Jornal de pediatria最新文献_第8页

Transgenerational transmission of eating habits 饮食习惯的代代相传

IF 3.3 4区医学

Jornal de pediatria Pub Date : 2024-03-01 DOI: 10.1016/j.jped.2023.11.007

Mauro Fisberg, Nathalia Gioia, Priscila Maximino

{"title":"Transgenerational transmission of eating habits","authors":"Mauro Fisberg, Nathalia Gioia, Priscila Maximino","doi":"10.1016/j.jped.2023.11.007","DOIUrl":"10.1016/j.jped.2023.11.007","url":null,"abstract":"<div><h3>Objective</h3><p>To investigate the relationship between the biopsychosocial environment and eating habits and behaviors that lead to the selection and consumption of certain food from the earliest stages of life. To clarify whether there is an interaction between genetic and epigenetic factors, and how they shape eating habits.</p></div><div><h3>Data source</h3><p>A narrative review based on research in PubMed and Web of Science electronic databases was carried out over the last 10 years, searching the title and summary fields using the keywords Children OR adolescents Feeding Behavior eating OR Dietary Habits OR Eating Behavior OR Eating Habits OR Children obesity.</p></div><div><h3>Data synthesis</h3><p>The generational transmission of eating habits is related to the home, community, and school environments, mainly during the first years of life, and can exert the modulation of habits during all stages of life. During childhood, the family's role in consolidating eating habits is very broad and ranges from choosing foods to prioritizing family meals, including the lifestyle.</p></div><div><h3>Conclusions</h3><p>Eating habits are transmitted from parents to children in different ways: environmental, emotional, social, and educational. In cases of obesity, a greater association of genetic influence can be observed.</p></div>","PeriodicalId":14867,"journal":{"name":"Jornal de pediatria","volume":null,"pages":null},"PeriodicalIF":3.3,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0021755723001547/pdfft?md5=dbe668d14f02697ba16d6ec2f8904607&pid=1-s2.0-S0021755723001547-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139013011","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Diagnosis and treatment of eating disorders in children and adolescents 儿童和青少年饮食失调症的诊断和治疗

IF 3.3 4区医学

Jornal de pediatria Pub Date : 2024-03-01 DOI: 10.1016/j.jped.2023.12.001

Ana Paola Robatto , Carla de Magalhães Cunha , Luiza Amélia Cabus Moreira

{"title":"Diagnosis and treatment of eating disorders in children and adolescents","authors":"Ana Paola Robatto , Carla de Magalhães Cunha , Luiza Amélia Cabus Moreira","doi":"10.1016/j.jped.2023.12.001","DOIUrl":"10.1016/j.jped.2023.12.001","url":null,"abstract":"<div><h3>Objectives</h3><p>To provide a narrative review of the main eating disorders (ED), specifically focusing on children and adolescents. This review also aims to help the pediatrician identify, diagnose, and refer children and adolescents affected by this medical condition and inform them about the multidisciplinary treatment applied to these disorders.</p></div><div><h3>Data source</h3><p>The research was conducted in the Scientific Electronic Library Online (SciELO), Medical Literature Analysis and Retrieval System Online (Medline) databases via PubMed and Embase. Consolidated Guidelines and Guidebooks in the area were also included in the review to support the discussion of ED treatment in childhood and adolescence.</p></div><div><h3>Data synthesis</h3><p>ED are psychiatric condition that usually begins in adolescence or young adulthood but can occur at any time of life, including in childhood, which has been increasingly frequent. Pediatricians are the first professionals to deal with the problem and, therefore, must be well trained in identifying and managing these disorders, which can be severe, and determine physical complications and quality of life of patients and their families.</p></div><div><h3>Conclusion</h3><p>ED has shown an increase in prevalence, as well as a reduction in the age of diagnosed patients, requiring adequate detection and referral by pediatricians. The treatment requires a specialized multidisciplinary team and is generally long-lasting for adequate recovery of affected individuals.</p></div>","PeriodicalId":14867,"journal":{"name":"Jornal de pediatria","volume":null,"pages":null},"PeriodicalIF":3.3,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0021755723001559/pdfft?md5=b941d6abb89adbc82b2eb8d7caab300e&pid=1-s2.0-S0021755723001559-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139051984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Diagnostic utility, disease activity, and disease phenotype correlation of serum ASCA, pANCA, and PR3-ANCA in pediatric inflammatory bowel disease 儿童炎症性肠病中血清ASCA、pANCA和PR3-ANCA的诊断效用、疾病活动性和疾病表型相关性

