ChemPlusChem最新文献_第6页

Low-Energy Electron-Induced Dissociation of the Radiosensitizing Agent Sanazole. 放射性增敏剂Sanazole的低能电子诱导解离。

IF 3 4区化学

ChemPlusChem Pub Date : 2025-04-21 DOI: 10.1002/cplu.202500120

Farhad Izadi, Masoomeh Mahmoodi-Darian, Thomas F M Luxford, Jaroslav Kočišek, Stephan Denifl, Milan Ončák

{"title":"Low-Energy Electron-Induced Dissociation of the Radiosensitizing Agent Sanazole.","authors":"Farhad Izadi, Masoomeh Mahmoodi-Darian, Thomas F M Luxford, Jaroslav Kočišek, Stephan Denifl, Milan Ončák","doi":"10.1002/cplu.202500120","DOIUrl":"https://doi.org/10.1002/cplu.202500120","url":null,"abstract":"Sanazole is a hypoxic radiosensitizer for which the activation mechanism in cells has been suggested to involve initial reduction. Herein, electron attachment to sanazole under isolated conditions and upon microhydrations is investigated. Employing mass spectrometry supported by quantum chemical calculations, the anion formation mechanism and subsequent fragmentation pathways are examined. In the case of electron attachment to the isolated molecule, predominantly dissociative electron attachment is observed. The most prominent fragment anion, (NTR-yl)- at m/z 113, is suggested to be formed in an exothermic pathway through a single-bond dissociation, whereas other intense fragments require structural reorganization. The limited abundance of the parent anion under isolated conditions is altered upon microhydration conditions since in the latter situation only the (microhydrated) parent anion is observed. This result suggests that hydration closes and/or slows down the dissociation process and indicates that for sanazole, the initial mechanism of action in a reductive cell environment may be similar to that of well-studied nitroimidazole radiosensitizers.","PeriodicalId":148,"journal":{"name":"ChemPlusChem","volume":" ","pages":"e2500120"},"PeriodicalIF":3.0,"publicationDate":"2025-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143963576","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Coupling Co, N Co-Doped Carbon Nanotubes and PtCo Nanoparticles for Boosting Oxygen Reduction Reaction. Co， N共掺杂碳纳米管与PtCo纳米颗粒耦合促进氧还原反应。

IF 3 4区化学

ChemPlusChem Pub Date : 2025-04-19 DOI: 10.1002/cplu.202500076

Wen Feng, Congyue Sun, Xiaojin Li, Xiliang Luo, Wenqi Liu

{"title":"Coupling Co, N Co-Doped Carbon Nanotubes and PtCo Nanoparticles for Boosting Oxygen Reduction Reaction.","authors":"Wen Feng, Congyue Sun, Xiaojin Li, Xiliang Luo, Wenqi Liu","doi":"10.1002/cplu.202500076","DOIUrl":"https://doi.org/10.1002/cplu.202500076","url":null,"abstract":"The exploitation of an efficient and stable oxygen reduction reaction (ORR) catalyst plays a crucial role in the slow kinetics of the cathode in proton exchange membrane fuel cells. In this study, a catalyst loaded with PtCo alloys on Co and N co-doped carbon nanotubes (PtCoNC) is synthesized for oxygen reduction reaction, which has high activity and stability. The carbon nanotube structure provides efficient transport channels for reactant exchange and product transport, as well as provides a wealth of triple-phase sites, that improves the utilization of Pt. Further, the PtCoNC catalyst exhibits robust metal-support interactions, which can be attributed to the anchoring of the Co-Nx sites to Pt. Theoretical calculations indicating an increase in binding energy and a reduction in layer spacing provide conclusive verification of the presence of augmented interactions between PtCo nanoparticles and the support. As a result, the low Pt-loaded (0.025 mg cm-2) PtCoNC catalyst demonstrates superior ORR activity to that of commercial Pt/C with an impressive half-wave potential of 0.893 V vs reversible hydrogen electrode (RHE) in 0.1 M HClO4 solution. At 0.9 V vs RHE, its mass activity and specific activity are 3 and 2.6 times that of commercial Pt/C, respectively. It also shows better stability in acidic environment.","PeriodicalId":148,"journal":{"name":"ChemPlusChem","volume":" ","pages":"e2500076"},"PeriodicalIF":3.0,"publicationDate":"2025-04-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143952187","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Synthesis and Lubricating Properties of Bio-Based Lubricants from Palm Oil. 棕榈油生物基润滑油的合成及其润滑性能研究。

