Journal of Back and Musculoskeletal Rehabilitation最新文献

{"title":"The effects of progressive resistance training on lower limb strength in adolescents with cerebral palsy: A systematic review and meta-analysis.","authors":"Yu Fang, Weimin Zhang, Yang Zhang, Pengpeng Dong, Haolan Li, Sonthaya Sriramatr","doi":"10.1177/10538127261428185","DOIUrl":"https://doi.org/10.1177/10538127261428185","url":null,"abstract":"<p><p>BackgroundCerebral palsy (CP) is a leading cause of physical disability in children, characterized by impaired motor function and muscle weakness. Progressive resistance training (PRT) has emerged as a potential strategy for improving lower limb strength, though the existing evidence remains inconsistent.ObjectiveTo assess the impact of PRT on lower limb muscle strength in youth with CP, compared to control or alternative interventions.MethodsThis study systematically reviewed randomized controlled trials (RCTs) following PRISMA guidelines. Six RCTs involving 232 participants with CP (ages 8-25 years, GMFCS levels I-III) were included in the quantitative meta-analysis. Standardized mean differences (Hedges' g) were calculated using a random-effects model. Risk of bias was assessed using the Cochrane RoB 2 tool, and evidence certainty was evaluated using GRADE framework.ResultsPRT significantly improved lower limb muscle strength compared to controls (Hedges' g = 0.46, 95% CI [0.26-0.66], p < 0.001) with low-to-moderate heterogeneity (I² = 25.6%). Evidence certainty was rated as MODERATE. Subgroup analyses suggested potentially larger effects for gym-based interventions and participants with GMFCS II-III. Sensitivity analyses confirmed result robustness. No serious adverse events were reported.ConclusionPRT effectively enhances lower limb strength in youth (8-25 years) with CP, particularly under structured, supervised conditions. Further research is needed to clarify its long-term functional and psychosocial benefits.</p>","PeriodicalId":15129,"journal":{"name":"Journal of Back and Musculoskeletal Rehabilitation","volume":" ","pages":"10538127261428185"},"PeriodicalIF":1.4,"publicationDate":"2026-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147365358","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of remote myofascial manual therapy along the superficial back line on lumbo-pelvic-hip and neck flexibility and pain intensity: A systematic review and meta-analysis.","authors":"Long-Huei Lin, Nguyen Thi My Lien, Ilham Fatria, Yi-Chun Huang","doi":"10.1177/10538127261428186","DOIUrl":"https://doi.org/10.1177/10538127261428186","url":null,"abstract":"<p><p>BackgroundRemote myofascial manual therapy (RMFMT) is increasingly applied to improve flexibility and pain in musculoskeletal practice, yet evidence regarding its clinical efficacy remains inconclusive.ObjectiveThis meta-analysis evaluated the effectiveness of RMFMT applied along the superficial back line on flexibility and pain intensity.MethodsThis meta-analysis included randomized controlled trials (RCTs) on RMFMT retrieved from four databases (from inception to January 2026). A random-effects model was used to calculate pooled Hedges' g. Subgroup analyses were conducted according to assessment regions (or pain origins), intervention protocols, and control group types. In addition, the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) approach was applied to assess the certainty of evidence and inform the strength of clinical recommendations.ResultsNine RCTs (mean age: 20-40 years old; participants with pain-related symptoms and asymptomatic) demonstrated that RMFMT significantly improved flexibility (Hedges' <i>g</i> = 0.525, <i>p</i> < 0.001, <i>I²</i>= 49.014%), with favorable trends observed in both the cervical and lumbo-pelvic-hip regions, particularly when RMFMT was applied alone and compared to inactive control condition. Additionally, four RCTs suggested a borderline significant reduction in pain intensity (Hedges' g = -0.906, <i>p</i> = 0.070, <i>I²</i> = 87.420%) with similarly positive trends across both anatomical regions.ConclusionRMFMT applied along the superficial back line improved flexibility and showed a trend toward pain reduction compared with controls. Evidence certainty was moderate for flexibility and low for pain, supporting a conditional recommendation for RMFMT as an adjunctive intervention. Further high-quality RCTs are needed to strengthen the evidence.