Jornal de pediatria最新文献

Clinical features of dengue-associated myositis in children: a retrospective study. 儿童登革热相关肌炎的临床特征：一项回顾性研究

IF 2.5 4区医学

Jornal de pediatria Pub Date : 2026-05-06 DOI: 10.1016/j.jped.2026.101549

Raquel O Birne, Marianna A Neri, Camille A Rossetti, Mila O Sena, Laís P R Duarte, Luji I Takenami, Juliana B Goulardins, Marcos A Matos

{"title":"Clinical features of dengue-associated myositis in children: a retrospective study.","authors":"Raquel O Birne, Marianna A Neri, Camille A Rossetti, Mila O Sena, Laís P R Duarte, Luji I Takenami, Juliana B Goulardins, Marcos A Matos","doi":"10.1016/j.jped.2026.101549","DOIUrl":"10.1016/j.jped.2026.101549","url":null,"abstract":"<p><strong>Objectives: </strong>The presentation of dengue as infectious myositis is considered an atypical and often underrecognized manifestation. This study aimed to characterize the clinical features and outcomes of pediatric patients diagnosed with dengue-associated infectious myositis, to delineate their sociodemographic profiles at the time of diagnosis, and to evaluate their laboratory findings and clinical outcomes.</p><p><strong>Methods: </strong>The authors conducted a retrospective observational study in the pediatric department of a tertiary care hospital in the state of Bahia, Brazil, including patients up to 14 years who were admitted with clinical features of infectious myositis and laboratory-confirmed dengue infection between January 2022 and July 2024. Sociodemographic characteristics, clinical manifestations, laboratory parameters and outcomes were analyzed.</p><p><strong>Results: </strong>Data from 176 patients were analyzed. A higher incidence was observed among male patients (68.8%), with most cases occurring during the winter season (56.25%). The mean age was 9.25 ± 3.22 years. Fever was the most frequent symptom (96%), followed by myalgia (89.2%). Calf pain was reported in 69.3% of cases. Regarding creatine phosphokinase (CK) levels, 46% of patients had values between 1000-5000 U/L, while 17% presented with CK > 5000 U/L at admission. None of the patients developed acute kidney injury or died.</p><p><strong>Conclusions: </strong>Dengue-associated myositis exhibited a benign clinical course in this symptomatic pediatric cohort. However, these findings suggest that clinical and laboratory parameters may support a risk-based clinical approach to patient monitoring and management; prospective studies are needed to validate risk stratification strategies.</p>","PeriodicalId":14867,"journal":{"name":"Jornal de pediatria","volume":" ","pages":"101549"},"PeriodicalIF":2.5,"publicationDate":"2026-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147723055","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Dietary selenium intake and asthma in US children and adolescents. 膳食硒摄入量与美国儿童和青少年哮喘的关系

IF 2.5 4区医学

Jornal de pediatria Pub Date : 2026-05-06 DOI: 10.1016/j.jped.2026.101551

Lingyu Li, Shuai Wang, Hongyan Wei, Changcheng Sun

{"title":"Dietary selenium intake and asthma in US children and adolescents.","authors":"Lingyu Li, Shuai Wang, Hongyan Wei, Changcheng Sun","doi":"10.1016/j.jped.2026.101551","DOIUrl":"10.1016/j.jped.2026.101551","url":null,"abstract":"<p><strong>Objective: </strong>Evidence concerning total dietary selenium intake in the US pediatric population remains sparse and inconsistent. This study employs a nationally representative dataset to investigate the association between selenium intake and asthma prevalence, addressing this critical knowledge gap.</p><p><strong>Method: </strong>The National Health and Nutrition Examination Survey (NHANES) (2011-2020) furnished data on asthmatic individuals aged < 20 years with quantified dietary selenium intake. Utilizing rigorous statistical methodologies - multivariable logistic regression, restricted cubic spline (RCS) modeling, and subgroup analyses - the authors evaluated the selenium-asthma association.</p><p><strong>Results: </strong>In this study encompassing 7780 pediatric participants, multivariable logistic regression with comprehensive covariate adjustment revealed progressively higher asthma risk with increasing selenium exposure. Compared to the lowest intake tertile (Q1: ≤ 73.3 mg/day), adjusted ORs were 1.15 (95% CI: 0.98-1.35; p = 0.082) for Q2 (73.4-112.6 mg/day) and 1.24 (95% CI: 1.00-1.54; p = 0.048) for Q3 (≥ 112.7 mg/day). Subsequent restricted cubic spline modeling quantitatively established a significant dose-response relationship (p = 0.042) between dietary selenium levels and asthma risk.</p><p><strong>Conclusion: </strong>Dietary selenium intake demonstrated a significant dose-dependent association with asthma prevalence among US pediatric populations.</p>","PeriodicalId":14867,"journal":{"name":"Jornal de pediatria","volume":" ","pages":"101551"},"PeriodicalIF":2.5,"publicationDate":"2026-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147772101","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Quantitative lung ultrasound to understand pathophysiology and guide surfactant therapy in neonates with meconium aspiration 定量肺超声了解新生儿胎粪吸入性病理生理，指导表面活性剂治疗。

