Chinese Journal of Chemistry最新文献

{"title":"Inside Cover Picture","authors":"","doi":"10.1002/cjoc.202590042","DOIUrl":"https://doi.org/10.1002/cjoc.202590042","url":null,"abstract":"<p>Regioselective C3-nitration of indazoles is still challenging owing to the electron-deficient of C3-position. A variety of C3-nitroindazoles have been successfully prepared though TBN-mediated N—N bond formation with air and sequential 1,3-migration of nitro group. Moreover, the nitration reaction could be easily performed in the gram scales and applied in modifications of drugs at late-stage. More details are discussed in the article by Mo <i>et al</i>. on pages 393—398.\u0000\u0000 <figure>\u0000 <div><picture>\u0000 <source></source></picture><p></p>\u0000 </div>\u0000 </figure></p>","PeriodicalId":151,"journal":{"name":"Chinese Journal of Chemistry","volume":"43 4","pages":"362"},"PeriodicalIF":5.5,"publicationDate":"2025-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/cjoc.202590042","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143115227","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Total Syntheses of Highly Oxidized Natural Products†","authors":"Yan Wang,&nbsp;Xiangbing Qi","doi":"10.1002/cjoc.202400898","DOIUrl":"https://doi.org/10.1002/cjoc.202400898","url":null,"abstract":"&lt;div&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Comprehensive Summary&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;Natural products with high oxidation states and complex chemical skeletons exhibit diverse bioactivities due to their unique interactions with biological targets. The high oxidation state is characterized by the presence of multiple oxygen-containing functional groups such as hydroxyl groups, carbonyl groups, and epoxides that are usually tough to construct selectively. In recent years, thanks to the development of efficient strategies and sophisticated methodologies, significant advancements have been made in the total syntheses of highly oxidized natural products (HONPs). In this review, we highlight recent examples of HONPs focusing on tetrodotoxin (TTX) and its derivatives, steroidal alkaloids, sesquiterpenes, and diterpenoids since 2019.&lt;/p&gt;\u0000 \u0000 &lt;p&gt;\u0000 &lt;/p&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Key Scientists&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;In 2005, the Yang group applied the thioureas as ligands in the Pauson−Khand reaction for total synthesis of triterpene natural products. The methodological advances have achieved total syntheses of a series of topologically complex natural products with diverse structural features in the following years. In 2009, the Baran group established a pioneering “two-phase” approach for the total synthesis of highly oxidized terpenes, an innovative strategy has since inspired numerous advancements in the field. In 2011, Xu and Theodorakis achieved the total synthesis of (−)-jiadifenolide, a highly oxidized sesquiterpene from &lt;i&gt;Illicium&lt;/i&gt;. In 2012, the Li group applied 6π electrocyclization for total synthesis of natural products containing aromatic rings. In 2014, the Inoue group introduced the α-alkoxy bridgehead radical, facilitating a unified total synthesis of ryanodane diterpenoids. In subsequent years, radical-based convergent strategies were employed for assembling HONPs. The Li group developed the type ΙΙ [5+2] reaction, which can be efficiently applied in the total synthesis of HONPs featuring bridged ring systems. The Reisman group presented the oxidation pattern analysis that guided their synthetic designs for the synthesis of complex, highly oxidized ryanodane and isoryanodane diterpenes. In 2017, the Gao group reported a photoenolization/Diels-Alder (PEDA) reaction for constructing related polycyclic rings with elevated oxidation states. In 2018, the Ding group developed an unprecedented oxidative dearomatization-induced (ODI) [5+2] cycloaddition/pinacol- type 1,2-acyl migration cascade to assemble the highly oxygenated bicyclo[3.2.1]octane ring system, which was subsequently applied to the synthesis of highly oxidized grayanane diterpenoids. In the same year, the Gui group explored “bioinspired” strategic transformations that enabled the rapid construction of core