ChemPlusChem最新文献

Cobalt Phthalocyanine Doping-Induced Electronic Modulation in Metal-Organic Framework-Derived Co₃O₄ and Boosted Alkaline Oxygen Evolution Reaction to Ampere Level. 酞菁钴掺杂诱导金属-有机骨架衍生Co3O4的电子调制及促进碱氧析出反应至安培水平。

IF 2.8 4区化学

ChemPlusChem Pub Date : 2026-05-01 DOI: 10.1002/cplu.70168

Clara Ghali, Joshuah Tavarez, Paulina Pietrzyk-Thel, Marianna Gniadek, Magdalena Osial, Agata Roszkiewicz, Boka Fikadu, Sohrab Asgaran, Jaebeom Lee, Michael Giersig, Justyna Widera-Kalinowska, Nwaji Njemuwa

{"title":"Cobalt Phthalocyanine Doping-Induced Electronic Modulation in Metal-Organic Framework-Derived Co3O4 and Boosted Alkaline Oxygen Evolution Reaction to Ampere Level.","authors":"Clara Ghali, Joshuah Tavarez, Paulina Pietrzyk-Thel, Marianna Gniadek, Magdalena Osial, Agata Roszkiewicz, Boka Fikadu, Sohrab Asgaran, Jaebeom Lee, Michael Giersig, Justyna Widera-Kalinowska, Nwaji Njemuwa","doi":"10.1002/cplu.70168","DOIUrl":"https://doi.org/10.1002/cplu.70168","url":null,"abstract":"The oxygen evolution reaction (OER) using noble metal-based catalysts faced significant commercialization challenges due to the scarcity and substantial expense of these noble metals. Thus, the development of an efficient OER electrocatalyst for proton exchange membrane (PEM) water electrolyzers is still a challenging task. Herein, we present a facile approach to preparing cobalt phthalocyanine anchored on N-doped Co3O4 carbon network (Co3O4-NC) derived from metal organic framework (MOF). This strategy facilitates fast electron transfer and modulates the electronic structure. This improved electron transport induced by CoPc plays a significant role in enhancing OER, requiring only an overpotential of 1.2 V to deliver a current density of 1000 mA cm-2 with excellent stability. The Co3O4-NC2 Pc catalyst shows excellent durability during PEM water electrolysis and delivers industrially required current density of 1000 mA cm-2 at a potential of 1.66 V, outperforming commercial RuO2. The results of this research are twofold. Firstly, they promote green and low-carbon development. Secondly, they inject new vitality into the development of hydrogen energy technologies.","PeriodicalId":148,"journal":{"name":"ChemPlusChem","volume":"91 5","pages":"e70168"},"PeriodicalIF":2.8,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147855519","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

V-, Nb- and Ta-Based Additives for Enhancing the Hydrogen Storage Performance of MgH₂: A Review. V-、Nb-和ta基添加剂提高MgH2储氢性能的研究进展

IF 2.8 4区化学

ChemPlusChem Pub Date : 2026-05-01 DOI: 10.1002/cplu.70172

Baochao Li, Shuyan Guan, Muhammad Moeen, Guangxin Fan, Baozhong Liu

{"title":"V-, Nb- and Ta-Based Additives for Enhancing the Hydrogen Storage Performance of MgH2: A Review.","authors":"Baochao Li, Shuyan Guan, Muhammad Moeen, Guangxin Fan, Baozhong Liu","doi":"10.1002/cplu.70172","DOIUrl":"https://doi.org/10.1002/cplu.70172","url":null,"abstract":"As a highly anticipated potential hydrogen storage material, magnesium hydride (MgH2) has shown important application prospects due to its high hydrogen storage capacity and abundant resource reserves. However, it still faces limitations in hydrogen storage performance in practical applications, including high dehydrogenation temperature, slow hydrogen absorption and desorption kinetics, and insufficient cycle stability, which restrict its large-scale application. In recent years, research has shown that introducing transition-metal-based additives is one of the effective strategies to enhance the hydrogen storage performance of MgH2. Transition-metal-based additives can significantly optimize the hydrogen absorption/desorption kinetic behavior of MgH2, manifested by effectively reducing reaction temperature, increasing reaction rate, and enhancing the cycling stability of the system. Among numerous transition metals, the fifth-group-element (vanadium, niobium, tantalum)-based additives have shown significant effects on improving the hydrogen storage performance of MgH2 due to their unique electronic structure and catalytic activity. This article systematically reviews the effects and mechanisms of vanadium-, niobium-, and tantalum-based additives on the hydrogen storage performance of MgH2, summarizes current research progress, and looks forward to future development directions in this field.","PeriodicalId":148,"journal":{"name":"ChemPlusChem","volume":"91 5","pages":"e70172"},"PeriodicalIF":2.8,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147855578","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Temperature-Buffer Interplay Governs the Formation, Stability, and Degradation of POEGMA Nanogels. 温度-缓冲液的相互作用决定了POEGMA纳米凝胶的形成、稳定性和降解。