IF 2.5 4区医学

Jornal de pediatria Pub Date : 2026-05-01 Epub Date: 2026-04-27 DOI: 10.1016/j.jped.2026.101550

Daniele De Luca

引用次数: 0

Development of a childhood food and nutrition security observatory: experience of an interinstitutional initiative in the state of São Paulo 儿童食品和营养安全观察站的发展：<s:1>圣保罗州机构间倡议的经验。

IF 2.5 4区医学

Jornal de pediatria Pub Date : 2026-05-01 Epub Date: 2026-04-25 DOI: 10.1016/j.jped.2026.101547

Karina Viani , Marcos Sakurada , Aracelia Costa , Mauro Fisberg , Priscila Maximino , Raul Cutait

{"title":"Development of a childhood food and nutrition security observatory: experience of an interinstitutional initiative in the state of São Paulo","authors":"Karina Viani , Marcos Sakurada , Aracelia Costa , Mauro Fisberg , Priscila Maximino , Raul Cutait","doi":"10.1016/j.jped.2026.101547","DOIUrl":"10.1016/j.jped.2026.101547","url":null,"abstract":"<div><h3>Objective</h3><div>To describe the development of the FIESP Observatory for Childhood Food and Nutrition Security (FNS), a digital platform designed to organize and integrate public data on children aged 0 to 10 years in the state of São Paulo, Brazil.</div></div><div><h3>Methods</h3><div>This descriptive study involved three main stages: (1) a literature review and mapping of national and international observatories on health, nutrition, and childhood to identify best practices and gaps; (2) establishment of an expert committee of professionals in nutrition, public health, and public policies to guide indicator selection and ensure technical quality; and (3) technical development of the platform, including automated data extraction, processing, and integration into thematic dashboards. Public databases from official sources were incorporated, structured across six thematic axes: demographic, socioeconomic, FNS policies, nutritional, health, and educational profiles.</div></div><div><h3>Results</h3><div>The observatory was launched in May 2025 and made freely available online. It features six interactive panels and a “Your City” dashboard that consolidates key indicators for each municipality in São Paulo. Since its launch, it has received >9600 visits, with 4755 active users. The tool enables segmented analyses by geography, time, and demographics, providing evidence to support policy design and monitoring.</div></div><div><h3>Conclusions</h3><div>The Observatory represents an innovative and scalable model for consolidating childhood FNS data. By offering free, intuitive, and continuously updated access to official indicators, it supports policymakers, researchers, and civil society in addressing childhood food insecurity and advancing the right to adequate and healthy food.</div></div>","PeriodicalId":14867,"journal":{"name":"Jornal de pediatria","volume":"102 3","pages":"Article 101547"},"PeriodicalIF":2.5,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147673573","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Assessment of abdominal symptoms and intestinal inflammation in children and adolescents with cystic fibrosis without highly effective modulator therapy. 无高效调节剂治疗的儿童和青少年囊性纤维化患者腹部症状和肠道炎症的评估

IF 2.5 4区医学

Jornal de pediatria Pub Date : 2026-04-25 DOI: 10.1016/j.jped.2026.101552

Gabriel Cezar Dos Santos, Lorenna Cristina Montera, Lívia Moreira Genaro, Beatriz Alves Guerra Rodrigues, Raquel Franco Leal, Antonio Fernando Ribeiro, Jose Dirceu Ribeiro, Elizete Aparecida Lomazi