framework of steroid and terpenoid nat","PeriodicalId":151,"journal":{"name":"Chinese Journal of Chemistry","volume":"43 6","pages":"650-714"},"PeriodicalIF":5.5,"publicationDate":"2025-01-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143423570","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Stereoselective Synthesis of 2-Deoxy Glycosides via a Novel 2-O-Resided (o-Alkynyl)benzoate-Initiated 1,2-Sulfur Migration/Glycosylation and Desulfurization Protocol as well as Mechanism Elucidation","authors":"Jin-Xi Liao,&nbsp;Zhen-Qiang Li,&nbsp;Yanli Qiu,&nbsp;Xiang-Yang Gao,&nbsp;Xin Lv,&nbsp;Hui Liu,&nbsp;Yuan-Hong Tu,&nbsp;Jian-Song Sun","doi":"10.1002/cjoc.202401198","DOIUrl":"https://doi.org/10.1002/cjoc.202401198","url":null,"abstract":"<div>\u0000 \u0000 <p>Stereoselective construction of 2-deoxy-glycosidic linkages has been achieved by the 1,2-sulfur migration/glycosylation and desulfurization strategy; however, current protocols suffer from harsh reaction conditions and unsatisfactory stereoselectivity, particularly during the 1,2-<i>S</i>-migration/glycosylation step. With 2-<i>O</i>-resided (<i>o</i>-alkynyl)benzoate and anomeric <i>p</i>-methoxyphenylsulfenyl groups as the initiating and migrating groups, respectively, a novel protocol for the efficient synthesis of 2-deoxy-glycosides via the 1,2-sulfur migration/glycosylation-desulfurization strategy has been established, which is featured by the mild and catalytic reaction conditions, expanded substrate scope, as well as good to excellent diastereoselectivity. Mechanism studies determined hyperconjugation-stabilized oxocarbenium ion as the key intermediate, achieving high 1,2-<i>trans</i> stereocontrol through thermodynamic, steric, as well as electrostatic effects. This provides the fresh insight for the operative mechanism of the 1,2-sulfur migration/glycosylation and desulfurization strategy, further corroborated by the elaborately designed testing reactions and DFT calculations. Moreover, the synthetic potential of the newly established protocol was examined by the practical synthesis of natural product, culminating in the acquisition of digoxin from acetylated digoxigenin in 25% overall yield through an 8-step longest linear sequence.</p>\u0000 <p>\u0000 </p>\u0000 </div>","PeriodicalId":151,"journal":{"name":"Chinese Journal of Chemistry","volume":"43 7","pages":"783-790"},"PeriodicalIF":5.5,"publicationDate":"2025-01-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143521796","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Inside Cover Picture","authors":"","doi":"10.1002/cjoc.202590032","DOIUrl":"https://doi.org/10.1002/cjoc.202590032","url":null,"abstract":"<p><i>gem</i>-Difluoroalkenes are highly regarded for their use as fluorinated synthetic building blocks and are also recognized for their numerous applications in the pharmaceuticals. A practical zinc-mediated approach for the synthesis of 3-<i>gem</i>-difluorovinyl lactams through a sequential reductive hydrodehalogenation has been disclosed. Additionally, such a strategy could also enable the generation of the high value-added vicinal dideuterated <i>gem</i>-difluoroalkenes with excellent deuterium (D) incorporation at both <i>α- and β</i>-positions with the presence of inexpensive deuterium oxide. More details are discussed in the article by Hu <i>et al</i>. on pages 255—260.\u0000\u0000 <figure>\u0000 <div><picture>\u0000 <source></source></picture><p></p>\u0000 </div>\u0000 </figure></p>","PeriodicalId":151,"journal":{"name":"Chinese Journal of Chemistry","volume":"43 3","pages":"246"},"PeriodicalIF":5.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/cjoc.202590032","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143110240","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Catalytic Difunctionalization of Alkenes under Visible Light Irradiation: Synthesis of Iminofuranones","authors":"Boyu Liu,&nbsp;Guangxian Chen,&nbsp;Lele Zhang,&nbsp;Feiwei Yan,&nbsp;Feiming Li,&nbsp;Zhixiong Cai,&nbsp;Mingqiang Huang,&nbsp;Lina Cai,&nbsp;Shunyou Cai","doi":"10.1002/cjoc.202401116","DOIUrl":"https://doi.org/10.1002/cjoc.202401116","url":null,"abstract":"<div>\u0000 \u0000 <p>Here, we show a cost-effective and environmentally friendly method for synthesizing iminofuranones using visible light and the photocatalyst 2-bromoanthraquinone. Our approach uses only oxygen as the oxidant, avoiding the need for additional transition metals and strong oxidizing agents. By employing a mixed solvent system of DMF and CHCl₃ under ambient conditions, we have achieved highly diastereoselective conversions of various 2-vinyl benzamides and alkenyl amides into functionalized iminoisobenzofuranones and iminofuranones. This versatile process is broadly applicable and enables late-stage structural modifications of complex substrates with bioactive moieties.