Journal of Cardiac Failure最新文献

{"title":"JCF in Case You Missed It! Summary of American College of Cardiology (ACC) 2026","authors":"DIANA DE OLIVEIRA-GOMES MD, ALEXANDER HAJDUCZOK MD, ANURADHA LALA MD","doi":"10.1016/j.cardfail.2026.04.014","DOIUrl":"10.1016/j.cardfail.2026.04.014","url":null,"abstract":"","PeriodicalId":15204,"journal":{"name":"Journal of Cardiac Failure","volume":"32 10","pages":"Pages 1816-1820"},"PeriodicalIF":9.9,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148251679","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"When the Right Ventricle Becomes the Teacher: Lessons From Acute Right Heart Failure","authors":"ALEXANDRA MIHAI MD","doi":"10.1016/j.cardfail.2026.07.013","DOIUrl":"10.1016/j.cardfail.2026.07.013","url":null,"abstract":"","PeriodicalId":15204,"journal":{"name":"Journal of Cardiac Failure","volume":"32 10","pages":"Pages 1853-1855"},"PeriodicalIF":9.9,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148603360","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Advancements and Challenges in Acute Heart Failure Management in Korea: Initial Report and Insights from the Korean Heart Failure III Registry","authors":"HUIJIN LEE MD, Early Career,&nbsp;EUNG JU KIM MD, PhD,&nbsp;SEONG WOO HAN MD, PhD,&nbsp;SEONG-MI PARK MD, PhD,&nbsp;HYUNG-SEOP KIM MD, PhD,&nbsp;MYUNG-CHAN CHO MD, PhD,&nbsp;HYO-SUK AHN MD, PhD,&nbsp;Mi-SEUNG SHIN MD, PhD,&nbsp;SEOK-JAE HWANG MD, PhD,&nbsp;JIN-OK JEONG MD, PhD,&nbsp;DONG HEON YANG MD, PhD,&nbsp;JUNHO HYUN MD, PhD,&nbsp;JIN OH CHOI MD, PhD,&nbsp;HAE-YOUNG LEE MD, PhD,&nbsp;BYUNG-SU YOO MD, PhD,&nbsp;SEOK-MIN KANG MD, PhD,&nbsp;DONG-JU CHOI MD, PhD,&nbsp;HYUN-JAI CHO MD, PhD,&nbsp;KorHF III investigators","doi":"10.1016/j.cardfail.2025.07.023","DOIUrl":"10.1016/j.cardfail.2025.07.023","url":null,"abstract":"<div><h3>Background</h3><div>Heart failure (HF) is a major global health burden. Building on 2 previous national registries, the Korean Heart Failure III (KorHF III) registry provides a contemporary evaluation of clinical characteristics, treatment patterns, and outcomes in patients hospitalized with acute HF (AHF) in Korea.</div></div><div><h3>Methods and Results</h3><div>KorHF III prospectively enrolled 7351 patients with AHF from 47 tertiary hospitals between March 2018 and December 2022, with a 2-year follow-up. HF with reduced ejection fraction accounted for 57.3% of all cases. Common comorbidities included hypertension (59.5%) and diabetes (40.0%). The most frequent etiologies were ischemic heart disease (27.7%) and dilated cardiomyopathy (24.9%). At discharge, 74.3% of patients received angiotensin-converting enzyme inhibitors, angiotensin receptor blockers, or angiotensin receptor–neprilysin inhibitors; 68.5% received beta-blockers; and 57.4% received mineralocorticoid receptor antagonists. Prescriptions of sodium-glucose cotransporter 2 inhibitor were 15.8%. In-hospital mortality was 2.2%, and 2-year mortality was 20.9%, greatest among patients with HF with preserved ejection fraction (24.6%). Hyponatremia was independently associated with in-hospital (hazard ratio 2.50, <em>P</em> &lt; .001) and postdischarge mortality (HR 1.72, <em>P</em> &lt; .001).</div></div><div><h3>Conclusions</h3><div>KorHF III provides the most comprehensive and current assessment of AHF in Korea. Despite high prescription rates of guideline-directed medical therapy and low in-hospital mortality, long-term mortality is substantial. These findings emphasize the need for improved postdischarge care and highlight hyponatremia as a key prognostic factor in AHF management.