</p>","PeriodicalId":15129,"journal":{"name":"Journal of Back and Musculoskeletal Rehabilitation","volume":" ","pages":"10538127261428186"},"PeriodicalIF":1.4,"publicationDate":"2026-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147344358","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effect of Tai Chi on knee osteoarthritis: A systematic review and meta-analyses of 13 randomized controlled trials.","authors":"Yongying Liang, Yanming Guo, Shuailiang Zhou, Dehua Li, Jue Cen, Han Chen","doi":"10.1177/10538127261424311","DOIUrl":"https://doi.org/10.1177/10538127261424311","url":null,"abstract":"<p><p>Background and purposeOsteoarthritis is a public health issue in an aging society with no radical cure. Complementary therapies such as Tai Chi might be beneficial for patients with osteoarthritis.MethodsThe present meta-analysis summarized current evidence on the effectiveness of Tai Chi in patients with osteoarthritis. PubMed, Embase, and Cochrane Library databases were systematically searched for RCTs published from inception up to March 2020. The primary outcome was the pain score on the Western Ontario and McMaster Universities Arthritis Index (WOMAC). For pooled outcomes, standardized mean differences (SMDs) and 95% confidence intervals (CIs) were calculated.ResultsWe identified 13 trials with data from 817 patients. The results indicated that patients who practiced Tai Chi exercise showed more significant improvements in pain (SMD, -1.40; 95% CI, -2.17 to -0.63; P < 0.001), physical function (SMD, -1.54; 95% CI, -2.28 to -0.81; P < 0.001), and stiffness (SMD, -1.19; 95% CI, -1.94 to -0.44; P < 0.001) than the control group. Subgroup analysis data were consistent with the overall findings. Meta-regression showed that Tai Chi sessions, publication year, sample size, and Jadad score did not affect the therapeutic effects of Tai Chi. Tai Chi had a significant impact on the physiological and psychological health of patients with knee osteoarthritis.ConclusionsThis meta-analysis provides moderate-to-high quality evidence that Tai Chi has a clinically significant beneficial impact on knee osteoarthritis, with effect sizes exceeding minimal clinically important differences for pain and function.</p>","PeriodicalId":15129,"journal":{"name":"Journal of Back and Musculoskeletal Rehabilitation","volume":" ","pages":"10538127261424311"},"PeriodicalIF":1.4,"publicationDate":"2026-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147344326","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Somatosensory functions of ambulatory individuals with stroke related obviously with mobility without upper limb contribution.","authors":"Sugalya Amatachaya, Phouthasone Thavone, Wilairat Namwong, Thiwabhorn Thaweewannakij, Arpassanan Wiyanad, Pipatana Amatachaya","doi":"10.1177/10538127261428176","DOIUrl":"https://doi.org/10.1177/10538127261428176","url":null,"abstract":"<p><p>BackgroundThere is limited evidence regarding the proportion of somatosensory deficits and their contribution to mobility, particularly in relation to independence and safety among ambulatory individuals with stroke from a developing country.ObjectivesTo report the proportion of somatosensory deficits, and investigate the relationship between sensorimotor deficits and mobility outcomes among individuals with stroke who walked with or without a walking device.MethodsEighty participants, with an average age of approximately 60 years both male and female, were cross-sectionally assessed for their sensorimotor functions, and mobility using the 10-meter walk test, timed up and go test (TUG), five times sit-to-stand test (FTSST), and 6-min walk test. The Spearman's rank correlation coefficient (r_s) was used to analyze the correlation between sensorimotor and mobility outcomes.ResultsNearly 60% of the participants experienced somatosensory deficits (5 absent and 42 impaired sensation). A large proportion of these individuals walked with a walking device (42.6%). Mobility outcomes indicated that these participants walked non-functionally with high risk of fall and low functional endurance. The motor scores were strongly correlated with the TUG data (r_s = -0.719, p < 0.01), whereas the somatosensory scores were related predominantly to the FTSST data (r_s = -0.520, p < 0.01).ConclusionsSomatosensory impairments are common among ambulatory individuals with stroke. These impairments were primarily associated with mobility performed without hands. Therefore, rehabilitation strategies should target somatosensory alongside motor functions to enhance independence and safety, especially when therapeutic goals involve mobility without upper limb contribution.