Journal of Burn Care & Research最新文献_第6页

Artificial Intelligence in Burn and Wound Care: Image Analysis, Prediction, and Clinical Integration. 烧伤和伤口护理中的人工智能：图像分析、预测和临床整合。

IF 1.9 4区医学

Journal of Burn Care & Research Pub Date : 2026-09-08 DOI: 10.1093/jbcr/irag090

Joshua Khorsandi, Jason Mirharooni, Justin Kahen, Ezzah Tariq, Michael Harouni, Demitri Franzoni, Joshua MacDavid

{"title":"Artificial Intelligence in Burn and Wound Care: Image Analysis, Prediction, and Clinical Integration.","authors":"Joshua Khorsandi, Jason Mirharooni, Justin Kahen, Ezzah Tariq, Michael Harouni, Demitri Franzoni, Joshua MacDavid","doi":"10.1093/jbcr/irag090","DOIUrl":"10.1093/jbcr/irag090","url":null,"abstract":"Burn injuries and chronic wounds impose a substantial and growing global health and economic burden, particularly in low- and middle-income countries and among aging populations with diabetes, vascular disease, and immobility. Conventional wound assessment depends heavily on visual inspection, manual measurements, and clinician experience, leading to variability in burn-depth estimation, wound sizing, and prognostication. Artificial intelligence, especially deep learning-based computer vision, has emerged as a promising approach to provide objective, reproducible, and scalable evaluation of burns and complex wounds. In this narrative review, we synthesize studies published between 2015 and 2025 focused on 3 domains: image-based wound recognition and segmentation, predictive modeling of outcomes such as healing, graft success, infection, and amputation, and integration of artificial intelligence into telemedicine platforms and smart technologies for remote monitoring. Across multiple datasets, convolutional neural networks achieve segmentation Dice coefficients frequently exceeding 0.85 and burn-depth or tissue-type classification sensitivities above 0.90, while multimodal prediction models reach accuracies and areas under the receiver operating characteristic curve of approximately 0.80-0.95. Early clinical pilots demonstrate the feasibility of embedding artificial intelligence tools into smartphone applications, telehealth workflows, and sensor-enabled dressings. Nonetheless, persistent challenges related to algorithmic bias across skin tones, limited dataset diversity, opaque model behavior, workflow integration, and evolving regulatory frameworks must be addressed before artificial intelligence-enabled wound care systems can be safely and equitably deployed at scale.","PeriodicalId":15205,"journal":{"name":"Journal of Burn Care & Research","volume":" ","pages":"1331-1338"},"PeriodicalIF":1.9,"publicationDate":"2026-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13551612/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148199109","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Hot and Cold: Malignant Hyperthermia Without Fever in a Burn Patient. 热与冷：烧伤患者无发热的恶性高热。

IF 1.9 4区医学

Journal of Burn Care & Research Pub Date : 2026-09-08 DOI: 10.1093/jbcr/irag077

Chloe K Nobuhara, Pooja Yesantharao, Jesse Tai, Deepak Gupta, Scott Ahlbrand, Clifford Sheckter

引用次数: 0

Care at Burn Centers Is Associated With Reduced Discharge Against Medical Advice: A National, Multi-Database Analysis. 烧伤中心的护理与减少出院有关：一项全国多数据库分析。

