Felipe P Perez, Maryam Rahmani, Jorge Morisaki, Farhan Amran, Syazwani Bakri, Akmal Halim, Alston Dsouza, Nurafifi Mohd Yusuff, Amran Farhan, James Maulucci, Maher Rizkalla
{"title":"Numerical Modeling and Computer Simulation of a Meander Line Antenna for Alzheimer's Disease Treatment, a Feasibility Study.","authors":"Felipe P Perez, Maryam Rahmani, Jorge Morisaki, Farhan Amran, Syazwani Bakri, Akmal Halim, Alston Dsouza, Nurafifi Mohd Yusuff, Amran Farhan, James Maulucci, Maher Rizkalla","doi":"10.4236/jbm.2023.112013","DOIUrl":"https://doi.org/10.4236/jbm.2023.112013","url":null,"abstract":"<p><p>Alzheimer's disease (AD) is a brain disorder that eventually causes memory loss and the ability to perform simple cognitive functions; research efforts within pharmaceuticals and other medical treatments have minimal impact on the disease. Our preliminary biological studies showed that Repeated Electromagnetic Field Stimulation (REFMS) applying an EM frequency of 64 MHz and a specific absorption rate (SAR) of 0.4 - 0.9 W/kg decrease the level of amyloid-<i>β</i> peptides (A<i>β</i>), which is the most likely etiology of AD. This study emphasizes uniform E/H field and SAR distribution with adequate penetration depth penetration through multiple human head layers driven with low input power for safety treatments. In this work, we performed numerical modeling and computer simulations of a portable Meander Line antenna (MLA) to achieve the required EMF parameters to treat AD. The MLA device features a low cost, small size, wide bandwidth, and the ability to integrate into a portable system. This study utilized a High-Frequency Simulation System (HFSS) in the design of the MLA with the desired characteristics suited for AD treatment in humans. The team designed a 24-turn antenna with a 60 cm length and 25 cm width and achieved the required resonant frequency of 64 MHz. Here we used two numerical human head phantoms to test the antenna, the MIDA and spherical head phantom with six and seven tissue layers, respectively. The antenna was fed from a 50-Watt input source to obtain the SAR of 0.6 W/kg requirement in the center of the simulated brain tissue layer. We found that the E/H field and SAR distribution produced was not homogeneous; there were areas of high SAR values close to the antenna transmitter, also areas of low SAR value far away from the antenna. This paper details the antenna parameters, the scattering parameters response, the efficiency response, and the E and H field distribution; we presented the computer simulation results and discussed future work for a practical model.</p>","PeriodicalId":15067,"journal":{"name":"Journal of Biosciences and Medicines","volume":"11 2","pages":"177-185"},"PeriodicalIF":0.0,"publicationDate":"2023-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10026125/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9187534","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yasir I. B. Ahmed, Hind S. Yagoub, Mohamed A. Hassan
{"title":"Maternal <i>TMPRSS6</i> Gene Polymorphism rs855791SNP in Women with Preeclampsia","authors":"Yasir I. B. Ahmed, Hind S. Yagoub, Mohamed A. Hassan","doi":"10.4236/jbm.2023.111008","DOIUrl":"https://doi.org/10.4236/jbm.2023.111008","url":null,"abstract":"","PeriodicalId":15067,"journal":{"name":"Journal of Biosciences and Medicines","volume":"96 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74783222","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Advances on the Treatment of Allergic Rhinitis by Traditional Chinese Medicine and Western Medicine","authors":"Wenjing Lu","doi":"10.4236/jbm.2023.114010","DOIUrl":"https://doi.org/10.4236/jbm.2023.114010","url":null,"abstract":"","PeriodicalId":15067,"journal":{"name":"Journal of Biosciences and Medicines","volume":"41 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78218732","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Adriana Préfina Nzoumba Pandi, S. Mokémiabeka, J. Bidounga, Tarcisse Baloki Ngoulou, R. Moyen