</p>","PeriodicalId":15129,"journal":{"name":"Journal of Back and Musculoskeletal Rehabilitation","volume":" ","pages":"10538127261428176"},"PeriodicalIF":1.4,"publicationDate":"2026-03-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147325992","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence of cervical spondylosis and associated factors among symptomatic adult patients at a tertiary hospital in Ethiopia 2023.","authors":"Beyan Abduljewad, Abay Mulu, Yared Mamushet, Biniyam Ayele","doi":"10.1177/10538127251388060","DOIUrl":"10.1177/10538127251388060","url":null,"abstract":"<p><p>BackgroundCervical spondylosis (CS) is an age related degenerative musculoskeletal condition that causes neck pain, radiculopathy, and myelopathy-associated paralysis.ObjectivesTo determine the prevalence of CS and identify associated risk factors among symptomatic adult patients.MethodsThis retrospective study was conducted at Tikur Anbessa Specialized Hospital between May and December 2022. Records of patients with spondylosis from January 2020 to January 2022 were reviewed. Inclusion criteria: confirmed CS with complete clinical and imaging data. Patients with incomplete records, acute trauma, or congenital, neoplastic, idiopathic, circulatory, or metabolic disorders were excluded.ResultsOf 2176 patients with spondylosis, 339 records were considered. Females accounted for 55.8% (<i>n</i> = 189), and males 44.2% (<i>n</i> = 150), with a mean age of 54.9 ± 10.04 years. Lumbar spondylosis was most prevalent (58.7%), followed by cervical (28.6%), combined cervical-lumbar (11.8%), and thoracic (0.9%). Multivariate analysis revealed higher CS risk among females (<i>p</i> = 0.003) and patients aged 40-59 years (<i>p</i> < 0.001). Smoking (AOR = 2.02) and alcohol consumption (<i>p</i> < 0.001) were also significant predictors.ConclusionCS prevalence in this study exceeded earlier reports. Risk increased with age, was greater among women, and was amplified by smoking and alcohol consumption.</p>","PeriodicalId":15129,"journal":{"name":"Journal of Back and Musculoskeletal Rehabilitation","volume":" ","pages":"608-618"},"PeriodicalIF":1.4,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145313009","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Validity of the Danish version of Multimorbidity Treatment Burden Questionnaire in patients with persistent spinal pain.","authors":"Jacob S Gandløse, Jonathan Vela, Thorvaldur S Palsson","doi":"10.1177/10538127251386968","DOIUrl":"10.1177/10538127251386968","url":null,"abstract":"<p><p>BackgroundPatients with persistent spinal pain often have comorbidities, increasing treatment burden. The Danish MTBQ-DK measures this burden, but its validity in this population is unknown.ObjectiveEvaluate the construct validity, internal consistency, convergent validity, and discriminative ability of the MTBQ-DK in patients with persistent spinal pain.MethodsPatients (n = 360) referred to the Department of Rheumatology, Aalborg University Hospital were included and completed self-report questionnaires, including the MTBQ-DK, PHQ-2, GAD-2, EQ-5D-5L (incl. EQ-VAS), and demographic items such as education and BMI. Clinical data were extracted from patient records, including ICD-10 diagnosis codes (used to determine number of chronic conditions and healthcare utilization) and use of pain medication. Construct validity was assessed using confirmatory factor analysis, and ordered logistic regression examined associations across treatment burden categories. Convergent validity, internal consistency and questionnaire properties were examined as well.ResultsA modified CFA supported the construct validity of the MTBQ-DK. In the ordered logistic regression, individuals with higher BMI (OR = 1.28, p = 0.02) and a greater number of ICD-10 diagnosis codes (OR = 1.07, p = 0.01) had significantly increased odds of being classified into a higher treatment burden category, compared to those with no reported treatment burden. Conversely, individuals not using pain medication had lower odds of being in a higher burden group (OR = 0.26, p < 0.01). These results indicate that the MTBQ-DK burden categories meaningfully differentiate between patient subgroups. Convergent validity showed fair correlations with PHQ-2 (ρ = 0.36), GAD-2 (ρ = 0.40), and chronic disease count (ρ = 0.28) (all p < 0.001). Negative correlations were found with EQ-5D-5L (ρ = -0.44) and EQ-VAS (ρ = -0.46) (both p < 0.001). Internal consistency was acceptable (Cronbach's α = 0.85). A floor effect ranged from 33.2% to 70.6%.ConclusionThe MTBQ-DK demonstrates acceptable validity for assessing treatment burden in patients with persistent spinal pain. Construct validity was supported by confirmatory factor analysis, internal consistency was acceptable, and convergent validity showed expected correlations. Ordered logistic regression confirmed meaningful differentiation between treatment burden groups, highlighting its potential as a tool to identify patients needing additional support.