{"title":"Emerging Indicators of Left Atrial Function Evaluation Considering the Unique Characteristics of Hypertrophic Cardiomyopathy.","authors":"Hyemoon Chung","doi":"10.4250/jcvi.2022.0116","DOIUrl":"https://doi.org/10.4250/jcvi.2022.0116","url":null,"abstract":"► See","PeriodicalId":15229,"journal":{"name":"Journal of Cardiovascular Imaging","volume":"31 1","pages":"49-50"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/99/cf/jcvi-31-49.PMC9880344.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10668361","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Se-Jung Yoon, Sungha Park, Eui-Young Choi, Hye-Sun Seo, Chi Young Shim, Chul Min Ahn, Sung-Ai Kim, Jong-Won Ha
{"title":"Left Atrial Velocity Vector Imaging Can Assess Early Diastolic Dysfunction in Left Ventricular Hypertrophy and Hypertrophic Cardiomyopathy.","authors":"Se-Jung Yoon, Sungha Park, Eui-Young Choi, Hye-Sun Seo, Chi Young Shim, Chul Min Ahn, Sung-Ai Kim, Jong-Won Ha","doi":"10.4250/jcvi.2022.0064","DOIUrl":"https://doi.org/10.4250/jcvi.2022.0064","url":null,"abstract":"<p><strong>Background: </strong>The function of left atrium (LA) is difficult to assess because of its ventricle-dependent, dynamic movement. The aim of this study was to assess LA function using velocity vector imaging (VVI) and compare LA function in patients with hypertrophic cardiomyopathy (HCMP) and left ventricular hypertrophy (LVH) with normal controls.</p><p><strong>Methods: </strong>Fourteen patients with HCMP (72% male, mean age of 52.6 ± 9.8), 15 hypertensive patients with LVH (88% male, mean age of 54.0 ± 15.3), and 10 age-matched controls (83% male, mean age of 50.0 ± 4.6) were prospectively studied. Echocardiographic images of the LA were analyzed with VVI, and strain rate (SR) was compared among the 3 groups.</p><p><strong>Results: </strong>The e' velocity (7.7 ± 1.1; 5.1 ± 0.8; 4.5 ± 1.3 cm/sec, p = 0.013), E/e' (6.8 ± 1.6; 12.4 ± 3.3; 14.7 ± 4.2, p = 0.035), and late diastolic SR at mid LA (-1.65 ± 0.51; -0.97 ± 0.55; -0.82 ± 0.32, p = 0.002) were significantly different among the groups (normal; LVH; HCMP, respectively). The e' velocity, E/e', and late diastolic SR at mid LA were significantly different between normal and LVH (p = 0.001; 0.022; 0.018), whereas LA size was similar between normal and LVH (p = 0.592). The mean late diastolic peak SR of mid LA was significantly correlated with indices of diastolic function (E/e', e', and LA size).</p><p><strong>Conclusions: </strong>The SR is a useful tool for detailed evaluation of LA function, especially early dysfunction of LA in groups with normal LA size.</p>","PeriodicalId":15229,"journal":{"name":"Journal of Cardiovascular Imaging","volume":"31 1","pages":"41-48"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/0c/44/jcvi-31-41.PMC9880349.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10668360","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Assessment Regarding the Safety of Stress Cardiovascular Magnetic Resonance in Patients With Moderate to Severe Aortic Stenosis.","authors":"Sung-Ji Park","doi":"10.4250/jcvi.2022.0109","DOIUrl":"https://doi.org/10.4250/jcvi.2022.0109","url":null,"abstract":"AS is often associated with coronary artery disease (CAD) and the most common form of valvular heart disease in elderly patients. Significant CAD was found in 10.6% of patients with severe AS in our previous study.2) Evaluation of the functional significance of CAD in patients with severe AS is clinically relevant for planning a potential percutaneous coronary intervention or coronary artery bypass grafting (CABG). However, evidence regarding the role of stress testing in severe AS is lacking. Guidelines recommending testing may uncover symptoms and is recommended for risk stratification of asymptomatic patients with severe AS. Exercise echocardiography provides additional prognostic information based on assessment of the increase in mean pressure gradient and change in left ventricular (LV) function.3)","PeriodicalId":15229,"journal":{"name":"Journal of Cardiovascular Imaging","volume":"31 1","pages":"39-40"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/1e/02/jcvi-31-39.PMC9880351.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10659624","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Janek Salatzki, Andreas Ochs, Nadja Kirchgäßner, Jannick Heins, Sebastian Seitz, Hauke Hund, Derliz Mereles, Matthias G Friedrich, Hugo A Katus, Norbert Frey, Florian André, Marco M Ochs
