Journal of Cardiac Failure最新文献

{"title":"An Unexpected Benefit of Adding the Patient Voice to Medical Education—Train Providers to Be Better","authors":"Mackenzie N. Boedicker MS, BS ,&nbsp;Deborah D. Boedicker MBA, BS","doi":"10.1016/j.cardfail.2024.12.007","DOIUrl":"10.1016/j.cardfail.2024.12.007","url":null,"abstract":"<div><h3>Background</h3><div>Amyloidosis is a complex multisystemic disease. Lack of knowledge about amyloidosis and subsequent misdiagnosis or underdiagnosis are major obstacles to treatment that result in life-threatening organ damage, heart failure, morbidity, and mortality. At present, medical didactic education about amyloidosis leaves new physicians woefully unprepared to suspect and diagnose it. A study published in 2023 confirmed a positive impact on medical students following a patient presentation. Continued analysis of the study data revealed an unexpected benefit of adding the patient voice to medical education. The purpose of this paper is to describe this unexpected and potentially powerful benefit.</div></div><div><h3>Methods and Results</h3><div>The Amyloidosis Speakers Bureau (ASB), founded in 2019, arranges for ASB patient educators to speak about their diagnostic and treatment experiences with medical students. In 2023, we published a study to understand the impact from the addition of the patient voice to didactic medical education. The study concluded that listening to an ASB patient educator's narrative was associated with positive attitudes toward communication with patients, interest in acquiring and applying knowledge of amyloidosis, and humility about diagnosis. Post-publishing, continued analysis of the presentation feedback made it clear that another benefit was occurring. During the ASB presentations, questions were repeatedly raised about what guidance the patients might offer to help these budding doctors become better providers and how they could improve their relationships with patients. Their inquiries had nothing to do with amyloidosis and were relevant to every interaction and all diseases. These future providers wanted to be better and wanted the patient's perspective to help get there. Assessing their questions revealed an unexpected benefit from the patient presentations.</div></div><div><h3>Conclusion</h3><div>ASB patient educators contributed to humanizing medical education. From this, the students gained insights to help them become better providers.</div></div>","PeriodicalId":15204,"journal":{"name":"Journal of Cardiac Failure","volume":"31 2","pages":"Pages 492-494"},"PeriodicalIF":6.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142949404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Point: Natriuresis Guided Diuresis in Patients Admitted to Hospital With Heart Failure – Barking up the Wrong Tree","authors":"JJ CUTHBERT MD ,&nbsp;JGF CLELAND MD ,&nbsp;P PELLICORI MD ,&nbsp;AL CLARK MD","doi":"10.1016/j.cardfail.2024.09.021","DOIUrl":"10.1016/j.cardfail.2024.09.021","url":null,"abstract":"","PeriodicalId":15204,"journal":{"name":"Journal of Cardiac Failure","volume":"31 2","pages":"Pages 465-468"},"PeriodicalIF":6.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142785845","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Digital Health: From Remote Monitoring to Remote Care","authors":"MARAT FUDIM MD, MHS ,&nbsp;DAVID I. FELDMAN MD, MPH ,&nbsp;AHMED SAYED MBBS","doi":"10.1016/j.cardfail.2024.08.033","DOIUrl":"10.1016/j.cardfail.2024.08.033","url":null,"abstract":"<div><div>The growth of digital health technology has led to innovative technological solutions that can help to improve patient care. However, the primary focus to date has been on the passive monitoring of patients, which poses difficulties in clinical integration and has not succeeded in optimizing care for chronic conditions. In this article, we