Natalie S Dorsey, Alec E Biscopink, Brian A Houston, Jessica Atkins, Arman Kilic, Mathew Gregoski, Ryan J Tedford, Jan M Griffin
{"title":"Amiodarone Association With Severe Primary Graft Dysfunction and Vasoactive Inotropic Score After Heart Transplantation.","authors":"Natalie S Dorsey, Alec E Biscopink, Brian A Houston, Jessica Atkins, Arman Kilic, Mathew Gregoski, Ryan J Tedford, Jan M Griffin","doi":"10.1016/j.cardfail.2025.05.015","DOIUrl":"10.1016/j.cardfail.2025.05.015","url":null,"abstract":"<p><strong>Background: </strong>The impact of amiodarone on severe primary graft dysfunction (PGD) and vasoactive inotropic scores (VISs) following heart transplantation (HT) is unclear.</p><p><strong>Methods and results: </strong>We investigated these relationships through a retrospective study of 183 consecutive patients >18 years old who underwent isolated HT at our center from 2018-2023. Data for amiodarone use in the 6 months pre-HT were recorded (duration, cumulative dosage, use at HT, last dose pre-HT). Of the 69 patients in the amiodarone cohort, 37 were considered to be taking amiodarone at the time of transplant. The primary endpoint was severe PGD, as defined by the International Society of Heart and Lung Transplantation (ISHLT) criteria. Post-HT VISs were calculated as defined by ISHLT.</p><p><strong>Conclusions: </strong>Amiodarone was not associated with severe PGD (P = 0.67), and there was no difference in post-transplant VISs based on amiodarone exposure [20 (19.6) vs 16.3 (13.8); P = 0.122] (Fig. 1). This study supports similar hemodynamic profiles post-HT, regardless of amiodarone use.</p>","PeriodicalId":15204,"journal":{"name":"Journal of Cardiac Failure","volume":" ","pages":""},"PeriodicalIF":6.7,"publicationDate":"2025-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144484511","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Back to Basics: Self-Care Education to Empower Patients With Heart Failure.","authors":"Colleen K McIlvennan, Jill Howie-Esquivel","doi":"10.1016/j.cardfail.2025.06.001","DOIUrl":"10.1016/j.cardfail.2025.06.001","url":null,"abstract":"","PeriodicalId":15204,"journal":{"name":"Journal of Cardiac Failure","volume":" ","pages":""},"PeriodicalIF":6.7,"publicationDate":"2025-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144325876","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Gloria H W Lau, Tung Wai Auyeung, Emer Joyce, Julee McDonagh, Ka Man Yu, Jean Woo, Jenny S W Lee, Sunita Jha, Peter S Macdonald, Erik Fung
{"title":"Consolidating Concepts From Recent International Expert Consensus on Sarcopenia: Implications for Heart Failure Management.","authors":"Gloria H W Lau, Tung Wai Auyeung, Emer Joyce, Julee McDonagh, Ka Man Yu, Jean Woo, Jenny S W Lee, Sunita Jha, Peter S Macdonald, Erik Fung","doi":"10.1016/j.cardfail.2025.03.021","DOIUrl":"10.1016/j.cardfail.2025.03.021","url":null,"abstract":"<p><p>Heart failure (HF) is a clinical syndrome associated with a range of pathophysiological disorders, including secondary sarcopenia that reduces patients' quality of life, mobility, physical fitness, and capacity to undergo rehabilitation and recovery from acute decompensation. Although international expert writing groups have convened and developed consensus documents for sarcopenia, the vast majority of the content has focused on the disorder from the aging perspective. HF is rarely or never considered in the available consensus statements and recommendations. Moreover, there are differences in the sarcopenia diagnostic criteria pertaining to race/ethnicity (translating into differences in body composition and anthropometry), investigative methodologies, practice patterns, and variations in access to health care resources across nations that are not discussed in the current HF-management guidelines. Here, we review the key contents of the recent major international consensus documents concerning sarcopenia that were published between 2019 and 2024. We highlight the gaps in knowledge (eg, sarcopenic obesity, cardiac atrophy/wasting) and recent developments in HF treatment (eg sodium glucose co-transporter 2 inhibitors) and interventions (eg, rehabilitation, inspiratory muscle training) that may benefit sarcopenia; and we reformulate the 4-step pathway of early screening, investigation, diagnosis and severity determination (Find-Assess-Confirm-Severity) for sarcopenia as a vital part of HF management under a multidisciplinary care team.