</p>","PeriodicalId":15129,"journal":{"name":"Journal of Back and Musculoskeletal Rehabilitation","volume":" ","pages":"576-585"},"PeriodicalIF":1.4,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145308135","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impairments of muscle strength, exercise capacity, and quality of life in patients with systemic sclerosis: A cross-sectional study.","authors":"Nihan Katayıfçı, Emine Özdil, İrem Hüzmeli, Bircan Yücekaya, Gezmiş Kimyon","doi":"10.1177/10538127251388061","DOIUrl":"10.1177/10538127251388061","url":null,"abstract":"<p><p>BackgroundFunctional capacity and muscle weakness are affected in patients with systemic sclerosis (SSc). However, upper extremity functional exercise capacity has not been sufficiently studied in patients with SScObjectiveThe primary objective was to compare upper extremity functional exercise capacity; secondary objectives were to compare functional exercise capacity, pulmonary function, respiratory muscle strength, balance, peripheral muscle strength, dyspnea, fatigue, quality of life (QoL), and physical activity in patients with SSc and healthy controls.MethodsTwenty-five patients and 25 healthy controls were included in this cross-sectional study. The upper extremity functional exercise capacity [6-min pegboard and ring test (6-PBRT)], functional exercise capacity [6-Minute Walking Test (6-MWT)], pulmonary function, respiratory muscle strength, balance, peripheral muscle strength, fatigue, dyspnea, QoL, and physical activity were assessed. Between-group comparisons used Student's t-test, the Mann-Whitney U test, or the Chi-square test as appropriate. Effect sizes (Cohen's d) were calculated for key outcomes.ResultsCompared to controls, patients with SSc had significantly lower 6-PBRT scores (Cohen's d = 3.29), 6-MWT distances (Cohen's d = 1.87), pulmonary function, respiratory and peripheral muscle strength, balance, QoL, and physical activity levels, with higher dyspnea and fatigue levels (p < 0.05).ConclusionsPatients exhibited impaired upper extremity functional exercise capacity, functional exercise capacity, pulmonary function, respiratory muscle strength, balance, peripheral muscle strength, QoL, and physical activity, as well as increased levels of dyspnea and fatigue compared to healthy controls. Therefore, after a comprehensive assessment including upper extremity functional exercise capacity, patients with SSc should be initiated into cardiopulmonary rehabilitation programs.</p>","PeriodicalId":15129,"journal":{"name":"Journal of Back and Musculoskeletal Rehabilitation","volume":" ","pages":"586-597"},"PeriodicalIF":1.4,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145336983","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Extracorporeal shock wave therapy versus Kinesio taping in treating musculoskeletal disorders: A GRADE-assessed systematic review and meta-analysis.","authors":"Mariam Hesham Sallam, Marwa Shafiek Mustafa Saleh, Haidy Samy, Mazen Mohamed Sayed, Hadel Hesham Elkhodary, Mariam Ismail Hassan, Esraa Mohamed Mosaid, Maryam Jalal Abdelrahman, Eman Mohamed Abdelwahab, Abdelrahman Fouad Elshafey, Abeer Gomaa Mohamed, Yasmin Ahmed Baioumy, Farah Tarek Hamouda, Bashayer Awad AlHarthy, Ahmed Ibrahim Abdelhamed","doi":"10.1177/10538127251384096","DOIUrl":"10.1177/10538127251384096","url":null,"abstract":"<p><p>BackgroundExtracorporeal shock wave therapy (ESWT) and Kinesio taping (KT) are used for musculoskeletal disorders (MSKDs). Despite limited supporting evidence and misalignment with contemporary rehabilitation approaches, they endure in practice to relieve pain and enhance function; however, their comparative effectiveness remains uncertain.ObjectivesThis systematic review aimed to compare the effects of ESWT versus KT on pain, functionality, strength, and quality of life (Qol) in individuals with MSKDs<b>.</b>MethodsSystematic searches of randomized clinical trials (RCTs) were performed across six databases from inception to June 2025. Two researchers independently screened titles, abstracts, and full-text articles. Risk of bias was assessed using the revised Cochrane Collaboration tool (RoB 2.0). Meta-analysis was conducted using RevMan 5.4 software, and the certainty of evidence was evaluated using the Grading of Recommendations, Assessment, Development, and Evaluation (GRADE) approach.ResultsFifteen RCTs (n = 907) were included. Comparative analysis revealed no statistically significant difference between ESWT and KT in improving pain 0.12 (95% CI: -0.17, 0. 41, p = 0.41), function 0.04 (95% CI: -0.43, 0.51; P = 0.86), strength 0.68 (95% CI: -7.46, 8.81; P = 0.87), or Qol (P >> 0.05) in the short-term. However, medium-term favored ESWT in pain -1.15 (95% CI: -1.52, -0.78, p < 0.00001) and function -0.89 (95% CI: -1.35, -0.42; P = 0.0002) over KT. The certainty of evidence for all outcomes was very low.ConclusionsVery low-quality evidence indicates no difference between ESWT and KT in improving pain, function, strength, and Qol in patients with MSKDs in the short-term, with a possible medium-term advantage for ESWT in improving pain and function. Our findings should be placed within the context of limited and geographically narrow evidence. High-quality, long-term RCTs are warranted.