Inside Cover Picture

Abstract

A series of regioselective [3+2] cycloaddition reactions between a potassium diazaphospholidinyl diazomethylide and unsaturated substrates are reported, enabling access to structurally diverse nitrogen-containing heterocycles. Depicted are robotic hands guiding the assembly of diazo anions and dipolarophiles to construct pyrazolide, triazolide, diazaphospholide, and pyrazolinide frameworks. This work, illustrated through an interplay of digital precision and molecular design, underscores the potential of electron-rich diazomethyl anions in click chemistry and heterocycle construction. More details can be found in the article by Liu et al. on pages 1547—1552.