IF 1.9 4区医学

Journal of Burn Care & Research Pub Date : 2026-09-08 DOI: 10.1093/jbcr/irag089

Jennifer K Shah, Mollie B Smith, Clifford C Sheckter

{"title":"Care at Burn Centers Is Associated With Reduced Discharge Against Medical Advice: A National, Multi-Database Analysis.","authors":"Jennifer K Shah, Mollie B Smith, Clifford C Sheckter","doi":"10.1093/jbcr/irag089","DOIUrl":"10.1093/jbcr/irag089","url":null,"abstract":"Discharge against medical advice (AMA) leads to worse outcomes in patients with burn injuries, including higher readmission rates, wound complications, and elevated costs, although protective and risk factors remain incompletely characterized. Burn encounters were identified in 2 national databases, the Nationwide Inpatient Sample (NIS), 2016-2021, and the Burn Care Quality Platform (BCQP), 2016-2022. Encounters were stratified by AMA discharge. The primary outcomes were the overall incidence of AMA discharge and the effects of inpatient psychosocial or behavioral interventions and burn center status on AMA discharge, evaluated with 1:1 nearest-neighbor propensity-score matching of AMA and non-AMA encounters on demographics, burn characteristics, and established risk factors for AMA discharge, without replacement and with a maximum caliper distance of 0.1. In the NIS and BCQP, 5950 (2.8%) of 214 390 and 2923 (1.4%) of 205 993 burn encounters, respectively, were discharged AMA. Significant predictors of AMA discharge included male sex, Medicaid or self-pay insurance status, smaller burn size, and a more recent admission year (P < .01). The incidence of AMA discharge increased over the study period in both the NIS (incidence rate ratio [IRR] 1.2; 95% CI, 1.1-1.2; P < .01) and the BCQP (IRR 1.2; 95% CI, 1.2-1.2; P < .01). Within a propensity-score matched model, burn center care was associated with a 1.2% decrease in AMA discharge (average treatment effect, -0.01; 95% CI, -0.02 to -0.00; P = .01); psychosocial or behavioral interventions did not impact the likelihood of AMA discharge (P = .85). Existing interventions to mitigate AMA discharge are insufficient to significantly alter these patterns. Treatment at a burn center may result in a lower likelihood of AMA discharge in patients with burn injuries.","PeriodicalId":15205,"journal":{"name":"Journal of Burn Care & Research","volume":" ","pages":"1322-1330"},"PeriodicalIF":1.9,"publicationDate":"2026-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148198952","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Oral ketamine adjunct for wound care in patients with burn injuries. 口服氯胺酮辅助烧伤患者伤口护理。

IF 1.9 4区医学

Journal of Burn Care & Research Pub Date : 2026-09-04 DOI: 10.1093/jbcr/irag159

Spencer Hayashi, Sierra Young, Erin Louie, Soman Sen

{"title":"Oral ketamine adjunct for wound care in patients with burn injuries.","authors":"Spencer Hayashi, Sierra Young, Erin Louie, Soman Sen","doi":"10.1093/jbcr/irag159","DOIUrl":"https://doi.org/10.1093/jbcr/irag159","url":null,"abstract":"Opioids and benzodiazepines provide the foundation for procedural sedation during wound care following burn injury. Ketamine has been used as an adjunct and may limit exposure to opioids. Few data are published describing the use of oral ketamine in this population. This study was performed to compare the effects of oral ketamine on opioid and benzodiazepine requirements during wound care following burn injury. This was a retrospective, single center cohort study (August 2022-2024). The electronic medical record was queried for adult (≥18 years) patients admitted to the burn intensive care unit who received oral ketamine as a premedication for wound care. The primary outcome was oral morphine equivalents (OMEs) before (pre) and after (post) initiation of oral ketamine. Only medications used during wound care were recorded. Descriptive statistics were utilized for analysis. A total of 52 patients were included. The median percent total body surface area (%TBSA) burned was 31 (IQR 20-48). The median ketamine dose received during wound care was 100 mg (IQR 100-125). All patients received IV fentanyl and 47 (90%) received IV midazolam. Patients received a median of 225 mg (IQR 150-300) vs 180 mg (IQR 120-240) (P=0.008) of OMEs in the pre- and post-groups, respectively. There was no difference in midazolam received (6 mg [IQR 4-8] vs 5 mg [IQR 3-8]; P = 0.21). Oral ketamine may be an effective adjunct to wound care following burn injury and may reduce exposure to opioids.","PeriodicalId":15205,"journal":{"name":"Journal of Burn Care & Research","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2026-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148891310","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Donor Site Scarring and Dyspigmentation Following Split-Thickness Skin Graft Procedure: A Large-Sample, Single-Site Retrospective Study. 裂厚皮肤移植术后供区瘢痕和色素沉着：一项大样本、单部位回顾性研究。

