{"title":"Application of Substrate Materials Derived from Plant Roots, Stems, Leaves, and Microbes for Remediation of Soil Heavy Metal Pollution","authors":"Shujiao Liu, Weizhong Liu, Yonggang Zhang","doi":"10.1166/jbmb.2024.2333","DOIUrl":"https://doi.org/10.1166/jbmb.2024.2333","url":null,"abstract":"This study focuses on the remediation of chromium (Cr), a heavy metal, in soil using substrate materials synthesized from plant roots, stems, leaves, and microbes. Corn was chosen as the source material for biochar production through high-temperature pyrolysis of corn roots, stems, and leaves. The biochar was then modified with an iron solution, and microbial adsorption was employed to remediate heavy metal Cr in the soil. The study involved physical and infrared analyses of the substrate materials and experiments to determine the adsorption contribution of different pH conditions, sites, and substrate materials to metal Cr. The effectiveness of plant roots, stems, leaves, and microbial combinations in remediating soil heavy metal pollution was verified. The experimental results demonstrate a decrease in the Zeta potential values of both materials as the pH increases. Moreover, as pH gradually increases, the form of Cr ions changes, and the reproductive ability of microbes weakens. The substrate materials exhibit a notable increase in negative charge, leading to enhanced repulsion towards Cr, which impacts their adsorption performance. At neutral pH, the adsorption capacity of the substrate materials for Cr is enhanced. The contribution rate of the composite substrate materials in the adsorption process is 6.78%, while that of microbial organisms is 56.45%, significantly higher than that of Fe-CBC. The main reason is that microbial adsorption activity for Cr is enhanced under higher pH conditions, with the contribution rate of microbial organisms continuing to increase significantly at a pH of 9.","PeriodicalId":15157,"journal":{"name":"Journal of Biobased Materials and Bioenergy","volume":"30 1","pages":""},"PeriodicalIF":0.5,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139126629","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ningbo Yang, Hongxia Hu, Jie Li, Shaoli Shi, Yuling Wei, Yanhong Li, Wenwen Sun
{"title":"Influence and Mechanism of Traditional Chinese Medicine Intervention on Cognitive Dysfunction in Patients with Schizophrenia","authors":"Ningbo Yang, Hongxia Hu, Jie Li, Shaoli Shi, Yuling Wei, Yanhong Li, Wenwen Sun","doi":"10.1166/jbmb.2024.2342","DOIUrl":"https://doi.org/10.1166/jbmb.2024.2342","url":null,"abstract":"This study investigates the impact and mechanisms of traditional Chinese medicine (TCM) intervention in patients with schizophrenia. In animal experiments, a total of 48 rats were randomly divided into four groups: control group (CG), model group (MG), Albizia flower flavonoid group (AFFG), and clozapine group (CLG). Each group consisted of 12 rats. After treatment, MK-801 was administered to the MG, AFFG, and CLG to establish schizophrenia rat models, while the CG received physiological saline. Cognitive abilities, hippocampal pathology, and protein expression were evaluated, and the expression levels of c-fos, cleaved Caspase-3, Bcl-2, and Bax were determined. In clinical trials, the study included 82 patients with schizophrenia treated at our hospital from February 2022 to February 2023. They were divided into the observation group (OG) and the experimental group (EG), with 41 cases in each group. The EG received aripiprazole and self-formulated TCM decoction, while the OG received aripiprazole. The PANSS scores and quality of life levels were compared. The results revealed impaired cognition, altered protein expression, and increased pathology in the MG compared to the CG. The AFFG and CLG exhibited enhanced cognition, improved protein expression, and reduced pathology when compared to the MG. Clinical findings demonstrated significantly lower PANSS scores and improved quality of life in the EG compared to the OG. In conclusion, Albizia flower flavonoids effectively modulated protein expression, ameliorated cognitive dysfunction, and reduced pathology. Additionally, the decoction decoction enhanced cognition and quality of life in patients with schizophrenia, suggesting