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Identification of Quinolones/Fluoroquinolones Resistance Genes from Staphylococci Strains Isolated at the University Hospital of Brazzaville, Republic of the Congo 刚果共和国布拉柴维尔大学医院葡萄球菌喹诺酮类/氟喹诺酮类耐药基因的鉴定
Journal of Biosciences and Medicines Pub Date : 2023-01-01 DOI: 10.4236/jbm.2023.112003
Léa Gwladys Gangoue, Faust René Okamba Ondzia, S. A. Nzaou, Fils Landry Mpele, Tarcisse Baloki Ngoulou, Fabien Rock Niama, R. Moyen, Etienne Nguimbi
{"title":"Identification of Quinolones/Fluoroquinolones Resistance Genes from Staphylococci Strains Isolated at the University Hospital of Brazzaville, Republic of the Congo","authors":"Léa Gwladys Gangoue, Faust René Okamba Ondzia, S. A. Nzaou, Fils Landry Mpele, Tarcisse Baloki Ngoulou, Fabien Rock Niama, R. Moyen, Etienne Nguimbi","doi":"10.4236/jbm.2023.112003","DOIUrl":"https://doi.org/10.4236/jbm.2023.112003","url":null,"abstract":"","PeriodicalId":15067,"journal":{"name":"Journal of Biosciences and Medicines","volume":"25 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81642065","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Content Determination of Vitamin C in Durian Endocarp and Optimization of Extraction Process 榴莲内果皮中维生素C含量测定及提取工艺优化
Journal of Biosciences and Medicines Pub Date : 2023-01-01 DOI: 10.4236/jbm.2023.118016
Chenxi Xin, Jiuying Cui, Zichun Song, Yan Li
{"title":"Content Determination of Vitamin C in Durian Endocarp and Optimization of Extraction Process","authors":"Chenxi Xin, Jiuying Cui, Zichun Song, Yan Li","doi":"10.4236/jbm.2023.118016","DOIUrl":"https://doi.org/10.4236/jbm.2023.118016","url":null,"abstract":"Purpose: To optimize the extraction process of vitamin C from durian endo-carp, and to determine the content of vitamin C in durian endocarp with high performance liquid chromatography (HPLC). Method: Optimize ultrasonic extraction conditions by L9 (4 3 ) orthogonal experiment by using octadecylsi-lane chemically bonded silica as the stationary phase, using methanol (A): 0.1% oxalic acid (B) = 5:95 (V/V) as the mobile phase, setting the flow rate as 1.0 mL/min, and setting the wavelength as 254 nm for assay. Result: The optimal extraction process is as follows: the material-liquid ratio is 1:12, the extraction solvent is 2% oxalic acid aqueous solution, and the extraction time is 30 min; Vitamin C has a good linearity within the concentration range of 5.4 - 108.0 mg·mL −1 , and the regression equation is y = 37698x − 61035 (R 2 = 0.9996); the average recovery rate is 99.03%, the instruments are of high precision with good stability. Conclusion: This extraction process performs well in simplicity, costs and extraction efficiency, which may accelerate the development and utilization of vitamin C extraction from durian endocarp, and provide references to relevant studies and practices.","PeriodicalId":15067,"journal":{"name":"Journal of Biosciences and Medicines","volume":"135 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73338980","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Situational Analysis of Malaria Control Following the 2021 Distribution of Long Lasting Insecticide-Treated Bed Nets in the Tiko Health District, South West Region, Cameroon 2021年在喀麦隆西南地区Tiko卫生区分发长效驱虫蚊帐后疟疾控制情况分析
Journal of Biosciences and Medicines Pub Date : 2023-01-01 DOI: 10.4236/jbm.2023.114011
Jini Victor Bongajum, Nyasa Raymond Babila, E. M. Eyong
{"title":"Situational Analysis of Malaria Control Following the 2021 Distribution of Long Lasting Insecticide-Treated Bed Nets in the Tiko Health District, South West Region, Cameroon","authors":"Jini Victor Bongajum, Nyasa Raymond Babila, E. M. Eyong","doi":"10.4236/jbm.2023.114011","DOIUrl":"https://doi.org/10.4236/jbm.2023.114011","url":null,"abstract":"","PeriodicalId":15067,"journal":{"name":"Journal of Biosciences and Medicines","volume":"3 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75492168","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Case of Target Immunotherapy Combined with Interventional Therapy for Massive Liver Cancer 靶向免疫联合介入治疗肝癌1例