highlight the move from a digital care model focused on the passive monitoring of medical conditions to one where holistic patient management is provided by dedicated external health care teams on a longitudinal basis. This underlines the shift from remote patient monitoring to remote patient care. This approach has thus far mostly been applied at small scales, limited to specific institutions and environments. Generalization to the wider population will likely require the use of centralized entities that can scale these approaches. It is crucial to note that the role of this technology will be to supplement, rather than supplant, in-person care by allowing physicians to focus on the most relevant clinical data collected on a longitudinal basis. This approach is particularly promising for individuals living in rural or underserved areas, where traditional models of care may face barriers in implementation.</div></div>","PeriodicalId":15204,"journal":{"name":"Journal of Cardiac Failure","volume":"31 2","pages":"Pages 489-491"},"PeriodicalIF":6.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142017577","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cardio-Oncology and Heart Failure: a Scientific Statement From the Heart Failure Society of America","authors":"MICHELLE WEISFELNER BLOOM MD, Co-Chair ,&nbsp;JACQUELINE B. VO PhD, RN, MPH ,&nbsp;JO E. RODGERS PharmD, BCPS, BCCP ,&nbsp;ALANA M. FERRARI PharmD, BCOP ,&nbsp;ANJU NOHRIA MD, MSc ,&nbsp;ANITA DESWAL MD, MPH ,&nbsp;RICHARD K. CHENG MD, MSc ,&nbsp;MICHELLE M. KITTLESON MD, PhD ,&nbsp;JENICA N. UPSHAW MD, MS ,&nbsp;NICOLAS PALASKAS MD ,&nbsp;ANNE BLAES MD, MS ,&nbsp;SHERRY-ANN BROWN MD, PhD ,&nbsp;BONNIE KY MD, MSCE ,&nbsp;DANIEL LENIHAN MD ,&nbsp;MATHEW S. MAURER MD ,&nbsp;ANECITA FADOL PhD, NP ,&nbsp;KERRY SKURKA RN, BSN ,&nbsp;CHRISTINE CAMBARERI PharmD, BCOP ,&nbsp;CYNTHIA CHAUHAN MSW ,&nbsp;ANA BARAC MD, PhD (Co-Chair)","doi":"10.1016/j.cardfail.2024.08.045","DOIUrl":"10.1016/j.cardfail.2024.08.045","url":null,"abstract":"<div><div>Heart failure and cancer remain 2 of the leading causes of morbidity and mortality, and the 2 disease entities are linked in a complex manner. Patients with cancer are at increased risk of cardiovascular complications related to the cancer therapies. The presence of cardiomyopathy or heart failure in a patient with new cancer diagnosis portends a high risk for adverse oncology and cardiovascular outcomes. With the rapid growth of cancer therapies, many of which interfere with cardiovascular homeostasis, heart failure practitioners need to be familiar with prevention, risk stratification, diagnosis, and management strategies in cardio-oncology.</div><div>This Heart Failure Society of America statement addresses the complexities of heart failure care among patients with active cancer diagnoses and cancer survivors. Risk stratification, monitoring and management of cardiotoxicity are presented across stages A through D heart failure, with focused discussion on heart failure with preserved ejection fraction and special populations, such as survivors of childhood and young-adulthood cancers. We provide an overview of the shared risk factors between cancer and heart failure, highlighting heart failure as a form of cardiotoxicity associated with many different cancer therapeutics. Finally, we discuss disparities in the care of patients with cancer and cardiac disease and present a framework for a multidisciplinary-team approach and critical collaboration among heart failure, oncology, palliative care, pharmacy, and nursing teams in the management of these complex patients.</div></div>","PeriodicalId":15204,"journal":{"name":"Journal of Cardiac Failure","volume":"31 2","pages":"Pages 415-455"},"PeriodicalIF":6.