<b>Other:</b> No funding was received for this review. PROSPERO registration number (CRD42024559635).</p>","PeriodicalId":15129,"journal":{"name":"Journal of Back and Musculoskeletal Rehabilitation","volume":" ","pages":"410-422"},"PeriodicalIF":1.4,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145238614","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of upper and lower trapezius muscle strength in female office workers with and without chronic neck pain.","authors":"Alexandre Nunes, João Miguel, Kristian Kjær-Staal Petersen, Lars Arendt-Nielsen, Margarida Espanha","doi":"10.1177/10538127251380068","DOIUrl":"10.1177/10538127251380068","url":null,"abstract":"<p><p>BackgroundIn chronic pain patients, pain sensitivity and maximum voluntary contraction (MVC), a measure of muscle strength, are often impaired and related to the pain intensity. Therefore, this study aimed to assess MVC, pain sensitivity, and the potential association with pain intensity.MethodsA cross-sectional observational and analytic study with 133 female office workers was conducted, including both asymptomatic controls and those with chronic neck pain. The workers with chronic pain were categorized into pain conditions (chronic trapezius myalgia and chronic non-specific neck pain) and pain intensity groups, as mild pain (Visual analogue scale (VAS ≤ 3) and moderate pain (VAS > 3) groups. A handheld dynamometer was used to measure MVC at the upper trapezius (UT) and lower trapezius (LT). Pressure pain threshold (PPT) and temporal summation of pain (TSP) were assessed as measures of pain sensitivity.ResultsThe chronic trapezius myalgia group (n = 49) had a significantly decreased UT MVC [<i>F</i> (2128) = 4.099, <i>p</i> = 0.019] and LT MVC [<i>F</i> (2128) = 3.511, <i>p</i> = 0.033]. The moderate pain group (n = 43) had a significantly decreased UT MVC [<i>F</i> (2128) = 5.507, <i>p</i> = 0.005], and LT MVC [<i>F</i> (2128) = 4.119, <i>p</i> = .018]. Pain intensity, UT/LT ratio explained 19.4% of the variability in LT MVC, plus PPT explained 19.3% in UT MVC.ConclusionFemale office workers with CNP classified as moderate pain intensity and chronic trapezius myalgia had significantly decreased MVC in the UT and LT than the other groups. Pain intensity, decreased PPT in tibialis anterior, and the UT/LT ratio provide a limited explanation for muscle strength variability.</p>","PeriodicalId":15129,"journal":{"name":"Journal of Back and Musculoskeletal Rehabilitation","volume":" ","pages":"551-563"},"PeriodicalIF":1.4,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145206548","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ultrasound guided paravertebral ozone-oxygen injection versus pure oxygen for chronic discogenic low back pain: A double-blind randomized controlled trial.","authors":"Bijan Forogh, Kamyar Kazemi","doi":"10.1177/10538127251379512","DOIUrl":"10.1177/10538127251379512","url":null,"abstract":"<p><p>ObjectiveChronic discogenic low back pain (LBP) is one of the most prevalent musculoskeletal disorders. Despite numerous studies, the effectiveness of paraspinal ozone therapy continues to be uncertain, partly because of the methodological shortcomings. This study evaluates the effectiveness of para-spinal ozone-oxygen mixture injection compared to pure oxygen in chronic discogenic low back pain.DesignIn this double-blind RCT, 30 patients with MRI-confirmed chronic discogenic LBP were randomized into intervention (20 μg/mL ozone-oxygen mixture) or control (pure oxygen) groups. Every patient underwent a series of three ultrasound-guided para-spinal injections administered weekly in combination with exercise. Pain intensity (Visual Analog Scale, VAS) and functional status (Oswestry Disability Index, ODI) were assessed at baseline, one month, and three months post-intervention.ResultsBoth groups exhibited notable enhancements in VAS and ODI scores; however, the ozone group revealed more favorable results (P < 0.001). The ozone group exhibited significantly higher mean reductions in VAS (5.6 compared to 2.4) and ODI (19.07 compared to 7.8). (P < 0.001)ConclusionPara-spinal ozone-oxygen injection was significantly superior to pure oxygen in alleviating pain and enhancing functional scores. Despite limitations such as a small sample size, this research offers insights into ozone therapy as a promising minimally invasive alternative for chronic discogenic low back pain.</p>","PeriodicalId":15129,"journal":{"name":"Journal of Back and Musculoskeletal Rehabilitation","volume":" ","pages":"521-528"},"PeriodicalIF":1.4,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145124384","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}