Journal of Biosciences and Medicines Pub Date : 2023-01-01 DOI: 10.4236/jbm.2023.112016
Ruidong Zhao, Xiangli Zheng
{"title":"A Case of Target Immunotherapy Combined with Interventional Therapy for Massive Liver Cancer","authors":"Ruidong Zhao, Xiangli Zheng","doi":"10.4236/jbm.2023.112016","DOIUrl":"https://doi.org/10.4236/jbm.2023.112016","url":null,"abstract":"","PeriodicalId":15067,"journal":{"name":"Journal of Biosciences and Medicines","volume":"16 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80149856","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Tuberculosis Infected T Lymphocyte Spot as a Differential Diagnosis of Pulmonary Tuberculosis and Choriocarcinoma Recurrence: A Case Report and Review of the Literature 结核感染T淋巴细胞斑点作为肺结核和绒毛膜癌复发的鉴别诊断:1例报告及文献复习
Journal of Biosciences and Medicines Pub Date : 2023-01-01 DOI: 10.4236/jbm.2023.119004
Qi Wu, Zhaoping Chu, J. Dai, L-G Jia, Xinling Wang, Lihui Li, Jie Li, Yuan Zhang, Ping Yan, Jia-qi Hou
{"title":"Tuberculosis Infected T Lymphocyte Spot as a Differential Diagnosis of Pulmonary Tuberculosis and Choriocarcinoma Recurrence: A Case Report and Review of the Literature","authors":"Qi Wu, Zhaoping Chu, J. Dai, L-G Jia, Xinling Wang, Lihui Li, Jie Li, Yuan Zhang, Ping Yan, Jia-qi Hou","doi":"10.4236/jbm.2023.119004","DOIUrl":"https://doi.org/10.4236/jbm.2023.119004","url":null,"abstract":"","PeriodicalId":15067,"journal":{"name":"Journal of Biosciences and Medicines","volume":"6 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74299677","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Recent Advances in HIV-Associated Neurocognitive Disorders hiv相关神经认知障碍的最新进展
Journal of Biosciences and Medicines Pub Date : 2023-01-01 DOI: 10.4236/jbm.2023.119013
Qianqian Tang, Hao Wu, Maogong Tang
{"title":"Recent Advances in HIV-Associated Neurocognitive Disorders","authors":"Qianqian Tang, Hao Wu, Maogong Tang","doi":"10.4236/jbm.2023.119013","DOIUrl":"https://doi.org/10.4236/jbm.2023.119013","url":null,"abstract":"HIV-associated neurocognitive disorders (HAND) are chronic complications of HIV infection in the central nervous system. Clinical presentations include asymptomatic neurocognitive impairment (ANI), mild neurocognitive impairment (MND), and HIV-associated dementia (HAD). In the era of combination antiretroviral therapy (cART), the prevalence of HAD has significantly decreased, but the rates of ANI and MND have increased, impairing patients’ daily functioning, medical adherence, employment, driving abilities, risk of HIV transmission, overall quality of life, and posing challenges to society, economy, families, and public health. This article reviews the latest research findings regarding the pathogenesis, clinical diagnosis and treatment, neuroimaging, and neuropsychological assessment of HAND, aiming to provide insights into the prevention and management of HAND.","PeriodicalId":15067,"journal":{"name":"Journal of Biosciences and Medicines","volume":"33 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135494948","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
HealthNet: Machine Learning for Cystic Fibrosis Characterization 健康网:囊性纤维化表征的机器学习
Journal of Biosciences and Medicines Pub Date : 2023-01-01 DOI: 10.4236/jbm.2023.119014
Manasvi Pinnaka, Eric Cheek
{"title":"HealthNet: Machine Learning for Cystic Fibrosis Characterization","authors":"Manasvi Pinnaka, Eric Cheek","doi":"10.4236/jbm.2023.119014","DOIUrl":"https://doi.org/10.4236/jbm.2023.119014","url":null,"abstract":"Cystic fibrosis patients often develop lung infections because of the presence of thick and sticky mucus that fills their airways. The presence of this thick mucus prevents the lungs from filtering out certain dominant bacterial types, making patients highly susceptible to infections that can range anywhere in severity from mild to life-threatening. These infections can cause great distress for patients as it becomes harder for patients to breathe and increases the chance of mortality by respiratory failure. It