</p>\u0000 <p>\u0000 </p>\u0000 </div>","PeriodicalId":151,"journal":{"name":"Chinese Journal of Chemistry","volume":"43 7","pages":"798-804"},"PeriodicalIF":5.5,"publicationDate":"2024-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143521852","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Storage Failure Mechanisms and Modifications of Ni-Rich Cathode Materials: From Polycrystalline to Single-Crystal Forms†","authors":"Ran An,&nbsp;Yuefeng Su,&nbsp;Chenxing Yang,&nbsp;Xinyu Zhu,&nbsp;Yihong Wang,&nbsp;Yongjian Li,&nbsp;Lai Chen,&nbsp;Yun Lu,&nbsp;Qing Huang,&nbsp;Meng Wang,&nbsp;Ning Li,&nbsp;Feng Wu","doi":"10.1002/cjoc.202400806","DOIUrl":"https://doi.org/10.1002/cjoc.202400806","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <p>Ni-rich cathode materials, exemplified by LiNi_{1–<i>x</i>–<i>y</i>}Co_<i>x</i>MnyO₂ (NCM), have significantly propelled Li-ion battery (LIB) technology forward owing to their high energy density. However, the long-term storage stability of these materials remains a critical challenge that must be addressed. This review provides a comprehensive analysis of the storage failure mechanisms in both polycrystalline (PC-NCM) and single crystal (SC-NCM) forms, a topic that has been seldom reviewed. It delves into the microstructural changes and performance degradation that occur during storage, emphasizing the effects of environmental factors on NCM materials, including the formation of surface impurities and structural deterioration. Additionally, the review discusses various enhancement strategies, such as surface coatings, doping, and gas treatments, which are designed to improve storage stability. Furthermore, the review projects insights from current polycrystalline studies to suggest future research directions aimed at enhancing the air stability of SC-NCM, which is vital for improving the safety and durability of LIBs.</p>\u0000 \u0000 <p></p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Key Scientists</h3>\u0000 \u0000 <p>\u0000 \u0000 </p>\u0000 </section>\u0000 </div>","PeriodicalId":151,"journal":{"name":"Chinese Journal of Chemistry","volume":"43 7","pages":"823-840"},"PeriodicalIF":5.5,"publicationDate":"2024-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143521853","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bioinspired Coordination for Fabricating Self-healing and Injectable Hydrogels with Antibacterial and Immunoregulatory Activities†","authors":"Youlu Diao,&nbsp;Jia Gao,&nbsp;Xinrui Li,&nbsp;Miao Wang,&nbsp;Guoqing Pan","doi":"10.1002/cjoc.202401108","DOIUrl":"https://doi.org/10.1002/cjoc.202401108","url":null,"abstract":"<div>\u0000 \u0000 <p>Inspired by the molecular mechanism of mussel adhesion, here, we developed a class of injectable and self-healing hydrogels based on natural polysaccharide hyaluronic acid (HA). The dynamic property of hydrogels is derived from histidine-metal coordination, which widely exists in the mussel adhesive plaque. To mimic components of mussel byssal threads, we first grafted histidine-containing peptides onto the HA chains. Followed by the addition of Zn²⁺ ions, the modified HA could then transform into a pH-sensitive hydrogel network (HA-His-Zn) with tunable sol-gel transitions. The dynamic metal-ligand coordination could significantly enhance the mechanical properties of HA hydrogels and also endow them with self-healing and injectable abilities. In addition, the HA-His-Zn hydrogels could also exhibit antibacterial and immunoregulatory activities due to the bioactive Zn²⁺ ions. These results, together with the dynamic properties and good biocompatibility, indicated that the HA-His-Zn hydrogels could be applied as a class of easy-to-handle scaffold materials for regeneration medicine, particularly for tissue traumas with chronic inflammations and infections.