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142466330","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Counterpoint: Natriuresis-Guided Diuresis in Patients Admitted to Hospital With Heart Failure – Barking Up the Wrong Tree? Towards Direct Insights Into the Efficacy of Diuretic Therapy","authors":"JOZINE M. TER MAATEN MD, PhD ,&nbsp;WILFRIED MULLENS MD, PhD","doi":"10.1016/j.cardfail.2024.11.008","DOIUrl":"10.1016/j.cardfail.2024.11.008","url":null,"abstract":"","PeriodicalId":15204,"journal":{"name":"Journal of Cardiac Failure","volume":"31 2","pages":"Pages 469-470"},"PeriodicalIF":6.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142785844","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"CHIP-ing Away at Post-Transplant Outcomes: the Role of Somatic Mutations in Heart Transplant Outcomes","authors":"JESSICA A. REGAN MD ,&nbsp;SVATI H. SHAH MD, MHS","doi":"10.1016/j.cardfail.2024.12.002","DOIUrl":"10.1016/j.cardfail.2024.12.002","url":null,"abstract":"","PeriodicalId":15204,"journal":{"name":"Journal of Cardiac Failure","volume":"31 2","pages":"Pages 411-414"},"PeriodicalIF":6.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142877253","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"From Inflammation to Inspiration and Innovation: A New Perspective on the Utility of Anti-inflammatory Therapies for Acute Heart Failure","authors":"Michael Sobieraj MD, MS ,&nbsp;Kannu Bansal MD ,&nbsp;Katherine AA Clark MD, MBA","doi":"10.1016/j.cardfail.2025.01.002","DOIUrl":"10.1016/j.cardfail.2025.01.002","url":null,"abstract":"","PeriodicalId":15204,"journal":{"name":"Journal of Cardiac Failure","volume":"31 2","pages":"Pages 367-368"},"PeriodicalIF":6.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143005805","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Effects of Burst Steroid Therapy on Short-term Decongestion in Acute Heart Failure Patients With Pro-inflammatory Activation: A Post Hoc Analysis of the CORTAHF Randomized, Open-label, Pilot Trial","authors":"JAN BIEGUS MD, PhD ,&nbsp;GAD COTTER MD ,&nbsp;BETH A. DAVISON PhD ,&nbsp;YONATHAN FREUND MD ,&nbsp;ADRIAAN A. VOORS MD, PhD ,&nbsp;CHRISTOPHER EDWARDS BS, ,&nbsp;MARIA NOVOSADOVA MD ,&nbsp;KOJI TAKAGI MD ,&nbsp;Hamlet HAYRAPETYAN MD ,&nbsp;ANDRANIK MSHETSYAN MD ,&nbsp;DRAMBYAN MAYRANUSH MD ,&nbsp;ALAIN COHEN-SOLAL MD, PhD ,&nbsp;JOZINE M. TER MAATEN MD, PhD ,&nbsp;GERASIMOS FILIPPATOS MD ,&nbsp;OVIDIU CHIONCEL MD, PhD ,&nbsp;MALHA SADOUNE MSc ,&nbsp;MATTEO PAGNESI MD, PhD ,&nbsp;TABASSOME SIMON MD ,&nbsp;MARCO METRA MD, PhD ,&nbsp;DOUGLAS L. MANN MD ,&nbsp;PIOTR PONIKOWSKI MD, PhD","doi":"10.1016/j.cardfail.2024.09.002","DOIUrl":"10.1016/j.cardfail.2024.09.002","url":null,"abstract":"<div><h3>Background</h3><div>The effect of steroids on congestion in patients with acute heart failure (AHF) is not known.</div></div><div><h3>Methods and Results</h3><div>Patients with AHF, NT-proBNP levels &gt; 1500 pg/mL and high-sensitivity C-reactive protein (hsCRP) levels &gt; 20 mg/L were randomized to once-daily oral 40 mg prednisone for 7 days or usual care. In this post hoc analysis, congestion score was calculated on the basis of orthopnea, edema and rales (0 reflecting lack of congestion, and 9 maximal congestion) at each time point. Among 100 eligible patients randomized, those assigned to prednisone had a greater improvement in congestion score at day 31 (win odds for the prednisone group compared to usual care at day 31 was 1.77 (95% CI 1.17–2.84; <em>P</em> = 0.0066) in all patients and 2.41 (95% CI 1.37–5.05; <em>P</em> = 0.0016) in patients with IL-6 &gt; 13 pg/mL at baseline. In patients with congestion scores ≥ 7 at baseline, the effects of prednisone therapy on the EQ-5D visual analog scale score were 4.30 (95% CI 0.77-7.83) points at day 7 and 5.40 (0.51–10.29) points at day 31, accompanied by lower heart rate and respiratory rate and higher oxygen saturation compared to usual care.