Journal of Cardiac Failure最新文献

{"title":"Reconsidering the Clinical Integration of Lipoprotein(a) in Heart Failure Risk Models","authors":"XIA HE MM , YADI LI MD , XINMIN DENG MD","doi":"10.1016/j.cardfail.2025.04.009","DOIUrl":"10.1016/j.cardfail.2025.04.009","url":null,"abstract":"","PeriodicalId":15204,"journal":{"name":"Journal of Cardiac Failure","volume":"31 7","pages":"Pages 1096-1097"},"PeriodicalIF":6.7,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144132415","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Coronary Artery Calcium for Risk Stratification of Heart Failure Mortality: The Coronary Artery Calcium Consortium","authors":"OMAR MHAIMEED MD ,&nbsp;ZEINA A. DARDARI MS ,&nbsp;MICHAEL KHORSANDI MD ,&nbsp;OMAR DZAYE MD, MPH ,&nbsp;KAVITA SHARMA MD ,&nbsp;KHURRAM NASIR MD, MPH, MSc ,&nbsp;DANIEL S. BERMAN MD ,&nbsp;MATTHEW J. BUDOFF MD ,&nbsp;LESLEE J. SHAW PhD ,&nbsp;JOHN A. RUMBERGER MD, PhD ,&nbsp;MICHAEL D. MIEDEMA MD MPH ,&nbsp;MICHAEL J. BLAHA MD MPH","doi":"10.1016/j.cardfail.2024.10.437","DOIUrl":"10.1016/j.cardfail.2024.10.437","url":null,"abstract":"<div><h3>Background</h3><div>There is increasing interest in predicting heart failure (HF), a major cause of morbidity and mortality with a significant financial burden. The role of coronary artery calcium (CAC), an accessible and inexpensive test, in predicting long-term HF mortality among asymptomatic adults remains unknown. We aimed to determine whether CAC burden is associated with HF-related mortality in the CAC Consortium.</div></div><div><h3>Methods and Results</h3><div>The study included 66,636 primary prevention patients from the CAC Consortium. Multivariable competing risks regression was used to assess the association between CAC and HF-related mortality adjusting for demographics and traditional risk factors. The mean age was 54.4 years, 67% male, 89% White, and 55% had a CAC of &gt;0. We observed 260 HF-related mortality events during a median follow up of 12.5 years; 75.3% occurred among those with a baseline CAC score of &gt;100. Compared with a CAC of 0, there was a stepwise higher risk (<em>P</em> &lt; .005) of HF mortality for a CAC of 1–100 (subdistribution hazard ratio [SHR] 2.27, 95% CI 1.3–3.99), 100–400 (SHR 3.68, 95% CI 2.1–6.43), and &gt;400 (SHR 7.05, 95% CI 4.05–12.29). This increasing risk of HF mortality across higher CAC scores persisted across age groups, sex, and in the intermediate and high-risk groups as calculated by the pooled cohort equation and Predicting Risk of cardiovascular disease EVENTs (PREVENT) equation.</div></div><div><h3>Conclusions</h3><div>A higher CAC is associated with an increasing incidence of long-term HF-related mortality in the primary prevention population, particularly intermediate and high-risk patients. Early preventive approaches in patients with high CAC must focus on preventing HF and atherosclerotic cardiovascular disease with lifestyle changes and medications.</div></div>","PeriodicalId":15204,"journal":{"name":"Journal of Cardiac Failure","volume":"31 7","pages":"Pages 1005-1015"},"PeriodicalIF":6.7,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142639184","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Transcatheter Left Ventricular Restoration System: Ancora Heart Inc","authors":"YOGITA ROCHLANI MD,&nbsp;ENKLAJD MARSELA MD,&nbsp;ULRICH P. JORDE MD","doi":"10.1016/j.cardfail.2025.02.004","DOIUrl":"10.1016/j.cardfail.2025.02.004","url":null,"abstract":"","PeriodicalId":15204,"journal":{"name":"Journal of Cardiac Failure","volume":"31 7","pages":"Pages 1093-1095"},"PeriodicalIF":6.7,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143425466","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Role of Heart Failure Physicians in the Contemporary Cardiac Intensive Care Unit: Impact on Heart Failure as a Career Choice Among Fellowship Applicants","authors":"NIR URIEL MD, MSc ,&nbsp;JUSTIN FRIED MD ,&nbsp;ADIL YUNIS MD ,&nbsp;KEVIN CLERKIN MD ,&nbsp;DOR LOTAN MD ,&nbsp;BOAZ ELAD MD ,&nbsp;NANCY KELLY PA, MBA ,&nbsp;JAYANT RAIKHELKAR MD ,&nbsp;DANIEL BURKHOFF MD, PhD ,&nbsp;MARTIN LEON MD ,&nbsp;MANREET K. KANWAR MD ,&nbsp;GABRIEL T. SAYER MD","doi":"10.1016/j.cardfail.2025.02.006","DOIUrl":"10.1016/j.cardfail.2025.02.006","url":null,"abstract":"","PeriodicalId":15204,"journal":{"name":"Journal of Cardiac Failure","volume":"31 7","pages":"Pages 1062-1067"},"PeriodicalIF":6.7,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143425506","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cardiac Sarcoidosis: A Target of Rapamycin?","authors":"DANIEL SYKORA MD, MS, ,&nbsp;ANDREW ROSENBAUM MD","doi":"10.1016/j.cardfail.2025.05.012","DOIUrl":"10.1016/j.cardfail.2025.05.012","url":null,"abstract":"","PeriodicalId":15204,"journal":{"name":"Journal of Cardiac Failure","volume":"31 