IF 2.8 4区化学

ChemPlusChem Pub Date : 2026-05-01 DOI: 10.1002/cplu.202500725

Katarzyna Filipek, Łukasz Otulakowski, Daria Lipowska-Kur, Anna Celny, Agnieszka Kowalczuk, Alicja Utrata-Wesołek

{"title":"Temperature-Buffer Interplay Governs the Formation, Stability, and Degradation of POEGMA Nanogels.","authors":"Katarzyna Filipek, Łukasz Otulakowski, Daria Lipowska-Kur, Anna Celny, Agnieszka Kowalczuk, Alicja Utrata-Wesołek","doi":"10.1002/cplu.202500725","DOIUrl":"https://doi.org/10.1002/cplu.202500725","url":null,"abstract":"Recent advancements in soft nanomaterials have positioned nanogels at the interface of polymer chemistry and biomedicine, as they combine the physicochemical features of nanoparticles with the three-dimensional, water-swollen architecture of hydrogels. This study explored the formation and properties of degradable nanogels from thermoresponsive poly[oligo(ethylene glycol) methacrylates] (POEGMA), indicating their potential as drug carriers. The research underscored the importance of biologically relevant conditions, as nanogel formation and degradation were more challenging in buffer solutions (citrate and PBS) than in water. During synthesis through dual thermal and chemical crosslinking, aggregation occurred when the milieu temperature exceeded the polymers' cloud point temperature (TCP), revealing a medium and temperature-dependent processing regime. Obtaining nanogels of suitable size required an appropriate temperature gap between the polymer's TCP and the temperature of the biological medium. Nanogel degradation in citrate buffer and PBS was followed by dynamic light scattering and cryogenic transmission electron microscopy, and encapsulation and release of doxorubicin hydrochloride were demonstrated. Our findings highlight that translation from simplified aqueous solutions to biological media fundamentally alters nanogel formation, stability and degradation pathways. By identifying temperature-medium interdependencies as a key design parameter, this work provides chemically grounded guidelines for the rational development of nanogels made of thermoresponsive polymers intended for future applications.","PeriodicalId":148,"journal":{"name":"ChemPlusChem","volume":"91 5","pages":"e202500725"},"PeriodicalIF":2.8,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147855521","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Enhanced Durability and Recyclability of Copper(II) Catalysts in Chan-Evans-Lam Coupling Reactions. 铜（II）催化剂在Chan-Evans-Lam偶联反应中的增强耐久性和可回收性。

