Journal of Cardiac Failure最新文献

{"title":"Celebrate 30 Years of HFSA at ASM 2025 – Reunite, Reflect, and Reimagine the Future of Heart Failure","authors":"","doi":"10.1016/j.cardfail.2025.08.001","DOIUrl":"10.1016/j.cardfail.2025.08.001","url":null,"abstract":"","PeriodicalId":15204,"journal":{"name":"Journal of Cardiac Failure","volume":"31 9","pages":"Pages 1493-1495"},"PeriodicalIF":8.2,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145020932","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"2023 Update of the Japanese Heart Failure Society Scientific Statement on BNP and NT-proBNP Levels in Heart Failure Practice","authors":"MASATOSHI MINAMISAWA MD, PhD ,&nbsp;TOSHIHISA ANZAI MD, PhD ,&nbsp;TAKAYUKI INOMATA MD, PhD ,&nbsp;KOICHIRO KINUGAWA MD, PhD ,&nbsp;YASUSHI SAKATA MD, PhD ,&nbsp;NAOKI SATO MD, PhD ,&nbsp;HIROYUKI TSUTSUI MD, PhD ,&nbsp;KAZUHIRO YAMAMOTO MD, PhD ,&nbsp;MICHIHIRO YOSHIMURA MD, PhD ,&nbsp;YOSHIHIKO SAITO MD, PhD ,&nbsp;KOICHIRO KUWAHARA MD, PhD","doi":"10.1016/j.cardfail.2025.03.005","DOIUrl":"10.1016/j.cardfail.2025.03.005","url":null,"abstract":"<div><div>This revised 2023 statement on blood brain (B-type) natriuretic peptide (BNP) and N-terminal prohormone of brain (B-type) natriuretic peptide (NT-proBNP) represents an expert consensus that aims to enhance efficient referral from general practitioners or non-cardiovascular specialists, providing a comprehensive, up-to-date perspective on BNP and NT-proBNP in the diagnosis and management of heart failure, with a focus on the following two major modifications: (1) Changes regarding cutoff values for BNP and NT-proBNP (criteria for heart failure diagnosis and referral criteria to cardiovascular specialists); and (2) Content related to heart failure management using BNP and NT-proBNP (BNP-guided therapy).</div></div>","PeriodicalId":15204,"journal":{"name":"Journal of Cardiac Failure","volume":"31 9","pages":"Pages 1453-1459"},"PeriodicalIF":8.2,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143692232","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Recovery of Left Ventricular Ejection Fraction in Patients With Anthracycline-Induced Cardiomyopathy: A Contemporary Cohort Study","authors":"OSNAT ITZHAKI BEN ZADOK MD, MSc ,&nbsp;PANAGIOTIS SIMITSIS MD ,&nbsp;ANJU NOHRIA MD, MSc","doi":"10.1016/j.cardfail.2024.12.012","DOIUrl":"10.1016/j.cardfail.2024.12.012","url":null,"abstract":"<div><h3>Background</h3><div>Data on left ventricular ejection fraction (LVEF) recovery in patients with anthracycline-induced cardiomyopathy (AIC) are limited.</div></div><div><h3>Objectives</h3><div>To evaluate LVEF recovery rate, its predictors and its association with cardiovascular outcomes in a contemporary and diverse cohort with AIC.</div></div><div><h3>Methods</h3><div>This retrospective study analyzed patients diagnosed with AIC from 2010–2023 at 2 U.S. university hospitals and an affiliated cancer center. LVEF recovery, defined as ≥ 10% improvement in LVEF to a value ≥ 50% within 3 years of AIC detection, was assessed by using Cox proportional-hazards accounting for competing risks. The association between LVEF recovery and the composite of heart failure (HF) hospitalizations, mechanical circulatory support, heart transplantation, or cardiovascular death was assessed by using Cox regression analysis with LVEF recovery as a time-dependent factor.