Journal of Cardiac Failure最新文献

{"title":"Reprieve System for the Treatment of Patients With Acute Decompensated Heart Failure.","authors":"Juan B Ivey-Miranda, Veena S Rao, Tamaz Shaburishvili, Ivlita Verulava, Nina Khabeishvili, Mark C Petrie, Javed Butler, Julio Nunez, Jan Biegus, Piotr Ponikowski, Kevin Damman, Sean P Collins, Jeffrey M Testani, Zachary L Cox","doi":"10.1016/j.cardfail.2025.02.002","DOIUrl":"10.1016/j.cardfail.2025.02.002","url":null,"abstract":"","PeriodicalId":15204,"journal":{"name":"Journal of Cardiac Failure","volume":" ","pages":""},"PeriodicalIF":6.7,"publicationDate":"2025-02-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143414432","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Underpinnings of Heart Failure With Preserved Ejection Fraction in Women - From Prevention to Improving Function. A Co-publication With the American Journal of Preventive Cardiology and the Journal of Cardiac Failure.","authors":"Ankitha Radakrishnan, Saloni Agrawal, Nausheen Singh, Anna Barbieri, Leslee J Shaw, Martha Gulati, Anuradha Lala","doi":"10.1016/j.cardfail.2025.01.008","DOIUrl":"https://doi.org/10.1016/j.cardfail.2025.01.008","url":null,"abstract":"<p><p>Heart failure with preserved ejection fraction (HFpEF) represents a major clinical challenge with rising global prevalence. Women have a nearly double lifetime risk of developing HFpEF compared to heart failure with reduced ejection fraction (HFrEF). In HFpEF, sex differences emerge both in how traditional cardiovascular risk factors (such as hypertension, obesity, and diabetes) affect cardiac function and through distinct pathophysiological mechanisms triggered by sex-specific events like menopause and adverse pregnancy outcomes. These patterns influence not only disease development, but also therapeutic responses, necessitating sex-specific approaches to treatment. This review aims to synthesize existing knowledge regarding HFpEF in women including traditional and sex-specific risk factors, pathophysiology, presentation, and therapies, while outlining important knowledge gaps that warrant further investigation. The impact of HFpEF spans a woman's entire lifespan, requiring prevention and management strategies tailored to different life stages. While understanding of sex-based differences in HFpEF has improved, significant knowledge gaps persist. Through examination of current evidence and challenges, this review highlights promising opportunities for innovative research, therapeutic development, and clinical care approaches that could transform the management of HFpEF in women.</p>","PeriodicalId":15204,"journal":{"name":"Journal of Cardiac Failure","volume":" ","pages":""},"PeriodicalIF":6.7,"publicationDate":"2025-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143458132","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Emerging Myth of Primary Graft Dysfunction in the Era of Advanced Organ Preservation in Heart Transplantation.","authors":"Nicole K Bart, Andreas Zuckermann, Mandeep R Mehra","doi":"10.1016/j.cardfail.2025.01.013","DOIUrl":"10.1016/j.cardfail.2025.01.013","url":null,"abstract":"","PeriodicalId":15204,"journal":{"name":"Journal of Cardiac Failure","volume":" ","pages":""},"PeriodicalIF":6.7,"publicationDate":"2025-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143373809","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluating Incident Atrial Fibrillation and Incident Heart Failure as Time-varying Covariates for Time-to-Event Analysis Among Adults 55 Years and Older in the Multi-Ethnic Study of Atherosclerosis (MESA).","authors":"Pierre J Amiel, Bharath Ambale-Venkatesh, Colin O Wu, Matthew Matheson, Mohammad R Ostovaneh, João A C Lima, Christopher F Cox","doi":"10.1016/j.cardfail.2025.01.012","DOIUrl":"10.1016/j.cardfail.2025.01.012","url":null,"abstract":"<p><strong>Objectives: </strong>Heart failure (HF) and atrial fibrillation (AF) frequently coexist, exacerbate each other and are associated with increased morbidity and mortality rates. However, no previous study has specifically calculated the risk of experiencing either event following the occurrence of the other and also considered competing risks. The aim of this study was to examine the bidirectional relationship of AF and HF in a multiethnic population, taking competing risks into account.</p><p><strong>Methods: </strong>Two Fine and Gray regression models of the subdistribution functions were implemented to evaluate the bidirectional association between AF and HF and were adjusted for a common set of covariates. Competing events were defined as HF/AF and/or cardiac death vs noncardiac death. For each model, common covariates for AF and HF were pre-identified in the literature, and either HF or AF was used as a time-dependent covariate.