Journal of Anatomy最新文献

{"title":"Issue Cover (September 2026)","authors":"","doi":"10.1111/joa.70218","DOIUrl":"https://doi.org/10.1111/joa.70218","url":null,"abstract":"<p>Cover image: How the brain helps to reveal the position of the sulci on the endocast (drawing by Tiphaine Derrey). See\u0000A. Balzeau et al., ‘The “Rosetta Stone” of Paleoneurology: A detailed study of the link between the brain and the\u0000endocast on 75 volunteers’, this issue.</p><p>\u0000 \u0000 <figure>\u0000 <div><picture>\u0000 <source></source></picture><p></p>\u0000 </div>\u0000 </figure>\u0000 </p>","PeriodicalId":14971,"journal":{"name":"Journal of Anatomy","volume":"249 3","pages":""},"PeriodicalIF":2.2,"publicationDate":"2026-08-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/joa.70218","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148662187","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Issue Cover (September 2026)","authors":"","doi":"10.1111/joa.70218","DOIUrl":"https://doi.org/10.1111/joa.70218","url":null,"abstract":"<p>Cover image: How the brain helps to reveal the position of the sulci on the endocast (drawing by Tiphaine Derrey). See\u0000A. Balzeau et al., ‘The “Rosetta Stone” of Paleoneurology: A detailed study of the link between the brain and the\u0000endocast on 75 volunteers’, this issue.</p><p>\u0000 \u0000 <figure>\u0000 <div><picture>\u0000 <source></source></picture><p></p>\u0000 </div>\u0000 </figure>\u0000 </p>","PeriodicalId":14971,"journal":{"name":"Journal of Anatomy","volume":"249 3","pages":""},"PeriodicalIF":2.2,"publicationDate":"2026-08-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/joa.70218","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148662418","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of arterial and venous variations in thorax computed tomography examinations","authors":"Mine Işık Tanış,&nbsp;İsmail Nadir Gülekon,&nbsp;Şilan Işık","doi":"10.1111/joa.70108","DOIUrl":"10.1111/joa.70108","url":null,"abstract":"<p>Vascular variations may be found incidentally during radiological imaging and may not cause any symptoms throughout life. This study was carried out to determine the incidence and clinical significance of normal, variable and abnormal branching patterns of thoracic vascular structures in the general adult population using computed tomography (CT) images. Thorax CT images of 1510 patients (716 males and 794 females) aged between 18 and 95 years were reviewed for this purpose. One hundred and eighty-four (12.2%) patients had bovine arch variation in which the brachiocephalic trunk and the left common carotid artery originated from a common source. In 57 (3.8%) of the examined cases, the left vertebral artery was observed to directly originate from the aortic arch. Additionally, in 14 (0.9%) patients, the right subclavian artery was found to arise directly from the aortic arch. The accessory hemiazygos vein drained into the left brachiocephalic vein in 329 (21.8%) patients, and the right internal thoracic vein opened into the superior vena cava in 29 (1.9%) patients. Azygos vein variation was detected in 18 (1.2%) patients among the examined 1510 patients. Among 1510 patients analysed, double superior vena cava was found in one female patient, and situs inversus totalis was found in two female patients. Knowledge about these variations is important during interventional procedures. CT is a non-invasive imaging modality that offers a comprehensive assessment of these variations.</p>","PeriodicalId":14971,"journal":{"name":"Journal of Anatomy","volume":"249 3","pages":"578-586"},"PeriodicalIF":2.2,"publicationDate":"2026-08-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145998238","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Spatiotemporal remodelling of the cloacal region determines the position of the anal opening in mouse embryos","authors":"Weiyi Wang,&nbsp;Masayo Harada,&nbsp;Keiichi Akita","doi":"10.1111/joa.70110","DOIUrl":"10.1111/joa.70110","url":null,"abstract":"<p>Conventional embryological models propose that the urorectal septum (URS) fuses with the cloacal membrane (CM) to form separate exits for the hindgut and urogenital sinus (UGS). However, previous studies have been re-evaluating this assumption, and the precise morphogenetic mechanisms determining the position of the anal opening remain unclear. To elucidate the spatial and temporal dynamics of cloacal development, we analysed mouse embryos from embryonic day (E)11.5 to E13.5 using serial midsagittal histological sections combined with three-dimensional reconstruction. We focused on the positional relationship between the URS and CM, as well as the internal remodelling events of the cloaca that lead to anal opening formation. Throughout development, the URS enlarged and shifted distally, but consistently remained dorsodistal to the CM without direct fusion. At E13.0, we identified an expanded space at the caudal end of the hindgut, distinct from the hindgut lumen. By E13.25, this space connected to the UGS via a duct-like structure, contributing to the separation of the UGS and hindgut. By E13.5, the CM ruptured and the anal opening emerged precisely at the junction between the hindgut lumen and the expanded space. Our findings demonstrate that the position of the anal opening is predetermined by cloacal internal space remodelling rather than fusion of the URS and CM. This study offers novel insights into normal anorectal development and the aetiology of congenital anorectal malformations.