Jornal de pediatria最新文献

{"title":"Predictive value of clinical indicators in children with community-acquired pneumonia complicated with Kawasaki disease","authors":"Yuanhui Duan,&nbsp;Yuexu Ou,&nbsp;Xiaoming Gan,&nbsp;Jieling Li,&nbsp;Jie Cao","doi":"10.1016/j.jped.2025.101424","DOIUrl":"10.1016/j.jped.2025.101424","url":null,"abstract":"<div><h3>Objective</h3><div>This study aimed to investigate the predictive value of clinical indicators in community-acquired pneumonia (CAP) complicated with Kawasaki disease (KD).</div></div><div><h3>Methods</h3><div>A retrospective analysis was conducted on the clinical data of inpatients with KD (39 cases), CAP (40 cases), and CAP complicated with KD (CAPKD, 32 cases) at the Children's Hospital of Chongqing Medical University from February 2021 to October 2022. The clinical indicators examined included serum cytokines (IL-2, IL-4, IL-6, IL-10, IL-17A, TNF-α, IFN-γ), White Blood Cell (WBC), Neutrophilic granulocyte percentage(NEU%), blood platelet(PLT), Red Blood Cell (RBC), Hemoglobin(Hb), erythrocyte sedimentation rate(ESR), C-reactive protein(CRP), procalcitonin(PCT), alanine aminotransferase(ALT), alkaline phosphatase(ALP), Gamma-glutamyl transferase (γ-GT), Aspartate aminotransferase (AST), albumin(Alb), Lactate dehydrogenase (LDH), globulin(Glb), and Total Protein(TP) in patients with KD, CAP, and CAPKD were compared.</div></div><div><h3>Results</h3><div>The present findings showed that IL-6 &gt; 55.4pg/mL, IL-10 &gt; 9.15pg/mL, PCT &gt; 0.19ng/mL, and ALT &gt; 22.5 U/L were important predictors of CAPKD. Additionally, Hb &gt; 103.5 g /L, and TP &gt; 63.85 g/L have predictive values for CAP without KD. The authors also observed a positive correlation between PCT and IL-6, IL-10. However, Hb and TP were negatively correlated with IL-6 and IL-10.</div></div><div><h3>Conclusion</h3><div>From the perspective of cytokine levels, IL-6 &gt; 55.4 pg/mL and IL-10 &gt; 9.15 pg/mL have important predictive values for CAPKD.</div></div>","PeriodicalId":14867,"journal":{"name":"Jornal de pediatria","volume":"101 5","pages":"Article 101424"},"PeriodicalIF":2.5,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144816707","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of the COVID-19 pandemic on the incidence of acute mastoiditis in a tertiary reference children’s hospital in Brazil","authors":"Hemily Izabel Alves Neves MD ,&nbsp;Joel Lavinsky MD, PhD ,&nbsp;Luana Vieira Margheti MD ,&nbsp;Mauricio Schneider Miura MD, PhD ,&nbsp;Patrícia Barcelos Ogando MD, MsC ,&nbsp;Marcelo Assis Moro da Rocha Filho MD ,&nbsp;Jose Faibes Lubianca Neto MD, PhD","doi":"10.1016/j.jped.2025.05.003","DOIUrl":"10.1016/j.jped.2025.05.003","url":null,"abstract":"<div><h3>Objectives</h3><div>To compare the incidence of AM hospitalizations and complications across three periods: pre-pandemic, pandemic, and post-pandemic. Additionally, the study aims to evaluate associations with patient age, need for surgical intervention, antibiotic therapy, and isolated etiological agents.</div></div><div><h3>Methods</h3><div>This retrospective cohort study reviewed pediatric charts from three 22-month periods: pre-pandemic (P1), pandemic (P2), and post-pandemic (P3). These periods were compared in terms of case numbers, presence and severity of AM complications, patient demographics (age and sex), and treatment approaches.</div></div><div><h3>Results</h3><div>A total of 9 AM cases were recorded in (P1), 5 in the (P2), and 25 in (P3). This represents a 25.5 % reduction in AM incidence during the pandemic compared to the pre-pandemic period, though this was not statistically significant (<em>p</em> = 0.8027). However, a significant 103.3 % increase in AM incidence was noted between the pre- and post-pandemic periods (<em>p</em> = 0.0322). No significant differences were found among periods regarding age, sex, complications, case severity, surgical intervention, antibiotic duration, or length of hospitalization.