is important to be able to track the progression or regression of cystic fibrosis to determine the best course of treatment. Thus, this project focuses on the use of an AI model to examine the microbiology of cystic fibrosis patients and predict the condition or stage of lung function in the future, as a way to guide doctors with their treatment plan. Due to the limited amounts of publicly available patient data, we used all of the data in the training and testing of our machine learning algorithms initially and then tried a 50% training, 10% validation, and 40% testing split. Our results show that with relatively simple models (cubic polynomials), we can predict FEV1 from statistically significant bacteria sequences within 98% accuracy when training on sufficiently large samples.","PeriodicalId":15067,"journal":{"name":"Journal of Biosciences and Medicines","volume":"75 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135556155","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Mechanism and Research Progress of Ferroptosis in Esophageal Squamous Cell Carcinoma 食管鳞状细胞癌中铁下垂的机制及研究进展
Journal of Biosciences and Medicines Pub Date : 2023-01-01 DOI: 10.4236/jbm.2023.1110022
Jinmeng Gong, Xiaoping Tan
{"title":"The Mechanism and Research Progress of Ferroptosis in Esophageal Squamous Cell Carcinoma","authors":"Jinmeng Gong, Xiaoping Tan","doi":"10.4236/jbm.2023.1110022","DOIUrl":"https://doi.org/10.4236/jbm.2023.1110022","url":null,"abstract":"Esophageal squamous cell carcinoma (ESCC), as the main histological type of esophageal cancer (EC), has the characteristics of high malignant degree, high mortality and tendency to lymph node metastasis. Despite the combination of surgery and chemoradiotherapy, ECSS has a poor prognosis. Ferroptosis is a newly discovered iron-dependent programmed cell death pattern characterized by the accumulation of lipid peroxidation and characteristic morphological changes of mitochondria. It regulates the growth and invasion of cancer cells in various tumors such as gastric cancer and pancreatic cancer. In this article, we mainly introduce the ferroptosis regulatory mechanism in ESCC, hoping to provide a new direction and ideas for the treatment of ECSS.","PeriodicalId":15067,"journal":{"name":"Journal of Biosciences and Medicines","volume":"16 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135211196","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Research Progress of Pyroptosis in Ophthalmic Diseases 眼病热下垂的研究进展
Journal of Biosciences and Medicines Pub Date : 2023-01-01 DOI: 10.4236/jbm.2023.114012
Yuan-Qi Jiang, Xuelei Zhang, Xiaoqin Wang
{"title":"Research Progress of Pyroptosis in Ophthalmic Diseases","authors":"Yuan-Qi Jiang, Xuelei Zhang, Xiaoqin Wang","doi":"10.4236/jbm.2023.114012","DOIUrl":"https://doi.org/10.4236/jbm.2023.114012","url":null,"abstract":"","PeriodicalId":15067,"journal":{"name":"Journal of Biosciences and Medicines","volume":"51 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86828765","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Anti-Fibrotic Effects of Calotropis procera (Ait.) R.Br Roots Barks against Diethylnitrosamine-Induced Hepatic Fibrosis in Rats 原心热疣的抗纤维化作用根茎对二乙基亚硝胺所致大鼠肝纤维化的影响
Journal of Biosciences and Medicines Pub Date : 2023-01-01 DOI: 10.4236/jbm.2023.114024
Ernest Nogma Sombié, Tata Kadiatou Traoré, A. Derra, J. N’do, W. Belem-Kabré, N. Ouedraogo, A. Hilou, A. Tibiri
{"title":"Anti-Fibrotic Effects of <i>Calotropis procera</i> (Ait.) R.Br Roots Barks against Diethylnitrosamine-Induced Hepatic Fibrosis in Rats","authors":"Ernest Nogma Sombié, Tata Kadiatou Traoré, A. Derra, J. N’do, W. Belem-Kabré, N. Ouedraogo, A. Hilou, A. Tibiri","doi":"10.4236/jbm.2023.114024","DOIUrl":"https://doi.org/10.4236/jbm.2023.114024","url":null,"abstract":"","PeriodicalId":15067,"journal":{"name":"Journal of Biosciences and Medicines","volume":"39 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87567364","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
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