Journal of Biochemistry, Microbiology and Biotechnology最新文献_第7页

Effects Of High Dosage of Codeine - Containing Cough Syrup Administration on Some Biochemical Parameters of Liver in Albino Rats 大剂量含可待因止咳糖浆对白化病大鼠肝脏生化指标的影响

Journal of Biochemistry, Microbiology and Biotechnology Pub Date : 2021-12-31 DOI: 10.54987/jobimb.v9i2.614

Aishatu Muhammad Bello, Ramlatu Musa Adam, F. U. Maigari, Idi Jalil James, Abubakar Aisami

引用次数: 0

Hypoglycemic Effect of Lycopersicon esculentum (Tomato) on Alloxan-Induced Diabetic Rats 番茄对四氧嘧啶诱导的糖尿病大鼠的降糖作用

Journal of Biochemistry, Microbiology and Biotechnology Pub Date : 2021-12-31 DOI: 10.54987/jobimb.v9i2.611

Abubakar Aisami, Jalil Idi James, F. U. Maigari, M. Atiku

{"title":"Hypoglycemic Effect of Lycopersicon esculentum (Tomato) on Alloxan-Induced Diabetic Rats","authors":"Abubakar Aisami, Jalil Idi James, F. U. Maigari, M. Atiku","doi":"10.54987/jobimb.v9i2.611","DOIUrl":"https://doi.org/10.54987/jobimb.v9i2.611","url":null,"abstract":"Diabetes mellitus has been a key degenerative disease affecting the world’s population. Lycopersicon esculentum (Tomato), a fruit consumed by many and known to have certain phytochemicals was used to determine its hypoglycemic effect on alloxan induced diabetic rats. The tomato was dried, pulverized and dissolved in distilled water and administered orally to albino rats in various concentrations according to their body weight. 30 albino rats were divided into 6 groups of 5 rats each. Groups I and II served as normal and diabetic control respectively, while groups III to VI were induced with diabetes and treated with different concentrations of the prepared tomato. After 14 days of treatment with various concentrations of tomato, there was a marked decrease in blood sugar levels at all the study concentrations. The result of the lipid profile a significant increase (p<0.05) in total cholesterol (150.67±7.02 mg/dL), triglyceride (159.33±5.03 mg/dL), LDL-Cholesterol (77.53±1.83 mg/dL) and a decrease in HCL-Cholesterol (51.67±1.00 mg/dL) levels in untreated diabetic rats when compared to the normal control. Upon treatment with 200 mg/kg of tomato, there was a significant decrease (p< 0.05) in the levels of Triglyceride, total cholesterol and LDL-cholesterol and an increase in the HDL-cholesterol. These results suggest that tomato may have the ability to reduce blood sugar level and the risk of cardiovascular disease.","PeriodicalId":15132,"journal":{"name":"Journal of Biochemistry, Microbiology and Biotechnology","volume":"9 46 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73945778","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Biodiesel Production from Cassia tora Seed Oil Through Acid-Base Catalysed Method 酸碱催化决明子油制备生物柴油

Journal of Biochemistry, Microbiology and Biotechnology Pub Date : 2021-07-30 DOI: 10.54987/jobimb.v9i1.571

Hayatuddeen Abubakar, A. Hammari, A. Abubakar, A. Maiwada

{"title":"Biodiesel Production from Cassia tora Seed Oil Through Acid-Base Catalysed Method","authors":"Hayatuddeen Abubakar, A. Hammari, A. Abubakar, A. Maiwada","doi":"10.54987/jobimb.v9i1.571","DOIUrl":"https://doi.org/10.54987/jobimb.v9i1.571","url":null,"abstract":"Biodiesel produced from different triglyceride sources is an alternative fuel to petro-diesel. An investigation was carried out with Cassia tora seed oil. The oil was esterified to reduce the FFA content in the oil and trans-esterification of the oil was carried out which involves making use of methanol and sodium hydroxide pellets in a base-catalyzed trans-esterification reaction. 187g Cassia tora oil was trans-esterified with 20 g of methanol and 0.7 g of NaOH pellets at 55Â°C operating temperature. The outcome was a percentage conversion of 90.53 per cent for Cassia tora feedstock and a by-product of 15.20 g of glycerol (i.e. soap). The physical features of the oil, such as smell and colour, were retained in the biodiesel produced. The density of biodiesel made from Cassia tora oil was determined to be 848.0 kg/m3. The flashpoint was determined to be 135 oC and the acid value and water content were 0.16 (MgKOH/g) and 0.04 (per cent mass), respectively. The kinematic and dynamic viscosities of the generated biodiesel were 4.2mm2/s and 6.49 x 10-3kgm-1s-1, respectively. The pour point was also discovered to be -6 oC. The biodiesel was evaluated using American testing and material standards (ASTM Values). Based on the comparison of measured characteristics with ASTM values, Cassia tora seed oil could be a promising option for biodiesel production","PeriodicalId":15132,"journal":{"name":"Journal of Biochemistry, Microbiology and Biotechnology","volume":"9 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79887578","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Kinetics Modelling of Tributyltin Toxicity on The Growth of Bacillus subtilis 三丁基锡对枯草芽孢杆菌生长毒性的动力学模拟