promising clinical applications.","PeriodicalId":15157,"journal":{"name":"Journal of Biobased Materials and Bioenergy","volume":"115 3","pages":""},"PeriodicalIF":0.5,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139128535","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Danshen-Chuanxiongqin Injection for Enhanced Management of Neurological Function in Elderly Patients with Acute Ischemic Stroke","authors":"Ling Zhong, Zihong Zhao","doi":"10.1166/jbmb.2024.2334","DOIUrl":"https://doi.org/10.1166/jbmb.2024.2334","url":null,"abstract":"This study investigates the pharmacological properties of Danshen-Chuanxiongqin Injection and the impact of an evidence-based nursing model based on an innovative diffusion theory framework on neurological function in elderly patients with acute ischemic stroke. The stability of the injection was assessed via ultra-high-performance liquid chromatography coupled with quadrupole/orbitrap high-resolution mass spectrometry. The pharmacological properties of the injection were evaluated in three groups of rats: Group A (Cold coagulation and blood stasis), Group B (Blood stasis with sthenia), and Group C (Normal control). Groups A and B were further divided into subgroups receiving either physiological saline or the injection, followed by an analysis of hemorheological parameters. 200 elderly patients with acute ischemic stroke were divided into two groups: a control group (evidence-based nursing model based on the innovative diffusion theory framework) and an observation group (Danshen-Chuanxiongqin Injection+evidence-based nursing model based on the innovative diffusion theory framework). Medication quality was confirmed using SPSS 26.0. In animal experiments, Group B displayed improved hemorheology, adverse drug reaction, and thyroidstimulating hormone levels (P < 0.05). The observation group exhibited reduced post-treatment plasma renin activity, angiotensin II, aldosterone, and norepinephrine. At the treatment end and 6-month follow-up, the observation group showed significantly improved neurological function (P < 0.05). The injection demonstrated stable pharmacological properties with a cooling effect, effectively treating blood stasis with sthenia-related symptoms. The evidence-based nursing model with the innovative diffusion theory framework effectively enhanced neurological function, neuroendocrine hormones, clinical efficacy, and safety in elderly patients with acute ischemic stroke. This approach holds promise for further implementation and promotion.","PeriodicalId":15157,"journal":{"name":"Journal of Biobased Materials and Bioenergy","volume":"8 11","pages":""},"PeriodicalIF":0.5,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139126727","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Catalytic Synthesis of Carbon Nanotubes and Hydrogen Gas from Waste Plastics Using LaNiO3 Perovskite Catalyst","authors":"Tian Qi, Runfeng Tian, Youjian Zhu, Chuanxiao Cheng, Shuhua Yang, Xiaorui Hu, Lanlan Jiang, Yanqiu Xiao","doi":"10.1166/jbmb.2024.2341","DOIUrl":"https://doi.org/10.1166/jbmb.2024.2341","url":null,"abstract":"Using waste plastic syngas to prepare carbon nanotubes (CNTs) and hydrogen-rich gas is a clean and efficient recycling method for waste plastics, and it is very important to find out how to improve its yield and quality. In this work, CNTs and hydrogen-rich gas were prepared by LaNiO3 perovskitetype catalysts from waste plastic syngas model compound in laboratory. The LaNiO3 catalysts, carbon nanotubes and gas fractions produced at different temperatures were characterized and compared with the supported catalyst Ni/ZSM-5. The main conclusions were as follows: 650 °C catalytic temperature had maximum carbon nanotubes yield of 5.84 gCNTs/gCatalyst and H2 content of 44 Vol.%, which was 4.44 times the carbon nanotubes yield from the Ni/ZSM-5 catalyst at the same temperature case. A bottom growth pattern of carbon nanotubes produced on the LaNiO3 catalyst was observed by high resolution transmission electron microscopy (HRTEM). The X-ray crystal diffractometer (XRD) analysis revealed that the interaction force between Ni and the carrier was stronger in LaNiO3 than that of the Ni/ZSM-5 catalyst, resulting in two different growth patterns of carbon nanotubes. The present experiments probe that the LaNiO3 catalysts have a greater prospect of application in the preparation of CNTs and hydrogen-rich gas from waste plastic syngas.","PeriodicalId":15157,"journal":{"name":"Journal of Biobased Materials and Bioenergy","volume":"34 13","pages":""},"PeriodicalIF":0.5,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139127074","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