IF 3 4区化学

ChemPlusChem Pub Date : 2025-04-17 DOI: 10.1002/cplu.202500013

Jun Ye, Jiarui Zhang, Chaosheng Li, He Xu, Ming Sun, Lishu Xu, Lin Yu

{"title":"Synthesis and Lubricating Properties of Bio-Based Lubricants from Palm Oil.","authors":"Jun Ye, Jiarui Zhang, Chaosheng Li, He Xu, Ming Sun, Lishu Xu, Lin Yu","doi":"10.1002/cplu.202500013","DOIUrl":"https://doi.org/10.1002/cplu.202500013","url":null,"abstract":"This study explores the synthesis of bio-lubricants derived from palm oil, highlighting its potential as a sustainable alternative to petroleum-based lubricants. Through epoxidation and subsequent ring-opening reactions using isoamyl alcohol, palmitic acid esters (PAE), with enhanced thermal and oxidative stability is developed. Optimal ring-opening reaction conditions, identified as 100 °C with p-toluenesulfonic acid as the catalyst. The synthesized bio-lubricant PAE, exhibits superior tribological performance, achieving lower friction coefficients and reduced wear scar diameters compared to the original palm oil. Comparing PAE with palm oil, the average coefficient of friction is reduced by 9.8%, the PB value increased from 82 to 88 kg, and the PD value increased from 620 to 800 kg. The average grinding spot diameter decreased from about 600 to 500 μm, a decrease of 16.7%. These findings highlight its potential as a sustainable and effective industrial lubricant. This study underscores the significance of chemical modification in enhancing the performance of bio-lubricants and contributes to the development of environmentally friendly alternatives to traditional petroleum-based products, offering sustainable solutions for industrial lubrication needs.","PeriodicalId":148,"journal":{"name":"ChemPlusChem","volume":" ","pages":"e2500013"},"PeriodicalIF":3.0,"publicationDate":"2025-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143958746","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

High-Molecular-Weight Biodegradable CO₂/Propylene Oxide/Epichlorohydrin Terpolymers with Outstanding Gas Barrier Performance Synthesized Using an Organoboron Catalyst. 用有机硼催化剂合成具有优异气体阻隔性能的高分子量可生物降解CO2/环氧丙烷/环氧氯丙烷三元共聚物。

IF 3 4区化学

ChemPlusChem Pub Date : 2025-04-17 DOI: 10.1002/cplu.202500175

Yufei Liang, Tingting Zhao, Shuanjin Wang, Dongmei Han, Sheng Huang, Wei Liu, Hui Guo, Min Xiao, Yuezhong Meng

{"title":"High-Molecular-Weight Biodegradable CO2/Propylene Oxide/Epichlorohydrin Terpolymers with Outstanding Gas Barrier Performance Synthesized Using an Organoboron Catalyst.","authors":"Yufei Liang, Tingting Zhao, Shuanjin Wang, Dongmei Han, Sheng Huang, Wei Liu, Hui Guo, Min Xiao, Yuezhong Meng","doi":"10.1002/cplu.202500175","DOIUrl":"10.1002/cplu.202500175","url":null,"abstract":"As the sole commercial polycarbonate derived from CO2, poly(propylene carbonate) (PPC) is still hindered by poor thermal stability and a low glass transition temperature. Herein, first, the terpolymerization of CO2, propylene oxide (PO), and epichlorohydrin (ECH) to synthesize PPC-ECH terpolymers via one-pot and metal-free method using multinuclear organoboron catalysts is reported. The PPC-ECH terpolymers with well-rounded properties can be easily synthesized by adjusting reaction conditions, monomer ratios, catalyst types, and loading. The molecular weight of the PPC-ECH terpolymer can reach up to 59.4 kg mol-1, which is the highest known. Notably, the synthesized PPC-ECH exhibits outstanding barrier performance with oxygen permeability as low as 1.31 cm3 mm (m2 day)-1 and water vapor permeability as low as 0.016 g mm (m2 day)-1, significantly lower than those of pure PPC or other common packaging materials. Importantly, the introduction of a small amount of ECH not only preserves the biodegradability of polycarbonate but also markedly enhances its mechanical properties, glass transition temperature, thermal stability, and flame retardancy, offering promising prospects for application in packaging materials.","PeriodicalId":148,"journal":{"name":"ChemPlusChem","volume":" ","pages":"e2500175"},"PeriodicalIF":3.0,"publicationDate":"2025-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143953963","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Front Cover: Redox-Responsive Side Chain Structural Changes in a Seven-Membered Cyclic α,α-Disubstituted α-Amino Acid with a Disulfide Bond Enable Reversible Conformational Changes in Peptides (ChemPlusChem 4/2025) 封面：具有二硫键的七元环α，α-二取代α-氨基酸的氧化还原响应侧链结构变化使多肽的可逆构象改变（ChemPlusChem 4/2025）

