Medical Parasitology and Parasitic Diseases最新文献

{"title":"CHARACTERISTICS OF VARIABILITY OF PARASITIC SYSTEMS OF ECHINOCOCCOSIS AND MULTI-CHAMBER ECHINOCOCCOSIS FOR A LONG PERIOD IN THE KYRGYZ REPUBLIC","authors":"K. M. Raimkulov, M. Aliev, A. D. Adambekova, V. Toigombaeva, O. Kuttubaev","doi":"10.33092/0025-8326mp2022.1.11-19","DOIUrl":"https://doi.org/10.33092/0025-8326mp2022.1.11-19","url":null,"abstract":"Recently, the epidemic situation for echinococcosis in the Kyrgyz Republic (KR) is quite complicated. For the period from 1990 to 2019, according to the results of a retrospective analysis, in the Kyrgyz Republic – the highest prevalence of the population was recorded in 2014 and amounted to 20,20/0000. The lowest prevalence was in 1990 and the indicator was 5,20/0000. There is a tendency towards an increase in the incidence of echinococcosis of the entire population of the Kyrgyz Republic. The average annual growth rate was 3.5%. The mechanisms of cross-infection of a large biodiversity of intermediate hosts in agricultural and natural ecosystems are realized due to fertile strains of E. granulosus, and are mediated through a circle of definitive hosts. Echinococcosis is a complex parasitic system, the structural components of which are cestodes of the genus Echinococcus at different stages of development, as well as animals and humans, which are the hosts of various stages of the parasite’s life cycle. The population of parasites is an integrating link of the parasitic system formed by a specific population of the parasite and the populations of all hosts that support its existence. The parasitic system is based on the interaction between the populations of the parasite and the hosts, developed in the course of evolution. Key words: cystic echinococcosis, alveolar echinococcosis, parasitic system, characteristics of variability, focus, morbidity","PeriodicalId":152020,"journal":{"name":"Medical Parasitology and Parasitic Diseases","volume":"20 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132612584","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"PARASITIC DISEASES IN KYRGYZSTAN","authors":"Gulina Mambet kyzy, K. M. Raimkulov, J. Usubalieva, V. Toigombaeva","doi":"10.33092/0025-8326mp2022.1.20-30","DOIUrl":"https://doi.org/10.33092/0025-8326mp2022.1.20-30","url":null,"abstract":"The article presents data on parasitic infections prevalence among the population of the Kyrgyz Republic (KR) population. There are about 20 species of parasitic diseases in the country. Helminthiases have been increasing in recent years, inscidence range from 790 to 1000 per 100 thousand population, however, taking parasitic infections prevalence in account the correction factor, the true number of them can range from 350 to 500 thousand. The population according to the sanitary epidemiological surveillance (SES) varies from 36% to 72.8%. Children hold 80% of identified infected people.","PeriodicalId":152020,"journal":{"name":"Medical Parasitology and Parasitic Diseases","volume":"27 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130125356","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"MOLECULAR-GENETIC CHARACTERISTICS OF MICROPARASITOCENOSIS MEMBERS IN OPISTORCHIASIS","authors":"K. B. Stepanova, L. V. Kataeva, T. Stepanova, O. N. Kolotova","doi":"10.33092/0025-8326mp2022.1.3-10","DOIUrl":"https://doi.org/10.33092/0025-8326mp2022.1.3-10","url":null,"abstract":"For the first time, an attempt was made to study the genome of Escherichia coli and Klebsiella pneumoniae strains isolated from patients diagnosed with opisthorchiasis. It was shown that 9 out of 13 investigated E. coli strains isolated from patients with opisthorchiasis invasion belonged to diarrheogenic groups: ETEC – O6, O8, O25; EPEC – O18, EIEC – O144; ExPEC – O1, O2. Whole genome sequencing of K. pneumoniae strains revealed that among 13 cultures isolated from patients with opisthorchiasis, 8 were assigned to one serotype O1 (v1, v2), which amounted to 53.8%. Serotype O5 accounted for 23.1% of strains, and isolated serotypes O2 and O3 were identified, which were detected in 80% of cases of infections caused by K. pneumoniae. Opisthorchiasis invasion to a greater extent affects the colonization of the human body by strains of E. coli and K. pneumoniae, carriers of clusters of pathogenicity and virulence genes, which is possibly associated with impaired immunity, or a more pronounced effect of Opisthorchis felineus metabolites. Key words: opisthorchiasis, microparasitocenosis, whole genome sequencing, Escherichia coli, Klebsiella pneumoniae","PeriodicalId":152020,"journal":{"name":"Medical Parasitology and Parasitic Diseases","volume":"16 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132663016","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"FATAL RATES OF MALARIA PATIENTS IN THE RUSSIAN FEDERATION IN 2020","authors":"T. Stepanova, M. Belyaeva, K. B. Stepanova, A. Baranova, I.V. Trushnikova, N. S. Malysheva","doi":"10.33092/0025-8326mp2021.3.21-24","DOIUrl":"https://doi.org/10.33092/0025-8326mp2021.3.21-24","url":null,"abstract":"The article presents data on 7 deaths of patients with malaria (Plasmodium falciparum) in 2020 in the Russian