</div></div><div><h3>Results</h3><div>Among 167 patients with anthracycline-induced cardiomyopathy (AIC) (median age 67 [Q1, Q3: 53, 74] years, 53% female), the majority had lymphoma (55%) or breast cancer (23%). The median time from first anthracycline exposure to AIC detection was 631 (219, 3569) days, and the median LVEF was 38% (29%, 45%). At the detection of AIC, 69% had symptomatic HF. LVEF recovered in 38% (n = 63) at a median of 349 (137, 691) days from AIC detection. Age ≥ 60 years at anthracycline exposure, non-white race, diabetes mellitus, longer interval between anthracycline exposure and AIC detection, and LV dilation were associated with a lower likelihood of recovery, while statin use and AIC detection after 2022 were associated with a higher likelihood of recovery. LVEF recovery was not associated with cardiovascular outcomes.</div></div><div><h3>Conclusion</h3><div>In this contemporary and diverse AIC cohort, 38% achieved LVEF recovery. Routine screening for AIC and statin therapy may improve recovery rates.</div></div>","PeriodicalId":15204,"journal":{"name":"Journal of Cardiac Failure","volume":"31 9","pages":"Pages 1379-1389"},"PeriodicalIF":8.2,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143023624","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Recipe for Heart Failure? Time to Recognize the Inflammatory Diet as a Risk Factor for Heart Failure","authors":"ADITYA MEHTA MD ,&nbsp;ATSUSHI MIZUNO MD ,&nbsp;HOWARD EISEN MD","doi":"10.1016/j.cardfail.2025.07.002","DOIUrl":"10.1016/j.cardfail.2025.07.002","url":null,"abstract":"","PeriodicalId":15204,"journal":{"name":"Journal of Cardiac Failure","volume":"31 9","pages":"Pages 1450-1452"},"PeriodicalIF":8.2,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144707630","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Treatment With mTOR Inhibitors as Primary Immunosuppression After Combined Heart and Kidney Transplantation","authors":"HILMI ALNSASRA MD ,&nbsp;RABEA ASLEH MD, PhD, MHA ,&nbsp;FOUAD KHALIL MD ,&nbsp;ELIAS AKIKI MD ,&nbsp;ALEXANDROS BRIASOULIS MD, PhD ,&nbsp;PATRICK G. DEAN MD ,&nbsp;ANDREW J. BENTALL MD, MBChB ,&nbsp;SUDHIR S. KUSHWAHA MD","doi":"10.1016/j.cardfail.2024.10.451","DOIUrl":"10.1016/j.cardfail.2024.10.451","url":null,"abstract":"<div><h3>Introduction</h3><div>Sirolimus (SRL) mitigates cardiac allograft vasculopathy (CAV) progression and confers renal protection after heart transplantation (HT). However, its safety and efficacy in patients undergoing combined heart and kidney transplantation (HKT) are unclear. This study aimed to investigate the impact of conversion from calcineurin inhibitors (CNIs) to SRL on CAV progression, renal function, and outcomes in HKT compared with isolated HT.</div></div><div><h3>Methods</h3><div>A cohort of 302 patients who underwent either HT only (n = 262) or HKT (n = 40) was analyzed. CAV progression was assessed by measuring the delta (Δ) annual change in plaque volume (PV) and plaque index (PI) using coronary intravenous ultrasound (IVUS). Clinical adverse outcomes included all-cause death and CAV-associated events. Overall, 217 (72%) patients were converted from CNI to SRL as primary immunosuppression. HT recipients were more likely to be converted to SRL than HKT recipients (74% vs. 55%, <em>P</em> = .01).</div></div><div><h3>Results</h3><div>HKT was associated with higher Δ PV (<em>P</em> = .01) and a trend toward higher ΔPI (<em>P</em> = .06) than HT only, but this association was attenuated after adjustment to SRL conversion. HKT was associated with similar risk of death (HR, 0.98; 95% CI 0.39–2.5, <em>P</em> = 0.97) and CAV-related events (HR, 1.6; 95% CI 0.91–2.8, <em>P</em><span> = .10). Conversion to SRL was associated with decreased risk of death and CAV-related events in the overall cohort. This association was not modified by the type of organ transplantation and without a significant effect on estimated glomerular filtration rate or proteinuria.</span></div></div><div><h3>Conclusion</h3><div>Conversion to sirolimus as a primary immunosuppressant could be effective for either HT-only or HKT recipients.