IF 1.9 4区医学

Journal of Burn Care & Research Pub Date : 2026-09-03 DOI: 10.1093/jbcr/irag158

Sakura Helm, Sigrid A Blome-Eberwein

{"title":"Donor Site Scarring and Dyspigmentation Following Split-Thickness Skin Graft Procedure: A Large-Sample, Single-Site Retrospective Study.","authors":"Sakura Helm, Sigrid A Blome-Eberwein","doi":"10.1093/jbcr/irag158","DOIUrl":"https://doi.org/10.1093/jbcr/irag158","url":null,"abstract":"Split-thickness skin grafts are essential for managing burns and non-healing wounds, but donor site complications such as dyspigmentation and hypertrophic features can impair long-term donor site appearance. Evidence on risk factors for donor site morbidity in large, diverse populations is limited. This retrospective study reviewed medical records of 1,021 patients who underwent split-thickness skin graft procedures at a regional burn center from 2015 to 2024, including 559 patients with at least one postoperative follow-up visit documenting donor site appearance. Patient demographics, surgical characteristics, and donor site appearances were analyzed to identify risk factors. Fitzpatrick skin types IV, V, and VI accounted for 46.6% of patients presenting with hypertrophic features (P < .001), despite comprising 14.7% of the patient population. Older age (OR = 1.017 per year, P < .001) and a Body Mass Index ≥ 25 (OR = 2.00, P < .001) were associated with higher odds of dyspigmented donor sites. Diabetes and hypertension together elevated dyspigmentation risk (OR = 2.71, P < .001), with hypertension alone nearly doubling the risk (OR = 1.92, P < .001). Calcium alginate and silver dressings were associated with lower odds of dyspigmentation (OR = 0.368, P < .001), whereas film-only dressings more than doubled the risk (OR = 2.31, P < .001). Graft thickness and healing time were not statistically significant. These findings highlight the need for individualized care strategies that account for patient-specific risk factors to minimize donor site morbidity and improve long-term donor site outcomes after split-thickness skin grafts.","PeriodicalId":15205,"journal":{"name":"Journal of Burn Care & Research","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2026-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148887661","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Domain-Specific Associations of Neighborhood Financial Resources and Economic Hardship with Functional Outcomes in Burn Survivors. 社区经济资源和经济困难与烧伤幸存者功能结局的特定领域关联。

IF 1.9 4区医学

Journal of Burn Care & Research Pub Date : 2026-09-01 DOI: 10.1093/jbcr/irag156

Amy R Li, Nandini Raghuraman, Tricia Kirkhart, Stephen T Wegener, Fenan S Rassu

{"title":"Domain-Specific Associations of Neighborhood Financial Resources and Economic Hardship with Functional Outcomes in Burn Survivors.","authors":"Amy R Li, Nandini Raghuraman, Tricia Kirkhart, Stephen T Wegener, Fenan S Rassu","doi":"10.1093/jbcr/irag156","DOIUrl":"https://doi.org/10.1093/jbcr/irag156","url":null,"abstract":"Neighborhood disadvantage, measured by the Area Deprivation Index (ADI), is associated with long-term outcomes in burn survivors. However, prior work has relied on global scores, which may obscure domain-specific pathways linking neighborhood context to recovery. This secondary analysis of a randomized controlled trial examined whether specific ADI domains are associated, in separate adjusted models, with pain and functional outcomes in 74 adult burn survivors. Baseline addresses were linked to nationally referenced ADI scores calculated across 239,780 U.S. block groups. Three ADI-3 domains, Financial Strength, Economic Hardship, and Educational Attainment, were tested in hierarchical regressions predicting BPI Pain Severity, PROMIS Pain Interference, and BSHS Functional Abilities, controlling for demographics. The global ADI was associated with functional abilities (ΔR2 = .085, p = .012) but not pain outcomes. Domain-specific analyses revealed that both Financial Strength (β = 2.55, p-FDR = .012) and Economic Hardship (β = -2.22, p-FDR = .031) were each associated with functional abilities after multiple comparison correction, remaining robust in sensitivity analyses. A suggestive trend was observed between Financial Strength and pain severity (β = -0.52, p-FDR = .057), but this did not survive multiple comparison correction. No associations were observed for pain interference or Educational Attainment. These findings suggest that Financial Strength and Economic Hardship were domain-specific contextual correlates of functional abilities not apparent in the global index. The null pain findings alongside significant functional associations suggest neighborhood context may be more closely associated with daily functioning than with pain perception.","PeriodicalId":15205,"journal":{"name":"Journal of Burn Care & Research","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148874371","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Integrative Analysis of Nucleotide Metabolism-Related Genes Reveals a Diagnostic Signature and In Silico Functional Disruption in Hypertrophic Scarring. 核苷酸代谢相关基因的综合分析揭示了肥厚性瘢痕的诊断特征和硅功能破坏。

IF 1.9 4区医学

Journal of Burn Care & Research Pub Date : 2026-08-29 DOI: 10.1093/jbcr/irag152

Qiyun Luo, Xia Yang, Jiangyong Shen, Meirong Yan, Xiaoni Wang, Yujie Liang, Lifeng Guan