IF 2.8 4区化学

ChemPlusChem Pub Date : 2026-05-01 DOI: 10.1002/cplu.202500731

Ketan Maru, Sarita Kalla, Ritambhara Jangir

{"title":"Enhanced Durability and Recyclability of Copper(II) Catalysts in Chan-Evans-Lam Coupling Reactions.","authors":"Ketan Maru, Sarita Kalla, Ritambhara Jangir","doi":"10.1002/cplu.202500731","DOIUrl":"https://doi.org/10.1002/cplu.202500731","url":null,"abstract":"Copper-catalyzed Chan-Evans-Lam (CEL) coupling has emerged as a powerful method for CN bond formation under mild conditions. In this study, a novel monodentate ligand, 4-((2,3,5,6-tetramethylbenzyl)amino)benzoic acid (TMABH), was rationally designed to construct copper paddlewheel-based architectures for CEL catalysis. The NH linkage in TMABH was deliberately incorporated as it acts as Lewis basic sites, facilitating proton transfer and stabilizing catalytic intermediates during CN coupling. Two distinct copper materials were synthesized: (i) a discrete dinuclear paddlewheel complex, [(Cu2(TMAB)4(DMF)2)]·4DMF (referred here as CuII-0D), and (ii) a coordination polymer, {[(Cu2(TMAB)4(4,4'-bipyridine)2)]}n (CuII-1D), enabling a direct comparison of structural effects on catalytic performance. Both catalysts were comprehensively characterized using single-crystal X-ray diffraction, powder X-ray diffraction, Fourier-transform infrared spectroscopy, thermogravimetric analysis, X-ray photoelectron spectroscopy, scanning electron microscopy, and CHN analyses. Catalytic evaluations revealed excellent activity across a range of arylboronic acids and Aniline in the presence of atmospheric oxygen, without requiring external oxidants. CuII-1D material serves as a robust heterogeneous catalyst with excellent recyclability, whereas its CuII-0D counterparts lose structural integrity after the first cycle, thereby limiting their reusability. This is the first report comparing the catalytic performance of discrete and polymeric copper paddlewheel frameworks derived from the same ligand, providing a clear structure-activity relationship. Furthermore, the study highlights the potential of copper paddlewheel-based architectures as robust, recyclable, and scalable heterogeneous catalysts for sustainable CN bond formation.","PeriodicalId":148,"journal":{"name":"ChemPlusChem","volume":"91 5","pages":"e202500731"},"PeriodicalIF":2.8,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147809048","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Selective Oxidation of Glycolaldehyde to Glyoxal Using Ruthenium Complex Catalysts. 钌络合催化剂选择性氧化乙醇醛制乙二醛。

IF 2.8 4区化学

ChemPlusChem Pub Date : 2026-05-01 DOI: 10.1002/cplu.202500616

Takuya Sagawa, Atsushi Kondo, Mineo Hashizume

{"title":"Selective Oxidation of Glycolaldehyde to Glyoxal Using Ruthenium Complex Catalysts.","authors":"Takuya Sagawa, Atsushi Kondo, Mineo Hashizume","doi":"10.1002/cplu.202500616","DOIUrl":"10.1002/cplu.202500616","url":null,"abstract":"Cellulose comprises glucose units, and therefore glucose and its derivatives have received attention as a carbon source replacing fossil fuels. In particular, glyoxal, which is obtained from glucose by retro-aldol reaction and subsequent oxidation via glycolaldehyde, is a feedstock for useful chemicals. However, efficient catalytic synthesis of glyoxal from glycolaldehyde has not been reported because the unwanted excessive oxidation of glyoxal occurs. In this study, catalytic synthesis of glyoxal from glycolaldehyde using a ruthenium complex catalyst with a bromophenyl terpyridine ligand was carried out. After optimizing reaction conditions, glyoxal was obtained in a 32% yield in N,N-dimethylformamide at 100°C for 3 h using O2 gas as an oxidant. Furthermore, the obtained mixture was reacted with sodium sulfite to form precipitates, which are bisulfite adducts. It could be easily separated as a glyoxal equivalent from the catalyst and solvent by filtration. These results indicate that a new method for the synthesis of glyoxal from biomass-derived glycolaldehyde has been achieved.","PeriodicalId":148,"journal":{"name":"ChemPlusChem","volume":"91 5","pages":"e202500616"},"PeriodicalIF":2.8,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13130154/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147758158","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Small-Molecule Photocatalytic Activation Through Noncovalent Interactions. 通过非共价相互作用的小分子光催化活化。

IF 2.8 4区化学

ChemPlusChem Pub Date : 2026-05-01 DOI: 10.1002/cplu.202500601

Sathi Sahoo, Tarun Kumar Dinda, Prasenjit Mal

{"title":"Small-Molecule Photocatalytic Activation Through Noncovalent Interactions.","authors":"Sathi Sahoo, Tarun Kumar Dinda, Prasenjit Mal","doi":"10.1002/cplu.202500601","DOIUrl":"https://doi.org/10.1002/cplu.202500601","url":null,"abstract":"Supramolecular chemistry explores how noncovalent interactions enable the association of multiple molecular components into structurally defined and functionally active assemblies, with molecular recognition arising from geometric, electronic, and chemical complementarity. Integrating these principles with photocatalysis is reshaping organic synthesis by introducing adaptive control over reactivity under visible light. Through Hbonding (hydrogen bonding), π-π stacking, host-guest encapsulation, charge-transfer complexation, hydrophobic effects, and σ-hole interactions (cation-π, anion-π, and halogen bonding), supramolecular photocatalysts dynamically organize substrates and modulate excited-state properties, thereby influencing reaction pathways and selectivity. Such assemblies can respond to changes in substrate identity, aggregation state, or irradiation conditions, enabling tunable and metal-free photochemical transformations. Inspired by biological photosystems, spatial confinement and electronic communication within supramolecular architectures further unlock unconventional reactivity beyond classical photocatalysis. This review article summarizes recent mechanistic insights and design strategies, positioning supramolecular photocatalysis as a versatile and sustainable platform for next-generation catalytic synthesis.","PeriodicalId":148,"journal":{"name":"ChemPlusChem","volume":"91 5","pages":"e202500601"},"PeriodicalIF":2.8,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147809083","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ru-Arene Complexes Bearing Chelated Pyrrole-2-Aldiminate: Synthesis, Structure, and Catalytic Application for Transfer Hydrogenation of Carbonyl Compounds. 含螯合吡咯-2- aldiminate的ru -芳烃配合物：合成、结构及其在羰基化合物转移加氢中的催化应用。

