Journal of Cardiovascular Imaging最新文献

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Utility of Multidetector Computed Tomographic Angiography as an Alternative to Transesophageal Echocardiogram for Preoperative Transcatheter Mitral Valve Repair Planning. 多探测器计算机断层血管造影作为经食管超声心动图的替代方案在经导管二尖瓣术前修复计划中的应用。
Journal of Cardiovascular Imaging Pub Date : 2023-01-01 DOI: 10.4250/jcvi.2022.0043
Craig Basman, Caroline Ong, Tikal Kansara, Zain Kassam, Caleb Wutawunashe, Jennifer Conroy, Arber Kodra, Biana Trost, Priti Mehla, Luigi Pirelli, Jacob Scheinerman, Varinder P Singh, Chad A Kliger
{"title":"Utility of Multidetector Computed Tomographic Angiography as an Alternative to Transesophageal Echocardiogram for Preoperative Transcatheter Mitral Valve Repair Planning.","authors":"Craig Basman,&nbsp;Caroline Ong,&nbsp;Tikal Kansara,&nbsp;Zain Kassam,&nbsp;Caleb Wutawunashe,&nbsp;Jennifer Conroy,&nbsp;Arber Kodra,&nbsp;Biana Trost,&nbsp;Priti Mehla,&nbsp;Luigi Pirelli,&nbsp;Jacob Scheinerman,&nbsp;Varinder P Singh,&nbsp;Chad A Kliger","doi":"10.4250/jcvi.2022.0043","DOIUrl":"https://doi.org/10.4250/jcvi.2022.0043","url":null,"abstract":"<p><strong>Background: </strong>Three-dimensional (3D) transesophageal echocardiogram (TEE) is the gold standard for the diagnosis of degenerative mitral regurgitation (dMR) and preoperative planning for transcatheter mitral valve repair (TMVr). TEE is an invasive modality requiring anesthesia and esophageal intubation. The severe acute respiratory syndrome coronavirus 2 pandemic has limited the number of elective invasive procedures. Multi-detector computed tomographic angiography (MDCT) provides high-resolution images and 3D reconstructions to assess complex mitral anatomy. We hypothesized that MDCT would reveal similar information to TEE relevant to TMVr, thus deferring the need for a preoperative TEE in certain situations like during a pandemic.</p><p><strong>Methods: </strong>We retrospectively analyzed data on patients who underwent or were evaluated for TMVr for dMR with preoperative MDCT and TEE between 2017 and 2019. Two TEE and 2 MDCT readers, blinded to patient outcome, analyzed: leaflet pathology (flail, degenerative, mixed), leaflet location, mitral valve area (MVA), flail width/gap, anterior-posterior (AP) and commissural diameters, posterior leaflet length, leaflet thickness, presence of mitral valve cleft and degree of mitral annular calcification (MAC).</p><p><strong>Results: </strong>A total of 22 (out of 87) patients had preoperative MDCT. MDCT correctly identified the leaflet pathology in 77% (17/22), flail leaflet in 91% (10/11), MAC degree in 91% (10/11) and the dysfunctional leaflet location in 95% (21/22) of patients. There were no differences in the measurements for MVA, flail width, commissural or AP diameter, posterior leaflet length, and leaflet thickness. MDCT overestimated the measurements of flail gap.</p><p><strong>Conclusions: </strong>For preoperative TMVr planning, MDCT provided similar measurements to TEE in our study.</p>","PeriodicalId":15229,"journal":{"name":"Journal of Cardiovascular Imaging","volume":"31 1","pages":"18-23"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/d3/33/jcvi-31-18.PMC9880348.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10667988","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Emerging Indicators of Left Atrial Function Evaluation Considering the Unique Characteristics of Hypertrophic Cardiomyopathy. 考虑肥厚性心肌病独特特征的左心功能评价新指标。
Journal of Cardiovascular Imaging Pub Date : 2023-01-01 DOI: 10.4250/jcvi.2022.0116
Hyemoon Chung
{"title":"Emerging Indicators of Left Atrial Function Evaluation Considering the Unique Characteristics of Hypertrophic Cardiomyopathy.","authors":"Hyemoon Chung","doi":"10.4250/jcvi.2022.0116","DOIUrl":"https://doi.org/10.4250/jcvi.2022.0116","url":null,"abstract":"► See","PeriodicalId":15229,"journal":{"name":"Journal of Cardiovascular Imaging","volume":"31 1","pages":"49-50"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/99/cf/jcvi-31-49.PMC9880344.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10668361","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Can Multidetector Computed Tomographic Angiography Replace Transesophageal Echocardiography for Preoperative Transcatheter Edge-to-Edge Mitral Valve Repair Planning Purposes? 多检测器计算机断层血管造影能否取代经食管超声心动图用于术前经导管二尖瓣边缘到边缘修复计划?