IF 3.3 4区医学

Jornal de pediatria Pub Date : 2024-03-01 DOI: 10.1016/j.jped.2023.10.005

Jeong Min Kim , Young Min Choi , Seung A Jung , Hye Ran Yang

{"title":"Diagnostic utility, disease activity, and disease phenotype correlation of serum ASCA, pANCA, and PR3-ANCA in pediatric inflammatory bowel disease","authors":"Jeong Min Kim , Young Min Choi , Seung A Jung , Hye Ran Yang","doi":"10.1016/j.jped.2023.10.005","DOIUrl":"10.1016/j.jped.2023.10.005","url":null,"abstract":"<div><h3>Objective</h3><p>This study aimed to evaluate the diagnostic utility, disease activity, and phenotypic association of serum anti-<em>Saccharomyces cerevisiae</em> antibody (ASCA), perinuclear anti-neutrophil cytoplasmic antibody (pANCA), PR3-ANCA, and MPO-ANCA in pediatric patients with inflammatory bowel disease (IBD).</p></div><div><h3>Methods</h3><p>Pediatric patients diagnosed with IBD were recruited and classified as Crohn's disease (CD), ulcerative colitis (UC), and IBD-unclassified (IBD-U) through full investigation. The Paris classification was used to evaluate disease phenotypes of pediatric CD and UC.</p></div><div><h3>Results</h3><p>In all, 229 pediatric patients with IBD (CD 147, UC 53, IBD-U 29) were included. The ASCA IgG seropositivity significantly differed among the three groups (CD 75.4%, UC 17.5%, and IBD-U 60.0%; <em>p</em> < 0.001). PR3-ANCA positive rates were the highest in UC (24.0%), followed by IBD-U (17.6%), and none in CD (<em>p</em> = 0.002); pANCA-positive rates were higher in IBD-U (33.6%), followed by UC (28.0%) than in CD (1.4%) (<em>p</em> < 0.001). Regarding disease phenotype, perianal disease revealed higher serum ASCA IgG titers (median 36.7 U/mL in P1 <em>vs.</em> 25.2 U/mL in P0, <em>p</em> = 0.019). Serum ASCA IgG and IgA cutoff values to distinguish CD were 32.7 (U/mL) and 11.9 (U/mL), respectively, with a specificity of 80.0%.</p></div><div><h3>Conclusion</h3><p>Serological biomarkers of ASCA IgG and IgA were effective for differentiating CD in pediatric IBD patients, and serum pANCA and PR3-ANCA, but not MPO-ANCA, were effective in distinguishing UC and IBD-U. Furthermore, measuring serological titers of ASCA IgG and IgA may help differentiate CD and evaluate the disease activity and phenotype of pediatric IBD in practice.</p></div>","PeriodicalId":14867,"journal":{"name":"Jornal de pediatria","volume":null,"pages":null},"PeriodicalIF":3.3,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0021755723001377/pdfft?md5=eed46449e130fa73dadcdb326389060d&pid=1-s2.0-S0021755723001377-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138444780","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Congenital hyperinsulinism and surgical outcome in a single tertiary center in Brazil 巴西一家三级中心的先天性高胰岛素血症和手术结果。

IF 3.3 4区医学

Jornal de pediatria Pub Date : 2024-03-01 DOI: 10.1016/j.jped.2023.09.005

Raphael Del Roio Liberatore Junior , Isabella Christina Mazzaro Monteiro , Flavio de Oliveira Pileggi , Wellen Cristina Canesin , Lourenço Sbragia