</p>","PeriodicalId":14971,"journal":{"name":"Journal of Anatomy","volume":"249 3","pages":"652-658"},"PeriodicalIF":2.2,"publicationDate":"2026-08-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13399002/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146105576","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Syrinx anatomy and vocalizations in New World vultures (Aves: Cathartidae): Implications for avian vocal evolution.","authors":"Bradley A Ibarra, Carmen A Urban, Lucas J Legendre, Julia A Clarke","doi":"10.1111/joa.70217","DOIUrl":"10.1111/joa.70217","url":null,"abstract":"<p><p>New World vultures (Cathartidae) are the only birds proposed to lack a syrinx, the avian vocal organ. The prior literature is inconsistent regarding the presence or lack of key syringeal elements in Cathartidae, such as syringeal muscles, membranes, and/or modified tracheal or bronchial rings. Additionally, New World vultures have largely been described as incapable of producing vocalizations, perhaps due to their described lack of a functional syrinx; despite this, there is a diverse repertoire of sounds made by species within Cathartidae available in online sound libraries. Here, we investigate the cathartid syrinx, airway, and larynx through dissections, diffusible iodine-based contrast enhanced computed tomography (diceCT), and histology. We further assess available recordings and explore the potential identity of these as larynx- or syrinx-based vocalizations. New World vultures indeed lack labia, bronchial half-rings, and marked differentiation of the tracheobronchial juncture, challenging simple definitions of a syrinx. However, they retain extrinsic syringeal muscles, have modified terminal bronchial rings, extended bronchial membranes, and muscles from the thoracic wall extending to these bronchial membranes unknown in any other birds, all of which may be involved in sound production. This evidence, in conjunction with the variety of vocalization types produced, indicates that cathartid vultures may in fact have a novel form of the syrinx. These findings have implications for broadening our understanding of the necessary components of a syrinx and provide insights into the loss and addition of syringeal elements in Aves. Assessing syrinx diversity is essential to understanding form-function relationships in Aves and the evolution of vocal behavior.</p>","PeriodicalId":14971,"journal":{"name":"Journal of Anatomy","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2026-07-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13408219/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148603309","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Widespread complex enameloid microstructure in teeth and rostral denticles of Cretaceous sclerorhynchoid skates (Rajiformes: †Sclerorhynchoidei).","authors":"Endy Chateauneuf-Gautier, Guillaume Guinot","doi":"10.1111/joa.70215","DOIUrl":"10.1111/joa.70215","url":null,"abstract":"&lt;p&gt;&lt;p&gt;Enameloid is a type of hard mineralised tissue covering teeth and dermal denticles of extant and extinct chondrichthyans. Understanding the diversity of enameloid microstructures across chondrichthyan clades is key to highlight potential phylogenetic or adaptive signals provided by histological characters. Among chondrichthyans, the enameloid microstructure of teeth and odontodes of batomorphs (skates and rays) has been understudied despite the high extant and past taxonomic and morphological diversities of this clade. Here, we focus on the sclerorhynchoid rays, a speciose extinct (Cretaceous) clade of skates that developed rostra bearing enlarged denticles in most taxa. We explore the enameloid microstructure of both teeth and rostral denticles of 13 species representing a wide range of morphologies. Our results show that the tooth enameloid microstructure of sclerorhynchoid skates achieved a complex arrangement, with a high diversity of bundled components. This microstructure is furthermore complexified by a strong degree of apico-basal variation in the organisation of the enameloid components. This organisation is the most complex known so far among batomorph teeth and probably elasmobranchs in general. Our results further confirm the presence of a similarly complex enameloid microstructure in the dermal denticles covering the elongated rostrum of these extinct skates. Most importantly, we provide evidence for the pervasiveness of this complex enameloid across rostral denticles of all studied taxa, despite the wide range of taxa and morphologies represented. The common enameloid organisation reported in both teeth and rostral denticles is, from base to the apex: a Single-Crystallite Enameloid (SCE) layer passing into Radial Bundled Enameloid (RBE) sometimes through a phase of protobundles as the enameloid thickens slightly higher in the crown, with apico-basal Parallel-Bundled Enameloid (PBE) appearing mixed with RBE bundles higher up at the base of the cusp, followed by the classical three-layered enameloid including SCE, PBE and Tangled-Bundled Enameloid (TBE) in the apex, crossed by rare Thick Radial Bundles (TRB). The presence of protobundles and RBE forming the entire enameloid thickness in the basalmost crown enameloid of teeth and rostral denticles analysed here was so far restricted to placoid scales and teeth of some hybodonts and batomorphs. Our study identified protobundles as transitional organisation between SCE and structured bundles and the RBE as an organisational stage preceding the PBE. We demonstrate that TRB are isolated RBE bundles and that both RBE and PBE bundles can participate in circumferential bundles whose development