Journal of Cardiovascular Imaging Pub Date : 2023-01-01 DOI: 10.4250/jcvi.2022.0107
Sung-Ji Park
{"title":"Can Multidetector Computed Tomographic Angiography Replace Transesophageal Echocardiography for Preoperative Transcatheter Edge-to-Edge Mitral Valve Repair Planning Purposes?","authors":"Sung-Ji Park","doi":"10.4250/jcvi.2022.0107","DOIUrl":"https://doi.org/10.4250/jcvi.2022.0107","url":null,"abstract":"an Alternative","PeriodicalId":15229,"journal":{"name":"Journal of Cardiovascular Imaging","volume":"31 1","pages":"24-25"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/5e/10/jcvi-31-24.PMC9880352.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10667989","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Left Atrial Velocity Vector Imaging Can Assess Early Diastolic Dysfunction in Left Ventricular Hypertrophy and Hypertrophic Cardiomyopathy. 左房速度矢量成像评价左室肥厚和肥厚型心肌病早期舒张功能障碍。
Journal of Cardiovascular Imaging Pub Date : 2023-01-01 DOI: 10.4250/jcvi.2022.0064
Se-Jung Yoon, Sungha Park, Eui-Young Choi, Hye-Sun Seo, Chi Young Shim, Chul Min Ahn, Sung-Ai Kim, Jong-Won Ha
{"title":"Left Atrial Velocity Vector Imaging Can Assess Early Diastolic Dysfunction in Left Ventricular Hypertrophy and Hypertrophic Cardiomyopathy.","authors":"Se-Jung Yoon,&nbsp;Sungha Park,&nbsp;Eui-Young Choi,&nbsp;Hye-Sun Seo,&nbsp;Chi Young Shim,&nbsp;Chul Min Ahn,&nbsp;Sung-Ai Kim,&nbsp;Jong-Won Ha","doi":"10.4250/jcvi.2022.0064","DOIUrl":"https://doi.org/10.4250/jcvi.2022.0064","url":null,"abstract":"<p><strong>Background: </strong>The function of left atrium (LA) is difficult to assess because of its ventricle-dependent, dynamic movement. The aim of this study was to assess LA function using velocity vector imaging (VVI) and compare LA function in patients with hypertrophic cardiomyopathy (HCMP) and left ventricular hypertrophy (LVH) with normal controls.</p><p><strong>Methods: </strong>Fourteen patients with HCMP (72% male, mean age of 52.6 ± 9.8), 15 hypertensive patients with LVH (88% male, mean age of 54.0 ± 15.3), and 10 age-matched controls (83% male, mean age of 50.0 ± 4.6) were prospectively studied. Echocardiographic images of the LA were analyzed with VVI, and strain rate (SR) was compared among the 3 groups.</p><p><strong>Results: </strong>The e' velocity (7.7 ± 1.1; 5.1 ± 0.8; 4.5 ± 1.3 cm/sec, p = 0.013), E/e' (6.8 ± 1.6; 12.4 ± 3.3; 14.7 ± 4.2, p = 0.035), and late diastolic SR at mid LA (-1.65 ± 0.51; -0.97 ± 0.55; -0.82 ± 0.32, p = 0.002) were significantly different among the groups (normal; LVH; HCMP, respectively). The e' velocity, E/e', and late diastolic SR at mid LA were significantly different between normal and LVH (p = 0.001; 0.022; 0.018), whereas LA size was similar between normal and LVH (p = 0.592). The mean late diastolic peak SR of mid LA was significantly correlated with indices of diastolic function (E/e', e', and LA size).</p><p><strong>Conclusions: </strong>The SR is a useful tool for detailed evaluation of LA function, especially early dysfunction of LA in groups with normal LA size.</p>","PeriodicalId":15229,"journal":{"name":"Journal of Cardiovascular Imaging","volume":"31 1","pages":"41-48"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/0c/44/jcvi-31-41.PMC9880349.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10668360","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Assessment Regarding the Safety of Stress Cardiovascular Magnetic Resonance in Patients With Moderate to Severe Aortic Stenosis. 中重度主动脉瓣狭窄患者应激性心血管磁共振的安全性评价
Journal of Cardiovascular Imaging Pub Date : 2023-01-01 DOI: 10.4250/jcvi.2022.0109
Sung-Ji Park
{"title":"Assessment Regarding the Safety of Stress Cardiovascular Magnetic Resonance in Patients With Moderate to Severe Aortic Stenosis.","authors":"Sung-Ji Park","doi":"10.4250/jcvi.2022.0109","DOIUrl":"https://doi.org/10.4250/jcvi.2022.0109","url":null,"abstract":"AS is often associated with coronary artery disease (CAD) and the most common form of valvular heart disease in elderly patients. Significant CAD was found in 10.6% of patients with severe AS in our previous study.2) Evaluation of the functional significance of CAD in patients with severe AS is clinically relevant for planning a potential percutaneous coronary intervention or coronary artery bypass grafting (CABG). However, evidence regarding the role of stress testing in severe AS is lacking. Guidelines recommending testing may uncover symptoms and is recommended for risk stratification of asymptomatic patients with severe AS. Exercise echocardiography provides additional prognostic information based on assessment of the increase in mean pressure gradient and change in left ventricular (LV) function.3)","PeriodicalId":15229,"journal":{"name":"Journal of Cardiovascular Imaging","volume":"31 1","pages":"39-40"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/1e/02/jcvi-31-39.PMC9880351.