{"title":"Congenital hyperinsulinism and surgical outcome in a single tertiary center in Brazil","authors":"Raphael Del Roio Liberatore Junior , Isabella Christina Mazzaro Monteiro , Flavio de Oliveira Pileggi , Wellen Cristina Canesin , Lourenço Sbragia","doi":"10.1016/j.jped.2023.09.005","DOIUrl":"10.1016/j.jped.2023.09.005","url":null,"abstract":"<div><h3>Objective</h3><p>Congenital hyperinsulinism (CHI) is a heterogeneous genetic disease characterized by increased insulin secretion and causes persistent hypoglycemia in neonates and infants due to dysregulation of insulin secretion by pancreatic β cells. Babies with severe hypoglycemia and for whom medical treatment has been ineffective usually require surgical treatment with near-total pancreatectomy. To evaluate the clinical and surgical aspects affecting survival outcomes in babies diagnosed with CHI in a single tertiary care center.</p></div><div><h3>Methods</h3><p>Retrospective Cohort study involving a single university tertiary center for the treatment of CHI. The authors study the demographics, clinical, laboratory, and surgical outcomes of this casuistic.</p></div><div><h3>Results</h3><p>61 % were female, 39 % male, Birth weight: 3576 g (±313); Age of onset of symptoms: from the 2nd hour of life to 28 days; Time between diagnosis and surgery ranged between 10 and 60 days; Medical clinical treatment, all patients received glucose solution with a continuous glucose infusion and diazoxide. 81 % of the patients used corticosteroids, 77 %. thiazide, 72 % octreotide, 27 % nifedipine; Neurological sequelae during development and growth: 54 % had some degree of delay in neuropsychomotor development, 27 % obesity. Surgery was performed open in 6 and 12 minimally invasive surgery (MIS). Histopathology: 2 focal and 16 diffuse, Length of stay (days) was lower in MIS (<em>p</em> < 0.05). Survival was 100 %.</p></div><div><h3>Conclusions</h3><p>CHI is a rare and difficult-to-manage tumor that must be performed in a multidisciplinary and tertiary center. Most surgical results are good and the laparoscopic approach to disease has been the best choice for patients.</p></div>","PeriodicalId":14867,"journal":{"name":"Jornal de pediatria","volume":null,"pages":null},"PeriodicalIF":3.3,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0021755723001201/pdfft?md5=ef169d0734c97adcd777d7ce17685482&pid=1-s2.0-S0021755723001201-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49690612","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ultra-processed food consumption and children and adolescents’ health 超加工食品消费与儿童和青少年健康。

IF 3.3 4区医学

Jornal de pediatria Pub Date : 2024-03-01 DOI: 10.1016/j.jped.2023.09.006

Samantha Bittencourt Mescoloto , Gabriela Pongiluppi , Semíramis Martins Álvares Domene

{"title":"Ultra-processed food consumption and children and adolescents’ health","authors":"Samantha Bittencourt Mescoloto , Gabriela Pongiluppi , Semíramis Martins Álvares Domene","doi":"10.1016/j.jped.2023.09.006","DOIUrl":"10.1016/j.jped.2023.09.006","url":null,"abstract":"<div><h3>Objectives</h3><p>To present observational studies investigating associations between the consumption of ultra-processed foods and health outcomes in childhood and adolescence.</p></div><div><h3>Data source</h3><p>Observational, cross-sectional, or longitudinal studies were considered, and identified in the Scopus, Web of Science, Pubmed and Scielo databases, without date restrictions.</p></div><div><h3>Data synthesis</h3><p>The most frequent combinations of risk factors in children and adolescents involved an unhealthy diet, with regular consumption of ultra-processed foods to the detriment of a diet based on fresh or minimally-processed foods and insufficient levels of physical activity; records on alcohol and tobacco use were identified. Combined, these practices contribute to the findings that indicate an increase in the prevalence of obesity in children and adolescents and a sedentary lifestyle, with a decrease in physical activity, in addition to representing a risk for the development of chronic non-communicable diseases, such as cardiovascular diseases and periodontal disease in childhood and adolescence.</p></div><div><h3>Conclusions</h3><p>The present study maps the current literature on the topic and indicates the direction of the approach for health promotion and prevention of NCDs in children and adolescents. Among the different risk factors that negatively affect the full development of this population, frequently eating breakfast and practicing physical activity is most strongly associated with a lower consumption of ultra-processed foods and should be part of an integrated approach to promoting eating practices that favor the reduction of diseases also in adult life.</p></div>","PeriodicalId":14867,"journal":{"name":"Jornal de pediatria","volume":null,"pages":null},"PeriodicalIF":3.3,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0021755723001213/pdfft?md5=8670587b6609d6a7f0d816e9e3d702e1&pid=1-s2.0-S0021755723001213-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49690613","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Marketing and child feeding 营销和儿童营养。

