Journal of Artificial Organs最新文献

筛选
英文 中文
Effect of proactive combination therapy with peritoneal dialysis and hemodialysis on technique survival and mortality. 腹膜透析和血液透析主动联合疗法对技术存活率和死亡率的影响。
IF 1.3 4区 医学
Journal of Artificial Organs Pub Date : 2024-03-22 DOI: 10.1007/s10047-024-01437-z
Kei Nagai, Atsushi Ueda
{"title":"Effect of proactive combination therapy with peritoneal dialysis and hemodialysis on technique survival and mortality.","authors":"Kei Nagai, Atsushi Ueda","doi":"10.1007/s10047-024-01437-z","DOIUrl":"https://doi.org/10.1007/s10047-024-01437-z","url":null,"abstract":"<p><strong>Purpose: </strong>Clinically relevant evidence for the timing of starting combination therapy with peritoneal dialysis and hemodialysis remains scarce. We retrospectively examined whether combination therapy during the induction phase of dialysis prolongs peritoneal dialysis duration.</p><p><strong>Methods: </strong>This retrospective study includes 160 patients who underwent combination therapy from 20 dialysis facilities. Four groups were categorized: combination at peritoneal dialysis induction (n = 12, Proactive combination group), and combination following peritoneal dialysis durations of < 2 years (n = 65), 2-5 years (n = 70), or > 5 years (n = 13). Differences in technique survival of dialysis, mortality, and hospitalization due to cardiovascular events in the groups were observed.</p><p><strong>Results: </strong>The Proactive combination group had the longer mean duration of combination therapy (3.18 years) comparing to that of combination therapy following peritoneal dialysis (1.45 years), but total peritoneal dialysis duration was shorter than in control groups (4.02 years). Of the 160 cases in the entire cohort, there were 8 deaths, 18 ischemic heart disease hospitalizations, and 18 stroke hospitalizations. The Proactive group had lower crude mortality rate (0/12 cases, 0.0%) and crude hospitalization rate for ischemic heart disease (1/11, 8.3%) than the other groups. However, this cohort study did not have enough statistical power to adjust for patients' background, and we were unable to fully examine the differences in such clinical outcomes by the timing of initiation of combination therapy.</p><p><strong>Conclusion: </strong>Use of combination therapy in the induction phase might prolong the duration of combination therapy, but is not necessarily effective for prolonging peritoneal dialysis technique survival.</p>","PeriodicalId":15177,"journal":{"name":"Journal of Artificial Organs","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2024-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140184498","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Utilizing a long sheath to minimize atheroma manipulation (minimal manipulation approach) during Zone 1 and 2 thoracic endovascular aortic repair with a shaggy aorta. 在 1 区和 2 区胸腔内血管主动脉修补术中,利用长鞘管尽量减少对粥样斑块的操作(最小操作法)。
IF 1.3 4区 医学
Journal of Artificial Organs Pub Date : 2024-03-21 DOI: 10.1007/s10047-024-01440-4
Hidetake Kawajiri, Takuma Kobayashi, Kaichiro Manabe, Keiichi Kanda, Satoshi Numata
{"title":"Utilizing a long sheath to minimize atheroma manipulation (minimal manipulation approach) during Zone 1 and 2 thoracic endovascular aortic repair with a shaggy aorta.","authors":"Hidetake Kawajiri, Takuma Kobayashi, Kaichiro Manabe, Keiichi Kanda, Satoshi Numata","doi":"10.1007/s10047-024-01440-4","DOIUrl":"https://doi.org/10.1007/s10047-024-01440-4","url":null,"abstract":"<p><p>We have adopted a simple and reproducible approach, \"minimal manipulation approach,\" since January 2021 in five patients to minimize the risk of thromboembolic events during Zone 1 and 2 thoracic endovascular aortic repair (TEVARs) with shaggy aorta. The approach consists of two parts: ① Use of a 65-cm-long sheath (dry seal) to deliver the endografts without touching the protruding atheroma. Covering the atheroma with the first endograft delivered at Zone 3 to the mid-descending aorta (paving the aorta), and second endograft insertion and deployment through the paved aorta with first endograft. ② Protection of the left subclavian artery using balloon catheter during TEVAR. No in-hospital mortality was recorded, and none of the patients had stroke, spinal cord ischemia, or distal embolic events.