</p><p><strong>Results: </strong>In the Multi-Ethnic Study of Atherosclerosis (MESA), 4016 study participants (mean age 67.2 ± 7.6 years and 48.8% male participants), free of clinically recognized cardiovascular disease at baseline, were assessed for AF and HF. After a median (IQR) follow-up of 6034 (3994-6313) days, 1044 incident AFs, 302 incident HFs and 1298 events of death occurred. Deaths were distributed as 313 cardiac deaths and 985 noncardiac deaths, and the incidence of AF was about 3.5 higher than that of HF. We found that HF was associated with a composite outcome of AF and/or cardiac death (HR 2.91, 95%CI [2.49-3.40]; P < 0.001) and that AF was associated with a composite outcome of HF and/or cardiac death (HR 2.05, 95%CI [1.79-2.35]; P < 0.001).</p><p><strong>Conclusion: </strong>AF and HF exacerbate the incidence of each other and are strongly and independently associated, suggesting that their joint association should be taken into consideration in future studies. From a clinical perspective, the occurrence of either of these events greatly increases the risk for the other (ClinicalTrials.gov Identifier: NCT00005487).</p>","PeriodicalId":15204,"journal":{"name":"Journal of Cardiac Failure","volume":" ","pages":""},"PeriodicalIF":6.7,"publicationDate":"2025-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143255700","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Editorial: Unlocking the Prognostic Potential: the Quest for Optimal Right Ventricular Parameters in LVAD Recipients","authors":"ANIQUE DUCHARME MD, MSc ,&nbsp;MOHAMMED IMRAN ASLAM MD","doi":"10.1016/j.cardfail.2024.11.004","DOIUrl":"10.1016/j.cardfail.2024.11.004","url":null,"abstract":"","PeriodicalId":15204,"journal":{"name":"Journal of Cardiac Failure","volume":"31 2","pages":"Pages 397-399"},"PeriodicalIF":6.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142638048","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ventricular Arrhythmias in Patients With Cardiac Sarcoidosis Following Left Ventricular Assist Device Implantation","authors":"FRANCISCA BERMUDEZ BS ,&nbsp;ALEXANDER A. RIZK MD ,&nbsp;MANISH H. SHAH MD ,&nbsp;FAROOQ H. SHEIKH MD ,&nbsp;CONNOR P. OATES MD","doi":"10.1016/j.cardfail.2024.10.442","DOIUrl":"10.1016/j.cardfail.2024.10.442","url":null,"abstract":"","PeriodicalId":15204,"journal":{"name":"Journal of Cardiac Failure","volume":"31 2","pages":"Pages 485-488"},"PeriodicalIF":6.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142780020","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An Unexpected Benefit of Adding the Patient Voice to Medical Education—Train Providers to Be Better","authors":"Mackenzie N. Boedicker MS, BS ,&nbsp;Deborah D. Boedicker MBA, BS","doi":"10.1016/j.cardfail.2024.12.007","DOIUrl":"10.1016/j.cardfail.2024.12.007","url":null,"abstract":"<div><h3>Background</h3><div>Amyloidosis is a complex multisystemic disease. Lack of knowledge about amyloidosis and subsequent misdiagnosis or underdiagnosis are major obstacles to treatment that result in life-threatening organ damage, heart failure, morbidity, and mortality. At present, medical didactic education about amyloidosis leaves new physicians woefully unprepared to suspect and diagnose it. A study published in 2023 confirmed a positive impact on medical students following a patient presentation. Continued analysis of the study data revealed an unexpected benefit of adding the patient voice to medical education. The purpose of this paper is to describe this unexpected and potentially powerful benefit.</div></div><div><h3>Methods and Results</h3><div>The Amyloidosis Speakers Bureau (ASB), founded in 2019, arranges for ASB patient educators to speak about their diagnostic and treatment experiences with medical students. In 2023, we published a study to understand the impact from the addition of the patient voice to didactic medical education. The study concluded that listening to an ASB patient educator's narrative was associated with positive attitudes toward communication with patients, interest in acquiring and applying knowledge of amyloidosis, and humility about diagnosis. Post-publishing, continued analysis of the presentation feedback made it clear that another benefit was occurring. During the ASB presentations, questions were repeatedly raised about what guidance the patients might offer to help these budding doctors become better providers and how they could improve their relationships with patients. Their inquiries had nothing to do with amyloidosis and were relevant to every interaction and all diseases. These future providers wanted to be better and wanted the patient's perspective to help get there. Assessing their questions revealed an unexpected benefit from the patient presentations.</div></div><div><h3>Conclusion</h3><div>ASB patient educators contributed to humanizing medical education. From this, the students gained insights to help them become better providers.</div></div>","PeriodicalId":15204,"journal":{"name":"Journal of Cardiac Failure","volume":"31 2","pages":"Pages 492-494"},"PeriodicalIF":6.