Journal of Biosensors and Bioelectronics最新文献

{"title":"Photonic Crystals for Malaria Detection","authors":"S. Bendib, C. Bendib","doi":"10.4172/2155-6210.1000257","DOIUrl":"https://doi.org/10.4172/2155-6210.1000257","url":null,"abstract":"Cell refractive index is a key biophysical parameter, which has been extensively studied. Healthy red blood cells have a homogeneous distribution in refractive index, while infected red blood cells in malaria disease show non-homogeneous refractive index throughout the cytoplasm of the cell. In this paper we design and simulate a 2D photonic crystal ring resonator based refractive index biosensor for malaria detection. The simulation results have analyzed by using the finite difference time domain (FDTD) method, the band gap calculation is performed using the plane wave expansion method. The grating design, incorporated in the photonic crystal waveguide increases the efficiency and sensitivity of the designed sensor. risk of blood-borne disease transmission, and is uncomfortable for the patient [8]. Optical techniques are revolutionizing the way in which biological questions can be addressed directly in the living cell. The optical techniques that inform on the changes in mechanical properties during the infection cycle. Their sensitivity, specificity and non-intrusiveness make optical techniques indispensable to generate high-fidelity data, significantly improving the tools available to future research into blood disease [7]. Photonic crystal based biosensor is one of this optical techniques. Photonic biosensor are presents early diagnostic tool and provide a superior sensitivity, reliability, stability, fast response in vivo and vitro diagnostics [9]. In this paper we design and simulate a 2D photonic crystal biosensor. Where the biosensor chip is filled by blood sample and according their refractive index transmission is deliberated. The ‘PWE band solver’ of the software package OPTIFDTD is used to investigate the band gap of 2D rectangular PCs with GaAs rodes distributed in air wafer and its relationship with the refractive index of blood samples filled in order to improve the sensitivity. The Structure By creating point defects or cavity or by changing the size of each rod causes defect which act as a resonator. The optical resonator is also designed by creating some defects into the structure which breaks the periodicity of structure and also localized the light. Another type of optical resonator is designed by creating ring resonator [10]. We choose a ring resonator because the sensitivity is derived from the long photon lifetime inside the cavity. It provides high field localization, which increases the interaction between the light and the matter, that’s why the sensitivity increases also, for this reason we choose to implement a ring resonator in our design. Citation: Bendib S, Bendib C (2018) Photonic Crystals for Malaria Detection. J Biosens Bioelectron 9: 257. doi: 10.4172/2155-6210.1000257","PeriodicalId":15247,"journal":{"name":"Journal of Biosensors and Bioelectronics","volume":"6 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75818901","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mathematical Model for Laboratory System of Bioluminescent Whole-Cell Biosensor with Optical Element","authors":"H. Kalábová, M. Pospíšilová, M. Jiřina, G. Kuncová","doi":"10.4172/2155-6210.1000250","DOIUrl":"https://doi.org/10.4172/2155-6210.1000250","url":null,"abstract":"The fiber-optic biosensor with encapsuled bioreporters use a special optical element (OE) from pure silica with an active layer contents bioluminescent bioreporters was developed as a real in-situ detector for on-line measurement in remote localities. The active layer of biosensor contents bioluminescent bioreporters – genetic modified cells, which are sensitive to its surrounding environment-immobilized in silica matrix on the end of OE. Bioreporters are able to react by emission of visible light (≈500 nm) – bioluminiscence reaction (BL) – in presence of specific analyte. The genetic modified bacterial stain Pseudomonas putida TVA8 was chosen as biorecognition part of biosensor producing BL in the presence of benzene, toluene, ethylbenzene and xylens (BTEX). Very low level of BL signal was detected by high-sensitive photon-counter. The sensitivity of biosensor depends on a value of detected BL and it can be very low. The signal is also affected by number of cells (light sources) immobilized into the active layer and transmission through OE. Mathematical model of OE shape was developed based on geometric optics. The numerical model is built around the MATLAB scripting language. Simulation of ray transmission was calculated for OE with different shape.","PeriodicalId":15247,"journal":{"name":"Journal of Biosensors and Bioelectronics","volume":"40 1","pages":"1-5"},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82648553","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Wireless Charging of Implantable Pacemaker’s Battery","authors":"B. Patel","doi":"10.4172/2155-6210.1000258","DOIUrl":"https://doi.org/10.4172/2155-6210.1000258","url":null,"abstract":"","PeriodicalId":15247,"journal":{"name":"Journal of Biosensors and Bioelectronics","volume":"75 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83863411","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Silicon Carbide Biotechnology for Robust Implantable Neural Interfaces","authors":"pStephen E Saddowp","doi":"10.4172/2155-6210-C3-041","DOIUrl":"https://doi.org/10.4172/2155-6210-C3-041","url":null,"abstract":"","PeriodicalId":15247,"journal":{"name":"Journal of Biosensors and Bioelectronics","volume":"16 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72894495","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A New Tool for the Detection of Horsemeat Adulteration in Raw Meat","authors":"R. Faria, H. Iden, E. Bharucha, Lins Vfc, Y. Messaddeq, T. Matencio, Heneine Lgd","doi":"10.4172/2155-6210.1000264","DOIUrl":"https://doi.org/10.4172/2155-6210.1000264","url":null,"abstract":"","PeriodicalId":15247,"journal":{"name":"Journal of Biosensors and Bioelectronics","volume":"14 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89306332","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Production design and generation of a whole-cell optic biosensor Huh7-1X-ARE-luc","authors":"Nazanin Rahimi-Rad, Saeedeh Kavousi","doi":"10.4172/2155-6210-C3-043","DOIUrl":"https://doi.org/10.4172/2155-6210-C3-043","url":null,"abstract":"","PeriodicalId":15247,"journal":{"name":"Journal of Biosensors and Bioelectronics","volume":"3 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88717120","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Real