{"title":"Keeping Score of Heart Failure Guideline-directed Medical Therapy","authors":"ADAM D. DeVORE MD, MHS , GREGG C. FONAROW MD","doi":"10.1016/j.cardfail.2024.09.006","DOIUrl":"10.1016/j.cardfail.2024.09.006","url":null,"abstract":"","PeriodicalId":15204,"journal":{"name":"Journal of Cardiac Failure","volume":"30 11","pages":"Pages 1421-1422"},"PeriodicalIF":6.7,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142307844","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
NIHARIKA NEELA MD , NICHOLAS S. HENDREN MD , SPENCER CARTER MD , LILIBETH HERNANDEZ PharmD , LAUREN K. TRUBY MD, MS , MARYJANE FARR MD , SANDEEP R. DAS MD
{"title":"Contraception Counseling and Teratogenic Prescriptions Among Women With Systolic Heart Failure in a Safety-Net Health System","authors":"NIHARIKA NEELA MD , NICHOLAS S. HENDREN MD , SPENCER CARTER MD , LILIBETH HERNANDEZ PharmD , LAUREN K. TRUBY MD, MS , MARYJANE FARR MD , SANDEEP R. DAS MD","doi":"10.1016/j.cardfail.2024.08.058","DOIUrl":"10.1016/j.cardfail.2024.08.058","url":null,"abstract":"","PeriodicalId":15204,"journal":{"name":"Journal of Cardiac Failure","volume":"30 11","pages":"Pages 1527-1529"},"PeriodicalIF":6.7,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142347281","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Spotlight on Devices in Heart Failure","authors":"Robert J. Mentz MD , Anuradha Lala MD","doi":"10.1016/j.cardfail.2024.10.434","DOIUrl":"10.1016/j.cardfail.2024.10.434","url":null,"abstract":"","PeriodicalId":15204,"journal":{"name":"Journal of Cardiac Failure","volume":"30 11","pages":"Pages 1401-1402"},"PeriodicalIF":6.7,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142621197","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
SATOSHI SHOJI MD, PhD , LISA A. KALTENBACH MS , BRADI B. GRANGER PhD, RN , GREGG C. FONAROW MD , HUSSEIN R. AL-KHALIDI PhD , NANCY M. ALBERT PhD, RN , JAVED BUTLER MD, MPH, MBA , LARRY A. ALLEN MD, MHS , G. MICHAEL FELKER MD, MHS , ROBERT W. HARRISON MD , MARAT FUDIM MD, MHS , ADAM J. NELSON MBBS, PhD , CHRISTOPHER B. GRANGER MD , ADRIAN F. HERNANDEZ MD, MHS , ADAM D. DEVORE MD, MHS
{"title":"Remote Follow-up in a Heart Failure Pragmatic Trial: Insights From the CONNECT-HF","authors":"SATOSHI SHOJI MD, PhD , LISA A. KALTENBACH MS , BRADI B. GRANGER PhD, RN , GREGG C. FONAROW MD , HUSSEIN R. AL-KHALIDI PhD , NANCY M. ALBERT PhD, RN , JAVED BUTLER MD, MPH, MBA , LARRY A. ALLEN MD, MHS , G. MICHAEL FELKER MD, MHS , ROBERT W. HARRISON MD , MARAT FUDIM MD, MHS , ADAM J. NELSON MBBS, PhD , CHRISTOPHER B. GRANGER MD , ADRIAN F. HERNANDEZ MD, MHS , ADAM D. DEVORE MD, MHS","doi":"10.1016/j.cardfail.2024.03.006","DOIUrl":"10.1016/j.cardfail.2024.03.006","url":null,"abstract":"<div><h3>Background</h3><div>Randomized controlled trials typically require study-specific visits, which can burden participants and sites. Remote follow-up, such as centralized call centers for participant-reported or site-reported, holds promise for reducing costs and enhancing the pragmatism of trials. In this secondary analysis of the CONNECT-HF (Care Optimization Through Patient and Hospital Engagement For HF) trial, we aimed to evaluate the completeness and validity of the remote follow-up process.</div></div><div><h3>Methods and Results</h3><div>The CONNECT-HF trial evaluated the effect of a post-discharge quality-improvement intervention for heart failure compared to usual care for up to 1 year. Suspected events were reported either by participants or by health care proxies through a centralized call center or by sites through medical-record queries. When potential hospitalization events were suspected, additional medical records were collected and adjudicated. Among 5942 potential hospitalizations, 18% were only participant-reported, 28% were reported by both participants and sites, and 50% were only site-reported. Concordance rates between the participant/site reports and adjudication for hospitalization were high: 87% participant-reported, 86% both, and 86% site-reported. Rates of adjudicated heart failure hospitalization events among adjudicated all-cause hospitalization were lower but also consistent: 45% participant-reported, 50% both, and 50% site-reported.</div></div><div><h3>Conclusions</h3><div>Participant-only and site-only reports missed a substantial number of hospitalization events. We observed similar concordance between participant/site reports and adjudication for hospitalizations. Combining participant-reported and site-reported outcomes data is important to capture and validate hospitalizations effectively in pragmatic heart failure trials.</div></div>","PeriodicalId":15204,"journal":{"name":"Journal of Cardiac Failure","volume":"30 11","pages":"Pages 1403-1410"},"PeriodicalIF":6.7,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140778007","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
