Journal of Anaesthesiology, Clinical Pharmacology最新文献

Superior vena cava and right pulmonary artery junction - An intraoperative transesophageal echocardiographic landmark for central venous catheter tip position: A prospective observational study. 上腔静脉和右肺动脉交界处——术中经食管超声心动图标志中心静脉导管尖端位置：一项前瞻性观察研究。

IF 1.5

Journal of Anaesthesiology, Clinical Pharmacology Pub Date : 2025-07-01 Epub Date: 2025-06-19 DOI: 10.4103/joacp.joacp_103_24

A Jagadish, Saravana Babu, Subin Sukesan, Prasanta K Dash, Shrinivas V Gadhinglajkar, Bineesh K Radhakrishnan

{"title":"Superior vena cava and right pulmonary artery junction - An intraoperative transesophageal echocardiographic landmark for central venous catheter tip position: A prospective observational study.","authors":"A Jagadish, Saravana Babu, Subin Sukesan, Prasanta K Dash, Shrinivas V Gadhinglajkar, Bineesh K Radhakrishnan","doi":"10.4103/joacp.joacp_103_24","DOIUrl":"10.4103/joacp.joacp_103_24","url":null,"abstract":"Background and aims: The main aim of this study was to evaluate the efficacy of real-time intraoperative transesophageal echocardiography (TEE) in guiding the central venous catheter (CVC) tip placement at the superior vena cava (SVC)-right pulmonary artery (RPA) junction.Materials and methods: One hundred patients aged between 18 and 65 years undergoing elective cardiac surgery were enrolled in the study. In the operation room, under ultrasound guidance, right internal jugular vein was punctured and CVC was inserted. The primary outcome was to determine the accuracy of placing the CVC tip under TEE guidance at the SVC-RPA junction by intraoperative surgical palpation and to correlate between the preoperative chest radiograph-predicted CVC depth and the TEE-guided placement of CVC depth. The secondary outcomes were to evaluate the position of CVC tip in relation to the carina in postoperative chest radiograph and the incidence of complications.Results: A total of 98 patients were included in the analysis. The CVC tip was palpable by the surgeon intraoperatively at the SVC-RPA junction in 76 patients (77.6%). A significant direct correlation was observed between the predicted preoperative CVC depth and TEE-guided placement of CVC depth (r = 0.7441, P < 0.0001). In the postoperative chest radiograph, 78 (79.5%) patients had the CVC tip positioned above the carina. Twenty-nine patients had atrial ectopics and six patients had ventricular ectopics during CVC insertion.Conclusions: TEE-guided SVC-RPA junction is an accurate landmark for the intraoperative positioning of CVC tip in the extra-pericardial portion of SVC to prevent life-threatening cardiac complications.","PeriodicalId":14946,"journal":{"name":"Journal of Anaesthesiology, Clinical Pharmacology","volume":"41 3","pages":"427-432"},"PeriodicalIF":1.5,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12237190/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144600543","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ultrasound as a tool for rapid diagnosis of life-threatening acute compartment syndrome during percutaneous nephrolithotomy. 超声作为经皮肾镜取石术中危及生命的急性室室综合征的快速诊断工具。

IF 1.5

Journal of Anaesthesiology, Clinical Pharmacology Pub Date : 2025-07-01 Epub Date: 2025-04-10 DOI: 10.4103/joacp.joacp_270_24

Abhyuday Kumar, Vinnakota N Padmavathi, Swapnil Tiwari, Kamlesh Gunjan

引用次数: 0

Unveiling the superior analgesic: Thoracic epidural versus intrathecal morphine in open live donor hepatectomy - A randomized controlled trial. 揭示优越的镇痛：胸椎硬膜外吗啡与鞘内吗啡在开放式供肝切除术中的应用——一项随机对照试验。

IF 1.5

Journal of Anaesthesiology, Clinical Pharmacology Pub Date : 2025-07-01 Epub Date: 2025-02-10 DOI: 10.4103/joacp.joacp_173_24

Rohit Saini, Gaurav Sindwani, Neha Garg, Mahesh K Arora, Viniyendra Pamecha, Nihar Mohapatra