</div></div>","PeriodicalId":15204,"journal":{"name":"Journal of Cardiac Failure","volume":"31 9","pages":"Pages 1408-1416"},"PeriodicalIF":8.2,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142800926","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Equip, Engage, Empower: Considerations for Effective Values Elicitation in the Population With LVAD","authors":"REBECCA S. STEINBERG MD, MSc ,&nbsp;RASHONDA A. CARLISLE MD ,&nbsp;CATHERINE SHELTON RN ,&nbsp;SHELLEY A. HALL MD ,&nbsp;ADITI NAYAK MD, MS","doi":"10.1016/j.cardfail.2025.06.007","DOIUrl":"10.1016/j.cardfail.2025.06.007","url":null,"abstract":"","PeriodicalId":15204,"journal":{"name":"Journal of Cardiac Failure","volume":"31 9","pages":"Pages 1405-1407"},"PeriodicalIF":8.2,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144567478","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Knowledge of Illness Trajectory and Symptoms of Heart Failure in Patients with Acute Coronary Syndrome","authors":"MOMOKO MASUDA PT ,&nbsp;KAZUKI TOBITA PT ,&nbsp;AYUMI GODA MD ,&nbsp;DAISUKE FUJISAWA MD ,&nbsp;SHINSUKE TAKEUCHI MD ,&nbsp;KOHEI KOYAMA MD ,&nbsp;SYOICHI TASHIRO MD ,&nbsp;SHIN YAMADA MD ,&nbsp;KYOKO SOEJIMA MD ,&nbsp;TAKASHI KOHNO MD","doi":"10.1016/j.cardfail.2024.11.013","DOIUrl":"10.1016/j.cardfail.2024.11.013","url":null,"abstract":"<div><h3>Background</h3><div>Preventive management of heart failure (HF) should involve strategies to increase awareness of HF in patients with pre-HF and those at risk of HF. However, the perception of HF in patients with acute coronary syndrome<span> (ACS) remains unclear. This study aimed to assess patient understanding of the definition of HF for the public—that is, its illness trajectory (intermittent decline), impact on life expectancy (HF would limit life expectancy), and symptoms (shortness of breath, swelling)—that was introduced by the Japanese Circulation Society.</span></div></div><div><h3>Methods</h3><div>This cross-sectional, questionnaire-based study enrolled 209 emergently admitted patients with ACS who underwent a cardiac rehabilitation program at a single university-based hospital. We identified the clinical characteristics of patients who understood HF definition.</div></div><div><h3>Results</h3><div>Among the enrolled patients (median age, 69 years; males, 81.3%; 59.8% with ST-elevation myocardial infarction), 64.0% and 53.1% chose the correct answers regarding HF illness trajectory and impact on life expectancy, respectively. While 92.3% of the patients correctly chose shortness of breath as an HF symptom, 56.7% correctly chose swelling. Patient understanding of the definition of HF was associated with younger age, but not with HF risk (i.e., hypertension, diabetes, higher natriuretic peptide levels, lower left ventricular ejection fraction) and history of symptomatic HF.</div></div><div><h3>Conclusions</h3><div>Among patients with ACS who participated in the cardiac rehabilitation program in this cohort, patient understanding of HF definition was suboptimal. Effective measures to improve their understanding should be considered to enhance the prevention of HF.</div></div>","PeriodicalId":15204,"journal":{"name":"Journal of Cardiac Failure","volume":"31 9","pages":"Pages 1430-1439"},"PeriodicalIF":8.2,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142836503","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Value of Community in Heart Failure","authors":"Anuradha Lala MD ,&nbsp;Robert J. Mentz MD","doi":"10.1016/j.cardfail.2025.08.003","DOIUrl":"10.1016/j.cardfail.2025.08.003","url":null,"abstract":"","PeriodicalId":15204,"journal":{"name":"Journal of Cardiac Failure","volume":"31 9","pages":"Pages 1377-1378"},"PeriodicalIF":8.2,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145020931","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An