</p>","PeriodicalId":15204,"journal":{"name":"Journal of Cardiac Failure","volume":" ","pages":""},"PeriodicalIF":6.7,"publicationDate":"2025-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144325877","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Improving ATTR-CM Detection: Targeting Populations With the Greatest Need.","authors":"Joban Vaishnav, Kevin M Alexander","doi":"10.1016/j.cardfail.2025.04.017","DOIUrl":"10.1016/j.cardfail.2025.04.017","url":null,"abstract":"","PeriodicalId":15204,"journal":{"name":"Journal of Cardiac Failure","volume":" ","pages":""},"PeriodicalIF":6.7,"publicationDate":"2025-06-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144309960","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nicola Melarkey, Jozine M Ter Maaten, Patricia Campbell, Niels Grote Beverborg
{"title":"JCF in Case you Missed it! ESC Heart Failure Congress 2025.","authors":"Nicola Melarkey, Jozine M Ter Maaten, Patricia Campbell, Niels Grote Beverborg","doi":"10.1016/j.cardfail.2025.05.014","DOIUrl":"10.1016/j.cardfail.2025.05.014","url":null,"abstract":"","PeriodicalId":15204,"journal":{"name":"Journal of Cardiac Failure","volume":" ","pages":""},"PeriodicalIF":6.7,"publicationDate":"2025-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144274957","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Differential Prognostic Impact of Clinical Congestion between Preserved versus Reduced Ejection Fraction in Patients Hospitalized for Acute Decompensated Heart Failure: Findings from the Japanese Kyoto Congestive Heart Failure Registry","authors":"KAZUYA NAGAO MD , TAKAO KATO MD , HIDENORI YAKU MD , TAKESHI MORIMOTO MD, MPH , KENJI AIDA MD , SHIORI KAWAKAMI MARUICHI MD , YASUTAKA INUZUKA MD , YODO TAMAKI MD , ERIKA YAMAMOTO MD , YUSUKE YOSHIKAWA MD , TAKESHI KITAI MD , RYOJI TANIGUCHI MD , MORITAKE IGUCHI MD , MASASHI KATO MD , MAMORU TAKAHASHI MD , TOSHIKAZU JINNAI MD , TAKAFUMI KAWAI MD , AKIHIRO KOMASA MD , RYUSUKE NISHIKAWA MD , YUICHI KAWASE MD , TAKESHI KIMURA MD","doi":"10.1016/j.cardfail.2024.08.060","DOIUrl":"10.1016/j.cardfail.2024.08.060","url":null,"abstract":"<div><h3>Background</h3><div>Most patients hospitalized for heart failure (HF) present with signs of congestion. Prognostic significance of clinical congestion may vary depending on left ventricular ejection fraction (LVEF). This study aims to investigate the prognostic impact of congestion across different LVEF categories.</div></div><div><h3>Methods and Results</h3><div>Composite congestion scores (CCSs; 0–9) derived from the severity of edema, jugular venous pressure, and orthopnea, were analyzed on admission and at discharge in 3787 patients hospitalized for HF (LVEF ≥ 40%: n = 2347, LVEF < 40%: n = 1440). The median admission CCS was 4 in both LVEF strata (<em>P</em> = .64). Adjusted hazard ratios (HRs; 95% confidence interval [CI]) of the moderate (CCS 4–6) and severe congestion [7–9] groups relative to the mild congestion [0–3] group on admission for a composite of all-cause death or HF rehospitalization were 1.20 (1.04–1.39, <em>P</em> = .01) and 1.54 (1.27–1.86, <em>P</em> < .001) in the LVEF ≥ 40% stratum, and 1.20 (1.01–1.44, <em>P</em> = .04) and 0.82 (0.61–1.07, <em>P</em> = .14) in the LVEF < 40% stratum, respectively (<em>P</em><sub>interaction</sub>< .001). A total of 16% of the patients with LVEF ≥40% and 14% with LVEF <40% had residual congestion (CCS ≥ 1) at discharge, which was associated with a respective adjusted HR of 1.40 (1.18–1.65, <em>P</em> < .001) and 1.25 (0.98–1.58, <em>P</em> = .07) for postdischarge death or HF rehospitalization (<em>P</em><sub>interaction</sub> = 0.63).</div></div><div><h3>Conclusion</h3><div>The severity of clinical congestion on admission was associated with adverse clinical outcomes in patients with LVEF ≥ 40%, but not in those with LVEF < 40%. These findings warrant further studies to better understand the detailed profile of congestion across the LVEF spectrum.</div></div>","PeriodicalId":15204,"journal":{"name":"Journal of Cardiac Failure","volume":"31 6","pages":"Pages 912-924"},"PeriodicalIF":6.7,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142365361","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