Federation, errors in the epidemiological, clinical and laboratory diagnostics of malaria. The use of preventive measures and effective drugs, adherence to the Protocol for the treatment of patients with malaria of various types, improving the knowledge of medical personnel of medical and preventive medical organizations are especially necessary during a pandemic of a new coronavirus infection for the timely differential diagnosis of diseases. Key words: malaria, clinical diagnostics, treatment, deaths.","PeriodicalId":152020,"journal":{"name":"Medical Parasitology and Parasitic Diseases","volume":"17 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123378288","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A CASE OF BALANTIDIASIS IN HUMANS","authors":"N.J. Gurina, T. A. Semenova, G. Kostyuk","doi":"10.33092/0025-8326mp2021.3.59-63","DOIUrl":"https://doi.org/10.33092/0025-8326mp2021.3.59-63","url":null,"abstract":"The article describes a clinical case of balantidiasis, an invasive protozoal zoonotic disease that is relatively rarely diagnosed in humans. The development of invasion is accompanied by serious risks of penetration of the pathogen into the tissues, as a rule, an erosive and ulcerative process develops in the large intestine. The relevance of invasion remains in modern civilization both in terms of the clinic and treatment, and the epidemiology of balantidiasis. Key words: infusoria, balantidium, infusory dysentery, protozoosis, human parasitic disease.","PeriodicalId":152020,"journal":{"name":"Medical Parasitology and Parasitic Diseases","volume":"40 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133816731","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"THE ABUNDANCE OF BORRELIA INIXODID TICKS OF BAIKAL REGION","authors":"O. Mel’nikova, Yu N Trushina, R. V. Adel’shin, N. V. Yakovchits, E. Vershinin, Y. Verzhutskaya, E. I. Andaev","doi":"10.33092/0025-8326mp2021.3.12-20","DOIUrl":"https://doi.org/10.33092/0025-8326mp2021.3.12-20","url":null,"abstract":"Ixodid ticks (n=3714) from natural foci of Baikal Region (Irkutsk Region and Republic of Buryatia) have been examined for pathogenic Borrelia DNA during 2013-2010. On average 40.9 % of the samples were positive for Borrelia markers during the survey period; the range of variantion was – 32–55 %. The increasing of infection rate in ticks is traced in multi-year trends. During the ticks’ activity season, maximal infection rates have been noted at the end of the season (60 %), minimal – at the very beginning of the season (28,6 %) and on the peak of vectors’ abundance (36-39 %). The significant geographical, species and age differences have been detected in Borrelia infection rate of Ixodid ticks. Borrelia DNA have been detected considerably more often in taiga tick (the main vector of Ixodid tick borrelioses in Siberia) and in its nymphs more often, than in adult ticks. There was no difference in the infection rate of male and female ticks, and also between ticks, collected from the vegetation and from human and animals. The ratio og genotyped Borrelia species had been as follows: 64.2 % – B. garinii, 21,7 % – B. afzelii, 14,2 % – B. miyamotoi. Key words: Ixodid ticks, pathogenic Borrelia, PCR, genotyping, Baikal Region.","PeriodicalId":152020,"journal":{"name":"Medical Parasitology and Parasitic Diseases","volume":"202 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131828471","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"IS BLASTOCYST INVASION A COMORBID PATHOLOGY?","authors":"V. Shahinian, I. Filchakov, N. Kharchenko, O. Danko, H.V. Sopil, O.P. Diachenko, S.P. Yasenovy","doi":"10.33092/0025-8326mp2021.3.51-58","DOIUrl":"https://doi.org/10.33092/0025-8326mp2021.3.51-58","url":null,"abstract":"Blastocystis spp. - unicellular protozoa, widespread in the human population, the clinical significance of which is being discussed. The aim and objectives of the work: to study the prevalence of Blastocystis spp. in patients with gastrointestinal diseases and individuals with immunodeficiency states (HIV-positive patients), to determine the presence of specific gastrointestinal symptoms in blastocyst invasion (BI). Testing for Blastocystis spp. persons who have not been diagnosed with gastrointestinal tract disease (253) - comparison group (CG); patients who underwent inpatient or outpatient treatment for gastrointestinal diseases - GI-1 (182); people living with HIV (PLHIV) - GI-2 (294). With the consent of the patient, data on the duration of the illness and complaints were obtained. In IG-2 patients, the immune status, the level of HIV viral load, as well as the receipt and duration of antiretroviral therapy (ART) were determined. Detection rate of Blastocystis spp. in the CG was (22.9 ± 3.0)%; in GI-1 - (29.7 ± 4.0)%, in the PLHIV group - (14.3 ± 2.0)%. In the comparison group, invasion was more often detected in people 20-29 years old, in GI-1 - in people 50-60 years old, GI-2 - in 30-39 years old. Statistically significant differences in the detection of Blastocystis spp. those related to sex and age were absent in all groups. BI was most often found in patients with inflammatory bowel diseases - (43.5 ± 8.4)%. In patients with irritable