{"title":"Safety of Stress Cardiac Magnetic Resonance in Patients With Moderate to Severe Aortic Valve Stenosis.","authors":"Janek Salatzki, Andreas Ochs, Nadja Kirchgäßner, Jannick Heins, Sebastian Seitz, Hauke Hund, Derliz Mereles, Matthias G Friedrich, Hugo A Katus, Norbert Frey, Florian André, Marco M Ochs","doi":"10.4250/jcvi.2022.0063","DOIUrl":"https://doi.org/10.4250/jcvi.2022.0063","url":null,"abstract":"<p><strong>Background: </strong>Dobutamine and adenosine stress cardiac magnetic resonance (CMR) imaging is relatively contraindicated in patients with moderate to severe aortic valve stenosis (AS). We aimed to determine the safety of dobutamine and adenosine stress CMR in patients with moderate to severe AS.</p><p><strong>Methods: </strong>In this retrospective study patients with AS who underwent either dobutamine or adenosine stress CMR for exclusion of obstructive coronary artery disease were enrolled. We recorded clinical data, CMR and echocardiography findings, and complications as well as minor symptoms. Patients with AS were compared to matched individuals without AS.</p><p><strong>Results: </strong>A total of 187 patients with AS were identified and compared to age-, gender- and body mass index-matched 187 patients without AS. No severe complications were reported in the study nor the control group. The reported frequency of non-severe complications and minor symptoms were similar between the study and the control groups. Nineteen patients with AS experienced non-severe complications or minor symptoms during dobutamine stress CMR compared to eighteen patients without AS (p = 0.855). One patient with AS and two patients without AS undergoing adenosine stress CMR experienced minor symptoms (p = 0.562). Four examinations were aborted because of chest pain, paroxysmal atrial fibrillation and third-degree atrioventricular block. Inducible ischaemia, prior coronary artery bypass grafting, prior stroke and age were associated with a higher incidence of complications and minor symptoms.</p><p><strong>Conclusions: </strong>Moderate to severe AS was not associated with complications during CMR stress test. The incidence of non-severe complications and minor symptoms was greater with dobutamine.</p>","PeriodicalId":15229,"journal":{"name":"Journal of Cardiovascular Imaging","volume":"31 1","pages":"26-38"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/99/e1/jcvi-31-26.PMC9880345.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10667990","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Right Ventricular Performance in Uncontrolled Hypertensive Patients: 2D vs. 4D Echo Study.","authors":"Sang Jin Ha","doi":"10.4250/jcvi.2022.0070","DOIUrl":"10.4250/jcvi.2022.0070","url":null,"abstract":"","PeriodicalId":15229,"journal":{"name":"Journal of Cardiovascular Imaging","volume":"30 4","pages":"290-291"},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/ee/05/jcvi-30-290.PMC9592246.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40585695","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Do We Really Need to Predict Paravalvular Regurgitation After TAVI With Aortic Valve Calcium Load Before the Procedure?","authors":"Woo-Baek Chung","doi":"10.4250/jcvi.2022.0075","DOIUrl":"10.4250/jcvi.2022.0075","url":null,"abstract":"","PeriodicalId":15229,"journal":{"name":"Journal of Cardiovascular Imaging","volume":"30 4","pages":"305-306"},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/16/80/jcvi-30-305.PMC9592248.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40585696","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nahid El Faquir, Quinten Wolff, Rafi Sakhi, Ben Ren, Zouhair Rahhab, Sander van Weenen, Patrick Geeve, Ricardo P J Budde, Eric Boersma, Joost Daemen, Nicolas M van Mieghem, Peter P de Jaegere