Journal of Biochemistry, Microbiology and Biotechnology Pub Date : 2021-07-30 DOI: 10.54987/jobimb.v9i1.570

Abdussamad Abubakar

{"title":"Kinetics Modelling of Tributyltin Toxicity on The Growth of Bacillus subtilis","authors":"Abdussamad Abubakar","doi":"10.54987/jobimb.v9i1.570","DOIUrl":"https://doi.org/10.54987/jobimb.v9i1.570","url":null,"abstract":"growth of bacteria. In 2003, the Marine Environmental Protection Committee (MEPC) proposed that TBT be banned internationally due to the negative environmental impacts of the substance. However, even though BTs are banned, they may be found in large quantities in seawater, bottom sediments, and the biota, all of which are contaminated with them. To prevent the adhesion of fouling organisms to the surface of ships and boats, tributyltin (TBT) has been widely employed as an antifouling agent in marine paints for many years. Tributyltin has been discovered to be very persistent, particularly in sediment, and to be extremely harmful to species other than those targeted. Bacillus subtilis growth was intensely inhibited by tributyltin (TBT). As the TBT concentration increases, the overall specific growth rate was inhibited. The growth rates obtained were then modelled according to the modified Han-Levenspiel, Amor, Wang, Liu, Shukor and modified Andrews. Among the five models, the Andrew and Amor models show poor fittings. Results of the statistical analysis showed that the Shukor model was the best model based on the lowest values for RMSE and AICc, highest adjusted correlation coefficient (AdR2) and values of AF and BF closest to unity. The parameters obtained from the Shukor model were Ccrit 742.32 nM (95%, C.I., 303.35 to 1181.29), Î¼max 1.20 h-1 (95% C.I., 1.08 to 1.319) and m 0.507 (95% C.I., 0.308 to 0.832). The findings of this study can be utilized for further bioremediation works.","PeriodicalId":15132,"journal":{"name":"Journal of Biochemistry, Microbiology and Biotechnology","volume":"62 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72626998","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Adsorption Equilibrium and Kinetics Studies of Congo Red Dye Using Groundnut Shell and Sorghum Husk Biosorbent 花生壳和高粱壳生物吸附剂对刚果红染料的吸附平衡及动力学研究

Journal of Biochemistry, Microbiology and Biotechnology Pub Date : 2021-07-30 DOI: 10.54987/jobimb.v9i1.573

A. Hammari, M. I. Misau, U. O. Aroke, U. Hamza, Abdulkarim A. Yusuf

引用次数: 1

Biodegradation of PEGs: A review 聚乙二醇的生物降解研究进展

Journal of Biochemistry, Microbiology and Biotechnology Pub Date : 2021-07-30 DOI: 10.54987/jobimb.v9i1.569

N. Suhaimi, M. Syed, N. A. Shamaan, A. Othman

引用次数: 0

Role of Molecular Diagnostics in The Early Diagnosis of Tuberculous Meningitis 分子诊断在结核性脑膜炎早期诊断中的作用

Journal of Biochemistry, Microbiology and Biotechnology Pub Date : 2021-07-30 DOI: 10.54987/jobimb.v9i1.574