{"title":"Unveiling the superior analgesic: Thoracic epidural versus intrathecal morphine in open live donor hepatectomy - A randomized controlled trial.","authors":"Rohit Saini, Gaurav Sindwani, Neha Garg, Mahesh K Arora, Viniyendra Pamecha, Nihar Mohapatra","doi":"10.4103/joacp.joacp_173_24","DOIUrl":"10.4103/joacp.joacp_173_24","url":null,"abstract":"Background and aims: Postoperative pain management in open live donor hepatectomy is vital. This study aimed to compare postoperative analgesia provided by intrathecal morphine (ITM) and epidural in open live donor hepatectomy.Material and methods: Patients were divided into two groups. In the epidural (EPI) group, a bolus dose of 0.125% levobupivacaine (5-6 mL) with 3 mg of preservative-free morphine (diluted in 5 mL of 0.9% normal saline) was injected. In the postoperative period, infusion of levobupivacaine 0.125% at a rate of 5-8 mL/hour was continued for 3 days. In the intrathecal group (ITM), 0.3 mg morphine with 1.5 mL of 0.5% bupivacaine heavy was injected. General anesthesia was administered. Postoperatively, both groups received intravenous fentanyl patient-controlled analgesia. Numerical rating score (NRS) scores were recorded at 0, 2, 4, 12, 24, 36, 48, and 72 hours postoperatively. Data were analyzed using the Student t-test, Mann-Whitney U test, and Fisher's exact test. P < 0.05 was considered significant.Results: A total of 60 patients were enrolled. The postoperative fentanyl consumption for the first 24 hours was significantly higher in the EPI group compared to the ITM group (162.5 mcg vs. 75 mcg, respectively; P = 0.023). NRS up to 12 hours in the postoperative period at rest, on movement, and for shoulder pain were significantly lower in the ITM group compared to the EPI group (P = 0.000).Conclusions: ITM significantly decreased fentanyl consumption in the first 24 hours when compared to the epidural group in patients undergoing open donor hepatectomy.","PeriodicalId":14946,"journal":{"name":"Journal of Anaesthesiology, Clinical Pharmacology","volume":"41 3","pages":"441-447"},"PeriodicalIF":1.5,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12237148/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144600548","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A prospective study on the administration and titration of oxygen therapy in mechanically ventilated patients. 机械通气患者氧治疗给药及滴定的前瞻性研究。

IF 1.5

Journal of Anaesthesiology, Clinical Pharmacology Pub Date : 2025-07-01 Epub Date: 2025-02-22 DOI: 10.4103/joacp.joacp_199_24

Saurabh Chandrakar, Ankit Agarwal, Gaurav Jain, R Udhayachandhar, Davis Cherian, Nupur B Patel

{"title":"A prospective study on the administration and titration of oxygen therapy in mechanically ventilated patients.","authors":"Saurabh Chandrakar, Ankit Agarwal, Gaurav Jain, R Udhayachandhar, Davis Cherian, Nupur B Patel","doi":"10.4103/joacp.joacp_199_24","DOIUrl":"10.4103/joacp.joacp_199_24","url":null,"abstract":"Background and aims: Medical oxygen (O2) is a lifesaving therapy in the intensive care unit (ICU). However, overzealous use and poorly defined O2 targets in ICU patients can increase the risk of hyperoxemia. We aimed to assess the administration and titration of O2 therapy in ICU patients requiring invasive mechanical ventilation (IMV) support.Material and methods: In this prospective observational study, all adult patients requiring IMV for more than 24 hours were included over 1 year (December 2020-November 2021). Patients who refused to give consent or required IMV support for less than 24 hours, did not have arterial blood gas data, were at risk for imminent death, or required extracorporeal membrane oxygenation or hyperoxemia therapy were excluded. We calculated the incidence of hyperoxemia (SpO2 > 98%), physicians' response to hyperoxemia, and factors associated with hyperoxemia. Multivariable logistic regression (MLR) analysis was done to assess factors associated with hyperoxemia.Results: Among 400 recruited patients and 4631 observations, 211 patients and 1669 observations had hyperoxemia. In 398 observations, oxygen was decreased. Physicians were reluctant to decrease oxygen when hyperoxemia was observed at lower inspired oxygen (χ2 = 182.1, P value < 0.001). On MLR analysis, the duration of IMV, minute ventilation, and inspired and partial pressure of oxygen were statistically significantly associated with hyperoxemia.Conclusions: Hyperoxemia was observed in approximately one-third of observations noted in mechanically ventilated patients. Physicians were reluctant to decrease oxygen when hyperoxemia was encountered at lower inspired oxygen.","PeriodicalId":14946,"journal":{"name":"Journal of Anaesthesiology, Clinical Pharmacology","volume":"41 3","pages":"433-440"},"PeriodicalIF":1.5,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12237278/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144600509","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comment on an unidentifiably severed LMA supreme: An unanticipated critical incident. 评论一个无法识别的切断LMA最高：一个意外的关键事件。