</p>","PeriodicalId":15177,"journal":{"name":"Journal of Artificial Organs","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2024-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140184499","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Predictive role of regional thigh tissue oxygen saturation monitoring during cardiopulmonary bypass in lung injury after cardiac surgery 心肺旁路过程中大腿区域组织氧饱和度监测对心脏手术后肺损伤的预测作用
IF 1.3 4区 医学
Journal of Artificial Organs Pub Date : 2024-03-18 DOI: 10.1007/s10047-024-01438-y
Tomoki Tamura, Fumiaki Shikata, Tadashi Kitamura, Masaomi Fukuzumi, Yuki Tanaka, Tomoyo Ebine, Kiyotaka Fujii, Satoshi Kohira, Kagami Miyaji
{"title":"Predictive role of regional thigh tissue oxygen saturation monitoring during cardiopulmonary bypass in lung injury after cardiac surgery","authors":"Tomoki Tamura, Fumiaki Shikata, Tadashi Kitamura, Masaomi Fukuzumi, Yuki Tanaka, Tomoyo Ebine, Kiyotaka Fujii, Satoshi Kohira, Kagami Miyaji","doi":"10.1007/s10047-024-01438-y","DOIUrl":"https://doi.org/10.1007/s10047-024-01438-y","url":null,"abstract":"<p>Acute respiratory distress syndrome (ARDS) is a serious complication following cardiac surgery mainly associated with the use of cardiopulmonary bypass (CPB), which could increase the risk of mortality and morbidity. This study investigated the association of regional oxygen saturation (rSO<sub>2</sub>) during CPB with postoperative outcomes, including respiratory function. Patients who underwent cardiac surgery with CPB from 2015 to 2019 were included. Near-infrared spectroscopy was used to monitor rSO<sub>2</sub> at the forehead, abdomen, and thighs throughout the surgery. Postoperative markers associated with CPB were assessed for correlations with PaO<sub>2</sub>/FiO<sub>2</sub> (P/F) ratios at intensive care unit (ICU) admission. Postoperative lung injury (LI) was defined as moderate or severe ARDS based on the Berlin criteria, and its incidence was 29.9% (20/67). On multiple regression analysis, the following were associated with P/F ratios at ICU admission: vasoactive-inotropic scores at CPB induction (<i>P</i> = 0.03), thigh rSO<sub>2</sub> values during CPB (<i>P</i> = 0.04), and body surface area (<i>P</i> &lt; 0.001). A thigh rSO<sub>2</sub> of 71% during CPB was significantly predictive of postoperative LI with an area under the curve of 0.71 (<i>P</i> = 0.03), sensitivity of 0.70, and specificity of 0.68. Patients with postoperative LI had longer ventilation time and ICU stays. Thigh rSO<sub>2</sub> values during CPB were a potential predictor of postoperative pulmonary outcomes.</p>","PeriodicalId":15177,"journal":{"name":"Journal of Artificial Organs","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2024-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140149965","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Left ventricular assist devices: yesterday, today, and tomorrow. 左心室辅助装置:昨天、今天和明天。
IF 1.3 4区 医学
Journal of Artificial Organs Pub Date : 2024-03-07 DOI: 10.1007/s10047-024-01436-0
Athanasios Tsiouris, Mark S Slaughter, Ashok Kumar Coimbatore Jeyakumar, Adam N Protos