IF 3 4区化学

ChemPlusChem Pub Date : 2025-04-15 DOI: 10.1002/cplu.202580401

Dr. Makoto Oba, Hikaru Nonaka, Dr. Tomohiro Umeno, Dr. Takuma Kato, Dr. Mitsunobu Doi, Dr. Atsushi Ueda, Dr. Masakazu Tanaka

引用次数: 0

A Machine Learning Approach for Prediction of Faradaic Efficiency in Electrochemical CO₂ Reduction on Nitrogen-Doped Carbon. 用机器学习方法预测氮掺杂碳上电化学还原CO2的法拉第效率。

IF 3 4区化学

ChemPlusChem Pub Date : 2025-04-15 DOI: 10.1002/cplu.202400766

Ganesan Raman

{"title":"A Machine Learning Approach for Prediction of Faradaic Efficiency in Electrochemical CO2 Reduction on Nitrogen-Doped Carbon.","authors":"Ganesan Raman","doi":"10.1002/cplu.202400766","DOIUrl":"https://doi.org/10.1002/cplu.202400766","url":null,"abstract":"Nitrogen-doped carbon materials are promising catalysts for electrochemical CO2 reduction, yet achieving high Faradaic efficiency for CO production remains challenging due to the competing hydrogen evolution reaction . To accelerate catalyst design, a machine learning-based stacked model is developed, integrating random forest and XGBoost (XGB) as base models with linear regression as a meta-model. This approach mitigates overfitting, achieving superior predictive performance (R2 = 0.98 train, 0.91 test) compared to XGB alone (R2 = 0.99 train, 0.86 test). SHapley Additive exPlanations (SHAP) analysis identifies pyridinic nitrogen (N) as a key driver of CO selectivity but reveals that its influence varies with different carbon substrates. SHAP interaction analysis uncovers a strong synergy between pyridinic-N and graphitic-N, where their combined impact on CO production exceeds their individual effects. Furthermore, the optimal pyridinic-N content depends on the carbon structure with distinct SHAP clustering for materials like graphene and carbon black. These insights provide a data-driven strategy for optimizing N-doped carbon catalysts, enabling targeted material selection to enhance CO2 reduction to CO.","PeriodicalId":148,"journal":{"name":"ChemPlusChem","volume":" ","pages":"e2400766"},"PeriodicalIF":3.0,"publicationDate":"2025-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143959225","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

N-Aryl or N-Alkyl Pyridinium-Substituted Excited-State Intramolecular Proton Transfer Fluorophores. n -芳基或n -烷基吡啶取代激发态分子内质子转移荧光团。

IF 3 4区化学

ChemPlusChem Pub Date : 2025-04-15 DOI: 10.1002/cplu.202500138

Timothée Stoerkler, Gilles Ulrich, Adèle D Laurent, Denis Jacquemin, Julien Massue

引用次数: 0

Methylthiolation Modified Bay-Annulated Indigo Derivatives for Enhanced Performance in Organic Field-Effect Transistors. 甲基巯基化修饰的海湾环靛蓝衍生物在有机场效应晶体管中的应用。

