Chinese Journal of Chemistry最新文献

{"title":"Inside Cover Picture","authors":"","doi":"10.1002/cjoc.70162","DOIUrl":"https://doi.org/10.1002/cjoc.70162","url":null,"abstract":"<p>With the idea of simple units integration to introduce new reactivities, a novel reaction between γ-hydroxyl enals and 1,3-dicarbonyl compounds has been discovered and developed, yielding polyfunctionalized 5-alkenyl-3-carbonylfurans. In this process, the γ-hydroxyl group is demonstrated to exert a critical neighboring group effect, facilitating the ring-opening isomerization of the initially generated 2<i>H</i>-pyran intermediate to the target furanones. More details are discussed in the article by Ma <i>et al</i>. on pages 1643—1650.\u0000\u0000 <figure>\u0000 <div><picture>\u0000 <source></source></picture><p></p>\u0000 </div>\u0000 </figure></p>","PeriodicalId":151,"journal":{"name":"Chinese Journal of Chemistry","volume":"43 14","pages":""},"PeriodicalIF":5.5,"publicationDate":"2025-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/cjoc.70162","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144292261","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Meet Our New Associate Editor","authors":"","doi":"10.1002/cjoc.70147","DOIUrl":"https://doi.org/10.1002/cjoc.70147","url":null,"abstract":"<p></p><p><b>Associate Editor</b></p><p><b>Wei Liu</b></p><p><b>Associate Professor</b></p><p><b>Department of Chemistry</b></p><p><b>University of Cincinnati, Cincinnati, Ohio, United States</b></p><p><b>(+1)513-556-5865</b></p><p><b>[email protected]</b></p><p><b>http://weiliulab.org</b></p><p>2004−2008 B. S. College of Chemistry and Molecular Engineering, Peking University (Supervisor: Prof. Gu Yuan)</p><p>2008−2014 Ph.D., Department of Chemistry, Princeton University (Supervisor: Prof. John T. Groves)</p><p>2017−2020 Assistant Professor, Department of Chemistry and Biochemistry, Miami University, Oxford, OH, USA</p><p>2020−2024 Assistant Professor, Department of Chemistry, University of Cincinnati, Cincinnati, OH, USA</p><p>2024−present Associate Professor, Department of Chemistry, University of Cincinnati, Cincinnati, OH, USA</p><p>2023 National Science Foundation CAREER award</p><p>2022 National Institute of Health Maximizing Investigators' Research Award</p><p>2022 American Chemical Society Herman Frasch Foundation Award</p><p>2022 Thieme Chemistry Journals Award</p><p><b>High-Valent Metal Catalysis</b></p><p>The ability of transition metals to reach high oxidation states, particularly among second- and third-row transition metals, has enabled the development of various catalytic transformations. However, the reactivity and catalytic potential of high-valent intermediates in earth abundant metals, especially first-row late transition metals, remain poorly understood. The research in the Liu group focuses on understanding of high-valent metal complexes to unlock new reactivity and address long-standing challenges in synthetic chemistry and biomedical research. To achieve these goals, we aim to <b>1)</b> understand the organometallics of elusive intermediates, <b>2)</b> develop new catalytic reactions and activation modes, and <b>3)</b> translate our chemistry to address unmet challenges in biomedical research.</p><p></p><p>1. <i>J. Am. Chem. Soc</i>. <b>2024</b>, <i>146</i>, 46, 31982–31991.</p><p>2. <i>J. Am. Chem. Soc</i>. <b>2024</b>, <i>146</i>, 43, 29297–29304.</p><p>3. <i>J. Am. Chem. Soc</i>. <b>2024</b>, <i>146</i>, 22, 15176–15185.</p><p>4. <i>Nature Catalysis</i> <b>2024</b>, <i>7</i>, 1372–1381.</p><p>5. <i>J. Am. Chem. Soc</i>. <b>2023</b>, <i>145</i>, 48, 26152–26159.