IF 3.3 4区医学

Jornal de pediatria Pub Date : 2024-03-01 DOI: 10.1016/j.jped.2023.09.013

Kátia Galeão Brandt , Giselia Alves Pontes da Silva

{"title":"Marketing and child feeding","authors":"Kátia Galeão Brandt , Giselia Alves Pontes da Silva","doi":"10.1016/j.jped.2023.09.013","DOIUrl":"10.1016/j.jped.2023.09.013","url":null,"abstract":"<div><h3>Objective</h3><p>To carry out a narrative review on the use of marketing strategies in child nutrition, as well as potential implications for health professionals and children.</p></div><div><h3>Data source</h3><p>Searches were carried out on the PubMed, SciELO, and Google platforms, using the terms “child nutrition” or “industrialized baby food” or “infant formula” or “breast milk” or “breastfeeding” and “marketing”, with original articles, review articles, institutional reports, institutional position documents and websites considered relevant to the topic being analyzed.</p></div><div><h3>Data synthesis</h3><p>Children's food marketing started with the industrialization of food and the resulting actions aimed at increasing sales and meeting commercial interests. Since its inception to the present, infant formulas have been the most widely used products, which has impacted breastfeeding practices. International and national institutions, that care for children's health, are searching for strategies to limit the abusive marketing of industrialized children's foods. Marketing strategies interfere with medical knowledge and actions, potentially influencing the guidance provided by pediatricians to families, and finally, compromising healthy eating practices at a critical period in life, with possible long-term effects.</p></div><div><h3>Conclusions</h3><p>Health professionals, especially pediatricians, must provide the best care for children and families, and need to maintain the search for quality scientific information, not influenced by conflicts of interest. Updated and critical knowledge on the part of healthcare professionals can curb marketing strategies that aim to influence their actions.</p></div>","PeriodicalId":14867,"journal":{"name":"Jornal de pediatria","volume":null,"pages":null},"PeriodicalIF":3.3,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0021755723001316/pdfft?md5=efe6351adcb02c749a2b000d74654ece&pid=1-s2.0-S0021755723001316-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71423828","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

What causes obesity in children and adolescents? 是什么导致儿童和青少年肥胖？

IF 3.3 4区医学

Jornal de pediatria Pub Date : 2024-03-01 DOI: 10.1016/j.jped.2023.09.011

Carlos Alberto Nogueira-de-Almeida , Virginia Resende Silva Weffort , Fábio da V. Ued , Ivan S. Ferraz , Andrea A. Contini , Edson Zangiacomi Martinez , Luiz A. Del Ciampo

{"title":"What causes obesity in children and adolescents?","authors":"Carlos Alberto Nogueira-de-Almeida , Virginia Resende Silva Weffort , Fábio da V. Ued , Ivan S. Ferraz , Andrea A. Contini , Edson Zangiacomi Martinez , Luiz A. Del Ciampo","doi":"10.1016/j.jped.2023.09.011","DOIUrl":"10.1016/j.jped.2023.09.011","url":null,"abstract":"<div><h3>Objective</h3><p>To present the different aspects that may be involved in the genesis and maintenance of obesity in children and adolescents.</p></div><div><h3>Data source</h3><p>Narrative review of articles published in the PubMed, Scielo, Lilacs, Scopus and Google Scholar databases, using the search terms: overweight, obesity, pre-conception, prenatal, infants, schoolchildren, children, and adolescents. The search was conducted in studies written in Portuguese, English and Spanish, including narrative, integrative or systematic reviews, meta-analyses, cross-sectional, case-control and cohort studies, published between 2003 and 2023.</p></div><div><h3>Data synthesis</h3><p>A total of 598 studies were initially screened and 60 of them, which showed the main biopsychosocial aspects related to greater risks of excessive adiposity in the pediatric age, were included in the review. The data were presented taking into account the incidence of risk factors and their consequences in six periods: pre-conception, pre-natal, infant, preschool, school age, and adolescence.</p></div><div><h3>Conclusions</h3><p>The causal factors described in the scientific literature that have been shown to be related to obesity in childhood and adolescence are presented.</p></div>","PeriodicalId":14867,"journal":{"name":"Jornal de pediatria","volume":null,"pages":null},"PeriodicalIF":3.3,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0021755723001274/pdfft?md5=9ae23c690d6401cb12bae4b4a888ac73&pid=1-s2.0-S0021755723001274-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71423829","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Public health implications of replacing screen time with physical activity and sleep in Brazilian children 巴西儿童以体育活动和睡眠取代屏幕时间对公共卫生的影响。