D. Pavan, H. Ravish, S. Nagarathna, M. Nethravathi, K. Seshagiri

{"title":"Role of Molecular Diagnostics in The Early Diagnosis of Tuberculous Meningitis","authors":"D. Pavan, H. Ravish, S. Nagarathna, M. Nethravathi, K. Seshagiri","doi":"10.54987/jobimb.v9i1.574","DOIUrl":"https://doi.org/10.54987/jobimb.v9i1.574","url":null,"abstract":"Although tuberculosis (TB), caused by the bacteria Mycobacterium tuberculosis, affects the lungs in the majority of cases, it can also affect other parts of the body. It is most common in young children and HIV-infected patients, but it can also be found in adults with the condition. The most severe form of tuberculosis, tuberculous meningitis (TBM), is associated with the highest mortality and morbidity rates when compared to other forms of tuberculosis. Despite anti-tuberculosis treatment, tuberculosis-related mortality (TBM) remains a leading cause of death. TBM is difficult to diagnose early using immune-based and molecular-based methods because of the non-specific symptoms that occur in the disease and the low number of bacteria present in the target area, particularly the cerebrospinal fluid (CSF). TBM patients have a high sensitivity and specificity for tuberculosis, but there is currently no established diagnostic method that can detect the infection with high accuracy in a timely manner. In addition, the emergence of drug-resistant Mycobacterium tuberculosis strains complicates the diagnosis and treatment regimen for tuberculous bronchitis. It is the purpose of this review to summarise the difficulties associated with the currently employed molecular-based diagnostic methods as well as the potential future application of molecular diagnostic methods for TBM.","PeriodicalId":15132,"journal":{"name":"Journal of Biochemistry, Microbiology and Biotechnology","volume":"12 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85231839","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Mathematical Modelling of the Growth of Yeast Candida tropicalis TL-F1 on Azo Dyes 热带假丝酵母TL-F1在偶氮染料上生长的数学模型

Journal of Biochemistry, Microbiology and Biotechnology Pub Date : 2021-07-30 DOI: 10.54987/jobimb.v9i1.575

S. Ibrahim, M. Abdulrasheed, H. Ibrahim, Abdussamad Abubakar, H. Yakasai

{"title":"Mathematical Modelling of the Growth of Yeast Candida tropicalis TL-F1 on Azo Dyes","authors":"S. Ibrahim, M. Abdulrasheed, H. Ibrahim, Abdussamad Abubakar, H. Yakasai","doi":"10.54987/jobimb.v9i1.575","DOIUrl":"https://doi.org/10.54987/jobimb.v9i1.575","url":null,"abstract":"Azo dyes are the most common chemical family of dyes, with a wide range of structural and color variations. They account for up to 70% of yearly dye production. Azo dyes are one of the first man-made compounds, and they are still commonly used in the food and textile industries. The discharge of Azo dyes is undesirable not only because many Azo dyes and their breakdown products are toxic to aquatic life and mutagenic to people, but also because many Azo dyes and their breakdown products are harmful to aquatic life and mutagenic to humans. We report different primary kinetics models such as Huang, modified Gompertz, Buchanan-3-phase, modified Logistics, Baranyi-Roberts, modified Richards and Von Bertalanffy were used to get the best model for Candida tropicalis TL-F1 growth on different Azo dyes concentrations. The best model was found to be Buchanan-3-phase with the lowest values for AICc, RMSE and the highest value for adjusted R2. The AF and BF values were also excellent for the model with their values were the closest to 1.0. The poorest performance was found to be Baranyi-Roberts where it failed to model the growth curve. Baranyi-Roberts has the highest values for AICc, RMSE and the highest value for adjusted R2. The Buchanan-3-phase parameters such as Y0, Î», k and Ymax were found to be 0.290, 3.244, 0.543 and 3.825 respectively. These constant would provide insight for the actual Candida tropicalis TL-F1 growth curve.","PeriodicalId":15132,"journal":{"name":"Journal of Biochemistry, Microbiology and Biotechnology","volume":"78 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90236627","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 6

Association between ARID5B Polymorphisms and the Risk for Childhood B- Acute Lymphoblastic Leukaemia ARID5B多态性与儿童B-急性淋巴细胞白血病风险之间的关系

Journal of Biochemistry, Microbiology and Biotechnology Pub Date : 2021-07-29 DOI: 10.54987/jobimb.v9i1.568