{"title":"Integrative Analysis of Nucleotide Metabolism-Related Genes Reveals a Diagnostic Signature and In Silico Functional Disruption in Hypertrophic Scarring.","authors":"Qiyun Luo, Xia Yang, Jiangyong Shen, Meirong Yan, Xiaoni Wang, Yujie Liang, Lifeng Guan","doi":"10.1093/jbcr/irag152","DOIUrl":"https://doi.org/10.1093/jbcr/irag152","url":null,"abstract":"Hypertrophic scar (HTS) is a fibrotic skin disease characterized by excessive extracellular matrix accumulation and chronic inflammation. This study aimed to investigate cellular heterogeneity, immune alterations, and nucleotide metabolism-related biomarkers in HTS and to explore their potential mechanisms. Single-cell RNA sequencing data were analyzed using Seurat for cell clustering and annotation. Nucleotide metabolism activity was evaluated to identify key cell populations and candidate genes. Bulk transcriptomic datasets from the Gene Expression Omnibus (GEO) were used for differential expression analysis, and machine learning algorithms were applied to develop a diagnostic model. Sixteen cell clusters were identified, with macrophages showing prominent activation of nucleotide metabolism pathways and immune-related signaling. The optimal Enet + svmLinear model achieved strong predictive performance (AUC = 0.934), and SHAP analysis identified NCF1 and GPR34 as key predictive genes. These genes were also associated with immune cell infiltration. In vitro validation using THP-1-derived M2 macrophages showed that NCF1 and GPR34 promoted TGF-β1 secretion and enhanced fibroblast activation, while their knockdown reduced α-SMA and collagen I expression. Collectively, this study reveals the important role of macrophage-associated nucleotide metabolism in HTS and identifies NCF1 and GPR34 as potential biomarkers and therapeutic targets.","PeriodicalId":15205,"journal":{"name":"Journal of Burn Care & Research","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2026-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148857403","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Financial Effects of Medicaid Cuts on US Burn Care. 医疗补助削减对美国烧伤护理的财政影响。

IF 1.9 4区医学

Journal of Burn Care & Research Pub Date : 2026-08-28 DOI: 10.1093/jbcr/irag154

Jennifer K Shah, Aura S Eguizabal, Clifford C Sheckter

{"title":"The Financial Effects of Medicaid Cuts on US Burn Care.","authors":"Jennifer K Shah, Aura S Eguizabal, Clifford C Sheckter","doi":"10.1093/jbcr/irag154","DOIUrl":"https://doi.org/10.1093/jbcr/irag154","url":null,"abstract":"The federal government recently passed legislation that will significantly reduce Medicaid spending through work requirements. Burns disproportionately affect the Medicaid population and are one of the most costly injuries with some admissions incurring multimillion dollar hospital stays. All admissions with a primary burn diagnosis were extracted from the National Inpatient Sample, 2017-2022. Cost-to-charge ratios were applied and adjusted for inflation to 2025 US dollars. Facilities were stratified by burn center and safety-net status. Reductions in Medicaid enrollment were modeled using US Congressional Budget Office estimates. Projections of burn care and burn center losses over a 6-year period with 95% confidence intervals (CIs) were derived from Monte Carlo simulations using bootstrap resampling distributions. Of 178,545 weighted burn encounters, 39,575 under 18 years old were excluded as children will not be affected by the new law. The frequency of burn encounters covered by Medicaid has increased by 7.0% over the past 6 years. The total annual cost of burn care is estimated at $3,190,265,497, 28.4% of which is costs to Medicaid. Burn center costs to Medicaid increased by 18.9% over the past 6 years. Assuming the current trajectory of inpatient admissions, the overall reduction in Medicaid payments from burn care is estimated at $525,645,056-$717,992,704. 33.1% of Medicaid encounters were treated at safety-net hospitals, which will incur a 2.70% reduction in burn center funding. Non-safety-net hospitals will incur a 2.39% reduction. Revenue-generating strategies and cost containment may be insufficient for financial solvency in some burn centers.","PeriodicalId":15205,"journal":{"name":"Journal of Burn Care & Research","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2026-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148850705","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Maternal and fetal outcomes in pregnant women with burn injuries: a systematic review and Meta-analysis. 烧伤孕妇的母胎结局：系统回顾和荟萃分析。