is linked with the size of the cutting edges. We found no evidence for a clear phylogenetic signal provided by the distribution of enameloid microstructure characters neither within teeth, nor among rostral denticles sampled here. Instead, we propose a possible link with geometric constraints (he","PeriodicalId":14971,"journal":{"name":"Journal of Anatomy","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2026-07-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13408005/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148603218","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Multiscale analysis of the adult human superior hypogastric plexus and hypogastric nerve.","authors":"Kayleigh S Scotcher, John-Paul Fuller-Jackson, Peregrine B Osborne, Martin M Bertrand, Janet R Keast","doi":"10.1111/joa.70213","DOIUrl":"10.1111/joa.70213","url":null,"abstract":"<p><p>The superior hypogastric plexus (SHP) and hypogastric nerves (HN) are components of the autonomic nervous system required for sympathetic regulation of the pelvic viscera. Despite their functional importance, the three-dimensional (3D) distribution and immunohistochemical composition of neurons in these structures remain poorly characterized. In this study, we used a multiscale imaging approach to generate a 3D anatomical and immunohistochemical characterization of the SHP and HN in adult humans. Both embalmed (body donor program) and unembalmed paraformaldehyde (PFA)-fixed specimens (organ donor program) were cleared using a modified Adipo-Clear/iDISCO protocol and imaged by light sheet fluorescence microscopy. Thousands of neuronal cell bodies were identified within the HN, demonstrating that this nerve does not function solely as a conduit for axons. In one HN sample analyzed along its whole length by immunohistochemistry, more than 90% of the neurons were tyrosine hydroxylase-immunoreactive (TH-IR), so presumed to be noradrenergic. Neuronal cell bodies in both the SHP and HN were arranged in clusters of diverse size, embedded within nerve tracts rather than in discrete ganglia. High-resolution confocal microscopy of cryosections confirmed the presence of numerous TH-IR (presumed noradrenergic) neuronal cell bodies and axons in the SHP and HN. Non-noradrenergic axonal populations were also abundant. Putative afferent axons (calcitonin gene-related peptide- and substance P-immunoreactive) traversed the SHP and HN and occasionally encircled individual ganglion neurons, raising the possibility of direct sensory-motor communication at these sites. Collectively, these findings provide a new 3D anatomical and immunohistochemical characterization of the SHP and HN in the adult human. This has important implications for understanding normal pelvic autonomic function and pathophysiology of genitourinary disorders. These data and further application of our imaging approach will inform the improvement of nerve-sparing surgical techniques in the pelvic region and the development of targeted neuromodulation approaches.</p>","PeriodicalId":14971,"journal":{"name":"Journal of Anatomy","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2026-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13396685/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148578451","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The ovary structure and oogenesis in Hydrachnidia (Acariformes: Parasitengona).","authors":"Anna Derdak, Joanna Mąkol, Karol Małota, Izabela Jędrzejowska","doi":"10.1111/joa.70214","DOIUrl":"10.1111/joa.70214","url":null,"abstract":"<p><p>Although our understanding of ovary structure in mites is limited, it has been shown that the female gonads in these arachnids are highly diverse compared with other chelicerates. Unlike other chelicerates, which typically have a panoistic ovary with a relatively consistent architecture, mites also possess a meroistic ovary. In the panoistic ovary, germline cells differentiate into oocytes, whereas in the meroistic ovary, the germline cells differentiate into oocytes and their accompanying nurse cells. Both types of ovaries have been observed in the two mite lineages, Acariformes and Parasitiformes. Hydrachnidia (Acariformes), also known as water mites, are one of the largest groups of freshwater arthropods. However, despite their common occurrence, they are less explored compared with freshwater insects and crustaceans. Data on the structure of the ovary in water mites are scarce and originate from the 20 c. The aim of the study is to analyze the ovary structure of adult females representing five families of water mites: Arrenuridae, Hydrachnidae, Hydrodromidae, Pionidae, and Limnesiidae, using light, fluorescence, and transmission electron microscopy. Serial block-face scanning electron microscopy technique was applied for 3D reconstruction of the germline cysts. Our results provide new data on the structure of the ovary in water mites, challenging earlier literature data on the panoistic ovary in this group. In all species examined, the presence of a meroistic ovary has been confirmed. The ovary contains a number of germline cysts composed of several germline cells diversified into one oocyte and a few nurse cells. Within the cysts, each cell (oocyte and nurse cells) is connected by a cytoplasmic bridge to a central cytoplasm. The oocytes start previtellogenesis and protrude on the ovary surface connected to the latter by long oocyte stalks. The nurse cells remain in the ovary wall; their nuclei are highly branched and polyploid. The nurse cells provide macromolecules and organelles to oocytes transferred by trophic cords in a microtubular-dependent manner. The results of our study indicate that the overall architecture of the ovary, the structure of the germline cysts, the pattern of germline cell differentiation, and the trophic support remain consistent across Hydrachnidia.