{"title":"Left ventricular assist devices: yesterday, today, and tomorrow.","authors":"Athanasios Tsiouris, Mark S Slaughter, Ashok Kumar Coimbatore Jeyakumar, Adam N Protos","doi":"10.1007/s10047-024-01436-0","DOIUrl":"https://doi.org/10.1007/s10047-024-01436-0","url":null,"abstract":"<p><p>The shortcomings of expense, power requirements, infection, durability, size, and blood trauma of current durable LVADs have been recognized for many years. The LVADs of tomorrow aspire to be fully implantable, durable, mitigate infectious risk, mimic the pulsatile nature of the native cardiac cycle, as well as minimize bleeding and thrombosis. Power draw, battery cycle lifespan and trans-cutaneous energy transmission remain barriers to completely implantable systems. Potential solutions include decreases in pump electrical draw, improving battery lifecycle technology and better trans-cutaneous energy transmission, potentially from Free-range Resonant Electrical Energy Delivery. In this review, we briefly discuss the history of LVADs and summarize the LVAD devices in the development pipeline seeking to address these issues.</p>","PeriodicalId":15177,"journal":{"name":"Journal of Artificial Organs","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2024-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140049549","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparison of the pre-dilution and post-dilution methods for online hemodiafiltration. 在线血液渗滤的预稀释法和后稀释法的比较。
IF 1.3 4区 医学
Journal of Artificial Organs Pub Date : 2024-03-01 Epub Date: 2023-04-03 DOI: 10.1007/s10047-023-01391-2
Yusuke Kawai, Kazuya Maeda, Misaki Moriishi, Hideki Kawanishi, Takao Masaki
{"title":"Comparison of the pre-dilution and post-dilution methods for online hemodiafiltration.","authors":"Yusuke Kawai, Kazuya Maeda, Misaki Moriishi, Hideki Kawanishi, Takao Masaki","doi":"10.1007/s10047-023-01391-2","DOIUrl":"10.1007/s10047-023-01391-2","url":null,"abstract":"<p><p>Online hemodiafiltration (OL-HDF) is a treatment modality using diffusion and ultrafiltration. There are two types of dilution methods in OL-HDF: pre-dilution, which is commonly provided in Japan, and post-dilution, which is commonly provided in Europe. The optimal OL-HDF method for individual patients is not well studied. In this study, we compared the clinical symptoms, laboratory data, spent dialysate, and adverse events of pre- and post-dilution OL-HDF. We conducted a prospective study of 20 patients who underwent OL-HDF between January 1, 2019 and October 30, 2019. Their clinical symptoms and dialysis efficacy were evaluated. All patients underwent OL-HDF every 3 months in the following sequence: first pre-dilution, post-dilution, and second pre-dilution. We evaluated 18 patients for the clinical study and 6 for the spent dialysate study. No significant differences in spent dialysates regarding small and large solutes, blood pressure, recovery time, and clinical symptoms were observed between the pre- and post-dilution methods. However, the serum α1-microglobulin level in post-dilution OL-HDF was lower than that in pre-dilution OL-HDF (first pre-dilution: 124.8 ± 14.3 mg/L; post-dilution: 116.6 ± 13.9 mg/L; second pre-dilution: 125.8 ± 13.0 mg/L; first pre-dilution vs. post-dilution, post-dilution vs. second pre-dilution, and first pre-dilution vs. second pre-dilution: p = 0.001, p < 0.001, and p = 1.000, respectively). The most common adverse event was an increase in transmembrane pressure in the post-dilution period. Compared to pre-dilution, the post-dilution method decreased the α1-microglobulin level; however, there were no significant differences in clinical symptoms or laboratory data.</p>","PeriodicalId":15177,"journal":{"name":"Journal of Artificial Organs","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9235668","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Successful trans-femoral retrieval of a stuck axillary Impella 5.0 device. 成功经股动脉取出卡在腋下的 Impella 5.0 装置。
IF 1.3 4区 医学
Journal of Artificial Organs Pub Date : 2024-03-01 Epub Date: 2022-11-27 DOI: 10.1007/s10047-022-01373-w
Yusuke Hamada, Kazuo Shimamura, Keiwa Kin, Takuji Kawamura, Noriyuki Kashiyama, Koichi Toda, Yoshiki Sawa, Shigeru Miyagawa
