Journal of Attention Disorders最新文献_第8页

Investigating Variations in Medicine Approvals for Attention-Deficit/Hyperactivity Disorder: A Cross-Country Document Analysis Comparing Drug Labeling. 调查注意力缺陷/多动症药物审批的差异：比较药物标签的跨国文件分析。

IF 2.7 3区医学

Journal of Attention Disorders Pub Date : 2024-09-01 Epub Date: 2024-02-07 DOI: 10.1177/10870547231224088

Laila Tanana, Asam Latif, Prasad S Nishtala, Timothy F Chen

{"title":"Investigating Variations in Medicine Approvals for Attention-Deficit/Hyperactivity Disorder: A Cross-Country Document Analysis Comparing Drug Labeling.","authors":"Laila Tanana, Asam Latif, Prasad S Nishtala, Timothy F Chen","doi":"10.1177/10870547231224088","DOIUrl":"10.1177/10870547231224088","url":null,"abstract":"Objective: This study aimed to compare the approval of medicines for attention deficit/hyperactivity disorder (ADHD) for pediatric patients across five countries.Method: A document analysis was completed, using the drug labeling for ADHD medicines from five countries; United Kingdom, Australia, New Zealand, Canada and United States (US). Comparisons of available formulations and approval information for ADHD medicine use in pediatric patients were made.Results: The US had the highest number of approved medicines and medicine forms across the studied countries (29 medicine forms for 10 approved medicines). Approved age and dosage variations across countries and missing dosage information were identified in several drug labeling.Conclusions: The discrepancies in approval information in ADHD medicine drug labeling and differing availability of medicine formulations across countries suggest variations in the management of ADHD across countries. The update of drug labeling and further research into reasons for variability and impact on practice are needed.","PeriodicalId":15237,"journal":{"name":"Journal of Attention Disorders","volume":" ","pages":"1437-1453"},"PeriodicalIF":2.7,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11328451/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139702648","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Genetic Association of Lipids and Lipid-Lowering Drug Target Genes With Attention Deficit Hyperactivity Disorder. 血脂和降脂药物靶基因与注意力缺陷多动障碍的遗传关系。

IF 2.7 3区医学

Journal of Attention Disorders Pub Date : 2024-09-01 Epub Date: 2024-01-03 DOI: 10.1177/10870547231222219

Detong Guo, Wenchao Sheng, Yingzi Cai, Jianbo Shu, Chunquan Cai

{"title":"Genetic Association of Lipids and Lipid-Lowering Drug Target Genes With Attention Deficit Hyperactivity Disorder.","authors":"Detong Guo, Wenchao Sheng, Yingzi Cai, Jianbo Shu, Chunquan Cai","doi":"10.1177/10870547231222219","DOIUrl":"10.1177/10870547231222219","url":null,"abstract":"Background: Lipid metabolism plays an essential role in nervous system development. Cholesterol deficiency leads to a variety of neurodevelopmental disorders, such as autism spectrum disorder and fragile X syndrome. There have been a lot of efforts to search for biological markers associated with and causal to ADHD, among which lipid is one possible etiological factor that is quite widely studied. We aimed to evaluate the causal relationship between lipids traits, lipid-lowering drugs, and attention deficit hyperactivity disorder (ADHD) outcomes using Mendelian randomization (MR) studies.Methods: We used summary data from genome-wide association studies to explore the causal relationships between circulating lipid-related traits and ADHD. Then, quantitative trait loci for the expression of lipid-lowering drug target genes and genetic variants associated with lipid traits were extracted. Summary-data-based MR and inverse-variance-weighted MR (IVW-MR) were used to investigate the correlation between the expression of these drug-target genes and ADHD.Results: After rigorous screening, 939 instrumental variables were finally included for univariable mendelian randomization analysis. However, there is no correlation between lipid profile and ADHD risk. Drug target analysis by IVW-MR method observed that APOB-mediated low-density lipoprotein cholesterol was associated with lower ADHD risk (odds ratio [OR] = 0.90, 95% confidence interval [CI] [0.84, 0.97]; p = .007), whereas LPL-mediated triglycerides levels were associated with a higher risk of ADHD (OR = 1.13, 95% CI [1.06, 1.21]; p < .001).Conclusion: Our results suggest that APOB gene and LPL gene may be candidate drug target genes for the treatment of ADHD.","PeriodicalId":15237,"journal":{"name":"Journal of Attention Disorders","volume":" ","pages":"1425-1436"},"PeriodicalIF":2.7,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139080584","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