</p>","PeriodicalId":151,"journal":{"name":"Chinese Journal of Chemistry","volume":"43 13","pages":""},"PeriodicalIF":5.5,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/cjoc.70147","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144190814","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Inside Cover Picture","authors":"","doi":"10.1002/cjoc.70139","DOIUrl":"https://doi.org/10.1002/cjoc.70139","url":null,"abstract":"<p>A series of regioselective [3+2] cycloaddition reactions between a potassium diazaphospholidinyl diazomethylide and unsaturated substrates are reported, enabling access to structurally diverse nitrogen-containing heterocycles. Depicted are robotic hands guiding the assembly of diazo anions and dipolarophiles to construct pyrazolide, triazolide, diazaphospholide, and pyrazolinide frameworks. This work, illustrated through an interplay of digital precision and molecular design, underscores the potential of electron-rich diazomethyl anions in click chemistry and heterocycle construction. More details can be found in the article by Liu <i>et al</i>. on pages 1547—1552.\u0000\u0000 <figure>\u0000 <div><picture>\u0000 <source></source></picture><p></p>\u0000 </div>\u0000 </figure></p>","PeriodicalId":151,"journal":{"name":"Chinese Journal of Chemistry","volume":"43 13","pages":""},"PeriodicalIF":5.5,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/cjoc.70139","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144190812","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Simple Units Integration Brings New Reactivity: Neighboring Group Effect in the Synthesis of Polyfunctionalized 5-Alkenyl-3-furanones from γ-Hydroxyl Enal","authors":"Jun Tan,&nbsp;Chengyan Xie,&nbsp;Youai Qiu,&nbsp;Dengke Ma","doi":"10.1002/cjoc.70032","DOIUrl":"https://doi.org/10.1002/cjoc.70032","url":null,"abstract":"<div>\u0000 \u0000 <p>With the hypothesis of simple units integration to create new reactivities, a strategy for the synthesis of polyfunctionalized 5-alkenyl-3-carbonylfurans from γ-hydroxyl enal and 1,3-dicarbonyl compounds is established, featuring readily available starting materials, high efficiency, good functional groups compatibility, green chemistry with high atom economy and only water release, <i>etc</i>., to provide a series of polyfunctionalized 5-alkenyl-3-carbonylfurans, which could be applied to the late-stage functionalization of naturally occurring compounds and bioactive molecules, as well as the transformation to pyrroles and polycyclic aromatic hydrocarbon via electrocyclic reaction. The γ-hydroxyl has played an important role in the unexpected process of ring opening isomerization of 2<i>H</i>-pyran to furanones, as confirmed by detailed mechanistic studies.</p>\u0000 <p>\u0000 </p>\u0000 </div>","PeriodicalId":151,"journal":{"name":"Chinese Journal of Chemistry","volume":"43 14","pages":"1643-1650"},"PeriodicalIF":5.5,"publicationDate":"2025-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144292852","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Inside Cover Picture","authors":"","doi":"10.1002/cjoc.70102","DOIUrl":"https://doi.org/10.1002/cjoc.70102","url":null,"abstract":"<p>Zeng <i>et al</i>. demonstrate various synthetic pathways for DNA coacervates based on liquid-liquid phase separation, exploring their biological and biomimetic applications. Benefiting from the programmability of DNA and the fluidity of coacervate structures, DNA coacervates can not only act as artificial cells with cell-like behaviors but also achieve intelligent sensing and precise therapy through specific signal transduction with natural cells. More details are discussed in the article on pages 1442—1462.\u0000\u0000 <figure>\u0000 <div><picture>\u0000 <source></source></picture><p></p>\u0000 </div>\u0000 </figure></p>","PeriodicalId":151,"journal":{"name":"Chinese Journal of Chemistry","volume":"43 12","pages":"1330"},"PeriodicalIF":5.5,"publicationDate":"2025-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/cjoc.70102","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144074464","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Chiral Hydrogen-Bonded Organic Frameworks: Design, Synthesis, and Applications†","authors":"Jialin Cui,&nbsp;Qingyan Pan,&nbsp;Xiaotao Wang,&nbsp;Hongbo Ma,&nbsp;Hailong Yu,&nbsp;Shiwei Liu,&nbsp;Yingjie Zhao","doi":"10.1002/cjoc.70042","DOIUrl":"https://doi.org/10.1002/cjoc.70042","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <p>Chiral framework materials, such as chiral metal-organic frameworks (MOFs) and chiral covalent organic frameworks (COFs), have been extensively reported and studied. However, research on chiral hydrogen-bonded organic frameworks (HOFs) is far behind. HOFs present a novel approach for creating chiral materials, thanks to their mild synthesis conditions, solution processability, and ease of repair and regeneration. This review provides a comprehensive overview of the design and synthesis strategies for chiral HOFs, highlighting recent advancements and exploring the applications of emerging chiral HOFs materials.