{"title":"Successful trans-femoral retrieval of a stuck axillary Impella 5.0 device.","authors":"Yusuke Hamada, Kazuo Shimamura, Keiwa Kin, Takuji Kawamura, Noriyuki Kashiyama, Koichi Toda, Yoshiki Sawa, Shigeru Miyagawa","doi":"10.1007/s10047-022-01373-w","DOIUrl":"10.1007/s10047-022-01373-w","url":null,"abstract":"<p><p>We describe a case in which an axillary Impella 5.0, stuck in an area of calcification in the right subclavian artery, could not be retrieved in the usual manner. However, it was successfully removed using a long 22-Fr sheath and snaring catheter by means of the trans-femoral artery. Device retrieval using the trans-femoral artery snare technique is considered a valid option for removing the Impella device in patients who exhibit this complication.</p>","PeriodicalId":15177,"journal":{"name":"Journal of Artificial Organs","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40722504","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Successful treatment of diabetic ketoacidosis secondary to fulminant type 1 diabetes mellitus using a closed-loop artificial pancreas in a pediatric patient. 使用闭环人工胰腺成功治疗一名儿童患者因暴发性 1 型糖尿病而引发的糖尿病酮症酸中毒。
IF 1.3 4区 医学
Journal of Artificial Organs Pub Date : 2024-03-01 Epub Date: 2022-12-13 DOI: 10.1007/s10047-022-01378-5
Takahiko Tamura, Tsukasa Tadokoro, Hideki Iwata, Tsutomu Namikawa, Kazuhiro Hanazaki, Takashi Kawano
{"title":"Successful treatment of diabetic ketoacidosis secondary to fulminant type 1 diabetes mellitus using a closed-loop artificial pancreas in a pediatric patient.","authors":"Takahiko Tamura, Tsukasa Tadokoro, Hideki Iwata, Tsutomu Namikawa, Kazuhiro Hanazaki, Takashi Kawano","doi":"10.1007/s10047-022-01378-5","DOIUrl":"10.1007/s10047-022-01378-5","url":null,"abstract":"<p><p>Diabetic ketoacidosis (DKA) is a life-threatening complication of pediatric diabetes mellitus (DM). A bedside closed-loop artificial pancreas (AP) (STG-55; NIKKISO, Tokyo, Japan) maintains the blood glucose (BG) levels within the target range via automatic infusion of insulin and glucose. We report the application of the closed-loop AP to safely control the BG levels of a pediatric patient with DKA. A 12-year-old child with an unremarkable medical history presented with fever and restlessness. The patient was diagnosed with DKA secondary to fulminant type 1 DM and was treated with insulin infusion. He presented with Glasgow Coma Scale of E2V3M4. Arterial blood gas analysis revealed metabolic acidosis and BG levels of 489 mg/dL. His urine test was positive for ketones. Along with infusion therapy, automatic BG control using a closed-loop AP was initiated after ICU admission. This was adjusted to maintain BG levels within 100 mg/dL/6 h or less. After 24 h in the ICU, the patient regained consciousness and recovered from the metabolic acidosis. His general condition improved, and he was prescribed a diet treatment. The treatment was shifted to continuous insulin infusion, and he was transferred to the general ward, and was discharged on the 33rd day of hospitalization. The closed-loop AP prevented repetitive blood extractions, achieved prompt glycemic control, and prevented cerebral edema in a pediatric patient with DKA. This is the first report of successful treatment of DKA using a bedside closed-loop AP.</p>","PeriodicalId":15177,"journal":{"name":"Journal of Artificial Organs","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10700241","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Left ventricular remodeling and long-term outcomes of aortic stenosis patients receiving 19 mm Mosaic. 接受 19 毫米 Mosaic 治疗的主动脉瓣狭窄患者的左心室重塑和长期预后。
IF 1.3 4区 医学
Journal of Artificial Organs Pub Date : 2024-03-01 Epub Date: 2023-03-29 DOI: 10.1007/s10047-023-01390-3
Daijiro Hori, Takahiro Yamamoto, Naoyuki Kimura, Atsushi Yamaguchi