</p>\u0000 <p>\u0000 </p>\u0000 </div>","PeriodicalId":151,"journal":{"name":"Chinese Journal of Chemistry","volume":"43 7","pages":"775-782"},"PeriodicalIF":5.5,"publicationDate":"2024-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143521855","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assembly of Homochiral Titanium-Oxo Clusters Protected by in situ Generated Chiral Ligands for Enhanced Photoelectrochemical Activity","authors":"Nahui Huang,&nbsp;Jinle Hou,&nbsp;Ye Wang,&nbsp;Pengfei Fei,&nbsp;Dongxu Zhang,&nbsp;Zhi Wang,&nbsp;Konggang Qu,&nbsp;Xianxi Zhang,&nbsp;Di Sun","doi":"10.1002/cjoc.202401117","DOIUrl":"https://doi.org/10.1002/cjoc.202401117","url":null,"abstract":"<div>\u0000 \u0000 <p>The synthesis of titanium oxo clusters (TOCs) with both chirality and photoactivity is urgently needed to expand their applications. However, this remains a significant challenge due to synthetic difficulties and limitations in chiral ligand selection. In this work, we have isolated two pairs of enantiomeric TOCs, [Ti₃(μ₃-O)(<i>R/S</i>-L1)₂(ⁱPrO)₆] (<b><i>R</i>/<i>S-</i>Ti3</b>; ^<i>i</i>PrOH = isopropanol, <i>R</i>/<i>S</i>-L1 = <i>R</i>/<i>S</i>-2'-hydroxy-[1,1'- binaphthalen]-2-yl isopropyl hydrogenphosphate) and [Ti₄(μ₂-O)(μ₄-O)(<i>R</i>/<i>S</i>-L2)₂(EtO)₈] (<b><i>R</i>/<i>S</i>-Ti4</b>; EtOH = ethanol, <i>R</i>/<i>S</i>-L2 = <i>R</i>/<i>S</i>-2'-hydroxy-[1,1'-binaphthalen]-2-yl ethyl hydrogenphosphate), via an <i>in situ</i> ligand transformation approach. The <i>R</i>/<i>S</i>-L1 and <i>R</i>/<i>S</i>-L2 ligands were obtained by alcoholysis of <i>R</i>/<i>S</i>-L (<i>R</i>/<i>S</i>-1,1'-binaphthyl-2,2'-diyl hydrogenphosphate) in different reaction solvents. These ligands, with additional coordination sites, facilitated the formation of novel TOCs and improved their stability. Importantly, these clusters exhibited exceptional stability in solid state and maintained appreciable stability in solution. Furthermore, the introduction of chiral ligands not only imparts a homochiral nature to <b><i>R</i>/<i>S</i>-Ti3</b> and <b><i>R</i>/<i>S</i>-Ti4</b> but also confers upon them superior photoelectric properties due to ligand-to-metal charge transfer (LMCT) phenomena, as confirmed by theoretical calculations. This study offers a valuable synthetic strategy for preparing photoactive chiral TOCs, and we anticipate it will inspire new discoveries in the field of chiral metal nanoclusters.</p>\u0000 <p>\u0000 </p>\u0000 </div>","PeriodicalId":151,"journal":{"name":"Chinese Journal of Chemistry","volume":"43 7","pages":"750-758"},"PeriodicalIF":5.5,"publicationDate":"2024-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143521854","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Recent Progress of Artificial Cilia: From Bioinspired Design, Facile Fabrication to Practical Application†","authors":"Yingbo Li,&nbsp;Ran Zhao,&nbsp;Jingxin Meng","doi":"10.1002/cjoc.202401006","DOIUrl":"https://doi.org/10.1002/cjoc.202401006","url":null,"abstract":"&lt;div&gt;\u0000 \u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;p&gt;As well known, cilia play an irreplaceable role in sensing and movement of natural organisms because they can respond to external signals and generate net flow in complex environments. Based on these findings, scientists further explored the functions of natural cilia and have developed many artificial cilia in the past nearly thirty years. This review provides an overview of recent progress of artificial cilia. Firstly, we summarize the characteristics of natural cilia. Subsequently, we introduce the fabrication methods including template, magnetic assembly, lithography, and 3D printing. Then we discuss the stimulus actuation of artificial cilia from two major modes: contact control and remote control. In addition, five typical types of applications, including adhesion regulation, intelligent control, mobile microrobot, biological sensor and anti-counterfeiting, were reviewed in detail. Finally, we present the challenges and future development in the fields of advanced artificial cilia.