X. Qi, Zeguang Du, Fengqin Zhang, Meilan Li, Gaizhen Li
{"title":"Genome-Wide Identification of BrassinaZole Resistant (BZR) Gene Family in Brassica rapa ssp. pekinensis and Its Expression Pattern During Flowering Process","authors":"X. Qi, Zeguang Du, Fengqin Zhang, Meilan Li, Gaizhen Li","doi":"10.1166/jbmb.2024.2349","DOIUrl":"https://doi.org/10.1166/jbmb.2024.2349","url":null,"abstract":"The BrassinaZole Resistant (BZR) gene family mediates the signal transduction of brassinolide, which is vital in regulating vegetative and reproductive growth of plants. In this research, a comprehensive analysis of all candidate BrBZR genes in Chinese cabbage (Brassica rapa ssp. pekinensis) was conducted using bioinformatics methods, including protein physicochemical properties, evolutionary relationship, gene structure, and conserved domains. Additionally, these candidate genes’ expression patterns during flowering development were analyzed utilizing transcriptome data, and key genes that regulate flowering of Chinese cabbage were screened. In the results, 14 BrBZR genes were identified, with coding sequence (CDS) lengths of 460–1162 bp, and encoding proteins of 152–386 amino acids. The majority of BrBZRs had a highly conserved motif 1 as well as numerous regulatory elements associated with hormone and abiotic stress responses. Transcriptome sequencing showed that 12 BrBZRs were expressed during the flowering development, among which BrBES1.1 and BrBES1.2 were highly expressed, with FPKM ranges of 61.78–99.91 and 43.71–76.69, respectively. Their expression was upregulated during vernalization and flower bud differentiation, suggesting that they may play a key role in regulating the flowering process of Chinese cabbage. Overall, our study provides comprehensive insights into the BrBZR gene family, and has important implications for the further elucidation of the mechanisms that regulate flower development in Chinese cabbage and potentially other related Brassica species.","PeriodicalId":15157,"journal":{"name":"Journal of Biobased Materials and Bioenergy","volume":"28 3","pages":""},"PeriodicalIF":0.5,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139127855","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lu Yang, Shaoli Fan, Jiuyang Zhao, Jinfa Liao, Yicun Chen, Yangdong Wang
{"title":"Comparative Metabolomics Revealed Differences in Alkaloids Metabolism Between Morus nigra L. and Morus. alba L. at Different Growth Stages","authors":"Lu Yang, Shaoli Fan, Jiuyang Zhao, Jinfa Liao, Yicun Chen, Yangdong Wang","doi":"10.1166/jbmb.2024.2347","DOIUrl":"https://doi.org/10.1166/jbmb.2024.2347","url":null,"abstract":"Mulberry (Morus spp.), a flowering plant in the Moraceae family, is known for the edible fruit, and mulberry leaves have various applications. This experiment utilized ultra-high performance liquid chromatography-quadrupole time of flight mass spectrometry (UPLC-Q-TOF-MS) and Progenesis QI software to rapidly identify secondary metabolites in the leaves of Morus nigra L. and Morus alba L.. Orthogonal partial least squares discriminant analysis (OPLS-DA), principal component analysis (PCA) and Hierarchical clustering analysis (HCA) were used to examine the dynamic changes and stage specificity of metabolites, particularly alkaloids, in M. nigra and M. alba leaves during seven primary growth stages. In results, the leaf samples from different growth stages uncovered a total of 182 metabolites from 13 distinct categories. M. nigra had significantly higher levels of metabolites than those in M. alba, according to differences in leaf metabolite accumulation patterns. Multiple statistical analyses revealed that the metabolome of M. nigra and M. alba leaves exhibited a significant interspecific and developmental specific accumulation patterns, with most DNJ alkaloids having the highest content in M. nigra