EFL Special Education Teachers' Perspectives: Evaluating Game-Based Learning for ADHD Behavioral Disorders. EFL 特殊教育教师的观点：评估针对多动症行为障碍的游戏式学习。

IF 2.7 3区医学

Journal of Attention Disorders Pub Date : 2024-09-01 Epub Date: 2024-07-25 DOI: 10.1177/10870547241265877

Amr M Mohamed, Tahany S Shaaban, Hassen Alazhar Jmaiel

{"title":"EFL Special Education Teachers' Perspectives: Evaluating Game-Based Learning for ADHD Behavioral Disorders.","authors":"Amr M Mohamed, Tahany S Shaaban, Hassen Alazhar Jmaiel","doi":"10.1177/10870547241265877","DOIUrl":"10.1177/10870547241265877","url":null,"abstract":"Objective: The purpose of this study was to examine the perspectives of English as a Foreign Language Special Education teachers (EFLSE) regarding game-based learning approaches for addressing behavioral disorders in ADHD patients.Method: The study involved a sample (n = 131) of EFLSE teachers who completed a questionnaire to determine how feasible, acceptable, and helpful they found game-based learning.Results: The study revealed that EFLSE teachers perceive game-based learning to be a feasible and acceptable method for engaging ADHD students and helping to maintain their attention during game-based learning activities. Nevertheless, implementation and individualized approaches are cited as challenges. Additionally, EFLSE teachers emphasized the benefits of game-based learning, including improved problem-solving, assessment methods, collaboration, and the acquisition of academic skills.Conclusions: The study contributes insights for educators, policymakers, and researchers that can support the development of evidence-based interventions offering game-based learning for students with ADHD.","PeriodicalId":15237,"journal":{"name":"Journal of Attention Disorders","volume":" ","pages":"1482-1495"},"PeriodicalIF":2.7,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141758962","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Extended-Release Mixed Amphetamine Salts for Comorbid Adult Attention-Deficit/Hyperactivity Disorder and Cannabis Use Disorder: A Pilot, Randomized Double-Blind, Placebo-Controlled Trial. 缓释混合安非他明盐治疗成人注意力缺陷/多动障碍和大麻使用障碍：随机双盲安慰剂对照试验》。

IF 2.7 3区医学

Journal of Attention Disorders Pub Date : 2024-09-01 Epub Date: 2024-07-25 DOI: 10.1177/10870547241264675

Frances R Levin, John J Mariani, Martina Pavlicova, C Jean Choi, Cale Basaraba, Amy L Mahony, Daniel J Brooks, Christina A Brezing, Nasir Naqvi

{"title":"Extended-Release Mixed Amphetamine Salts for Comorbid Adult Attention-Deficit/Hyperactivity Disorder and Cannabis Use Disorder: A Pilot, Randomized Double-Blind, Placebo-Controlled Trial.","authors":"Frances R Levin, John J Mariani, Martina Pavlicova, C Jean Choi, Cale Basaraba, Amy L Mahony, Daniel J Brooks, Christina A Brezing, Nasir Naqvi","doi":"10.1177/10870547241264675","DOIUrl":"10.1177/10870547241264675","url":null,"abstract":"Objective: To determine if treatment of co-occurring adult ADHD and Cannabis Use Disorder (CUD) with extended-release mixed amphetamine salts (MAS-ER) would be effective at improving ADHD symptoms and promoting abstinence.Method: A 12-week randomized, double-blind, two-arm pilot feasibility trial of adults with comorbid ADHD and CUD (n = 28) comparing MAS-ER (80 mg) to placebo. Main outcomes: ADHD: ≥30% symptom reduction, measured by the Adult ADHD Investigator Symptom Rating Scale (AISRS). CUD: Abstinence during last 2 observed weeks of maintenance phase.Results: Overall, medication was well-tolerated. There was no significant difference in ADHD symptom reduction (MAS-ER: 83.3%; placebo: 71.4%; p = .65) or cannabis abstinence (MAS-ER: 15.4%; placebo: 0%; p = .27). MAS-ER group showed a significant decrease in weekly cannabis use days over time compared to placebo (p < .0001).Conclusions: MAS-ER was generally well-tolerated. The small sample size precluded a determination of MAS-ER's superiority reducing ADHD symptoms or promoting abstinence. Notably, MAS-ER significantly reduced weekly days of use over time.","PeriodicalId":15237,"journal":{"name":"Journal of Attention Disorders","volume":" ","pages":"1467-1481"},"PeriodicalIF":2.7,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141758963","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Continuation of Treatment in Children With ADHD: A Multicenter Turkish Sample Study. 多动症儿童的持续治疗：土耳其多中心样本研究