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10659624","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Safety of Stress Cardiac Magnetic Resonance in Patients With Moderate to Severe Aortic Valve Stenosis. 应激性心脏磁共振在中重度主动脉瓣狭窄患者中的安全性。
Journal of Cardiovascular Imaging Pub Date : 2023-01-01 DOI: 10.4250/jcvi.2022.0063
Janek Salatzki, Andreas Ochs, Nadja Kirchgäßner, Jannick Heins, Sebastian Seitz, Hauke Hund, Derliz Mereles, Matthias G Friedrich, Hugo A Katus, Norbert Frey, Florian André, Marco M Ochs
{"title":"Safety of Stress Cardiac Magnetic Resonance in Patients With Moderate to Severe Aortic Valve Stenosis.","authors":"Janek Salatzki,&nbsp;Andreas Ochs,&nbsp;Nadja Kirchgäßner,&nbsp;Jannick Heins,&nbsp;Sebastian Seitz,&nbsp;Hauke Hund,&nbsp;Derliz Mereles,&nbsp;Matthias G Friedrich,&nbsp;Hugo A Katus,&nbsp;Norbert Frey,&nbsp;Florian André,&nbsp;Marco M Ochs","doi":"10.4250/jcvi.2022.0063","DOIUrl":"https://doi.org/10.4250/jcvi.2022.0063","url":null,"abstract":"<p><strong>Background: </strong>Dobutamine and adenosine stress cardiac magnetic resonance (CMR) imaging is relatively contraindicated in patients with moderate to severe aortic valve stenosis (AS). We aimed to determine the safety of dobutamine and adenosine stress CMR in patients with moderate to severe AS.</p><p><strong>Methods: </strong>In this retrospective study patients with AS who underwent either dobutamine or adenosine stress CMR for exclusion of obstructive coronary artery disease were enrolled. We recorded clinical data, CMR and echocardiography findings, and complications as well as minor symptoms. Patients with AS were compared to matched individuals without AS.</p><p><strong>Results: </strong>A total of 187 patients with AS were identified and compared to age-, gender- and body mass index-matched 187 patients without AS. No severe complications were reported in the study nor the control group. The reported frequency of non-severe complications and minor symptoms were similar between the study and the control groups. Nineteen patients with AS experienced non-severe complications or minor symptoms during dobutamine stress CMR compared to eighteen patients without AS (p = 0.855). One patient with AS and two patients without AS undergoing adenosine stress CMR experienced minor symptoms (p = 0.562). Four examinations were aborted because of chest pain, paroxysmal atrial fibrillation and third-degree atrioventricular block. Inducible ischaemia, prior coronary artery bypass grafting, prior stroke and age were associated with a higher incidence of complications and minor symptoms.</p><p><strong>Conclusions: </strong>Moderate to severe AS was not associated with complications during CMR stress test. The incidence of non-severe complications and minor symptoms was greater with dobutamine.</p>","PeriodicalId":15229,"journal":{"name":"Journal of Cardiovascular Imaging","volume":"31 1","pages":"26-38"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/99/e1/jcvi-31-26.PMC9880345.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10667990","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Right Ventricular Performance in Uncontrolled Hypertensive Patients: 2D vs. 4D Echo Study. 未受控制的高血压患者的右心室功能:二维与四维回波研究。
Journal of Cardiovascular Imaging Pub Date : 2022-10-01 DOI: 10.4250/jcvi.2022.0070
Sang Jin Ha
{"title":"Right Ventricular Performance in Uncontrolled Hypertensive Patients: 2D vs. 4D Echo Study.","authors":"Sang Jin Ha","doi":"10.4250/jcvi.2022.0070","DOIUrl":"10.4250/jcvi.2022.0070","url":null,"abstract":"","PeriodicalId":15229,"journal":{"name":"Journal of Cardiovascular Imaging","volume":"30 4","pages":"290-291"},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/ee/05/jcvi-30-290.PMC9592246.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40585695","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Do We Really Need to Predict Paravalvular Regurgitation After TAVI With Aortic Valve Calcium Load Before the Procedure? 我们真的需要在术前通过主动脉瓣钙负荷来预测 TAVI 术后瓣下反流吗?