IF 1.5

Journal of Anaesthesiology, Clinical Pharmacology Pub Date : 2025-07-01 Epub Date: 2025-04-10 DOI: 10.4103/joacp.joacp_438_24

Ravneet K Gill

引用次数: 0

Comparison of cuff inflation-deflation technique and conventional technique for nasotracheal intubation using C-Mac video laryngoscope: A prospective randomised controlled trial. C-Mac视频喉镜下袖带充气-放气技术与常规鼻气管插管技术的比较：一项前瞻性随机对照试验。

IF 1.5

Journal of Anaesthesiology, Clinical Pharmacology Pub Date : 2025-07-01 Epub Date: 2025-04-10 DOI: 10.4103/joacp.joacp_273_24

Venkata P K Sangamala, Rashmi Syal, Rakesh Kumar, Pradeep Bhatia, Sadik Mohammed, Manoj Kamal

{"title":"Comparison of cuff inflation-deflation technique and conventional technique for nasotracheal intubation using C-Mac video laryngoscope: A prospective randomised controlled trial.","authors":"Venkata P K Sangamala, Rashmi Syal, Rakesh Kumar, Pradeep Bhatia, Sadik Mohammed, Manoj Kamal","doi":"10.4103/joacp.joacp_273_24","DOIUrl":"10.4103/joacp.joacp_273_24","url":null,"abstract":"Background and aims: In traditional nasotracheal intubation (NTI), the tracheal tube is inserted through the nostril and manipulated in the pharynx to guide it into the trachea using additional maneuvers such as BURP (backward upward rightward pressure) maneuver, neck movement, tube rotation, the use of a bougie, or Magill's or Boedeker forceps under laryngoscopy guidance. These maneuvers often increase the time required for intubation, the risk of cuff rupture, and hemodynamic stress. The cuff inflation technique is an alternative NTI approach, where the cuff of the tube is inflated with air to help align with the tracheal opening.Material and methods: All surgical patients requiring NTI were randomly allocated into two groups (n = 53 each): Group C, using the conventional intubation technique, and Group I, using the cuff inflation-deflation technique. Intubation time, types of maneuvers, number of maneuvers, hemodynamic response, percentage of glottic opening (POGO) score, and complications were evaluated.Results: The cuff inflation technique required significantly less time for successful NTI compared to the conventional group (27.86 ± 4.47 s vs. 41.11 ± 10.98 s, respectively; P < 0.0001). Additionally, the number of accessory maneuvers required, hemodynamic stress responses, and complications were significantly reduced (P < 0.00277) with the cuff inflation technique compared to the conventional technique.Conclusions: The cuff inflation method requires significantly less time for NTI compared to the conventional method. Additionally, the cuff inflation method facilitates faster alignment with the glottis inlet, reduces hemodynamic responses, minimizes the need for maneuverability, and results in fewer complications.","PeriodicalId":14946,"journal":{"name":"Journal of Anaesthesiology, Clinical Pharmacology","volume":"41 3","pages":"510-515"},"PeriodicalIF":1.5,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12237172/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144600519","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

External oblique intercostal plane block in paediatric patients with thrombocytopenia for open splenectomy: Simple and promising…. 外斜肋间平面阻滞治疗血小板减少症患儿开腹脾切除术：简单而有前景....

IF 1.5

Journal of Anaesthesiology, Clinical Pharmacology Pub Date : 2025-07-01 Epub Date: 2025-03-22 DOI: 10.4103/joacp.joacp_229_24

Shruti Shrey, Chandni Sinha, Amarjeet Kumar, Ajeet Kumar, Vikram Chandra

引用次数: 0

Is there a need for a 2 mL ampule of 0.5% hyperbaric bupivacaine? 是否需要2ml 0.5%高压布比卡因？

IF 1.5

Journal of Anaesthesiology, Clinical Pharmacology Pub Date : 2025-07-01 Epub Date: 2025-04-10 DOI: 10.4103/joacp.joacp_367_24

Teena Bansal, Suresh Singhal

引用次数: 0

Laryngeal mask airway proseal versus laryngeal mask airway protector for laparoscopic surgery: A randomized comparative study. 腹腔镜手术中喉罩与喉罩气道保护器的随机比较研究。

IF 1.5

Journal of Anaesthesiology, Clinical Pharmacology Pub Date : 2025-07-01 Epub Date: 2025-03-22 DOI: 10.4103/joacp.joacp_430_24

Vinod K Srivastava, Rajesh Raman, Rati Prabha, Deshraj Verma, Brij B Kushwaha, Shefali Gautam

