU care in centres and network cooperation, uncertainty about SurPass accessibility, and uncertainty about how to integrate SurPass into electronic health information systems. The main facilitators included standardised and coordinated LTFU care in centres, allowing CCSs to conceal sensitive information in SurPass and (semi)automatic data transfer and filing.</p><p><strong>Conclusions: </strong>Key barriers to SurPass implementation were identified in the areas of care, ethical considerations, and information & IT. To address these barriers and facilitate the implementation on SurPass, we have formulated 27 recommendations. Key recommendations include using the internationally developed protocols and guidelines to implement LTFU care, making clear decisions about which parties have access to SurPass data in accordance with CCSs, and facilitating (semi)automated data transfer and filing using Health Level 7 (HL7) Fast Healthcare Interoperability Resources (FHIR).</p><p><strong>Implications for cancer survivors: </strong>The findings of this study can help to implement SurPass and to ensure that cancer survivors receive high-quality LTFU care with access to the necessary information to manage their health effectively.</p>","PeriodicalId":15284,"journal":{"name":"Journal of Cancer Survivorship","volume":" ","pages":"659-671"},"PeriodicalIF":3.1,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11926050/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138444822","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sleep quality and physical fitness as modifiable contributors of fatigue in childhood cancer survivors.","authors":"Deveny Vanrusselt, Charlotte Sleurs, Nel Van Ermengem, Astrid Torrekens, Jurgen Lemiere, Sabine Verschueren, Anne Uyttebroeck","doi":"10.1007/s11764-024-01741-w","DOIUrl":"10.1007/s11764-024-01741-w","url":null,"abstract":"<p><strong>Purpose: </strong>Advances in cancer treatment have increased childhood cancer patient's survival rates. However, many childhood cancer survivors (CCS) face long-term effects such as fatigue. This study assessed fatigue in CCS and healthy controls (HCs), its contributors, and associated outcomes.</p><p><strong>Methods: </strong>This cross-sectional study included 90 CCS and 55 age and sex-matched HCs. Fatigue was measured using the Pediatric Quality of Life Multidimensional Fatigue Scale, and modifiable contributors included sleep quality (Pittsburgh Sleep Quality Index [PSQI]) and physical fitness (VO₂ peak during a treadmill test). Quality of life (QoL) and emotional and cognitive functioning were evaluated using the Pediatric Quality of Life Inventory, Beck Depression Inventory II, Cognitive Failure Questionnaire, and the Impact of Event Scale-Revised. Stepwise linear regressions identified predictors of general, sleep/rest, cognitive, and total fatigue.</p><p><strong>Results: </strong>General, cognitive, and total fatigue were significantly higher in CCS compared to HCs (44.7% vs. 23%, p < .001; cognitive: 64.7% vs. 29.3%, p < .001; total fatigue: 56.5% vs. 25%, p < .001). Sex, PSQI, PSQI × sex, and PSQI × VO₂ were significant predictors for general fatigue, PSQI and PSQI × VO₂ for cognitive fatigue, and PSQI for sleep/rest and total fatigue. Cognitive and total fatigue correlated most strongly with cognitive and work-related functioning, whereas general and sleep/rest fatigue were more related to psychosocial functioning.</p><p><strong>Conclusion: </strong>Fatigue is highly prevalent among CCS, with distinct factors influencing general, sleep/rest, cognitive, and total fatigue. Female survivors, those with poorer sleep quality and lower physical fitness, are at risk.</p><p><strong>Implications for cancer survivors: </strong>This study underscores the need for tailored interventions for each type of fatigue. Improving sleep quality, physical fitness, and psychological well-being may contribute to reducing fatigue and enhancing overall quality of life in CCS.</p>","PeriodicalId":15284,"journal":{"name":"Journal of Cancer Survivorship","volume":" ","pages":"728-741"},"PeriodicalIF":3.1,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143006119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}