Journal of Cardiovascular Imaging Pub Date : 2022-10-01 DOI: 10.4250/jcvi.2022.0075
Woo-Baek Chung
{"title":"Do We Really Need to Predict Paravalvular Regurgitation After TAVI With Aortic Valve Calcium Load Before the Procedure?","authors":"Woo-Baek Chung","doi":"10.4250/jcvi.2022.0075","DOIUrl":"10.4250/jcvi.2022.0075","url":null,"abstract":"","PeriodicalId":15229,"journal":{"name":"Journal of Cardiovascular Imaging","volume":"30 4","pages":"305-306"},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/16/80/jcvi-30-305.PMC9592248.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40585696","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Distribution of Aortic Root Calcium in Relation to Frame Expansion and Paravalvular Leakage After Transcatheter Aortic Valve Implantation (TAVI): An Observational Study Using a Patient-specific Contrast Attenuation Coefficient for Calcium Definition and Independent Core Lab Analysis of Paravalvular Leakage. 经导管主动脉瓣植入术(TAVI)后主动脉根部钙分布与框架扩张和瓣旁渗漏的关系:一项使用患者特异性对比衰减系数来定义钙的观察性研究和瓣旁渗漏的独立核心实验室分析。
Journal of Cardiovascular Imaging Pub Date : 2022-10-01 DOI: 10.4250/jcvi.2021.0141
Nahid El Faquir, Quinten Wolff, Rafi Sakhi, Ben Ren, Zouhair Rahhab, Sander van Weenen, Patrick Geeve, Ricardo P J Budde, Eric Boersma, Joost Daemen, Nicolas M van Mieghem, Peter P de Jaegere
{"title":"Distribution of Aortic Root Calcium in Relation to Frame Expansion and Paravalvular Leakage After Transcatheter Aortic Valve Implantation (TAVI): An Observational Study Using a Patient-specific Contrast Attenuation Coefficient for Calcium Definition and Independent Core Lab Analysis of Paravalvular Leakage.","authors":"Nahid El Faquir,&nbsp;Quinten Wolff,&nbsp;Rafi Sakhi,&nbsp;Ben Ren,&nbsp;Zouhair Rahhab,&nbsp;Sander van Weenen,&nbsp;Patrick Geeve,&nbsp;Ricardo P J Budde,&nbsp;Eric Boersma,&nbsp;Joost Daemen,&nbsp;Nicolas M van Mieghem,&nbsp;Peter P de Jaegere","doi":"10.4250/jcvi.2021.0141","DOIUrl":"https://doi.org/10.4250/jcvi.2021.0141","url":null,"abstract":"<p><strong>Background: </strong>Calcium is a determinant of paravalvular leakage (PVL) after transcatheter aortic valve implantation (TAVI). This is based on a fixed contrast attenuation value while X-ray attenuation is patient-dependent and without considering frame expansion and PVL location. We examined the role of calcium in (site-specific) PVL after TAVI using a patient-specific contrast attenuation coefficient combined with frame expansion.</p><p><strong>Methods: </strong>57 patients were included with baseline CT, post-TAVI transthoracic echocardiography and rotational angiography (R-angio). Calcium load was assessed using a patient-specific contrast attenuation coefficient. Baseline CT and post-TAVI R-angio were fused to assess frame expansion. PVL was assessed by a core lab.</p><p><strong>Results: </strong>Overall, the highest calcium load was at the non-coronary-cusp-region (NCR, 436 mm<sup>3</sup>) vs. the right-coronary-cusp-region (RCR, 233 mm<sup>3</sup>) and the left-coronary-cusp-region (LCR, 244 mm<sup>3</sup>), p < 0.001. Calcium load was higher in patients with vs. without PVL (1,137 vs. 742 mm<sup>3</sup>, p = 0.012) and was an independent predictor of PVL (odds ratio, 4.83, p = 0.004). PVL was seen most often in the LCR (39% vs. 21% [RCR] and 19% [NCR]). The degree of frame expansion was 71% at the NCR, 70% at the RCR and 74% at the LCR without difference between patients with or without PVL.</p><p><strong>Conclusions: </strong>Calcium load was higher in patients with PVL and was an independent predictor of PVL. While calcium was predominantly seen at the NCR, PVL was most often at the LCR. These findings indicate that in addition to calcium, specific anatomic features play a role in PVL after TAVI.