7","pages":"Pages 1037-1038"},"PeriodicalIF":6.7,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144142667","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Practice Variation in Thromboprophylaxis Management of Outpatient Pediatric Cardiomyopathy Patients: Survey of ACTION Providers","authors":"MADELEINE TOWNSEND MD ,&nbsp;MATTHEW J. O'CONNOR MD ,&nbsp;JOSEPH A. SPINNER MD ,&nbsp;SHAHNAWAZ AMDANI MD ,&nbsp;JENNIFER CONWAY MD","doi":"10.1016/j.cardfail.2025.02.017","DOIUrl":"10.1016/j.cardfail.2025.02.017","url":null,"abstract":"","PeriodicalId":15204,"journal":{"name":"Journal of Cardiac Failure","volume":"31 7","pages":"Pages 1090-1092"},"PeriodicalIF":6.7,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143673419","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reimagining Heart Failure Care: Highlights from ACC 2025","authors":"ALEXANDER G. HAJDUCZOK MD ,&nbsp;ELENA DONALD MD ,&nbsp;MERNA HUSSIEN MD ,&nbsp;MATTEO FABBRI MD ,&nbsp;DEVIN STIVES DO ,&nbsp;PATRICIA CAMPBELL MD ,&nbsp;ERSILIA M. DEFILIPPIS MD","doi":"10.1016/j.cardfail.2025.04.005","DOIUrl":"10.1016/j.cardfail.2025.04.005","url":null,"abstract":"","PeriodicalId":15204,"journal":{"name":"Journal of Cardiac Failure","volume":"31 7","pages":"Pages 1068-1071"},"PeriodicalIF":6.7,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144010870","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"HFpEF Without Obesity: Fallen Off the Radar?","authors":"ADAM J. NELSON MBBS, MPH, MBA, PhD ,&nbsp;NEHA J. PAGIDIPATI MD, MPH","doi":"10.1016/j.cardfail.2025.05.011","DOIUrl":"10.1016/j.cardfail.2025.05.011","url":null,"abstract":"","PeriodicalId":15204,"journal":{"name":"Journal of Cardiac Failure","volume":"31 7","pages":"Pages 1002-1004"},"PeriodicalIF":6.7,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144150357","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Utility of Mechanistic Target of Rapamycin Inhibitors in Cardiac Sarcoidosis","authors":"DONALD RICHARDS MD, MPH ,&nbsp;HIDESATO FUJITO MD, PhD ,&nbsp;AAKASH SHANBHAG ,&nbsp;BOBAK AKHAVAN MD ,&nbsp;ELIZABETH FRAME MD ,&nbsp;SEAN HAYES MD ,&nbsp;JOHN FRIEDMAN MD ,&nbsp;LOUISE THOMSON MD ,&nbsp;PIOTR SLOMKA PhD ,&nbsp;DANIEL BERMAN MD ,&nbsp;EVAN P. KRANSDORF MD, PhD","doi":"10.1016/j.cardfail.2024.10.444","DOIUrl":"10.1016/j.cardfail.2024.10.444","url":null,"abstract":"<div><h3>Background</h3><div>Cardiac sarcoidosis is an uncommon but potentially devastating manifestation of sarcoidosis, which is a multisystem inflammatory granulomatous disease. Although corticosteroids are the mainstay of treatment, given the number of complications associated with their long-term use, there is increasing interest in the use of steroid-sparing agents. Recent basic and translational studies have suggested a role for the mechanistic target of rapamycin (mTOR) pathway in cardiac sarcoidosis.</div></div><div><h3>Methods</h3><div>We identified 4 patients treated at the Cedars-Sinai Cardiac Sarcoidosis Clinic who had active cardiac sarcoidosis and contraindications to corticosteroid intensification. We sought to evaluate the role of mechanistic target of mTOR inhibitors on the change in cardiac inflammation via cardiac ¹⁸ F-fluorodeoxyglucose (FDG) positron emission tomography (PET) imaging.</div></div><div><h3>Results</h3><div>Of the 4 patients, 2 showed substantial improvement in cardiac inflammation on follow-up FDG-PET imaging after 6 months of treatment with an mTOR inhibitor but without corticosteroid intensification. There was a greater than 80% reduction in the cardiometabolic activity. The other 2 patients treated with an mTOR inhibitor had persistent evidence of cardiac inflammation on follow-up FDG-PET, necessitating an augmented treatment regimen.</div></div><div><h3>Discussion</h3><div>This case series represents the first clinical use of mTOR inhibitors for cardiac sarcoidosis, and it suggests that these agents may have a role in the management of cardiac sarcoidosis.</div></div>","PeriodicalId":15204,"journal":{"name":"Journal of Cardiac Failure","volume":"31 7","pages":"Pages 1032-1036"},"PeriodicalIF":6.7,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142769292","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sleeping on Pins and Needles: Exploring the Decline in Sleep Quality for Close Family Members of Cardiac-Arrest Survivors and How to Intervene","authors":"SARAH M. PERMAN MD, MSCE ,&nbsp;ALEXANDER M. PRESCIUTTI PhD","doi":"10.1016/j.cardfail.2025.04.012","DOIUrl":"10.1016/j.cardfail.2025.04.012","url":null,"abstract":"","PeriodicalId":15204,"journal":{"name":"Journal of Cardiac Failure","volume":"31 7","pages":"Pages 1030-1031"},"PeriodicalIF":6.7,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144150359","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}