NATHALIE MCINTOSH PhD , HAYLEY BILLINGSLEY PhD , SCOTT L. HUMMEL MD , WHITNEY L. MILLS PhD
{"title":"Medically Tailored Meals in Heart Failure: A Systematic Review of the Literature, 2013-2023","authors":"NATHALIE MCINTOSH PhD , HAYLEY BILLINGSLEY PhD , SCOTT L. HUMMEL MD , WHITNEY L. MILLS PhD","doi":"10.1016/j.cardfail.2024.10.446","DOIUrl":"10.1016/j.cardfail.2024.10.446","url":null,"abstract":"<div><h3>Background</h3><div>Dietary interventions have potential to improve symptoms and outcomes in patients with heart failure (HF), but there are barriers to eating nutrient-dense diets. One strategy to address challenges is to provide medically tailored meals (MTMs), fully prepared meals that align with an individual's nutritional needs. In this systematic review, we examined clinical outcomes of studies that provided MTMs to patients with HF.</div></div><div><h3>Methods and results</h3><div>We searched CINAH, EBSCO/MEDLINE, EMBASE, PUBMED and the Cochrane Central Register of Controlled Trials to identify MTM interventions published between 2013 and 2023. We included six studies. Five studies involved sodium restriction. Four of these were randomized control trials and one was a matched cohort study. Sample sizes ranged from 31 to 641. Patient populations included individuals who had heart failure, acute decompensated heart failure and heart failure with preserved ejection fraction. One study involved energy restriction in patients with heart failure with preserved ejection fraction and obesity. This was a randomized controlled study with a sample size of 100. Sodium-restriction interventions, when aligned with Dietary Approaches to Stop Hypertension goals, reduced 90-day HF readmissions in one study and trended towards improving 30-day and 12-week HF readmissions in another. The energy-restriction intervention reduced diastolic blood pressure, weight, and inflammatory biomarkers, and improved quality of life (QoL) and cardiorespiratory fitness. Neither intervention had an impact on mortality.</div></div><div><h3>Conclusions</h3><div>Provision of sodium-restricted MTMs to patients with HF may reduce the risk of rehospitalization. Provision of energy-restricted MTMs to patients with HF and obesity can improve symptoms, weight loss, QoL, and cardiorespiratory fitness. Adequately powered randomized controlled trials are needed to confirm these effects and investigate underlying mechanisms.</div></div>","PeriodicalId":15204,"journal":{"name":"Journal of Cardiac Failure","volume":"31 6","pages":"Pages 939-950"},"PeriodicalIF":6.7,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142824227","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
MICHAEL GAO MD , HANNAH EVERY MD , JEHANZEB KAYANI MD , ANURADHA LALA MD
{"title":"A Call to Focus on Prevention in Heart Failure: Heart Failure Risk Patterns and Profiles in the National Health and Nutrition Examination Survey Using PREVENT-HF","authors":"MICHAEL GAO MD , HANNAH EVERY MD , JEHANZEB KAYANI MD , ANURADHA LALA MD","doi":"10.1016/j.cardfail.2025.03.011","DOIUrl":"10.1016/j.cardfail.2025.03.011","url":null,"abstract":"","PeriodicalId":15204,"journal":{"name":"Journal of Cardiac Failure","volume":"31 6","pages":"Pages 976-978"},"PeriodicalIF":6.7,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143772519","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
FILIPPO CALÌ MD , ALBERTO PINSINO MD , ANNAMARIA LADANYI MD , GIULIO M. MONDELLINI MD , CHANGHEE LEE BS , GABRIEL T. SAYER MD , YUJI KAKU MD, PhD , NIR URIEL MD , KOJI TAKEDA MD, PhD , JUSTIN G. AARON MD , MELANA YUZEFPOLSKAYA MD , PAOLO C. COLOMBO MD
{"title":"Influence of Environmental Temperature on the Occurrence of Driveline Infection in Patients With LVADs","authors":"FILIPPO CALÌ MD , ALBERTO PINSINO MD , ANNAMARIA LADANYI MD , GIULIO M. MONDELLINI MD , CHANGHEE LEE BS , GABRIEL T. SAYER MD , YUJI KAKU MD, PhD , NIR URIEL MD , KOJI TAKEDA MD, PhD , JUSTIN G. AARON MD , MELANA YUZEFPOLSKAYA MD , PAOLO C. COLOMBO MD","doi":"10.1016/j.cardfail.2025.01.024","DOIUrl":"10.1016/j.cardfail.2025.01.024","url":null,"abstract":"","PeriodicalId":15204,"journal":{"name":"Journal of Cardiac Failure","volume":"31 6","pages":"Pages 972-975"},"PeriodicalIF":6.7,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143531511","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}