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142949404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Point: Natriuresis Guided Diuresis in Patients Admitted to Hospital With Heart Failure – Barking up the Wrong Tree","authors":"JJ CUTHBERT MD ,&nbsp;JGF CLELAND MD ,&nbsp;P PELLICORI MD ,&nbsp;AL CLARK MD","doi":"10.1016/j.cardfail.2024.09.021","DOIUrl":"10.1016/j.cardfail.2024.09.021","url":null,"abstract":"","PeriodicalId":15204,"journal":{"name":"Journal of Cardiac Failure","volume":"31 2","pages":"Pages 465-468"},"PeriodicalIF":6.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142785845","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Digital Health: From Remote Monitoring to Remote Care","authors":"MARAT FUDIM MD, MHS ,&nbsp;DAVID I. FELDMAN MD, MPH ,&nbsp;AHMED SAYED MBBS","doi":"10.1016/j.cardfail.2024.08.033","DOIUrl":"10.1016/j.cardfail.2024.08.033","url":null,"abstract":"<div><div>The growth of digital health technology has led to innovative technological solutions that can help to improve patient care. However, the primary focus to date has been on the passive monitoring of patients, which poses difficulties in clinical integration and has not succeeded in optimizing care for chronic conditions. In this article, we highlight the move from a digital care model focused on the passive monitoring of medical conditions to one where holistic patient management is provided by dedicated external health care teams on a longitudinal basis. This underlines the shift from remote patient monitoring to remote patient care. This approach has thus far mostly been applied at small scales, limited to specific institutions and environments. Generalization to the wider population will likely require the use of centralized entities that can scale these approaches. It is crucial to note that the role of this technology will be to supplement, rather than supplant, in-person care by allowing physicians to focus on the most relevant clinical data collected on a longitudinal basis. This approach is particularly promising for individuals living in rural or underserved areas, where traditional models of care may face barriers in implementation.</div></div>","PeriodicalId":15204,"journal":{"name":"Journal of Cardiac Failure","volume":"31 2","pages":"Pages 489-491"},"PeriodicalIF":6.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142017577","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cardio-Oncology and Heart Failure: a Scientific Statement From the Heart Failure Society of America","authors":"MICHELLE WEISFELNER BLOOM MD, Co-Chair ,&nbsp;JACQUELINE B. VO PhD, RN, MPH ,&nbsp;JO E. RODGERS PharmD, BCPS, BCCP ,&nbsp;ALANA M. FERRARI PharmD, BCOP ,&nbsp;ANJU NOHRIA MD, MSc ,&nbsp;ANITA DESWAL MD, MPH ,&nbsp;RICHARD K. CHENG MD, MSc ,&nbsp;MICHELLE M. KITTLESON MD, PhD ,&nbsp;JENICA N. UPSHAW MD, MS ,&nbsp;NICOLAS PALASKAS MD ,&nbsp;ANNE BLAES MD, MS ,&nbsp;SHERRY-ANN BROWN MD, PhD ,&nbsp;BONNIE KY MD, MSCE ,&nbsp;DANIEL LENIHAN MD ,&nbsp;MATHEW S. MAURER MD ,&nbsp;ANECITA FADOL PhD, NP ,&nbsp;KERRY SKURKA RN, BSN ,&nbsp;CHRISTINE CAMBARERI PharmD, BCOP ,&nbsp;CYNTHIA CHAUHAN MSW ,&nbsp;ANA BARAC MD, PhD (Co-Chair)","doi":"10.1016/j.cardfail.2024.08.045","DOIUrl":"10.1016/j.cardfail.2024.08.045","url":null,"abstract":"<div><div>Heart failure and cancer remain 2 of the leading causes of morbidity and mortality, and the 2 disease entities are linked in a complex manner. Patients with cancer are at increased risk of cardiovascular complications related to the cancer therapies. The presence of cardiomyopathy or heart failure in a patient with new cancer diagnosis portends a high risk for adverse oncology and cardiovascular outcomes. With the rapid growth of cancer therapies, many of which interfere with cardiovascular homeostasis, heart failure practitioners need to be familiar with prevention, risk stratification, diagnosis, and management strategies in cardio-oncology.</div><div>This Heart Failure Society of America statement addresses the complexities of heart failure care among patients with active cancer diagnoses and cancer survivors. Risk stratification, monitoring and management of cardiotoxicity are presented across stages A through D heart failure, with focused discussion on heart failure with preserved ejection fraction and special populations, such as survivors of childhood and young-adulthood cancers. We provide an overview of the shared risk factors between cancer and heart failure, highlighting heart failure as a form of cardiotoxicity associated with many different cancer therapeutics. Finally, we discuss disparities in the care of patients with cancer and cardiac disease and present a framework for a multidisciplinary-team approach and critical collaboration among heart failure, oncology, palliative care, pharmacy, and nursing teams in the management of these complex patients.</div></div>","PeriodicalId":15204,"journal":{"name":"Journal of Cardiac Failure","volume":"31 2","pages":"Pages 415-455"},"PeriodicalIF":6.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142466330","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}