</div></div><div><h3>Conclusion</h3><div>Although AM incidence slightly declined during the pandemic, the post-pandemic period showed a significant rise in the incidence of cases compared to pre-pandemic values.</div></div>","PeriodicalId":14867,"journal":{"name":"Jornal de pediatria","volume":"101 5","pages":"Article 101415"},"PeriodicalIF":2.5,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144215904","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"X-ray is not inferior to CT in terms of F1 score in the diagnosis of foreign body aspiration: a recall, precision and F1 score performance analysis based on bronchoscopically proven cases","authors":"Fatma Sarac,&nbsp;Mehmet Yazici","doi":"10.1016/j.jped.2025.101430","DOIUrl":"10.1016/j.jped.2025.101430","url":null,"abstract":"<div><h3>Objective</h3><div>In this study, we aimed to evaluate the diagnostic accuracy of X-ray and CT by using the F1 score with its non-inferiority margin in patients who underwent bronchoscopy with suspected diagnoses of foreign body aspiration (FBA).</div></div><div><h3>Methods</h3><div>All children aged under 18 who underwent bronchoscopy with suspected diagnoses of FBA between June 2020 and December 2023 were included. The patient’s medical records were examined retrospectively.</div></div><div><h3>Results</h3><div>A total of 310 patients were included. Foreign bodies were most frequently located in the right main bronchus (47.52 %). The bronchoscopy (-) rate was 18 % in patients who had X-ray (+), 24 % in those who had CT (+), and 15 % in those who had X-ray (+) and CT (+). Chest x-rays were found to exhibit 42 % sensitivity, 74 % specificity, a positive predictive value (PPV) of 61 %, a negative predictive value (NPV) of 51 %, accuracy of 66 %, precision: 0.63, recall: 0.82, and F1 score: 0.71. Analysis showed that CT exhibited 82 % sensitivity, 37 % specificity, a PPV of 75 %, NPV of 47 %, an accuracy rate of 69 %, precision: 0.83, recall: 0.76, and F1 score: 0.79. In the present study, the diagnostic F1 score was calculated as 0.79 for CT and 0.71 for X-ray.</div></div><div><h3>Conclusion</h3><div>Despite a negative bronchoscopy rate of 34.83 % in this study, since the authors observed no severe complications or mortality, the authors recommend that it be performed on all patients with suspected foreign body aspiration. When a 10 % non-inferiority margin was applied, X-ray was found to be not inferior to CT in terms of F1 score.</div></div>","PeriodicalId":14867,"journal":{"name":"Jornal de pediatria","volume":"101 5","pages":"Article 101430"},"PeriodicalIF":2.5,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144816710","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy and safety of using Elexacaftor/Tezacaftor/Ivacaftor in the treatment of children with cystic fibrosis: real-world evidence from Brazil","authors":"Guilherme da Silva Martins ,&nbsp;Carolina Rambo ,&nbsp;Gabriela Spessatto ,&nbsp;Maitê Milagres Saab ,&nbsp;Bruno Hernandes David João ,&nbsp;Aline Didoni Fajardo ,&nbsp;Juliana Gonçalves Primon ,&nbsp;Thalita Gonçalves Picciani ,&nbsp;Roberta Corrêa da Cunha ,&nbsp;Herberto José Chong-Neto ,&nbsp;Carlos Roberto Lebarbenchon Massignan ,&nbsp;Luiz Vicente Ribeiro Ferreira da Silva-Filho ,&nbsp;Carlos Antônio Riedi ,&nbsp;Nelson Augusto Rosário Filho ,&nbsp;Débora Carla Chong-Silva","doi":"10.1016/j.jped.2025.05.007","DOIUrl":"10.1016/j.jped.2025.05.007","url":null,"abstract":"<div><h3>Objective</h3><div>Cystic fibrosis (CF) treatment has evolved significantly with the development of CFTR modulators, particularly elexacaftor/tezacaftor/ivacaftor (ETI). This study aimed to evaluate in a real-life context, the efficacy, safety and tolerability of ETI in children and adolescents with CF at a national reference center in Brazil.</div></div><div><h3>Methods</h3><div>A cohort of 39 patients (mean age: 11.7 years) who had been using ETI for at least three months were evaluated. Anthropometric data, pulmonary function, sweat chloride concentration, pulmonary exacerbations, antibiotic use, and liver function were assessed over a follow-up period of up to 17 months.