IF 2.7 3区医学

Journal of Attention Disorders Pub Date : 2024-09-01 Epub Date: 2024-01-31 DOI: 10.1177/10870547231222021

Saliha Baykal, Cansu Çobanoğlu Osmanlı, Abdullah Bozkurt, Bedia Sultan Önal, Berkan Şahin, Müge Karaçizmeli, Ayşegül Öz Gazi, Koray Karabekiroğlu

{"title":"Continuation of Treatment in Children With ADHD: A Multicenter Turkish Sample Study.","authors":"Saliha Baykal, Cansu Çobanoğlu Osmanlı, Abdullah Bozkurt, Bedia Sultan Önal, Berkan Şahin, Müge Karaçizmeli, Ayşegül Öz Gazi, Koray Karabekiroğlu","doi":"10.1177/10870547231222021","DOIUrl":"10.1177/10870547231222021","url":null,"abstract":"Objectives: The aim of this study was to investigate the variables that may affect treatment continuation in children aged 6 to 12 years who were newly diagnosed with ADHD.Methods: A total of 132 children diagnosed with ADHD and their parents participated in the study. Sociodemographic and clinical risk factors affecting continuation of treatment were examined using logistic regression analysis.Results: Multiple model examination revealed that greater age increased the risk of treatment discontinuation 1.824 times (p = .003) while a lower total length of paternal education increased the risk of discontinuation (1/0.835) 1.198 times (p = .022). Other variables emerging as significant in the univariate model lost that significance in the multiple model.Conclusions: Understanding the variables associated with medication discontinuation in ADHD in different populations and taking these variables into account in the development of health policies, will be useful in improving the long-term devastating effects of the disorder.","PeriodicalId":15237,"journal":{"name":"Journal of Attention Disorders","volume":" ","pages":"1415-1424"},"PeriodicalIF":2.7,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139642215","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Associations of Symptoms of ADHD and Oppositional Defiant Disorder (ODD) in Adolescence With Occupational Outcomes and Incomes in Adulthood. 青春期多动症和对抗性违抗障碍 (ODD) 症状与成年后职业结果和收入的关系。

IF 2.7 3区医学

Journal of Attention Disorders Pub Date : 2024-08-01 Epub Date: 2024-06-12 DOI: 10.1177/10870547241259329

Sampo Seppä, Sanna Huikari, Marko Korhonen, Tanja Nordström, Tuula Hurtig, Anu-Helmi Halt

{"title":"Associations of Symptoms of ADHD and Oppositional Defiant Disorder (ODD) in Adolescence With Occupational Outcomes and Incomes in Adulthood.","authors":"Sampo Seppä, Sanna Huikari, Marko Korhonen, Tanja Nordström, Tuula Hurtig, Anu-Helmi Halt","doi":"10.1177/10870547241259329","DOIUrl":"10.1177/10870547241259329","url":null,"abstract":"Objective: The purpose of this study was to examine the associations of ADHD and ODD symptoms in adolescence with occupational outcomes and incomes in adulthood within the Northern Finland Birth Cohort 1986 (NFBC1986).Method: ADHD symptoms were evaluated at ages 15 to 16 years using the Strengths and Weaknesses of ADHD symptoms and Normal Behaviors (SWAN) scale. ODD symptoms were assessed using a 7-point scale, like the SWAN assessment.Results: Symptoms of ADHD and ADHD + ODD were associated with elevated rates of unemployment, increased sick days, and lower annual incomes compared to controls for both sexes. Symptoms of ODD were associated with higher unemployment and more sick days for males, although these associations did not reach statistical significance in their association with annual incomes.Conclusion: Symptoms of ADHD were associated with adverse occupational outcomes and lower incomes. Furthermore, symptoms of ODD were associated with occupational outcomes but not with incomes.","PeriodicalId":15237,"journal":{"name":"Journal of Attention Disorders","volume":" ","pages":"1392-1405"},"PeriodicalIF":2.7,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11292981/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141310763","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Associations Between ADHD Symptomatology, Motivation for Physical Activity, and Technology Acceptability in Young Adult Women With Obesity. 肥胖症年轻成年女性的多动症症状、体育锻炼动机和技术可接受性之间的关系。

IF 2.7 3区医学

Journal of Attention Disorders Pub Date : 2024-08-01 Epub Date: 2024-05-14 DOI: 10.1177/10870547241253157

Meggy Hayotte, Prescilia Roubaud, Barbara Bersia, Véronique Nègre, Fabienne d'Arripe-Longueville