bowel syndrome, the of frequency of detection of Blastocystis spp. practically did not differ from the average indicator in the GI. Identification of Blastocystis spp. in PLHIV was associated with immune status, the level of HIV viral load in the patient, and also receiving ART. The «risk group» was PLHIV with a CD4-lymphocyte count of less than 200 cells / μl, who did not receive ART. Comparison of the patient survey data and the results of the parasitological examination indicates the absence of specific complaints in BI. BI often is а comorbid pathology in inflammatory bowel diseases or immunosuppressive conditions, which should be taken into account in the therapy of such patients. Key words: blastocyst infection; gastrointestinal diseases; HIV infection.","PeriodicalId":152020,"journal":{"name":"Medical Parasitology and Parasitic Diseases","volume":"19 5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125614371","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"MODERN EPIDEMIOLOGICAL SITUATION ON PARASITIC DISEASES IN THE KYRGYZ REPUBLIC","authors":"Mambet kyzy Gulinа, K. M. Raimkulov, T. Isakov, V. Toigombaeva, O. Kuttubaev, N. S. Malysheva","doi":"10.33092/0025-8326mp2021.3.38-44","DOIUrl":"https://doi.org/10.33092/0025-8326mp2021.3.38-44","url":null,"abstract":"The analysis of the epidemiological situation on parasitic diseases for 2008-2019 showed an upward trend. The prevalence of intestinal infections is one of the most important indicators of social and sanitary wellbeing. According to the age category, children of preschool and school age are more susceptible to invasion. According to the gender distribution, there is a relatively high prevalence in women. During the analyzed period, the parasitic structure throughout the republic among the examined individuals was formed from eleven nosological forms that are more common in the country: enterobiosis, giardiasis, ascariasis, hymenolepidosis, teniarynchosis, teniosis, echinococcosis, alveococcosis, dicrocelesis, fasciolosis, trichocephalosis. During the analyzed period in the Kyrgyz Republic (KR), the average long-term incidence of parasitoses per 1000 examined persons was 34.5, the minimum - 32.6 (2008) and the maximum-38.4 (2012). Key words: invasion, mixed invasion, enterobiasis, ascariasis, echinococcosis, giardiasis, lesion, longterm indicator.","PeriodicalId":152020,"journal":{"name":"Medical Parasitology and Parasitic Diseases","volume":"20 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122370582","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"CHARACTERISTICS OF NATURAL TICK-BORNE ENCEPHALITIS FOCI IN THE TOMSK REGION","authors":"N. Poltoratskaya, T. N. Poltoratskaya, T. Pankina, M. V. Kondratyev, A. Shikhin, А.А. Rudikov","doi":"10.33092/0025-8326mp2021.3.3-11","DOIUrl":"https://doi.org/10.33092/0025-8326mp2021.3.3-11","url":null,"abstract":"This paper characterizes the current epidemiological situation of tick-borne encephalitis in the Tomsk region. There has been a decrease in the incidence of TBE for 10 years. There was made an attempt to typify the epidemiological situation of tick-borne encephalitis nidus on the basis of analysis of epidemiological data of the recent years (2011-2020) in the context of administrative territories of Tomsk region. The typification of the foci of TBE was carried out in the context of the administrative territories of the region. Areas of high, medium, low risk of TBE infection are identified. The territories of the city of Tomsk and the Tomsk region, where the maximum infection rates are recorded (66-88 cases per year), are referred to the high-risk zone. Keywords: monitoring, morbidity, tick-borne encephalitis, natural focal infections, intensive indicator.","PeriodicalId":152020,"journal":{"name":"Medical Parasitology and Parasitic Diseases","volume":"24 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127792246","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"СLONORCHIASIS IN PRIMORSKY KRAI","authors":"A. Popov, A. V. Ermolenko, V. Ivanis, T. Homichuk","doi":"10.33092/0025-8326mp2021.3.25-30","DOIUrl":"https://doi.org/10.33092/0025-8326mp2021.3.25-30","url":null,"abstract":"Natural foci of clonorchiasis are localized on the territory of Primorsky Territory. The incidence of clonorchiasis ranged from 0.57 per 100 thousand population in 2014 (10 cases) to 1.5 per 100 thousand in 2012 (28 cases), and in 2010 (35 cases) to 1.9 per 100 thousand population is the maximum level. Analyzed 100 case histories of patients with clonorchiasis. Women predominated (63%). The age of the patients ranged from 3 to 77 years, the average age was 37 years. 82% of cases fell on the age of 18-70 years, 15% - on children from 3 to 18 years old, 3% - people over 70 years old. In 26% of patients, clonorchiasis proceeded in an acute form, in 74% - in a subclinical form. 89% had C. sinensis cleansing after taking praziquantel. Key words: clonorchiasis, acute, chronic, C. sinensis, Primorsky Krai.","PeriodicalId":152020,"journal":{"name":"Medical Parasitology and Parasitic Diseases","volume":"621 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122619295","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}