</p>","PeriodicalId":15229,"journal":{"name":"Journal of Cardiovascular Imaging","volume":"30 4","pages":"292-304"},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/e7/31/jcvi-30-292.PMC9592252.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40585697","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Multiparametric Cardiac Magnetic Resonance Imaging Detects Altered Myocardial Tissue and Function in Heart Transplantation Recipients Monitored for Cardiac Allograft Vasculopathy. 多参数心脏磁共振成像检测心脏移植受者心肌组织和功能的改变,监测心脏移植血管病变。
Journal of Cardiovascular Imaging Pub Date : 2022-10-01 DOI: 10.4250/jcvi.2022.0003
Muhannad A Abbasi, Allison M Blake, Roberto Sarnari, Daniel Lee, Allen S Anderson, Kambiz Ghafourian, Sadiya S Khan, Esther E Vorovich, Jonathan D Rich, Jane E Wilcox, Clyde W Yancy, James C Carr, Michael Markl
{"title":"Multiparametric Cardiac Magnetic Resonance Imaging Detects Altered Myocardial Tissue and Function in Heart Transplantation Recipients Monitored for Cardiac Allograft Vasculopathy.","authors":"Muhannad A Abbasi,&nbsp;Allison M Blake,&nbsp;Roberto Sarnari,&nbsp;Daniel Lee,&nbsp;Allen S Anderson,&nbsp;Kambiz Ghafourian,&nbsp;Sadiya S Khan,&nbsp;Esther E Vorovich,&nbsp;Jonathan D Rich,&nbsp;Jane E Wilcox,&nbsp;Clyde W Yancy,&nbsp;James C Carr,&nbsp;Michael Markl","doi":"10.4250/jcvi.2022.0003","DOIUrl":"https://doi.org/10.4250/jcvi.2022.0003","url":null,"abstract":"<p><strong>Background: </strong>Cardiac allograft vasculopathy (CAV) is a complication beyond the first-year post-heart transplantation (HTx). We aimed to test the utility of cardiac magnetic resonance (CMR) to detect functional/structural changes in HTx recipients with CAV.</p><p><strong>Methods: </strong>Seventy-seven prospectively recruited HTx recipients beyond the first-year post-HTx and 18 healthy controls underwent CMR, including cine imaging of ventricular function and T1- and T2-mapping to assess myocardial tissue changes. Data analysis included quantification of global cardiac function and regional T2, T1 and extracellular volume based on the 16-segment model. International Society for Heart and Lung Transplantation criteria was used to adjudicate CAV grade (0-3) based on coronary angiography.</p><p><strong>Results: </strong>The majority of HTx recipients (73%) presented with CAV (1: n = 42, 2/3: n = 14, 0: n = 21). Global and segmental T2 (49.5 ± 3.4 ms vs 50.6 ± 3.4 ms, p < 0.001;16/16 segments) were significantly elevated in CAV-0 compared to controls. When comparing CAV-2/3 to CAV-1, global and segmental T2 were significantly increased (53.6 ± 3.2 ms vs. 50.6 ± 2.9 ms, p < 0.001; 16/16 segments) and left ventricular ejection fraction was significantly decreased (54 ± 9% vs. 59 ± 9%, p < 0.05). No global, structural, or functional differences were seen between CAV-0 and CAV-1.</p><p><strong>Conclusions: </strong>Transplanted hearts display functional and structural alteration compared to native hearts, even in those without evidence of macrovasculopathy (CAV-0). In addition, CMR tissue parameters were sensitive to changes in CAV-1 vs. 2/3 (mild vs. moderate/severe). Further studies are warranted to evaluate the diagnostic value of CMR for the detection and classification of CAV.</p>","PeriodicalId":15229,"journal":{"name":"Journal of Cardiovascular Imaging","volume":"30 4","pages":"263-275"},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/6c/51/jcvi-30-263.PMC9592247.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40585693","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
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