{"title":"Associations Between ADHD Symptomatology, Motivation for Physical Activity, and Technology Acceptability in Young Adult Women With Obesity.","authors":"Meggy Hayotte, Prescilia Roubaud, Barbara Bersia, Véronique Nègre, Fabienne d'Arripe-Longueville","doi":"10.1177/10870547241253157","DOIUrl":"10.1177/10870547241253157","url":null,"abstract":"Objective: This study examined the relationships between ADHD symptomatology, the motivations for physical activity (PA) according to self-determination theory, and the acceptability of three PA promotion technologies (active video game, mobile application, and telehealth) according to the dimensions of the unified theory of acceptance and use of technology-2 (UTAUT2).Method: A total of 312 women, aged 30.7 ± 7.1 years, followed for obesity with an average body mass index of 34.5 ± 7.8 kg/m², were included in this sub-analysis.Results: Fifty-seven individuals (18.3%) were identified with positive screening symptoms of ADHD. No differences emerged regarding acceptability of technology-based PA. However, individuals with positive screening for ADHD tended to have higher scores for acceptability of active video game on the UTAUT2 dimensions of effort expectancy and hedonic motivation.Conclusion: This study suggests that active video game may be more appropriate than other technologies for individuals with obesity and ADHD symptoms.","PeriodicalId":15237,"journal":{"name":"Journal of Attention Disorders","volume":" ","pages":"1406-1411"},"PeriodicalIF":2.7,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140922362","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Sex Differences in Diagnosis and Treatment Timing of Comorbid Depression/Anxiety and Disease Subtypes in Patients With ADHD: A Database Study. 多动症患者合并抑郁/焦虑和疾病亚型的诊断和治疗时机的性别差异：一项数据库研究。

IF 2.7 3区医学

Journal of Attention Disorders Pub Date : 2024-08-01 Epub Date: 2024-05-16 DOI: 10.1177/10870547241251738

Uzma Siddiqui, Mitchell M Conover, Erica A Voss, David M Kern, Michelle Litvak, José Antunes

引用次数: 0

Interactive Effects of Racism and Racial Centrality on ADHD Symptoms. 种族主义和种族中心性对多动症症状的交互影响。

IF 2.7 3区医学

Journal of Attention Disorders Pub Date : 2024-08-01 Epub Date: 2024-05-28 DOI: 10.1177/10870547241256453

Kaylee Boyd, Maryam Ware, Yara Mekawi

引用次数: 0

A Network Approach to Understanding the Role of Executive Functioning and Alpha Oscillations in Inattention and Hyperactivity-Impulsivity Symptoms of ADHD. 通过网络方法了解执行功能和阿尔法振荡在注意力不集中和多动症的过度活跃-冲动症状中的作用。

IF 2.7 3区医学

Journal of Attention Disorders Pub Date : 2024-08-01 Epub Date: 2024-05-26 DOI: 10.1177/10870547241253999

Juan Diego Vera, René Freichel, Giorgia Michelini, Sandra K Loo, Agatha Lenartowicz

{"title":"A Network Approach to Understanding the Role of Executive Functioning and Alpha Oscillations in Inattention and Hyperactivity-Impulsivity Symptoms of ADHD.","authors":"Juan Diego Vera, René Freichel, Giorgia Michelini, Sandra K Loo, Agatha Lenartowicz","doi":"10.1177/10870547241253999","DOIUrl":"10.1177/10870547241253999","url":null,"abstract":"Objective: ADHD is a prevalent neurodevelopmental disorder characterized by symptoms of inattention and hyperactivity-impulsivity. Impairments in executive functioning (EF) are central to models of ADHD, while alpha-band spectral power event-related decreases (ERD) have emerged as a putative electroencephalography (EEG) biomarker of EF in ADHD. Little is known about the roles of EF and alpha ERD and their interactions with symptoms of ADHD.Method: We estimated network models of ADHD symptoms and integrated alpha ERD measures into the symptom network.Results: EF emerges as a bridge network node connecting alpha ERD and the hyperactivity/impulsivity and inattention symptoms. We found that EF most closely relates to a subset of symptoms, namely the motoric symptoms, \"seat\" (difficulty staying seated), and \"runs\" (running or climbing excessively).Conclusions: EF functions as a bridge node connecting alpha ERD and the ADHD symptom network. Motoric-type symptoms and EF deficits may constitute important nodes in the interplay between behavior/symptoms, cognition, and neurophysiological markers of ADHD.","PeriodicalId":15237,"journal":{"name":"Journal of Attention Disorders","volume":" ","pages":"1357-1367"},"PeriodicalIF":2.7,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11292971/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141155215","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0