C. Y. Ping, N. Abdullah, Nor Adzimah Johdi

{"title":"Association between ARID5B Polymorphisms and the Risk for Childhood B- Acute Lymphoblastic Leukaemia","authors":"C. Y. Ping, N. Abdullah, Nor Adzimah Johdi","doi":"10.54987/jobimb.v9i1.568","DOIUrl":"https://doi.org/10.54987/jobimb.v9i1.568","url":null,"abstract":"B-cell precursor acute lymphoblastic leukemia (B-ALL) is the commonest cancer in children, comprising over 80% of the entire childhood leukemia. However, the etiology of childhood B-ALL remains poorly understood and genetic susceptibility is a major risk factor for this disease. ARID5B appeared as one of the most promising genetic markers with nearly a 3-fold increased risk of disease. Method: In this meta-analysis, a total of six candidate ARID5B polymorphisms (i.e. rs10821936, rs10994982, rs7089424, rs10821938, rs10740055, and rs7073837) which have been analyzed in at least 2 studies were included for analysis of the risk association between ARID5B polymorphisms and childhood B-ALL. Results: Pooled analysis revealed that the dominant model of these six ARID5B polymorphisms was associated with an increased risk of childhood B-ALL. However, subgroup analysis based on ethnicity suggested that only four polymorphisms (i.e. rs10821936, rs10994982, rs7089424 and rs10821938) consistently conferred increased risk to childhood B-ALL across different populations, whereas the other 2 polymorphisms (rs10740055, rs7073837) were causative to Caucasians (OR=2.01, 95% CI=1.66-2.44; OR= 1.98, 95% CI=1.69-2.31) but maybe protective for Asian (OR=0.49, 95% CI=0.22-1.09; OR=0.95, 95% CI=0.43-2.09) respectively. Conclusion: Our meta-analysis demonstrated could serve as promising markers for assessing the susceptibility risk to childhood B-ALL in both the Asian and Caucasian populations. Further development of a multigene panel inclusive of ARID5B is desirable for screening children with a higher risk of developing B-ALL and to improve clinical management of the disease.","PeriodicalId":15132,"journal":{"name":"Journal of Biochemistry, Microbiology and Biotechnology","volume":"55 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79221581","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Enhancing Broilers Performance Fed Palm Kernel Expeller (PKE) Feeds Fortified with Supplements 添加添加物的棕榈仁膨化饲料提高肉鸡生产性能

Journal of Biochemistry, Microbiology and Biotechnology Pub Date : 2020-12-31 DOI: 10.54987/jobimb.v8i2.557

Muhamad Amin Jahari, M. Roslan, S. Mustafa, N. Abdullah, Z. Idrus

{"title":"Enhancing Broilers Performance Fed Palm Kernel Expeller (PKE) Feeds Fortified with Supplements","authors":"Muhamad Amin Jahari, M. Roslan, S. Mustafa, N. Abdullah, Z. Idrus","doi":"10.54987/jobimb.v8i2.557","DOIUrl":"https://doi.org/10.54987/jobimb.v8i2.557","url":null,"abstract":"Poultry production in Malaysia is heavily dependent on imported feed ingredients. There is a need to utilize local feed ingredients such as palm kernel expeller (PKE) to sustain poultry industry through physical treatments and so that it suitable to be incorporated into the feeds. Hence this study evaluates on the effects of control (0% PKE), untreated PKE (UPKE) , extruded PKE (EPKE), less-shell PKE (LSPKE) and extruded less-shell PKE (ELSPKE) at 10%, 20% and 30% inclusion rates in finisher diets (d 21-42) showed that growth performance of broilers (Cobb 500) fed 10% PKE, 20% LSPKE and ELSPKE, were comparable to control birds. At 30% PKE inclusion, broilers performance was significantly (P<0.05) reduced. Birds fed PKE diets, irrespective of treatments and inclusion levels had lower LDL and total cholesterol, and similar villi height and crypt depth compared to control. At 30% PKE inclusion level, although energy metabolism was enhanced, as indicated by the up-regulation of hexokinase I and phosphofructokinase, but broilers growth performance did not improve. The feeding trial showed that broilers fed 25% or 30% LSPKE (grower feed, d 16-24), followed by 20% LSPKE (finisher feed, d 25-35) containing feed supplements 0.02% commercial enzymes and 0.30% humic acid), had comparable FI, BWG and FCR to broilers fed commercial feeds. Broilers fed 25% or 30% UPKE (grower feed, d 16-24) followed by 20% UPKE (finisher feed, d 25-35) showed significantly higher (P<0.05) FCR compared to birds fed commercial feeds. The cost of feeds for production of birds fed LSPKE feeds (2.27-2.29 RM/kg liveweight), was lower than those fed commercial feeds (2.36 RM/kg liveweight). The study showed that physical treatments enhanced the nutritive value of PKE and feeds containing 25-30% and 20% LSPKE as grower and finisher rations, respectively, could attain broilers growth performance comparable to broilers fed commercial feeds.","PeriodicalId":15132,"journal":{"name":"Journal of Biochemistry, Microbiology and Biotechnology","volume":"15 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84809304","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1