{"title":"Distribution of Aortic Root Calcium in Relation to Frame Expansion and Paravalvular Leakage After Transcatheter Aortic Valve Implantation (TAVI): An Observational Study Using a Patient-specific Contrast Attenuation Coefficient for Calcium Definition and Independent Core Lab Analysis of Paravalvular Leakage.","authors":"Nahid El Faquir, Quinten Wolff, Rafi Sakhi, Ben Ren, Zouhair Rahhab, Sander van Weenen, Patrick Geeve, Ricardo P J Budde, Eric Boersma, Joost Daemen, Nicolas M van Mieghem, Peter P de Jaegere","doi":"10.4250/jcvi.2021.0141","DOIUrl":"https://doi.org/10.4250/jcvi.2021.0141","url":null,"abstract":"<p><strong>Background: </strong>Calcium is a determinant of paravalvular leakage (PVL) after transcatheter aortic valve implantation (TAVI). This is based on a fixed contrast attenuation value while X-ray attenuation is patient-dependent and without considering frame expansion and PVL location. We examined the role of calcium in (site-specific) PVL after TAVI using a patient-specific contrast attenuation coefficient combined with frame expansion.</p><p><strong>Methods: </strong>57 patients were included with baseline CT, post-TAVI transthoracic echocardiography and rotational angiography (R-angio). Calcium load was assessed using a patient-specific contrast attenuation coefficient. Baseline CT and post-TAVI R-angio were fused to assess frame expansion. PVL was assessed by a core lab.</p><p><strong>Results: </strong>Overall, the highest calcium load was at the non-coronary-cusp-region (NCR, 436 mm<sup>3</sup>) vs. the right-coronary-cusp-region (RCR, 233 mm<sup>3</sup>) and the left-coronary-cusp-region (LCR, 244 mm<sup>3</sup>), p < 0.001. Calcium load was higher in patients with vs. without PVL (1,137 vs. 742 mm<sup>3</sup>, p = 0.012) and was an independent predictor of PVL (odds ratio, 4.83, p = 0.004). PVL was seen most often in the LCR (39% vs. 21% [RCR] and 19% [NCR]). The degree of frame expansion was 71% at the NCR, 70% at the RCR and 74% at the LCR without difference between patients with or without PVL.</p><p><strong>Conclusions: </strong>Calcium load was higher in patients with PVL and was an independent predictor of PVL. While calcium was predominantly seen at the NCR, PVL was most often at the LCR. These findings indicate that in addition to calcium, specific anatomic features play a role in PVL after TAVI.</p>","PeriodicalId":15229,"journal":{"name":"Journal of Cardiovascular Imaging","volume":"30 4","pages":"292-304"},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/e7/31/jcvi-30-292.PMC9592252.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40585697","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Evaluation of Cardiac Mechanical Dyssynchrony in Heart Failure Patients Using Current Echo-Doppler Modalities.","authors":"Rehab M Hamdy, Hend Osama, Hanaa M Fereig","doi":"10.4250/jcvi.2022.0061","DOIUrl":"10.4250/jcvi.2022.0061","url":null,"abstract":"<p><strong>Background: </strong>Current guidelines indicate electrical dyssynchrony as the major criteria for selecting patients for cardiac resynchronization therapy, and 25-35% of patients exhibit unfavorable responses to cardiac resynchronization therapy (CRT). We aimed to evaluate different cardiac mechanical dyssynchrony parameters in heart failure patients using current echo-Doppler modalities and we analyzed their association with electrical dyssynchrony.</p><p><strong>Methods: </strong>The study included 120 heart failure with reduced ejection fraction (HFrEF) who underwent assessments for left ventricular mechanical dyssynchrony (LVMD) and interventricular mechanical dyssynchrony (IVMD).</p><p><strong>Results: </strong>Patients were classified according to QRS duration: group I with QRS < 120 ms, group II with QRS 120-149 ms, and group III with QRS ≥ 150 ms. Group III had significantly higher IVMD, LVMD indices, TS-SD speckle-tracking echocardiography (STE) 12 segments (standard deviation of time to peak longitudinal strain speckle tracking echocardiography in 12 LV-segments), and LVMD score compared with group I and group II. Group II and group III were classified according to QRS morphology into left bundle branch block (LBBB) and non-LBBB subgroups. LVMD score, TS-SD 12 TDI, and TS-SD 12 STE had good correlations with QRS duration.