</div></div>","PeriodicalId":15204,"journal":{"name":"Journal of Cardiac Failure","volume":"32 10","pages":"Pages 1754-1766"},"PeriodicalIF":9.9,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144955416","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lessons Learned from the HVAD Post-Approval Study Registry: Implications for Investigating Future Ventricular Assist Device Technology","authors":"JENNIFER A. COWGER MD, MS,&nbsp;IGOR D. GREGORIC MD, MBA,&nbsp;LIVIU KLEIN MD,&nbsp;DUC THINH PHAM MD,&nbsp;MICHAEL S. KIERNAN MD, MS, MBA,&nbsp;KORY J. LAVINE MD, PhD,&nbsp;JONATHAN D. RICH MD,&nbsp;MANJULA G. ANANTHRAM MBBS,&nbsp;ASHWIN RAVICHANDRAN MD, MPH,&nbsp;ALEXIS E. SHAFII MD,&nbsp;WILLIAM HIESINGER MD,&nbsp;BRENT C. LAMPERT DO,&nbsp;MANDAR A. ARAS MD, PhD,&nbsp;CLAUDIUS MAHR DO,&nbsp;JEFFREY J. TEUTEBERG MD,&nbsp;NADER MOAZAMI MD,&nbsp;Destination Therapy Post-Approval Study Investigators","doi":"10.1016/j.cardfail.2026.01.022","DOIUrl":"10.1016/j.cardfail.2026.01.022","url":null,"abstract":"","PeriodicalId":15204,"journal":{"name":"Journal of Cardiac Failure","volume":"32 10","pages":"Pages 1821-1825"},"PeriodicalIF":9.9,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147463357","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Heart Failure Devices: Treatment Options, Underutilization, and a Proposed Trigger System for Patient Referral and Evaluation","authors":"MARAT FUDIM MD, MHS,&nbsp;DMITRY M. YARANOV MD,&nbsp;RICHA GUPTA MD,&nbsp;LAURIE LETARTE MD,&nbsp;SAMUEL F. SEARS PhD,&nbsp;BRIAN G. HOWARD MD,&nbsp;NIR URIEL MD,&nbsp;VIKRAM RAJE DO,&nbsp;KIRAN MAHMOOD MD,&nbsp;SEAN P. PINNEY MD,&nbsp;AMIN YEHYA MD, MS,&nbsp;AMIT ALAM MD,&nbsp;PUJAN PATEL MD,&nbsp;ALBERT HICKS MD,&nbsp;AMARINDER BINDRA MD,&nbsp;STEVE M. ANTOINE MD,&nbsp;JASON FELIBERTI MD,&nbsp;ALLMAN ROLLINS MD,&nbsp;VISHAL N. RAO MD, MPH,&nbsp;PATRICK MCCANN MD,&nbsp;AHMED SAYED MD","doi":"10.1016/j.cardfail.2025.08.019","DOIUrl":"10.1016/j.cardfail.2025.08.019","url":null,"abstract":"<div><div>The use of guideline-directed medical therapy (GDMT) has substantially prolonged and improved the lives of patients with heart failure (HF). Nevertheless, adherence rates remain suboptimal. Even when successfully maximized and adhered to, there is a substantial residual risk of recurrent HF hospitalization and death. In light of this, there is a strong need for effective interventions that can decrease the high residual risk seen in patients with HF. Several device options exist that are approved by the US Food and Drug Administration and that have been shown to decrease morbidity and/or mortality in patients among whom GDMT is maximized. These strategies include valvular interventions (aortic valve replacement, mitral valve repair, and tricuspid valve repair or replacement), cardiac resynchronization, cardiac contractility modulation, remote hemodynamic monitoring, and baroreceptor activation therapy. The pivotal trials for each of these interventions, and the patient populations for which they have been approved, are discussed. Current rates of device use in clinical practice remain very low. For many device classes, the vast majority of eligible patients are not offered or prescribed the device. Several reasons may explain this mismatch, foremost of which is a lack of clinical awareness about when to escalate therapy, how to identify patients requiring more than GDMT, and access to centers with sufficient experience. To aid the appropriate uptake of device therapy in clinical practice, we propose a simple mnemonic for use by clinicians that can prompt the early identification and prompt referral of patients with HF who likely merit consideration of additional device-based therapy in addition to GDMT.