IF 1.9 4区医学

Journal of Burn Care & Research Pub Date : 2026-08-28 DOI: 10.1093/jbcr/irag155

Juan Jose Parra Molina, Sergio Romero, Edgar Fabian Manrique Hernandez

{"title":"Maternal and fetal outcomes in pregnant women with burn injuries: a systematic review and Meta-analysis.","authors":"Juan Jose Parra Molina, Sergio Romero, Edgar Fabian Manrique Hernandez","doi":"10.1093/jbcr/irag155","DOIUrl":"https://doi.org/10.1093/jbcr/irag155","url":null,"abstract":"Burn injuries during pregnancy are associated with significant maternal and fetal morbidity and mortality; however, available evidence is fragmented and largely based on small observational studies. To estimate pooled maternal and fetal mortality among pregnant women with burn injuries and explore the impact of burn severity. A systematic review and meta-analysis of proportions was conducted following PRISMA 2020 guidelines. PubMed/MEDLINE, Scopus, Web of Science, and LILACS were searched from inception to March 2026. Observational studies and case series reporting maternal and/or fetal outcomes were included. Risk of bias was assessed using NOS and JBI tools, and certainty of evidence using GRADE. Random-effects models with Freeman-Tukey double arcsine transformation were applied. Results: Twenty-two studies including 1,162 pregnant women were analyzed. Most studies were case series (n=15), followed by cohort studies (n=5) one cross-sectional study, and one case report. Maternal mortality ranged from 0% to 70%. The pooled maternal mortality proportion was 0.43 (95% CI: 0.36.0.50), with substantial heterogeneity (I2=72.9%). Fetal mortality ranged from 31.3% to 90.5%, with a pooled estimate of 0.57 (95% CI: 0.49.0.65; I2=78.6%). Burn severity, particularly TBSA burned .50%, was consistently associated with worse outcomes. Funnel plots suggested possible publication bias. The overall certainty of evidence was low. Burn injuries during pregnancy are associated with high maternal and fetal mortality, strongly influenced by burn severity. Despite consistent findings, the low certainty of evidence highlights the need for high-quality prospective studies.","PeriodicalId":15205,"journal":{"name":"Journal of Burn Care & Research","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2026-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148850754","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Revisiting the Obesity Paradox in Burns: A Retrospective Cohort Study of Burn Patients Requiring Surgical Excision. 重新审视烧伤中的肥胖悖论：一项需要手术切除的烧伤患者的回顾性队列研究。

IF 1.9 4区医学

Journal of Burn Care & Research Pub Date : 2026-08-26 DOI: 10.1093/jbcr/irag153

J E Dvorak, C L Kohler, S Quallich, S L Cantale-Thomas, P J Maluso

{"title":"Revisiting the Obesity Paradox in Burns: A Retrospective Cohort Study of Burn Patients Requiring Surgical Excision.","authors":"J E Dvorak, C L Kohler, S Quallich, S L Cantale-Thomas, P J Maluso","doi":"10.1093/jbcr/irag153","DOIUrl":"https://doi.org/10.1093/jbcr/irag153","url":null,"abstract":"Obesity represents a significant health burden in the United States and has a significant impact on individual health, increasing the likelihood of multiple comorbidities. However, the presence of an \"obesity paradox\", in which increasing body mass index (BMI) may be protective against morbidity and mortality in certain clinical settings, has been demonstrated in both trauma and emergency general surgery patients. The impact of obesity on outcomes in burn patients is mixed, and no study has evaluated the impact of obesity on burn outcomes specifically in patients requiring excision of burn wounds. We performed a retrospective cohort study utilizing the American Burn Association's Burn Care Quality Platform dataset, of burn patients requiring surgical excision. Primary outcome was the association of obesity with mortality. Secondary outcomes included association of obesity with infection, graft loss, ventilator days, and length of stay (LOS). Multivariate regressions, controlling for pertinent variables, were used for analysis. 6,045 patients were included in the analysis, 4,999 in the non-obese cohort and 1,046 in the obese cohort. There was no association between obesity and mortality, nor was there any association between obesity and graft loss. However, obesity was associated with increased odds for infection (OR 1.20, 95% CI 1.01 - 1.42, p = 0.04), increased ventilator days (IRR 1.34, 95% CI 1.19 - 1.51, p < 0.01), and an association in the direction of increased LOS (sHR 0.93, 95% CI 0.87 - 1.00, p = 0.06). Not only was there no obesity paradox, obesity was associated with increased morbidity in patients requiring excision.","PeriodicalId":15205,"journal":{"name":"Journal of Burn Care & Research","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2026-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148818339","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0