{"title":"Evaluation of the Bioremediation Potential and Antimicrobial Activity of <i>Pseudomonas</i> and Bacillus Bacteria Isolated from Landfills in Brazzaville, Congo","authors":"Adriana Préfina Nzoumba Pandi, S. Mokémiabeka, J. Bidounga, Tarcisse Baloki Ngoulou, R. Moyen","doi":"10.4236/jbm.2023.118011","DOIUrl":"https://doi.org/10.4236/jbm.2023.118011","url":null,"abstract":"","PeriodicalId":15067,"journal":{"name":"Journal of Biosciences and Medicines","volume":"7 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81734717","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Analysis of Human Papillomavirus Infection in Cervical Exfoliated Cells","authors":"Yuan Xu, Qi Wen, Zheng Zhao, Ke Zhang, Shuying Li","doi":"10.4236/jbm.2023.118017","DOIUrl":"https://doi.org/10.4236/jbm.2023.118017","url":null,"abstract":"","PeriodicalId":15067,"journal":{"name":"Journal of Biosciences and Medicines","volume":"375 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85468177","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dhornycia Euroldyne Malaissou Tony, R. Ampa, Abraham Mayoke, R. P. Boukongo, H. M. Mambeke, Berthrand Stéphane Lingomo Wossolo, M. Diatewa
{"title":"Effect of <i>Tetracera potatoria</i> Aqueous Extract on Mellitus Diabetes and Its Complication Preventions in Wistar Rats","authors":"Dhornycia Euroldyne Malaissou Tony, R. Ampa, Abraham Mayoke, R. P. Boukongo, H. M. Mambeke, Berthrand Stéphane Lingomo Wossolo, M. Diatewa","doi":"10.4236/jbm.2023.117016","DOIUrl":"https://doi.org/10.4236/jbm.2023.117016","url":null,"abstract":"","PeriodicalId":15067,"journal":{"name":"Journal of Biosciences and Medicines","volume":"55 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72808007","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Idriss Ntatou Lemouchele, Suzi Pascale Mbougang, E. Bell, L. Foko, Eric Fouelifack Nzeko, C. O. Ebongue, Jean Pierre Nda Mefo’o, Martin Luther Koanga Mogtomo, Rosalie Annie Ngono Ngane
{"title":"Profiling and Determinants of Impaired Lipid Profile Parameters among Breast Cancer Women of Childbearing Age Living in Douala, Cameroon","authors":"Idriss Ntatou Lemouchele, Suzi Pascale Mbougang, E. Bell, L. Foko, Eric Fouelifack Nzeko, C. O. Ebongue, Jean Pierre Nda Mefo’o, Martin Luther Koanga Mogtomo, Rosalie Annie Ngono Ngane","doi":"10.4236/jbm.2023.115014","DOIUrl":"https://doi.org/10.4236/jbm.2023.115014","url":null,"abstract":"","PeriodicalId":15067,"journal":{"name":"Journal of Biosciences and Medicines","volume":"42 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82528542","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Forson, Seth Adu-Adjei, M. Olu-Taiwo, B. Mensah, A. Martin-Odoom
{"title":"Occurrence of <i>Salmonella</i> Enteric Serovar Typhi Antibodies among Blood Donors in Ghana","authors":"A. Forson, Seth Adu-Adjei, M. Olu-Taiwo, B. Mensah, A. Martin-Odoom","doi":"10.4236/jbm.2023.113018","DOIUrl":"https://doi.org/10.4236/jbm.2023.113018","url":null,"abstract":"","PeriodicalId":15067,"journal":{"name":"Journal of Biosciences and Medicines","volume":"41 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87020474","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Brahima Bamba, Seydou Silué, Tiémélé Eugène Atayi, A. Tako
{"title":"Effects of Ovariectomy and 17<i>β</i>-Estradiol Replacement on the Activity of Dopamine D2 Receptors in the Selection of Macronutrients Carbohydrates, Lipids and Proteins in Females Rats","authors":"Brahima Bamba, Seydou Silué, Tiémélé Eugène Atayi, A. Tako","doi":"10.4236/jbm.2023.115006","DOIUrl":"https://doi.org/10.4236/jbm.2023.115006","url":null,"abstract":"","PeriodicalId":15067,"journal":{"name":"Journal of Biosciences and Medicines","volume":"61 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87086399","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}