</p>\u0000 \u0000 <p>\u0000 </p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Key Scientists</h3>\u0000 \u0000 <p>In the 1990s, Wuest and his collaborators advanced the development of the HOF field through the design and synthesis of porous hydrogen-bonded networks. In 2011, Chen and co-workers reported one of the first examples of microporous HOFs achieved through permanent porosity. In 2014, Ward and co-workers developed a series of two-dimensional guanidine-sulfonate hydrogen-bonded frameworks with tunable crystal structures, whose flexibility allowed them to be used for structural detection. Further, in 2015, Chen, Li and co-workers constructed the first example of chiral HOF derived from the chiral building block. In 2017, Yuan, Wu, and co-workers synthesized an ultrastable, easily regenerated hydrogen-bonded organic molecular framework with permanent porosity. In 2018, Cao, Liu and co-workers synthesized an ultrastable, crystalline, and recyclable HOF for synergistic chemo photodynamic therapy. In 2021, Zhang and co-workers achieved ethylene/ethane separation in a stable HOF through a gating mechanism. In 2022, Cao, Liu, and co-workers developed an innovative mechanochemical strategy for HOF synthesis. The story of HOFs is still unfolding.</p>\u0000 \u0000 <p>\u0000 </p>\u0000 </section>\u0000 </div>","PeriodicalId":151,"journal":{"name":"Chinese Journal of Chemistry","volume":"43 14","pages":"1756-1769"},"PeriodicalIF":5.5,"publicationDate":"2025-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144292198","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Inside Cover Picture","authors":"","doi":"10.1002/cjoc.70077","DOIUrl":"https://doi.org/10.1002/cjoc.70077","url":null,"abstract":"<p>Accurate prediction of chemical reaction performance is crucial for automated chemical synthesis. In this study, a novel multi-modal chemical reaction prediction model is proposed, using graph and textual information, eliminating the need for computationally intensive DFT parameters with capability to handling reactions involving a fluctuating number of molecules. This model outperforms at least 7 generalized methods on 4 datasets, while maintaining chemical interpretability towards atomic and feature importance. Further details are comprehensively discussed in the article by Li <i>et al</i>. on pages 1230—1238.\u0000\u0000 <figure>\u0000 <div><picture>\u0000 <source></source></picture><p></p>\u0000 </div>\u0000 </figure></p>","PeriodicalId":151,"journal":{"name":"Chinese Journal of Chemistry","volume":"43 11","pages":"1214"},"PeriodicalIF":5.5,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/cjoc.70077","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143897209","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Anomaly Detection Algorithm for Searching Selective Catalyst Differentiating Linear and Cyclic Alkanes in Oxidation","authors":"Jiaxing Liu,&nbsp;Pengkun Su,&nbsp;Bingling Dai,&nbsp;Da Zhou,&nbsp;Cheng Wang","doi":"10.1002/cjoc.70046","DOIUrl":"https://doi.org/10.1002/cjoc.70046","url":null,"abstract":"<div>\u0000 \u0000 <p>Selective catalysis, particularly when differentiating substrates with similar reactivities in a mixture, is a significant challenge. In this study, anomaly detection algorithms—tools traditionally used for identifying outliers in data cleaning—are applied to catalyst screening. We focus on developing catalytic methods to selectively oxidize cyclic alkanes over linear alkanes in mixtures such as naphtha. By inserting cyclohexane oxidation data one by one into a database of <i>n</i>-hexane oxidization, we used several