</div></div>","PeriodicalId":15204,"journal":{"name":"Journal of Cardiac Failure","volume":"32 10","pages":"Pages 1795-1806"},"PeriodicalIF":9.9,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145185855","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Residual Risk of Hyperkalemia Among Patients with Heart Failure Treated with Both SGLT2i and ARNI","authors":"STEPHEN J. GREENE MD,&nbsp;SHACHI PATEL PhD,&nbsp;KHAJA CHINNAKONDEPALLI PhD,&nbsp;STEFAN D. ANKER MD, PhD,&nbsp;MICHAEL BÖHM MD,&nbsp;BIYKEM BOZKURT MD, PhD,&nbsp;JAVED BUTLER MD, MPH, MBA,&nbsp;JOHN GF. CLELAND MD, PhD,&nbsp;ANDREW J. COATS MD,&nbsp;NIHAR DESAI MD, MPH,&nbsp;VICTORIA DONACHIE MSc,&nbsp;ELLIE KELEPOURIS MD,&nbsp;GIUSEPPE ROSANO MD, PhD,&nbsp;CARLA-MARIA BRANDES PhD,&nbsp;ANDREW J. SAUER MD","doi":"10.1016/j.cardfail.2026.03.018","DOIUrl":"10.1016/j.cardfail.2026.03.018","url":null,"abstract":"","PeriodicalId":15204,"journal":{"name":"Journal of Cardiac Failure","volume":"32 10","pages":"Pages 1838-1841"},"PeriodicalIF":9.9,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147529197","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"“Readiness for Discharge” as a Novel Endpoint in Heart Failure Trials","authors":"MUHAMMAD SHAHZEB KHAN MD, MSc,,&nbsp;AHMED MUSTAFA RASHID MBBS,&nbsp;SEAN P. COLLINS MD, MSc,&nbsp;MARK C PETRIE MD,&nbsp;JEFFREY TESTANI MD,&nbsp;JAVED BUTLER MD, MPH, MBA","doi":"10.1016/j.cardfail.2026.01.008","DOIUrl":"10.1016/j.cardfail.2026.01.008","url":null,"abstract":"","PeriodicalId":15204,"journal":{"name":"Journal of Cardiac Failure","volume":"32 10","pages":"Pages 1845-1848"},"PeriodicalIF":9.9,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146052251","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Atrial Fibrillation and Heart Failure with Preserved Ejection Fraction: One Step Closer to Therapeutic Targets?","authors":"MANOJ S. AMBALAVANAN MD,&nbsp;NICOLE C. SCHULTE MS, PA-C,&nbsp;VISHAL N. RAO MD, MPH","doi":"10.1016/j.cardfail.2026.03.032","DOIUrl":"10.1016/j.cardfail.2026.03.032","url":null,"abstract":"","PeriodicalId":15204,"journal":{"name":"Journal of Cardiac Failure","volume":"32 10","pages":"Pages 1727-1729"},"PeriodicalIF":9.9,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147838299","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evolution of a Medical Career: Intersections and Adaptation","authors":"Randall C. Starling MD, MPH, FACC, FAHA, FHFSA, FESC, FRCP (London)","doi":"10.1016/j.cardfail.2026.09.002","DOIUrl":"10.1016/j.cardfail.2026.09.002","url":null,"abstract":"","PeriodicalId":15204,"journal":{"name":"Journal of Cardiac Failure","volume":"32 10","pages":"Pages 1687-1688"},"PeriodicalIF":9.9,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149175069","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Heart Failure Hospitalization in Randomized Trials of Tricuspid Valve Transcatheter Edge-to-Edge Repair: A Harmonized Estimand Analysis of Reconstructed Time-to-Event Data.","authors":"Aref A Bin Abdulhak, Mirvat Alasnag, Poghni Peri-Okonny","doi":"10.1016/j.cardfail.2026.09.035","DOIUrl":"https://doi.org/10.1016/j.cardfail.2026.09.035","url":null,"abstract":"","PeriodicalId":15204,"journal":{"name":"Journal of Cardiac Failure","volume":" ","pages":""},"PeriodicalIF":9.9,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149110099","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}