{"title":"Assessment of abdominal symptoms and intestinal inflammation in children and adolescents with cystic fibrosis without highly effective modulator therapy.","authors":"Gabriel Cezar Dos Santos, Lorenna Cristina Montera, Lívia Moreira Genaro, Beatriz Alves Guerra Rodrigues, Raquel Franco Leal, Antonio Fernando Ribeiro, Jose Dirceu Ribeiro, Elizete Aparecida Lomazi","doi":"10.1016/j.jped.2026.101552","DOIUrl":"https://doi.org/10.1016/j.jped.2026.101552","url":null,"abstract":"<p><strong>Objective: </strong>Cystic fibrosis (CF) is a rare genetic disease caused by mutations in the CFTR gene, resulting in a dysfunctional protein that affects various systems in the body, including the gastrointestinal (GI) tract. The changes caused by CF in the GI tract include dysmotility, dysbiosis, intestinal inflammation, and abdominal symptoms such as pain, altered bowel habits, and distension, which are frequent in people with CF. This study aims to establish the prevalence of these complaints in children with CF and investigate associations between symptoms, clinical conditions, and markers of intestinal inflammation.</p><p><strong>Methods: </strong>Twenty-two pediatric patients with a genetic diagnosis of CF, followed at a Brazilian reference center, were included. Methods involved a systematic assessment of gastrointestinal symptoms using a questionnaire, biochemical analysis of fecal calprotectin (FC) as a marker of intestinal inflammation, and collection of clinical, anthropometric, laboratory, and imaging data from medical records.</p><p><strong>Results: </strong>86.3% (n = 19) of participants showed elevated FC levels (> 50 gt; 50 mcg/g), indicating a high prevalence of intestinal inflammation. The most common abdominal symptoms were pain and flatulence, present in about half of the patients. No significant associations were observed between FC levels and clinical or symptomatic variables.</p><p><strong>Conclusion: </strong>There is a high prevalence of intestinal inflammation and abdominal symptoms in this sample of Brazilian children with CF, highlighting the importance of systematically investigating these symptoms.</p>","PeriodicalId":14867,"journal":{"name":"Jornal de pediatria","volume":" ","pages":"101552"},"PeriodicalIF":2.5,"publicationDate":"2026-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147772107","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Infrared thermography in the assessment of brown and white adipose tissue in children with different nutritional states 红外热成像在评估不同营养状态儿童棕色和白色脂肪组织中的作用。

IF 2.5 4区医学

Jornal de pediatria Pub Date : 2026-03-01 Epub Date: 2026-01-10 DOI: 10.1016/j.jped.2025.101498

Gisele Bailich , Paulo Roberto Santos Lopes , Danubia da Cunha de Sá-Caputo , Alessandro Sartório , Gabriela Peixe , Mario Bernardo Filho , André Everton de Freitas , Anelise Sonza

{"title":"Infrared thermography in the assessment of brown and white adipose tissue in children with different nutritional states","authors":"Gisele Bailich , Paulo Roberto Santos Lopes , Danubia da Cunha de Sá-Caputo , Alessandro Sartório , Gabriela Peixe , Mario Bernardo Filho , André Everton de Freitas , Anelise Sonza","doi":"10.1016/j.jped.2025.101498","DOIUrl":"10.1016/j.jped.2025.101498","url":null,"abstract":"<div><h3>Objective</h3><div>To evaluate brown adipose tissue (BAT) and white adipose tissue using Infrared Thermography (IRT) in children with different nutritional statuses and correlate findings with anthropometric variables.</div></div><div><h3>Methods</h3><div>This cross-sectional observational study assessed body composition via bioelectrical impedance (BIA), skin temperature (supraclavicular and abdominal) through IRT, and anthropometric variables such as neck (NC), waist (WC), and hip (HC) circumferences. Calculations included waist-to-hip ratio (WHR) and conicity index (CI). Statistical analyses were performed in SPSS 20.0, with normality checked by the Shapiro-Wilk and homogeneity by Levene tests. Groups (eutrophic, overweight, obese) were compared using Pearson's Chi-square for categorical variables, Kruskal-Wallis, and ANOVA tests for quantitative data. Correlations were analyzed using Spearman's method. The significance level was set at p ≤ 0.05.</div></div><div><h3>Results</h3><div>Of 160 participants, 116 children were analyzed (eutrophic: N = 58; overweight: N = 26; obese: N = 32). Significant differences were noted between the eutrophic and obese groups. Supraclavicular temperature negatively correlated with BIA variables (total body water, fat-free mass, body fat percentage).</div></div><div><h3>Conclusions</h3><div>IRT demonstrated inverse correlations between BAT temperature and BMI, NC, WC, and HC, underscoring its potential in obesity risk analysis. IRT also offers quantitative assessments of BAT activity and may estimate body fat percentages, suggesting its relevance for monitoring adipose tissue function and metabolic effects of physical exercise.</div></div>","PeriodicalId":14867,"journal":{"name":"Jornal de pediatria","volume":"102 2","pages":"Article 101498"},"PeriodicalIF":2.5,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145862986","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Unveiling autism spectrum disorder for the pediatrician 为儿科医生揭开自闭症谱系障碍的面纱。