{"title":"Left ventricular remodeling and long-term outcomes of aortic stenosis patients receiving 19 mm Mosaic.","authors":"Daijiro Hori, Takahiro Yamamoto, Naoyuki Kimura, Atsushi Yamaguchi","doi":"10.1007/s10047-023-01390-3","DOIUrl":"10.1007/s10047-023-01390-3","url":null,"abstract":"<p><p>Mosaic valve shows higher pressure gradient after aortic valve replacement compared to other same size labeled prostheses in postoperative echocardiogram. The purpose of this study was to evaluate the mid-term echocardiogram findings and long-term clinical outcomes of patients receiving a 19 mm Mosaic. Forty-six aortic stenosis patients receiving 19 mm Mosaic and 112 patients receiving either 19 mm Magna or Inspiris, who underwent mid-term follow-up echocardiogram were included in the study. Mid-term hemodynamic measurements evaluated by trans-thoracic echocardiogram and long-term outcomes were compared. Patients receiving Mosaic were significantly older (Mosaic: 76 ± 5.1 years vs. Magna/Inspiris: 74 ± 5.5 years, p = 0.046) and had smaller body surface area (Mosaic: 1.40 ± 0.114m<sup>2</sup> vs. Magna/Inspiris: 1.48 ± 0.143m<sup>2</sup>, p < 0.001). There were no significant differences in comorbidities and medications. Post-operative echocardiogram performed at 1 week after the surgery showed higher maximum pressure gradient in patients receiving Mosaic (Mosaic: 38 ± 13.5 mmHg vs. Magna/Inspiris: 31 ± 10.7 mmHg, p = 0.002). Furthermore, mid-term echocardiogram follow-up performed at median duration of 53 ± 14.9 months after the surgery continuously showed higher maximum pressure gradient in patients receiving Mosaic (Mosaic: 45 ± 15.6 mmHg vs. Magna/Inspiris: 32 ± 13.0 mmHg, p < 0.001). However, there were no significant difference in changes in left ventricular mass from baseline in both groups. Kaplan-Meyer curve also showed no difference in long-term mortality and major adverse cardiac and cerebrovascular event between the two groups. Although the pressure gradient across the valve evaluated by echocardiogram was higher in 19 mm Mosaic compared to 19 mm Magna/Inspiris, there were no significant differences in left ventricular remodeling and long-term outcomes between the two groups.</p>","PeriodicalId":15177,"journal":{"name":"Journal of Artificial Organs","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9203855","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The effect of balloon-expandable stent and self-expanding stent on changes in mitral annular motion after aortic valve replacement in patients with aortic stenosis. 主动脉瓣狭窄患者主动脉瓣置换术后球囊扩张支架和自扩张支架对二尖瓣环运动变化的影响。
IF 1.3 4区 医学
Journal of Artificial Organs Pub Date : 2024-03-01 Epub Date: 2023-02-04 DOI: 10.1007/s10047-023-01384-1
Daijiro Hori, Yohei Nomura, Yosuke Taniguchi, Koichi Yuri, Makiko Mieno, Naoyuki Kimura, Atsushi Yamaguchi
{"title":"The effect of balloon-expandable stent and self-expanding stent on changes in mitral annular motion after aortic valve replacement in patients with aortic stenosis.","authors":"Daijiro Hori, Yohei Nomura, Yosuke Taniguchi, Koichi Yuri, Makiko Mieno, Naoyuki Kimura, Atsushi Yamaguchi","doi":"10.1007/s10047-023-01384-1","DOIUrl":"10.1007/s10047-023-01384-1","url":null,"abstract":"<p><strong>Objectives: </strong>The purpose of this study was to evaluate the effect of decalcification and existence of stent at the aortic annulus on mitral annular motion after surgery.</p><p><strong>Methods: </strong>Patients receiving Inspiris (Edwards, CA, USA, n = 117), Intuity (Edwards, n = 36), Perceval (Corcym, London, UK, n = 36), Evolut (Medtronics, MN, USA, n = 81) and Sapien 3 (Edwards, n = 250) were included in the study. Mitral annular motion was evaluated by E', using tissue doppler imaging.