&lt;/p&gt;\u0000 \u0000 &lt;p&gt;&lt;/p&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Key Scientists&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;From 1994 to 1997, research teams including Bohringer, Donald, and Macdonald from Cornell University and Suh and Kovacs from Stanford University reported on the application of artificial cilia in the field of micro-electro-mechanical systems (MEMS) technology,&lt;sup&gt;[1-3]&lt;/sup&gt; while Fujita from the University of Tokyo and Stemme from KTH were also conducting research in artificial cilia fields at the same time. In 2006, Krijnen's team designed a combination of cricket cerci cilia and MEMS technology to further extend the application of artificial cilia to flow sensors.&lt;sup&gt;[4]&lt;/sup&gt; In 2007, Superfine's crew introduced the polycarbonate track-etched (PCTE) membrane method into the fabrication of artificial cilia, achieving the fabrication of high aspect ratio cilia in a liquid free environment.&lt;sup&gt;[5]&lt;/sup&gt; Since 2008, Toonder's lab has been focusing on the research of artificial cilia and have made outstanding contributions in lab on chip and achieve various stimuli responsive actuation of artificial cilia.&lt;sup&gt;[6-8]&lt;/sup&gt; In 2010, Alexeev's research team used computer simulations to design a hydrodynamic model of ciliary strike.&lt;sup&gt;[9]&lt;/sup&gt; Since 2017, Jiang and his coworkers have made progress in the application of directional manipulation of artificial cilia, including research on solids, droplets and bubbles.&lt;sup&gt;[10-13]&lt;/sup&gt; In 2020—2024, Sitti's research group has introduced cilia into the field of bioinspired microrobot and realized the programmed actuation of artificial cilia from the perspectives of electricity, photothermal and magnetic.&lt;sup&gt;[14-19]&lt;/sup&gt; In 2022, Jeong's group innovated the traditional magnetic assembly method to fabricate three-dimensional nanoscale cilia with regular spatial distribution and co","PeriodicalId":151,"journal":{"name":"Chinese Journal of Chemistry","volume":"43 7","pages":"841-854"},"PeriodicalIF":5.5,"publicationDate":"2024-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143521851","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Boosting Covalent Organic Framework Luminescence by Suppressing Nonradiative Pathways†","authors":"Minghao Liu,&nbsp;Yuan-Zhe Cheng,&nbsp;Yubin Fu,&nbsp;Shuai Bi,&nbsp;Xuesong Ding,&nbsp;Bao-Hang Han,&nbsp;Qing Xu,&nbsp;Gaofeng Zeng","doi":"10.1002/cjoc.202400986","DOIUrl":"https://doi.org/10.1002/cjoc.202400986","url":null,"abstract":"<div>\u0000 \u0000 <p>The construction of luminescent two-dimensional (2D) imine-linked covalent organic frameworks (COFs) is a formidable challenge due to the strong interlayer stacking and bond rotations that typically suppress intramolecular charge transfer (ICT), leading to nonradiative energy dissipation. Herein, three COFs with tailored interlayer distances and bond rotations are designed to modulate the ICT behaviours. The targeted COF (TPAZ-TPE-COF) achieved a significantly enhanced photoluminescence quantum yield (PLQY) of 21.22% in the solid state by restricting bond rotation and enlarging the layer distance. This represents a 3.5-fold and 530.5-fold improvement over TPAZ-PYTA-COF (6.15%), which has a shortened interlayer space, and TPAZ-PATA-COF (0.04%), which exhibits strong bond rotations, respectively. Importantly, TPAZ-TPE-COF also exhibits exceptional sensing performance for iron ions, with a detection limit at the ppb level. Both experimental and theoretical analyses reveal that the prominent luminescent performance of TPAZ-TPE-COF is assigned to the effective suppression of nonradiative pathways, especially those arising from interlayer stacking and bond vibrations. These findings pave the way for deliberate construction of imine-linked 2D COFs with high PL intensity, thereby expanding the portfolio of luminescent COFs with potential applications in sensing and optoelectronics.</p>\u0000 <p>\u0000 </p>\u0000 </div>","PeriodicalId":151,"journal":{"name":"Chinese Journal of Chemistry","volume":"43 6","pages":"633-640"},"PeriodicalIF":5.5,"publicationDate":"2024-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143424318","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}