</div></div><div><h3>Conclusions</h3><div>In patients with AHF and inflammatory activation, 7-day steroid therapy was associated with reduction in signs of congestion up to day 31. These results need confirmation in larger studies examining potential effects of steroids on congestion, diuresis, fluid redistribution and vascular permeability as well as clinical effects in AHF.</div></div>","PeriodicalId":15204,"journal":{"name":"Journal of Cardiac Failure","volume":"31 2","pages":"Pages 354-366"},"PeriodicalIF":6.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142365362","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Patient Sex Impacts Volume Phenotypes and Hemodynamics in Chronic Heart Failure: A Multicenter Analysis","authors":"MARAT FUDIM MD, MHS ,&nbsp;VERAPRAPAS KITTIPIBUL MD ,&nbsp;JEROEN MOLINGER MS ,&nbsp;DMITRY M. YARANOV MD ,&nbsp;WAYNE L. MILLER MD, PhD","doi":"10.1016/j.cardfail.2024.05.013","DOIUrl":"10.1016/j.cardfail.2024.05.013","url":null,"abstract":"<div><h3>Background</h3><div>Quantitative methods<span> have shown clinically significant heterogeneity in blood volume (BV) profiles in patients with chronic heart failure (HF). How patients’ sex might impact this volume heterogeneity and its relationship to cardiac hemodynamics remains to be defined.</span></div></div><div><h3>Methods</h3><div><span><span>Retrospective analysis of clinical and quantitative BV, plasma volume (PV) and red blood cell (RBC) mass data was undertaken across 3 medical centers. BV was quantitated using </span>nuclear medicine I-131-labeled </span>plasma albumin<span> indicator-dilution methodology with cardiac hemodynamics obtained within 24 hours.</span></div></div><div><h3>Results</h3><div>In an analysis of 149 males and 106 females, absolute BV was greater, on average, in males (6.9 ± 1.7 vs 5.0 ± 1.2 liters; P &lt; 0.001); however, a wide range in BVs was demonstrated in both sexes (2.9–14.5 liters). Male sex was associated with higher prevalence of large (+ 25% of normal) BV and PV expansions (36% vs 15% and 51% vs 21%, respectively; both P &lt; 0.001). In contrast, female sex was associated with higher prevalence of normal total BV (44% vs 27%; P = 0.005), PV (54% vs 27%; P &lt; 0.001), hypovolemia<span> (23% vs 11%; P = 0.005), and true anemia (42% vs 26%; P &lt; 0.001). Cardiac hemodynamics differed by sex, but only modest associations were demonstrated between volume profiles and cardiac filling pressures.</span></div></div><div><h3>Conclusions</h3><div>Findings support unique intravascular volume profiles reflecting sex-specific differences in the prevalence and distributions of total BV, PV and RBC mass profiles in patients with chronic HF. This underscores the importance of recognizing patients’ sex as a significant factor influencing volume homeostasis, which needs to be taken into account to individualize volume-management strategies effectively.</div></div>","PeriodicalId":15204,"journal":{"name":"Journal of Cardiac Failure","volume":"31 2","pages":"Pages 379-387"},"PeriodicalIF":6.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141330969","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical Outcomes of Chronic Intravenous Inotropic Support in Cardiac Amyloidosis","authors":"JOHANA FAJARDO DNP ,&nbsp;MAXWELL A. HOCKSTEIN MD ,&nbsp;MANAV SINGH ,&nbsp;FRANCISCA BERMUDEZ BS ,&nbsp;TANIA VORA MD ,&nbsp;AJAY KADAKKAL MD ,&nbsp;NANA AFARI-ARMAH MD ,&nbsp;RAJA ZAGHLOL MD ,&nbsp;SAMER S. NAJJAR MD ,&nbsp;ANIRUDH RAO MD ,&nbsp;FAROOQ H. SHEIKH MD","doi":"10.1016/j.cardfail.2024.07.021","DOIUrl":"10.1016/j.cardfail.2024.07.021","url":null,"abstract":"","PeriodicalId":15204,"journal":{"name":"Journal of Cardiac Failure","volume":"31 2","pages":"Pages 471-476"},"PeriodicalIF":6.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142000011","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}