IF 3 4区化学

ChemPlusChem Pub Date : 2025-04-14 DOI: 10.1002/cplu.202500168

Jingjing Zhao, Cui Wang, Nuoya Li, Liyan Chen, Di Wu, Jianlong Xia

{"title":"Methylthiolation Modified Bay-Annulated Indigo Derivatives for Enhanced Performance in Organic Field-Effect Transistors.","authors":"Jingjing Zhao, Cui Wang, Nuoya Li, Liyan Chen, Di Wu, Jianlong Xia","doi":"10.1002/cplu.202500168","DOIUrl":"https://doi.org/10.1002/cplu.202500168","url":null,"abstract":"Indigo is one of the most well-known natural dyes and has attracted significant research interest due to its low cost and exceptional stability. Notably, bay-annulated indigo (BAI) has been reported as an effective electron acceptor and is widely used in various applications. Herein, a methylthio-substituted BAI derivative, compound 1, is successfully synthesized and the impact of methylthio substitution on its optoelectronic properties is investigated. UV-vis absorption and fluorescence spectra reveal that compound 1 displays a significant redshift compared to the nonmethylthio-substituted compound 2. Cyclic voltammetry measurements and density functional theory calculations indicate that compound 1 has a narrower highest occupied molecular orbital and lowest unoccupied molecular orbital gap, demonstrating the prominent influence of methylthio side chains in modulating molecular electronic properties. Importantly, the organic field-effect transistor device based on compound 1 exhibits a hole mobility 3.5 times higher than that of the nonmethylthio-substituted compound 2. Furthermore, atomic force microscopy characterization reveals the formation of needle-like crystallites in the compound 1 film after annealing, whereas compound 2 forms an amorphous thin film. These results suggest that methylthiolation is an effective strategy for tuning intermolecular interactions in novel BAI derivatives, and compound 1 is a promising hole-transporting material.","PeriodicalId":148,"journal":{"name":"ChemPlusChem","volume":" ","pages":"e2500168"},"PeriodicalIF":3.0,"publicationDate":"2025-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143954124","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Carbonyl and Carbonyl-N-Heterocyclic Carbine-Ligated Iron Complexes as Catalysts for Markovnikov-Selective Alkyne Hydrothiolation and Hydroselenation Reactions: A Mechanistic Study. 羰基和羰基- n -杂环碳-铁配合物作为马尔可夫尼科夫选择性炔氢硫化和氢硒化反应催化剂的机理研究。

IF 3 4区化学

ChemPlusChem Pub Date : 2025-04-14 DOI: 10.1002/cplu.202400731

Sobhana Reshma, Elambalassery G Jayasree

引用次数: 0

Sustainable Synthesis, Characterization, Cellular Effects of Gold Nanoparticles and Their Applications as Therapeutics in Cancer Therapy. 金纳米颗粒的可持续合成、表征、细胞效应及其在癌症治疗中的应用。

IF 3 4区化学

ChemPlusChem Pub Date : 2025-04-11 DOI: 10.1002/cplu.202400783

Youfeng Yue, Akihiro Moriyama, Marie Mita, Yue Yu

{"title":"Sustainable Synthesis, Characterization, Cellular Effects of Gold Nanoparticles and Their Applications as Therapeutics in Cancer Therapy.","authors":"Youfeng Yue, Akihiro Moriyama, Marie Mita, Yue Yu","doi":"10.1002/cplu.202400783","DOIUrl":"https://doi.org/10.1002/cplu.202400783","url":null,"abstract":"In recent years, gold nanoparticles (AuNPs) have attracted much attention due to their extensive applications in fields such as biomedicine, electronics, catalysis, and environmental science. However, traditional chemical methods for AuNPs synthesis present certain challenges, such as the use of harsh chemicals and high energy consumption. These limitations have led to the development of alternative, sustainable synthesis methods that are efficient, cost-effective, and environmentally friendly. These methods focus on the principle of green chemistry, utilizing renewable biomass sources (e.g., plant tissues, bacteria, fungi, and algae) and nontoxic solvents to minimize environmental impact. Biomolecules derived from biomass, such as polyphenols, proteins, and unsaturated fatty acids, enable the synthesis of AuNPs under mild and eco-friendly conditions. This review provides a comprehensive overview of recent advancements in the sustainable synthesis and applications of AuNPs. It summarizes the specific active compounds that drive the reduction and stabilization of AuNPs. It also explores the characterization techniques and underlying mechanisms involved in synthesis. Furthermore, their cellular effects and long-term safety are discussed, along with their extensive applications in biomedical fields, including bioimaging and cancer therapies. Finally, the potential of AuNPs is summarized, highlighting future perspectives as well as emerging opportunities and challenges in biological applications.","PeriodicalId":148,"journal":{"name":"ChemPlusChem","volume":" ","pages":"e2400783"},"PeriodicalIF":3.0,"publicationDate":"2025-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143952075","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0