</p>","PeriodicalId":14971,"journal":{"name":"Journal of Anatomy","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2026-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13399028/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148520562","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Flying whales: Insights into the flipper of the humpback whale and its relatives using a novel tissue-illuminating technique.","authors":"Romain Cottereau, Georg Hantke, Andrew C Kitchener","doi":"10.1111/joa.70211","DOIUrl":"10.1111/joa.70211","url":null,"abstract":"<p><p>Cetaceans primarily generate thrust through dorsoventral oscillations of the caudal flukes, while their flippers are generally associated with lift generation and torque production during manoeuvring. However, the humpback whale, which possesses the largest forelimbs among extant and extinct vertebrates, has been observed performing active flipper strokes that contribute to forward propulsion. This behaviour represents a unique combination of axial swimming and underwater flight among cetaceans. In this study we investigate the anatomical correlates of this rarely observed locomotor behaviour and examine how the distinctive flipper anatomy of the humpback whale compares to that of other cetaceans. We focus in particular on the musculoskeletal and tendinous organisation of the flipper. We compared the flipper musculoskeletal anatomy of the humpback whale with that of seven other cetacean species (two mysticetes and five odontocetes). A novel protocol to acquire images during dissections involving ultraviolet (UV) light was employed to enhance the contrast between skeletal elements, musculature and connective tissues, with a particular emphasis on tendons and entheses. Although all flippers are highly vascularised, antebrachial musculature is strongly reduced across cetaceans, a condition that is especially pronounced in humpback whales and several odontocete lineages that lack antebrachial muscles. These findings suggest that active control of the flipper is primarily achieved proximally at the shoulder joint between the scapula and humerus, where the musculature is markedly developed. This proximal control pattern appears to be shared among cetaceans despite substantial differences in flipper size and external morphology. Beyond its anatomical implications this study provides photographic documentation of key flipper structures across cetacean groups and demonstrates that UV-light imaging is an effective tool for revealing internal soft-tissue anatomy. This approach is likely to be valuable for the study of other anatomical systems.</p>","PeriodicalId":14971,"journal":{"name":"Journal of Anatomy","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2026-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13398920/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148470682","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Transcriptomic profiling of subpopulations of mouse embryonic subplate neurons.","authors":"Hitomi Achiwa, Yuichiro Hara, Hideya Kawaji, Minori Oshima, Noe Kaneko, Ayumu Morioka, Anna Hoerder-Suabedissen, Zoltán Molnár, Chiaki Ohtaka-Maruyama","doi":"10.1111/joa.70197","DOIUrl":"10.1111/joa.70197","url":null,"abstract":"<p><p>Subplate neurons (SpNs) are among the earliest-born and maturing neurons in the developing cerebral cortex. They arise from multiple origins and can be classified into several subgroups based on morphology, connectivity, and gene expression. These neurons play essential roles in cortical circuit formation, yet their cellular diversity and transcriptional dynamics remain incompletely understood. Here, we characterized transcriptomic profiles of SpN subpopulations in embryonic mouse cortex using Lpar1-EGFP and NeuroD1/Cre-ERT2 (D1B) reporter lines. We applied complementary approaches of gene expression profiling, including bulk microarray analysis, single-cell RNA sequencing (scRNA-seq), and Visium spatial transcriptomics. At embryonic day 17 (E17), scRNA-seq identified 10 distinct Lpar1-EGFP-positive SpN clusters, which spatial transcriptomics mapped to specific cortical regions. While many markers showed enrichment within the subplate region, others extended into the hippocampus and ventral pallium (including the amygdala, claustrum, and endopiriform nucleus). Integrated analysis of Lpar1-EGFP and D1B lines revealed both overlapping and unique gene expression signatures, highlighting dynamic markers of subplate identity. Comparisons between E15 and E17 datasets showed substantial transcriptional shifts, suggesting rapid developmental changes in SpN subgroups. Validation with in situ hybridization and RNAscope confirmed the selectivity of key markers, including Cryab, Cdh13, Nr4a2, and Lmo3. Together, these findings provide a molecular framework for further classifying SpN subtypes and identifying candidate markers for transient versus persistent populations, thereby advancing our understanding of early cortical development.</p>","PeriodicalId":14971,"journal":{"name":"Journal of Anatomy","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2026-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13398646/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148470699","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}