IF 2.5 4区医学

Jornal de pediatria Pub Date : 2026-03-01 Epub Date: 2025-11-03 DOI: 10.1016/j.jped.2025.101458

Marcio Moacyr Vasconcelos , Luciana Gonçalves Azevedo Vasconcelos , Adriana Rocha Brito

{"title":"Unveiling autism spectrum disorder for the pediatrician","authors":"Marcio Moacyr Vasconcelos , Luciana Gonçalves Azevedo Vasconcelos , Adriana Rocha Brito","doi":"10.1016/j.jped.2025.101458","DOIUrl":"10.1016/j.jped.2025.101458","url":null,"abstract":"<div><h3>Objectives</h3><div>To review the state of the art in autism spectrum disorder (ASD), including its etiologic puzzle, clinical features, pathophysiologic mechanisms, differential diagnosis, and therapeutic management.</div></div><div><h3>Data sources</h3><div>A search for papers published over the past 10 years in the databases PubMed-MEDLINE, Cochrane Library, and SCIELO was performed using the following terms: “autism” and “clinical features”, “differential diagnosis”, “pathophysiology”, or “management”. The search yielded 3240, 590, 6904, and 5023 papers, respectively. A total of 120 most relevant papers were selected based on their title and abstract content.</div></div><div><h3>Data synthesis</h3><div>The current prevalence of ASD is 1 in every 31 eight-year-old children. A genetic defect is found in 10–20% of individuals with ASD. Environmental risk factors that increase the likelihood of ASD include advanced parental age and maternal health conditions. Epigenetic mechanisms may play a crucial role in the interplay between genetic and environmental factors in the pathogenesis of ASD. In addition to language delay, pediatricians should monitor and screen for several early signs of ASD. Differential diagnosis is complex because several neurodevelopmental conditions show clinical features that overlap with ASD. Medications may be used to treat comorbid conditions.</div></div><div><h3>Conclusions</h3><div>Management is based on a multidisciplinary team, and pediatricians are in a unique position to coordinate this team, given the trustworthy relationship they have with patients and their families.</div></div>","PeriodicalId":14867,"journal":{"name":"Jornal de pediatria","volume":"102 ","pages":"Article 101458"},"PeriodicalIF":2.5,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145307823","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The utilization of oral feeding in pediatric pancreatitis: a randomized controlled study 口服喂养在小儿胰腺炎中的应用：一项随机对照研究。

IF 2.5 4区医学

Jornal de pediatria Pub Date : 2026-03-01 Epub Date: 2026-02-06 DOI: 10.1016/j.jped.2026.101501

Yan Han, Hong Zhao, Linchen Fu, Xinyi Jia, Xiao Du, Liqun Zhou, Jindan Yu, Jie Chen, Jingan Lou