IVAN NETUKA MD, PhD , ZUZANA TUCANOVA MD , MANDEEP R. MEHRA MD, MSc
{"title":"Direct Oral Anticoagulant Therapy With A Fully Magnetically Levitated LVAD and Bridging to Heart Transplantation: A DOT-HM3 Study Analysis","authors":"IVAN NETUKA MD, PhD , ZUZANA TUCANOVA MD , MANDEEP R. MEHRA MD, MSc","doi":"10.1016/j.cardfail.2024.05.005","DOIUrl":"10.1016/j.cardfail.2024.05.005","url":null,"abstract":"","PeriodicalId":15204,"journal":{"name":"Journal of Cardiac Failure","volume":"30 11","pages":"Pages 1512-1515"},"PeriodicalIF":6.7,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141199703","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sooyoon Shin PhD , Nathan Kowahl MS , Taylor Hansen PhD , Albee Y. Ling PhD , Poulami Barman MS , Nicholas Cauwenberghs PhD , Erin Rainaldi MS , Sarah Short MPH , Jessilyn Dunn PhD , Md Mobashir Hasan Shandhi PhD , Svati H. Shah MD, MHS , Kenneth W. Mahaffey MD , Tatiana Kuznetsova MD, PhD , Melissa A. Daubert MD , Pamela S. Douglas MD , Francois Haddad MD , Ritu Kapur PhD
{"title":"Real-world walking behaviors are associated with early-stage heart failure: a Project Baseline Health Study","authors":"Sooyoon Shin PhD , Nathan Kowahl MS , Taylor Hansen PhD , Albee Y. Ling PhD , Poulami Barman MS , Nicholas Cauwenberghs PhD , Erin Rainaldi MS , Sarah Short MPH , Jessilyn Dunn PhD , Md Mobashir Hasan Shandhi PhD , Svati H. Shah MD, MHS , Kenneth W. Mahaffey MD , Tatiana Kuznetsova MD, PhD , Melissa A. Daubert MD , Pamela S. Douglas MD , Francois Haddad MD , Ritu Kapur PhD","doi":"10.1016/j.cardfail.2024.02.028","DOIUrl":"10.1016/j.cardfail.2024.02.028","url":null,"abstract":"<div><h3>Background</h3><div>Data collected via wearables may complement in-clinic assessments to monitor subclinical heart failure (HF).</div></div><div><h3>Objectives</h3><div>Evaluate the association of sensor-based digital walking measures with HF stage and characterize their correlation with in-clinic measures of physical performance, cardiac function and participant reported outcomes (PROs) in individuals with early HF.</div></div><div><h3>Methods</h3><div>The analyzable cohort included participants from the Project Baseline Health Study (PBHS) with HF stage 0, A, or B, or adaptive remodeling phenotype (without risk factors but with mild echocardiographic change, termed RF-/ECHO+) (based on available first-visit in-clinic test and echocardiogram results) and with sufficient sensor data. We computed daily values per participant for 18 digital walking measures, comparing HF subgroups vs stage 0 using multinomial logistic regression and characterizing associations with in-clinic measures and PROs with Spearman's correlation coefficients, adjusting all analyses for confounders.</div></div><div><h3>Results</h3><div>In the analyzable cohort (N=1265; 50.6% of the PBHS cohort), one standard deviation decreases in 17/18 walking measures were associated with greater likelihood for stage-B HF (multivariable-adjusted odds ratios [ORs] vs stage 0 ranging from 1.18-2.10), or A (ORs vs stage 0, 1.07-1.45), and lower likelihood for RF-/ECHO+ (ORs vs stage 0, 0.80-0.93). Peak 30-minute pace demonstrated the strongest associations with stage B (OR vs stage 0=2.10; 95% CI:1.74-2.53) and A (OR vs stage 0=1.43; 95% CI:1.23-1.66). Decreases in 13/18 measures were associated with greater likelihood for stage-B HF vs stage A. Strength of correlation with physical performance tests, echocardiographic cardiac-remodeling and dysfunction indices and PROs was greatest in stage B, then A, and lowest for 0.</div></div><div><h3>Conclusions</h3><div>Digital measures of walking captured by wearable sensors could complement clinic-based testing to identify and monitor pre-symptomatic HF.</div></div>","PeriodicalId":15204,"journal":{"name":"Journal of Cardiac Failure","volume":"30 11","pages":"Pages 1423-1433"},"PeriodicalIF":6.7,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140573515","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}