IF 2.8 4区化学

ChemPlusChem Pub Date : 2026-05-01 DOI: 10.1002/cplu.70176

Binoy Ghosh, Debopam Singha, Anushri Chandra, Samaresh Bhattacharya

{"title":"Ru-Arene Complexes Bearing Chelated Pyrrole-2-Aldiminate: Synthesis, Structure, and Catalytic Application for Transfer Hydrogenation of Carbonyl Compounds.","authors":"Binoy Ghosh, Debopam Singha, Anushri Chandra, Samaresh Bhattacharya","doi":"10.1002/cplu.70176","DOIUrl":"https://doi.org/10.1002/cplu.70176","url":null,"abstract":"Reactions of [{Ru(p-cymene)Cl2}2] with the four chosen pyrrole-2-aldimine (HL-R; R = OCH3, CH3, H, and Cl) ligand precursors in ethanol, using triethylamine as base, furnished complexes of the expected type, [Ru(p-cymene)(L-R)Cl], in good yields. The individual complexes are depicted as complex 1 (R = OCH3), 2 (R = CH3), 3 (R = H), and 4 (R = Cl). Molecular structures of complexes 2, 3, and 4 were determined by X-ray diffraction method, while the structure of complex 1 was optimized with DFT method. In their electronic spectra, all the complexes exhibited intense absorptions in the visible and ultraviolet regions, which were analyzed by TDDFT calculations. Electrochemical redox properties of the complexes were studied by cyclic voltammetry. Presence of the Ru-Cl moiety in these complexes indicated their potential to function as a catalyst-precursor in transfer-hydrogenation of organic substrates, which was explored toward transfer-hydrogenation of carbonyl compounds to the corresponding alcohols. Using 2-propanol as the provider of hydrogen and complex 1 as catalyst, hydrogenation of a variety of aldehydes and ketones could be achieved under relatively mild conditions, furnishing primary and secondary alcohols in very good isolated yields. A plausible mechanism for the observed catalysis has been proposed.","PeriodicalId":148,"journal":{"name":"ChemPlusChem","volume":"91 5","pages":"e70176"},"PeriodicalIF":2.8,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147855592","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Design, Synthesis, and Biological Activity Evaluation of Herbicidal Ionic Liquids Based on Quinclorac Anion for Potential Rice Protection. 基于氯代丙酸阴离子除草剂离子液体的设计、合成及生物活性评价

IF 2.8 4区化学

ChemPlusChem Pub Date : 2026-05-01 DOI: 10.1002/cplu.202500674

Yang Zhai, Mohamad Chadia Celestinah, Jili Ge, Ruizhong Lu, Zimo He, Tao Jiang, Yun Xu