{"title":"The utilization of oral feeding in pediatric pancreatitis: a randomized controlled study","authors":"Yan Han, Hong Zhao, Linchen Fu, Xinyi Jia, Xiao Du, Liqun Zhou, Jindan Yu, Jie Chen, Jingan Lou","doi":"10.1016/j.jped.2026.101501","DOIUrl":"10.1016/j.jped.2026.101501","url":null,"abstract":"<div><h3>Objective</h3><div>There is increasing awareness of the benefits of early nutritional intervention in children with acute pancreatitis (AP). This study aims to compare oral feeding with NG feeding in mild to moderately severe AP patients.</div></div><div><h3>Methods</h3><div>A single-center, prospective, randomized controlled trial was conducted from September 2021 to August 2024. The participants were randomly assigned to the oral feeding group or the NG feeding group. The primary outcomes were the duration of AP-related pain, tolerance rate, and changes in weight.</div></div><div><h3>Results</h3><div>A total of 56 pediatric patients were enrolled, of whom 48 patients (24 in each group) were included in the final analysis. There were no significant differences in baseline characteristics or etiological analysis results between the two groups. The median duration of abdominal pain after admission was 3 days in both groups (<em>p</em> = 0.104); no difference was found in the tolerance rate between the 2 cohorts (<em>p</em> = 0.489). There were no significant differences in weight change between the two groups at discharge or at 1 week or 5 weeks after discharge (<em>p</em> = 0.658, 0.502, and 0.927, respectively), and both groups presented slight increases in weight at 5 weeks post-discharge. Four patients in the NG group developed complications, while no complications were observed in the ORAL group (<em>p</em> = 0.109).</div></div><div><h3>Conclusions</h3><div>Oral feeding is effective for nutritional therapy in children with mild to moderately severe AP, reducing the number of invasive procedures, without significant adverse effects.</div></div>","PeriodicalId":14867,"journal":{"name":"Jornal de pediatria","volume":"102 2","pages":"Article 101501"},"PeriodicalIF":2.5,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146096892","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Transition to adolescence in neurodevelopmental disorders: challenges and clinical perspectives 神经发育障碍的青春期过渡：挑战和临床观点。

IF 2.5 4区医学

Jornal de pediatria Pub Date : 2026-03-01 Epub Date: 2025-10-24 DOI: 10.1016/j.jped.2025.101463

Eduardo Jorge Custódio da Silva , Evelyn Eisenstein

引用次数: 0

Impact of electrocardiogram monitoring on the frequency of tracheal intubation at birth 出生时心电图监测对气管插管频率的影响。

IF 2.5 4区医学

Jornal de pediatria Pub Date : 2026-03-01 Epub Date: 2026-02-08 DOI: 10.1016/j.jped.2026.101504

Thalles de Souza Freire, Mandira Daripa Kawakami, Maria Fernanda de Almeida, Ruth Guinsburg

{"title":"Impact of electrocardiogram monitoring on the frequency of tracheal intubation at birth","authors":"Thalles de Souza Freire, Mandira Daripa Kawakami, Maria Fernanda de Almeida, Ruth Guinsburg","doi":"10.1016/j.jped.2026.101504","DOIUrl":"10.1016/j.jped.2026.101504","url":null,"abstract":"<div><h3>Objective</h3><div>To determine whether the use of an electrocardiogram monitor in newborns receiving positive pressure ventilation (PPV) at birth affects the frequency of tracheal intubation in the delivery room.</div></div><div><h3>Methods</h3><div>Retrospective cohort of liveborn infants without congenital anomalies, with gestational age (GA) ≥ 23 weeks and birth weight ≥ 400 <em>g</em> who received PPV at birth, from 2014 to 2022. Newborns were stratified by GA (< 34 or ≥ 34 weeks) and by use or non-use of an electrocardiogram monitor during resuscitation. Logistic regression was used to assess the association between electrocardiogram monitoring and outcomes of interest for each GA group.</div></div><div><h3>Results</h3><div>Among 5622 live births, 516 met the inclusion criteria; 224 (43 %) were monitored, and 292 (57 %) were not. The frequency of tracheal intubation was similar between monitored and non-monitored groups: ≥ 34 weeks - 13 % vs. 14 %; < 34 weeks - 43 % vs. 43 %. Electrocardiogram monitoring increased the odds of initiating PPV with a face mask ≥ 60 seconds after birth by 2.45-fold (95 % CI: 1.08–5.54) for GA ≥ 34 weeks and by 2.72-fold (95 % CI: 1.13–6.59) for GA < 34 weeks, after adjustment for umbilical cord clamping time, year of birth, and birth weight.</div></div><div><h3>Conclusion</h3><div>Electrocardiogram monitor use did not reduce the frequency of tracheal intubation and was associated with delayed initiation of PPV with a face mask.</div></div>","PeriodicalId":14867,"journal":{"name":"Jornal de pediatria","volume":"102 2","pages":"Article 101504"},"PeriodicalIF":2.5,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146096866","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0