leaves. In different growth stages, the metabolites of M. nigra leaves showed significant stage specificity. During the development stage of small fruit stage, obvious changes occurred in the chemical composition of M. nigra leaves, with a significant increase in DNJ alkaloid metabolites. Overall, this study provides a theoretical reference for the comprehensive development and sustainable utilization of M. nigra resources in Xinjiang.","PeriodicalId":15157,"journal":{"name":"Journal of Biobased Materials and Bioenergy","volume":"65 8","pages":""},"PeriodicalIF":0.5,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139127573","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yantao Yang, Yuanna Li, Wenkai Yang, Xiunan Cui, Tingzhou Lei
{"title":"Preparation and Surface Modification of Nanocellulose and Its Adsorption Performance on Cu2+","authors":"Yantao Yang, Yuanna Li, Wenkai Yang, Xiunan Cui, Tingzhou Lei","doi":"10.1166/jbmb.2024.2296","DOIUrl":"https://doi.org/10.1166/jbmb.2024.2296","url":null,"abstract":"Nanocellulose fibers (NCFs) were converted to cellulose nanocrystals (CNCs) and then modified with diethylenetriamine pentaacetic acid (DTPA) to form modified CNCs (DTPA–CNCs), which were investigated as adsorbents for removing Cu2+ from aqueous solution. The adsorption behavior was affected by pH, contact time, dosage and raw Cu2+ concentration. Langmuir model is the best method to fit the adsorption isotherm of experimental results. The optimal conditions for Cu2+ adsorption were 2 h at 35 °C and pH 3, the optimal adsorption capacity is 94.5 mg/g. These functional groups on the DTPA–CNCs provided enhanced adsorption capacity, compared with unmodified NCFs.","PeriodicalId":15157,"journal":{"name":"Journal of Biobased Materials and Bioenergy","volume":"52 20","pages":""},"PeriodicalIF":0.5,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139125417","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Physiological Responses and Salt Tolerance Evaluation of Purple-Leaf Berberis (Berberis thunbergii var. Atropurpurea) and Glacier Red-Leaf Berberis (Berberis thunbergii) Under NaCl Stress","authors":"Yan Li, Dongyun Liu, Shaohua Du, Bingshe Lu","doi":"10.1166/jbmb.2024.2352","DOIUrl":"https://doi.org/10.1166/jbmb.2024.2352","url":null,"abstract":"This study investigated the impact of various concentrations of NaCl stress treatment (0%, 0.1%, 0.2%, 0.3%, 0.4%) on the growth of one-year-old saplings of purple leaf barberry and glacier red leaf barberry. It also examined the impact on various physiological responses including plasma membrane permeability, antioxidant protective enzyme system, osmotic regulatory substance content, photosynthetic characteristics, ion content, and the ultrastructure of leaf cells using transmission electron microscopy. The goal was to determine the salt tolerance threshold and elucidate the physiological response mechanism to NaCl stress. The comprehensive assessment of salt tolerance in the two barberries was done using fuzzy membership functions. The results demonstrated that increasing concentrations of NaCl stress and longer treatment durations led to gradual decreases in sapling growth and increases in salt damage index. The salt tolerance thresholds were calculated to be 0.37% for purple leaf barberry and 0.33% for glacier red leaf barberry using the logistic curve equation. The activities of SOD and POD initially increased and then decreased in both barberries. Furthermore, MDA, free proline, and Na+ content gradually increased, while soluble protein content, chlorophyll content, net photosynthetic rate (Pn), K+ content, and K+/Na+ ratio gradually decreased. The purple leaf barberry displayed larger and deformed chloroplasts with significant separation of quality and wall, whereas the glacier red leaf barberry experienced a gradual decrease in chloroplast size and number until degradation. The membership function analysis revealed that purple leaf barberry exhibited superior resistance compared to glacier red leaf barberry.","PeriodicalId":15157,"journal":{"name":"Journal of Biobased Materials and Bioenergy","volume":"7 5","pages":""},"PeriodicalIF":0.5,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139126754","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lu Zhang, T. Sun, Taoli Huhe, Peng Liu, Xueqin Li, Yanling Li, Tingzhou Lei, Yong Chen