</p><p><strong>Conclusions: </strong>HFrEF patients with wide QRS duration (> 150 ms) had more evident LVMD compared with patients with narrow or intermediate QRS. Those patients with intermediate QRS duration (120-150 ms) had substantial LVMD assessed by both TDI and 2D STE, regardless of QRS morphology. Subsequently, we suggest that LVMD indices might be employed as additive criteria to predict CRT response in that patient subgroup. Electrical and mechanical dyssynchrony were strongly correlated in HFrEF patients.</p>","PeriodicalId":15229,"journal":{"name":"Journal of Cardiovascular Imaging","volume":"30 4","pages":"307-319"},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/72/04/jcvi-30-307.PMC9592249.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40585699","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Muhannad A Abbasi, Allison M Blake, Roberto Sarnari, Daniel Lee, Allen S Anderson, Kambiz Ghafourian, Sadiya S Khan, Esther E Vorovich, Jonathan D Rich, Jane E Wilcox, Clyde W Yancy, James C Carr, Michael Markl
{"title":"Multiparametric Cardiac Magnetic Resonance Imaging Detects Altered Myocardial Tissue and Function in Heart Transplantation Recipients Monitored for Cardiac Allograft Vasculopathy.","authors":"Muhannad A Abbasi, Allison M Blake, Roberto Sarnari, Daniel Lee, Allen S Anderson, Kambiz Ghafourian, Sadiya S Khan, Esther E Vorovich, Jonathan D Rich, Jane E Wilcox, Clyde W Yancy, James C Carr, Michael Markl","doi":"10.4250/jcvi.2022.0003","DOIUrl":"https://doi.org/10.4250/jcvi.2022.0003","url":null,"abstract":"<p><strong>Background: </strong>Cardiac allograft vasculopathy (CAV) is a complication beyond the first-year post-heart transplantation (HTx). We aimed to test the utility of cardiac magnetic resonance (CMR) to detect functional/structural changes in HTx recipients with CAV.</p><p><strong>Methods: </strong>Seventy-seven prospectively recruited HTx recipients beyond the first-year post-HTx and 18 healthy controls underwent CMR, including cine imaging of ventricular function and T1- and T2-mapping to assess myocardial tissue changes. Data analysis included quantification of global cardiac function and regional T2, T1 and extracellular volume based on the 16-segment model. International Society for Heart and Lung Transplantation criteria was used to adjudicate CAV grade (0-3) based on coronary angiography.</p><p><strong>Results: </strong>The majority of HTx recipients (73%) presented with CAV (1: n = 42, 2/3: n = 14, 0: n = 21). Global and segmental T2 (49.5 ± 3.4 ms vs 50.6 ± 3.4 ms, p < 0.001;16/16 segments) were significantly elevated in CAV-0 compared to controls. When comparing CAV-2/3 to CAV-1, global and segmental T2 were significantly increased (53.6 ± 3.2 ms vs. 50.6 ± 2.9 ms, p < 0.001; 16/16 segments) and left ventricular ejection fraction was significantly decreased (54 ± 9% vs. 59 ± 9%, p < 0.05). No global, structural, or functional differences were seen between CAV-0 and CAV-1.</p><p><strong>Conclusions: </strong>Transplanted hearts display functional and structural alteration compared to native hearts, even in those without evidence of macrovasculopathy (CAV-0). In addition, CMR tissue parameters were sensitive to changes in CAV-1 vs. 2/3 (mild vs. moderate/severe). Further studies are warranted to evaluate the diagnostic value of CMR for the detection and classification of CAV.</p>","PeriodicalId":15229,"journal":{"name":"Journal of Cardiovascular Imaging","volume":"30 4","pages":"263-275"},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/6c/51/jcvi-30-263.PMC9592247.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40585693","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Correlation Between Electrical and Mechanical Dyssynchrony in Patients With Heart Failure With Reduced Ejection Fraction.","authors":"Hyun-Jin Kim","doi":"10.4250/jcvi.2022.0095","DOIUrl":"10.4250/jcvi.2022.0095","url":null,"abstract":"","PeriodicalId":15229,"journal":{"name":"Journal of Cardiovascular Imaging","volume":"30 4","pages":"320-321"},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/68/e0/jcvi-30-320.PMC9592254.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40585698","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}