Evaluation of the Heart Failure Somatic Perception Scale Using Item Response Theory","authors":"QUIN E. DENFELD PhD, RN, FAHA, FAAN, FHFSA ,&nbsp;CORRINE Y. JURGENS PhD, RN, FAHA, FAAN, FHFSA ,&nbsp;SHIRIN O. HIATT MPh, MS, RN ,&nbsp;NATHAN F. DIECKMANN PhD ,&nbsp;MARY ROBERTS DAVIS PhD, RN ,&nbsp;S. ALBERT CAMACHO MD ,&nbsp;CHRISTOPHER V. CHIEN MD, FACC ,&nbsp;CHRISTOPHER S. LEE PhD, RN, FAHA, FAAN, FHFSA","doi":"10.1016/j.cardfail.2025.04.011","DOIUrl":"10.1016/j.cardfail.2025.04.011","url":null,"abstract":"","PeriodicalId":15204,"journal":{"name":"Journal of Cardiac Failure","volume":"31 9","pages":"Pages 1486-1489"},"PeriodicalIF":8.2,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144018793","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dietary Inflammatory Score and Incident Heart Failure in the Reasons for Geographic and Racial Differences in Stroke (REGARDS) Study","authors":"CHRISTINE M. PARK MD ,&nbsp;LAUREN BALKAN MD ,&nbsp;JOANNA B. RINGEL MPH ,&nbsp;JAMES SHIKANY PhD ,&nbsp;ROBIN BOSTICK MD, MPH ,&nbsp;SUZANNE E. JUDD MD ,&nbsp;CHANEL JONAS MD ,&nbsp;PANKAJ ARORA MD ,&nbsp;TODD M. BROWN MD, MSPH ,&nbsp;RAEGAN DURANT MD, MPH ,&nbsp;SCOTT HUMMEL MD, MS ,&nbsp;ELIZABETH A. JACKSON MD ,&nbsp;MADELINE R. STERLING MD, MPH ,&nbsp;RYAN DEMMER PhD, MPH ,&nbsp;MELANA YUZEFPOLSKAYA MD ,&nbsp;EMILY B. LEVITAN ScD. ,&nbsp;MONIKA M. SAFFORD MD ,&nbsp;PARAG GOYAL MD, MSc","doi":"10.1016/j.cardfail.2024.12.009","DOIUrl":"10.1016/j.cardfail.2024.12.009","url":null,"abstract":"<div><h3>Background</h3><div>Inflammation plays a key role in the development of heart failure (HF), and diet is a known modifiable factor that modulates systemic inflammation. The dietary inflammatory score (DIS) is a tool that quantifies the inflammatory components of diet. We sought to determine whether the DIS is associated with incident HF events.</div></div><div><h3>Methods</h3><div><span>We examined a total of 17,975 participants without HF at baseline who were in the REasons for Geographic and Racial Differences in Stroke (REGARDS) cohort. The main exposure variable was the DIS quartile, which was derived from the Food Frequency Questionnaire<span> obtained at baseline study enrollment. The main outcome was an incident HF event, defined as hospitalization due to HF or death. To examine the association between the DIS and incident HF events, we conducted Cox proportional hazard regression modeling, adjusting for total </span></span>energy intake, sociodemographic factors and pro-inflammatory lifestyle behaviors.</div></div><div><h3>Results</h3><div><span>The sample mean age was 64 + 9.2 years, 55.8% were female, and 32.3% were Black. Over a median follow-up of 11.1 years, we observed 900 incident HF events, including 752 hospitalizations and 148 deaths due to HF. In an adjusted model, the highest DIS quartile (Q4) was associated with incident HF (HR 1.26 95% CI 1.03–1.54). Of note, these findings remained, even after adjusting for comorbid conditions and physiological parameters. In an age-stratified analysis, the association was present only in those aged &lt; 65 years (Q4: HR 1.65 95% CI 1.08–2.51). Moreover, the association was present for heart failure with reserved ejection fraction (Q4: HR 1.44 95% CI 1.07–1.94) but not for </span>heart failure with preserved ejection fraction.</div></div><div><h3>Conclusion</h3><div>The highest DIS quartile was associated with incident HF events. These findings indicate the potential value of specific dietary patterns to prevent HF.</div></div>","PeriodicalId":15204,"journal":{"name":"Journal of Cardiac Failure","volume":"31 9","pages":"Pages 1440-1449"},"PeriodicalIF":8.2,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143005801","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}