Medical Data Processing and Prediction of Early Disease Using Sensors, Internet of Things (IoT) and R Programming Techniques","authors":"Pavan Hvs, P. Maruti, Viswanadh Nr, Puhazholi","doi":"10.4172/2155-6210.1000254","DOIUrl":"https://doi.org/10.4172/2155-6210.1000254","url":null,"abstract":"With the recognition of wearable devices, along with the development of clouds and cloudlet technology, there has been increasing got to give higher treatment. The process chain of medical knowledge chiefly includes knowledge assortment, data storage and knowledge sharing, etc. ancient tending system often needs the delivery of medical knowledge to the cloud, which involves users sensitive info and causes communication energy consumption much, medical knowledge sharing could be a vital and difficult issue therefore during this paper, we tend to build up a completely unique healthcare system by utilizing the exibility of cloudlet. The functions of cloudlet embody privacy protection, knowledge sharing and intrusion detection within the stage of information assortment, we RST utilize range Theory analysis Unit (NTRU) methodology to encrypt users body knowledge collected by wearable devices. Firstly, those data are going to be transmitted to close cloudlet in AN energy efficient fashion. Secondly, we tend to gift a replacement trust model to assist users to select trustable partners UN agency need to share hold on knowledge in the cloudlet. The trust model conjointly helps similar patients to communicate with one another concerning their diseases. Thirdly, we divide users medical knowledge hold on in remote cloud of hospital into 3 elements, and provides them correct protection. Finally, in order to guard the tending system from malicious attacks, we develop a completely unique cooperative intrusion detection system (IDS) method supported cloudlet mesh, which may effectively forestall the remote tending massive knowledge cloud from attacks. Our experiments demonstrate the effectiveness of the projected theme. Index terms privacy protection, knowledge sharing, cooperative intrusion detection system (IDS), healthcare.","PeriodicalId":15247,"journal":{"name":"Journal of Biosensors and Bioelectronics","volume":"44 47","pages":"1-4"},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91468634","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Design and Development of ECG Simulator and Microcontroller Based Displayer","authors":"H. Shirzadfar, M. Khanahmadi","doi":"10.4172/2155-6210.1000256","DOIUrl":"https://doi.org/10.4172/2155-6210.1000256","url":null,"abstract":"Cardiovascular disease is one of the major causes of mortality among developed societies. Therefore, an Electrocardiograph (ECG) device is one of the most important diagnostic devices in the medical field. Using this device, can be record and analyse electrical waves created in the heart and treat and treat cardiovascular disease. An ECG recorded electrocardiogram contains P wave, PR interval, QRS complex, ST segment, T wave, QT interval and U wave. Any changes in the ECG chart represent a type of cardiovascular disease. Using the ECG simulator, can be simulate the vital signal of the human heart and use it to inspect the correct functioning of the ECG device. Due to the fact that all medical devices are directly related to the patient, they should be checked for safety and accuracy, so that there is no risk to the patient and no problem to the diagnosis of heart disease. This article examines the Manufacture of an ECG simulator with an LCD (liquid-crystal display) that can display heart signals using this simulator.","PeriodicalId":15247,"journal":{"name":"Journal of Biosensors and Bioelectronics","volume":"9 1","pages":"1-9"},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78423353","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Direct, label-free and rapid transistor-based immunodetection in whole serum","authors":"Óscar Gutiérrez‐Sanz","doi":"10.4172/2155-6210-C1-035","DOIUrl":"https://doi.org/10.4172/2155-6210-C1-035","url":null,"abstract":"","PeriodicalId":15247,"journal":{"name":"Journal of Biosensors and Bioelectronics","volume":"138 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77531355","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Review on digitalization of basic routine procedures in histopathology laboratories","authors":"N. T. Omorodion, P. Achukwu, Godfrey Innocent Iyare, Ajanwachuku Ogbonna Wilson","doi":"10.15406/ijbsbe.2017.03.00085","DOIUrl":"https://doi.org/10.15406/ijbsbe.2017.03.00085","url":null,"abstract":"Digitalization is the process of converting of analog to digital. Slowly but surely, healthcare is going digital. Many of the recent innovations in healthcare, from telemedicine and smart devices to the growing capabilities in managing big data, can be traced back to the adoption of new digital technologies that have fostered a different way of working. Across medicine’s varied specialty areas, however, the adoption and progress of digital technology advances varies significantly. Digitalization in histopathology laboratory in Nigeria, is still a big setback, but there are digitalization in some of the usual routine practices like the automatic tissue processor which has overtaken the usual manual processor. In the area of sectioning, staining of tissues, mounting of slide and slide reading, we still face major setback in that regard. Digitalization in routine histopathology laboratory also offers new possibilities not available within the conventional microscope. A promising technique is automatic scoring and other kinds of digital image analysis (DIA). In a review, [1] conclude that current DIA methods are able to produce quantitative assessments of immunohistochemically stained slides with a similar variability as manual assessment. In other studies, quantitative digitalization methods have been shown to outperform manual work for certain applications, such as in Ki67 proliferation assessment [2] and prediction of recurrence in prostate cancer [3]. However, [3] highlight the fact that a full-scale investigation of DIA methods considering all aspects of the clinical situation is still lacking. In histopathology, and particularly in molecular pathology, there are an increasing number of tests, and an increasing demand to support faster, more-accurate disease diagnosis-and subsequent treatment and care-particularly for cancer (Figure 1).","PeriodicalId":15247,"journal":{"name":"Journal of Biosensors and Bioelectronics","volume":"138 1","pages":"1-4"},"PeriodicalIF":0.0,"publicationDate":"2017-12-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89215071","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}