</p><p><strong>Results: </strong>After surgery, a significant increase in E' was observed in patients receiving Inspiris (Before: 4.2 ± 1.21 cm/s vs. Discharge: 5.0 ± 1.23 cm/s, p < 0.001). Mid-term echocardiogram performed at 11.8 ± 2.2 months after the surgery, showed a significant increase in E' in patients receiving Inspiris (Before: 4.2 ± 1.21 cm/s vs. Mid-term: 5.2 ± 1.20 cm/s, p < 0.001) and Perceval (Before: 3.9 ± 1.34 cm/s vs. Mid-term: 4.5 ± 1.24 cm/s, p = 0.008). Univariable analysis showed a higher increase in E' in patients with decalcified annulus compared to those without decalcified annulus (Decalcification: 0.15 ± 1.321 cm/s vs. No Decalcification: 0.66 ± 1.420 cm/s, p < 0.001). Multivariable analysis showed that balloon-expandable stent (β = - 0.6960, p < 0.001) and self-expanding stent (r = - 0.3592, p = 0.042) were independent limiting factors for an increase in E' at discharge. However, balloon-expandable stent (β = - 0.8382, p < 0.001), and not self-expanding stent (β = - 0.3682, p = 0.089), was a remaining independent factor associated with E' at mid-term follow-up.</p><p><strong>Conclusions: </strong>Decalcification was associated with improvement in E' after surgery. Balloon-expandable stent was an independent limiting factor for improvement in E' up to 1 year after the surgery, while self-expanding stent was not a significant factor after 1 year.</p>","PeriodicalId":15177,"journal":{"name":"Journal of Artificial Organs","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10645777","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Investigation of the inhibition of bacteria and endotoxin influx by back filtration through dialyzer membranes. 通过透析膜反向过滤抑制细菌和内毒素流入的研究。
IF 1.3 4区 医学
Journal of Artificial Organs Pub Date : 2024-03-01 Epub Date: 2023-02-10 DOI: 10.1007/s10047-023-01385-0
Tadashi Tomo, Kazuhiro Matsuyama, Junichi Michikoshi, Katsuhiro Hanada
{"title":"Investigation of the inhibition of bacteria and endotoxin influx by back filtration through dialyzer membranes.","authors":"Tadashi Tomo, Kazuhiro Matsuyama, Junichi Michikoshi, Katsuhiro Hanada","doi":"10.1007/s10047-023-01385-0","DOIUrl":"10.1007/s10047-023-01385-0","url":null,"abstract":"<p><p>We investigated the usefulness of assays using human neutrophils for radical production as well as endotoxin (ET) measurement and bacterial culture for endotoxin and bacterial influx by back filtration using dialyzers with different membrane pore diameters. Three types of dialyzers made of cellulose triacetate membrane material with different pore size FB-110EG eco, FB-110U eco, and FB-150UHβ eco were used. A circuit to generate back filtration was created. Back filtrate generated by hydraulic head pressure operation was collected. ET and bacteria were examined. Human neutrophils were exposed to back filtrate (experiments using three different membranes) and contaminated solution, and free radical production was measured using LBP-953 (Berthold) to see if there were differences in production. No bacteria were detected and the concentration of endotoxin was below the detection limit in the back filtrate from the three types of membranes and purified water. Free radical production from neutrophils in the contaminated water was highest at 4,405,750 ± 61,244 cpm (counts per minute) (mean ± SD) (P < 0.01 vs FB-150UHβ eco, FB-110U-eco, and FB-110EG eco) followed by that in back filtrate via FB-150UHβ eco, FB-110U-eco, FB-110EG eco. Radical production from neutrophils was thereby higher in the back filtrate of dialyzers with larger pore-size membranes. No bacteria were observed and the concentration of ET was below the detection limit in back filtrate from any of the membranes. However, when the reverse filtrate was exposed to neutrophils, radical production increased along with pore size, suggesting the influx of small pyrogens and other pyrogenic substances.</p>","PeriodicalId":15177,"journal":{"name":"Journal of Artificial Organs","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9238324","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信