{"title":"Laryngeal mask airway proseal versus laryngeal mask airway protector for laparoscopic surgery: A randomized comparative study.","authors":"Vinod K Srivastava, Rajesh Raman, Rati Prabha, Deshraj Verma, Brij B Kushwaha, Shefali Gautam","doi":"10.4103/joacp.joacp_430_24","DOIUrl":"10.4103/joacp.joacp_430_24","url":null,"abstract":"Background and aims: Laryngeal Mask Airway Protector (LMPt) and Laryngeal Mask Airway Proseal (LMPs) have a high oropharyngeal leak pressure (OLP) but have not been compared for laparoscopic surgery. It was hypothesized that LMPs and LMPt have different clinical performances while managing the airway of patients undergoing laparoscopic surgery. The aim of the study was to compare the LMPs and LMPt for managing the airway of patients undergoing laparoscopic surgery.Material and methods: This was a prospective, single-blind, randomized, comparative trial. It included adult patients of either gender with American Society of Anesthesiologists physical status I/II planned for elective laparoscopic surgery. The airway of the recruited subjects was managed with either LMPs (group R, n = 60) or LMPt (group T, n = 60). OLP was the primary outcome variable. Number of attempts, insertion success, device insertion duration, ease of insertion, hemodynamics, gastric tube insertion, and complications were secondary outcome variables. Numerical data and dichotomous data were analyzed using student's t-test and χ2 test, respectively.Results: The OLP was statistically greater (P < 0.001) in group T before (30.23 ± 1.48 vs. 25.33 ± 1.40 cm H2O) and during (31.77 ± 0.65 vs. 27.12 ± 1.11 cm H2O) the pneumoperitoneum. The baseline and secondary outcome variables were statistically similar between the groups.Conclusions: For patients undergoing elective laparoscopic surgery, both LMPt and LMPs are suitable for airway management, but LMPt provides a higher OLP. More trials are required to validate these findings across different surgical settings and patient populations.","PeriodicalId":14946,"journal":{"name":"Journal of Anaesthesiology, Clinical Pharmacology","volume":"41 3","pages":"532-537"},"PeriodicalIF":1.5,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12237236/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144600534","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Perioperative challenges and management strategies for non-cardiac surgery in patients with rheumatic heart diseases: A narrative review. 风湿性心脏病患者非心脏手术的围手术期挑战和管理策略：叙述性回顾

IF 1.5

Journal of Anaesthesiology, Clinical Pharmacology Pub Date : 2025-07-01 Epub Date: 2025-06-19 DOI: 10.4103/joacp.joacp_124_24

Manila Singh, Abey Abraham, Swati Chhabra Soni, Saket Singh

{"title":"Perioperative challenges and management strategies for non-cardiac surgery in patients with rheumatic heart diseases: A narrative review.","authors":"Manila Singh, Abey Abraham, Swati Chhabra Soni, Saket Singh","doi":"10.4103/joacp.joacp_124_24","DOIUrl":"10.4103/joacp.joacp_124_24","url":null,"abstract":"Rheumatic heart diseases (RHDs) impose a substantial global burden, primarily affecting individuals under 25 years of age in low- and medium-income countries (LMICs) and poor and marginalized groups in high-income countries.[123] The underlying cause is a group A beta-hemolytic streptococcus, which triggers an immune-mediated attack on the heart and joints. Although acute rheumatic fever (ARF) is treatable, its occurrence and complications remain high in impoverished areas.[4] Variations in social structure contribute to differences in the incidence and progression of the disease, even in affluent regions.[5] Administering anesthesia to this patient population presents significant challenges, particularly when early management has been inadequate due to limited medical care and follow-up. Literature shows evidence for anesthetic management of different types of RHDs, mostly focusing on mitral and aortic valvulopathies.[67] This review synthesizes literature from databases such as MEDLINE and PubMed searches from the year 2000 to date, focusing on anesthesia management strategies and the challenges posed by ARF and RHD. Specific topics covered include the diagnosis and management of ARF, acute complications, perioperative care for patients with RHD, and unique considerations for different valvular pathologiesWith this review, we aim to discuss the available evidence, current World Health Organization (WHO) and societal guidelines in the context of perioperative medical and anesthetic management, hemodynamic challenges, and postoperative courses. An emphasis on basic point-of-care ultrasound (POCUS) training is made in this review as the current era of diagnostics and therapeutics is increasingly reliant on echocardiography.","PeriodicalId":14946,"journal":{"name":"Journal of Anaesthesiology, Clinical Pharmacology","volume":"41 3","pages":"384-395"},"PeriodicalIF":1.5,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12237166/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144600537","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0