anomaly detection algorithms to evaluate whether the inserted cyclohexane oxidation data could be considered anomalous. Conditions identified as anomalies imply that they are likely not suitable for <i>n</i>-hexane oxidization. As these anomalies come from conditions for cyclohexane oxidation, they are promising conditions for selective oxidation of cyclohexane while leaving <i>n</i>-hexane unaltered. These anomalies were thus further investigated, leading to the discovery of a specific catalytic approach that selectively oxidizes cyclohexane. This application of anomaly detection offers a novel method to search for selective catalyst for chemical reactions involving mixed substrates.</p>\u0000 <p>\u0000 </p>\u0000 </div>","PeriodicalId":151,"journal":{"name":"Chinese Journal of Chemistry","volume":"43 14","pages":"1685-1690"},"PeriodicalIF":5.5,"publicationDate":"2025-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144292735","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"In-Situ Exsolved Metal Nanoparticles for Solid Oxide Fuel Cell Anode: Mechanism, Design Strategies and Application","authors":"Xiongzhuang Li,&nbsp;Xinwei Su,&nbsp;Qiao Yuan,&nbsp;Mengting Wang,&nbsp;Wei Kong,&nbsp;Shanliang Chen,&nbsp;Petr Senin,&nbsp;Daifen Chen,&nbsp;Ting Chen,&nbsp;Tao Wei","doi":"10.1002/cjoc.70003","DOIUrl":"https://doi.org/10.1002/cjoc.70003","url":null,"abstract":"<div>\u0000 \u0000 <section>\u0000 \u0000 <h3> Comprehensive Summary</h3>\u0000 \u0000 <p>Solid oxide fuel cell (SOFC) is recognized as the third-generation fuel cell which transforms the chemical energy of different fuels directly into electrical energy with highly efficient. However, the sulfur poisoning and carbon deposition at high temperatures at the anode side hindered its commercialization. Using perovskite anodes combined with the <i>in-situ</i> exsolution (ISE) method has been extensively developed aimed at alleviating the above problems. This review is trying to depict a systematic overview of the mechanism of the ISE process, the strategies for designing ISE, and its application in SOFC anodes. We hope that this work could give a comprehensive understanding of future anodes for SOFC.</p>\u0000 \u0000 <p>\u0000 </p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Key Scientists</h3>\u0000 \u0000 <p>\u0000 </p>\u0000 </section>\u0000 </div>","PeriodicalId":151,"journal":{"name":"Chinese Journal of Chemistry","volume":"43 14","pages":"1707-1730"},"PeriodicalIF":5.5,"publicationDate":"2025-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144292755","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Silylative Kinetic Resolution of Acyclic Secondary Benzylic Alcohols Catalyzed by Chiral Guanidine Having Axial Chirality Containing a Methoxy Group","authors":"Yuki Homma,&nbsp;Takahisa Ikeue,&nbsp;Kenya Nakata","doi":"10.1002/cjoc.70025","DOIUrl":"https://doi.org/10.1002/cjoc.70025","url":null,"abstract":"<p>New chiral guanidine catalysts having axial chirality containing a methoxy group were synthesized. Subsequently, their catalytic ability was examined by applying the silylative kinetic resolution of racemic alcohols using chlorosilanes. Based on an X-ray crystallographic analysis of the catalysts, the functional role of the methoxy group was predicted, and the plausible reaction pathways and a transition state were described. It was also revealed that the existence of hydrogen bonding between the methoxy group on the catalyst and hydrogen atom at C-1 position of the substrates was of great importance for attaining high selectivity and reactivity. The proposed method is applicable to various acyclic aryl, heteroaryl, and normal-alkyl alcohols exhibiting medium to high <i>s</i>-values (<i>s</i> = 15–96, 15 examples).</p><p>\u0000 </p>","PeriodicalId":151,"journal":{"name":"Chinese Journal of Chemistry","volume":"43 13","pages":"1553-1559"},"PeriodicalIF":5.5,"publicationDate":"2025-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/cjoc.70025","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144191141","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}