{"title":"Overview of Marginal Lands in Henan Province, China and Evaluation of Development Potential of Biomass-To-Liquid Fuels","authors":"Lu Zhang, T. Sun, Taoli Huhe, Peng Liu, Xueqin Li, Yanling Li, Tingzhou Lei, Yong Chen","doi":"10.1166/jbmb.2024.2354","DOIUrl":"https://doi.org/10.1166/jbmb.2024.2354","url":null,"abstract":"Developing marginal lands to plant energy crops and then develop biomass-to-liquid fuels is an effective way to ease the energy crisis, promote greenhouse gas emission reduction, and protect the natural ecological environment. Taking Henan Province, China as a research object, the research obtained spatial distributions and areas of marginal lands in the province by processing remote-sensing data for land use using software ArcGIS. Marginal lands in Henan Province were classified into the first-class, second-class, and third-class ones by selecting key natural conditions including the soil thickness, slope, soil texture (sand volume fraction), accumulated temperature above 10 °C, organic matter content, and total annual precipitation as indices. The research showed that the total area of marginal lands in the province is 1.68×104 km2, including 0.62×104 km2 of first-class marginal lands, 0.83×104 km2 of second-class marginal lands, and 0.23×104 km2 of third-class marginal lands. Taking production of bioethanol with sugar grass as an example, 8.92×107 t of sugar grass can be harvested on the marginal lands in Henan Province, which can be converted into 5.80×106 t of bioethanol, equivalent to 6.96×106 t of standard coal. The research can provide reference for realizing energy structure optimization and consolidating energy security in Henan Province.","PeriodicalId":15157,"journal":{"name":"Journal of Biobased Materials and Bioenergy","volume":"40 34","pages":""},"PeriodicalIF":0.5,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139125506","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Effect of Fast-Track Surgery Nursing Intervention Combined with Probiotic Nutrition Therapy on Children During the Peri-Operative Period of Thoracoscopic Lobectomy","authors":"Wen Tang, Liqing Song, Hui Yang","doi":"10.1166/jbmb.2023.2322","DOIUrl":"https://doi.org/10.1166/jbmb.2023.2322","url":null,"abstract":"This study aims to investigate the feasibility and efficacy of fast-track surgery (FTS) nursing intervention and probiotic nutrition therapy in children during the peri-operative period of precise thoracoscopic lobectomy. A retrospective analysis was conducted on a total of 479 children\u0000 who underwent the surgery at the pediatric department of the West China Hospital, Sichuan University between January 2011 and January 2018. The patients were divided into two groups: the traditional rehabilitation group (A, n = 78) and the rapid rehabilitation group with FTS and probiotic\u0000 nutrition therapy (B, n = 401). No significant differences were observed in general information and the incidence of postoperative complications (P >0.05). However, the B group had significantly reduced early out-of-bed activity time, early resumption of oral feeding time,\u0000 intubation duration, and length of hospital stay (P <0.05). Furthermore, patients in the B group had higher nutritional indexes compared to those in the A group. The levels of Bifidobacterium and Lactobacillus in the B group were higher, while the levels of Enterobacterium\u0000 and Enterococcus were lower than those in the A group. Additionally, the patients and their families in the B group exhibited higher levels of nursing satisfaction (P <0.05). The combination of FTS nursing intervention and probiotic nutrition therapy improved peri-operative\u0000 outcomes without increasing the incidence of complications. Therefore, our findings support the feasibility, safety, and efficacy of thoracoscopic lobectomy with FTS care in pediatric patients, highlighting its potential as a promising surgical intervention.","PeriodicalId":15157,"journal":{"name":"Journal of Biobased Materials and Bioenergy","volume":"123 27","pages":""},"PeriodicalIF":0.5,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138609062","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}