{"title":"Design, Synthesis, and Biological Activity Evaluation of Herbicidal Ionic Liquids Based on Quinclorac Anion for Potential Rice Protection.","authors":"Yang Zhai, Mohamad Chadia Celestinah, Jili Ge, Ruizhong Lu, Zimo He, Tao Jiang, Yun Xu","doi":"10.1002/cplu.202500674","DOIUrl":"https://doi.org/10.1002/cplu.202500674","url":null,"abstract":"Quinclorac is a widely used selective herbicide that targets plant growth hormones. However, it exhibits poor water solubility, limited plant permeability, and dependence on adjuvants. To address these limitations, we synthesized a series of novel herbicidal ionic liquids (HILs) by pairing the quinclorac anion with various cations, including quaternary ammonium, imidazolium, morpholinium, and 4-hydroxypiperidinium. Compared with quinclorac, the resulting HILs exhibited markedly improved physicochemical properties, including enhanced solubility, reduced surface tension, and increased lipophilicity. Thermal analysis confirmed excellent stability, with decomposition temperatures above 200°C and vaporization enthalpies exceeding 120 kJ/mol. Surface activity measurements indicated lower critical micelle concentrations (CMC) and reduced contact angles (CA), promoting superior wetting and adhesion on plant surfaces. Greenhouse bioassays demonstrated enhanced herbicidal activity against barnyard grass, achieving inhibition rates above 80% at 225 g AI/ha without phytotoxic effects on rice. Notably, at low concentrations (225-375 g AI/ha), all HILs promoted rice growth, while at higher concentrations (525-675 g AI/ha), HIL3 and HIL4 (containing long-chain quaternary ammonium cations) and HIL5 (containing an imidazolium cation) exhibited significant growth-promoting effects. This study reports the first quinclorac-based HILs and highlights their potential as sustainable, efficient, and environmentally friendly alternatives to conventional herbicide formulations for rice cultivation.","PeriodicalId":148,"journal":{"name":"ChemPlusChem","volume":"91 5","pages":"e202500674"},"PeriodicalIF":2.8,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147809016","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Carbamate and Sulfamate Bioisosteres of N,N-Dimethyl-3β-Hydroxycholenamide as Ligands of the Liver X Receptors. N，N-二甲基-3β-羟基胆酰胺氨基甲酸酯和氨基甲酸酯生物同分酯作为肝脏X受体的配体。

IF 2.8 4区化学

ChemPlusChem Pub Date : 2026-05-01 DOI: 10.1002/cplu.202600007

Malena Pegenaute, Micaela B Pugliese, Facundo Perez, Florencia Di Salvo, Rosana I Misico, María V Dansey, Lautaro D Alvarez, Gerardo Burton, Mario D Martínez

{"title":"Carbamate and Sulfamate Bioisosteres of N,N-Dimethyl-3β-Hydroxycholenamide as Ligands of the Liver X Receptors.","authors":"Malena Pegenaute, Micaela B Pugliese, Facundo Perez, Florencia Di Salvo, Rosana I Misico, María V Dansey, Lautaro D Alvarez, Gerardo Burton, Mario D Martínez","doi":"10.1002/cplu.202600007","DOIUrl":"https://doi.org/10.1002/cplu.202600007","url":null,"abstract":"Modulating activity of liver X receptors (LXR) has garnered increasing interest, as its principal endogenous ligands, oxysterols, are implicated in diverse disorders, including atherosclerosis and metabolic syndrome. N,N-dimethyl-3β-hydroxycholenamide (DMHCA, 1), a synthetic LXR ligand, exhibits promising features and a favorable safety profile without elevating triglycerides or inducing hepatic steatosis. Here, we describe the synthesis, biological profile, and mode of action against LXR isoforms, of two novel side chain bioisosteric analogues of DMHCA (1) where the dimethylamide was replaced by a N,N-dimethyl carbamate (2) or sulfamate (3). These compounds were obtained in good yields via a simple synthetic sequence starting from stigmasterol, a readily available phytosterol byproduct from the soybean industry. Both analogues 2 and 3 exhibited agonistic activity comparable to DMHCA (1) in luciferase reporter assays in human HEK-293 T cells, although sulfamate (3) proved to be more effective (LXRα/1 pEC50 = 6.4; LXRβ/1 pEC50 = 6.4; LXRα/2 pEC50 = 5.3; LXRβ/2 pEC50 = 5.6; LXRα/3 pEC50 = 6.0; LXRβ/3 pEC50 = 6.1). Molecular dynamics simulations of the LXRβ/ligand complexes confirmed a stable binding mode consistent with the dose-response data in all cases. The results set the foundation for developing novel analogues based on these compounds, particularly with sulfamate (3).","PeriodicalId":148,"journal":{"name":"ChemPlusChem","volume":"91 5","pages":"e202600007"},"PeriodicalIF":2.8,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147758226","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Synthesis and Electrochemical Characterization of Nickel Germanate as an Electrode Material for Lithium-Ion Batteries. 锂离子电池电极材料锗酸镍的合成及电化学表征

IF 2.8 4区化学

ChemPlusChem Pub Date : 2026-05-01 DOI: 10.1002/cplu.70163

Darina A Krasilina, Anna A Grushina, Ekaterina K Khrapova, Ekaterina D Zharova, Aleksandr M Rumyantsev, Andrei A Krasilin

引用次数: 0