IF 3.3 4区医学

Jornal de pediatria Pub Date : 2024-03-01 DOI: 10.1016/j.jped.2023.11.004

Ryan D. Burns

引用次数: 0

Child feeding and nutrition: a contemporary view 儿童喂养与营养：当代视角

IF 3.3 4区医学

Jornal de pediatria Pub Date : 2024-03-01 DOI: 10.1016/j.jped.2024.01.001

Crésio de Aragão Dantas Alves , Giselia Alves Pontes da Silva

引用次数: 0

Bone and joint infection complicated with sepsis in neonates and infants under three months of age 新生儿和三个月以下婴儿的骨关节感染并发败血症。

IF 3.3 4区医学

Jornal de pediatria Pub Date : 2024-03-01 DOI: 10.1016/j.jped.2023.09.003

Yao Liu , Kai Zhao , Ya Liu , Yu-Han Sun , Meng-Xia Li , Min Yu , Lun-Qing Zhu , Xiao-Dong Wang

{"title":"Bone and joint infection complicated with sepsis in neonates and infants under three months of age","authors":"Yao Liu , Kai Zhao , Ya Liu , Yu-Han Sun , Meng-Xia Li , Min Yu , Lun-Qing Zhu , Xiao-Dong Wang","doi":"10.1016/j.jped.2023.09.003","DOIUrl":"10.1016/j.jped.2023.09.003","url":null,"abstract":"<div><h3>Objective</h3><p>Studies focusing on bone and joint infections (BJIs) in young infants are rare. Some cases of BJI are accompanied by sepsis. This study aimed to identify the clinical and bacteriological features of sepsis in neonates and young infants with BJIs.</p></div><div><h3>Methods</h3><p>Neonates and infants younger than 3 months diagnosed with BJI in the present institution from 2014 to 2021 were retrospectively reviewed. Patient characteristics, clinical data, and outcomes were documented and compared between those with and without sepsis.</p></div><div><h3>Results</h3><p>Twenty-five patients with a mean age of 34.8 days were included. Nine BJI cases had concomitant sepsis (group A), and 16 had BJI without sepsis (group B). Within group A, staphylococcus aureus was the major pathogenic germ (5 cases, of which 4 were of the methicillin-resistant staphylococcus aureus (MRSA) type). There was no statistical difference in male-to-female ratio, age, history of hospitalization, anemia, birth asphyxia, peripheral leukocyte counts, C-reactive protein on admission, and sequelae between groups. Univariate analyses indicated a significant difference in the incidence of septic arthritis (SA) combined with osteomyelitis (OM) (88.9% vs 37.5%), congenital deformities (44.4% vs 0%), and mean duration of symptoms (2.83 days vs 9.21 days) in comparisons between groups A and B.</p></div><div><h3>Conclusion</h3><p>Staphylococcus aureus is the main pathogenic bacteria in BJI cases complicated with sepsis in neonates and young infants. Among infants younger than 3 months diagnosed with BJI, those with concurrent SA and OM, MRSA infection, or congenital deformities are more likely to develop sepsis.</p></div>","PeriodicalId":14867,"journal":{"name":"Jornal de pediatria","volume":null,"pages":null},"PeriodicalIF":3.3,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S002175572300116X/pdfft?md5=bc0b98141a19a35896b131e11cc1bcdb&pid=1-s2.0-S002175572300116X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41201611","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0