</div></div><div><h3>Results</h3><div>Significant improvements were observed in weight Z-score at three months (<em>p</em> = 0.046) and six months (<em>p</em> = 0.018), as well as absolute weight gain (<em>p</em> &lt; 0.001). Height showed absolute growth, but no significant changes in Z-scores. Sweat chloride concentration decreased by 52.8 mmol/L (<em>p</em> &lt; 0.001). Pulmonary exacerbations and antibiotic use significantly declined (<em>p</em> &lt; 0.001 for both). Despite limitations in spirometry data collection, FEV1 values showed a median increase of 6 percentage points. Oropharyngeal swab cultures for <em>Pseudomonas aeruginosa</em> positivity dropped from 43.6 % to 5.1 %. Safety assessments showed a transient rise in alkaline phosphatase (<em>p</em> = 0.011), but no significant hepatotoxicity. The most common adverse events were increased respiratory secretions (25.6 %) and abdominal pain (15.4 %). One temporary treatment suspension and one dose reduction occurred, but no patient required permanent discontinuation.</div></div><div><h3>Conclusions</h3><div>ETI demonstrated effectiveness in improving weight gain, reducing pulmonary exacerbations, and significantly lowering sweat chloride concentration. The treatment was well-tolerated, with a favorable safety profile. These findings align with existing literature, supporting ETI's role as a transformative therapy in pediatric CF management.</div></div>","PeriodicalId":14867,"journal":{"name":"Jornal de pediatria","volume":"101 5","pages":"Article 101420"},"PeriodicalIF":2.5,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144484465","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A response to \"Comparative efficacy of LifeVac® and Heimlich Maneuver in simulated airway obstruction\".","authors":"Simon Gould","doi":"10.1016/j.jped.2025.101427","DOIUrl":"10.1016/j.jped.2025.101427","url":null,"abstract":"","PeriodicalId":14867,"journal":{"name":"Jornal de pediatria","volume":" ","pages":"101427"},"PeriodicalIF":2.5,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12357135/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144816705","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Remimazolam for preventing sevoflurane-induced emergence delirium after pediatric laparoscopic inguinal hernia repair: a placebo-controlled randomized clinical trial","authors":"Yiwen Lu ,&nbsp;Guangbin Liang ,&nbsp;Yan Lu ,&nbsp;Jingjing Wang ,&nbsp;Jianhang Mo ,&nbsp;Zhiyuan Chen ,&nbsp;Ruizhao Shao ,&nbsp;Kui Hu ,&nbsp;Ping Pang ,&nbsp;Xiaoxia Gu","doi":"10.1016/j.jped.2025.101423","DOIUrl":"10.1016/j.jped.2025.101423","url":null,"abstract":"<div><h3>Objective</h3><div>To investigate the effectiveness and safety of remimazolam in preventing the emergence of delirium in children undergoing pediatric laparoscopic inguinal hernia surgery under combined intravenous and inhalation anesthesia.</div></div><div><h3>Methods</h3><div>A total of 184 pediatric patients aged 3–14 years who were undergoing laparoscopic inguinal hernia surgery were included. Patients were randomly assigned to receive either 0.1 mg/kg remimazolam (experimental group, <em>n</em> = 92) or 0.9 % normal saline (control group, <em>n</em> = 92) after the procedure. The primary outcome was the incidence of emergence delirium, which would manifest as a difference in the pediatric anesthesia emergence delirium (PAED) score between the two groups. The secondary outcomes included postoperative pain severity, duration of postanesthesia care unit (PACU) stay, sufentanil usage, parental satisfaction, mean arterial pressure (MAP), blood oxygen saturation (SpO₂), and heart rate (HR).</div></div><div><h3>Results</h3><div>The experimental group showed significantly lower overall PAED scores (mean difference = −2.28, 95 % CI:2.73 to −1.82; Cohen's <em>d</em> = 1.12, <em>p</em> &lt; 0.001) and emergence delirium incidence (7.61 % vs 41.30 %; risk difference = 33.69 %, 95 % CI 21.60 % to 45.10 %; relative risk = 0.18, 95 % CI 0.09–0.37; <em>p</em> &lt; 0.001). They also showed better hemodynamic stability (lower MAP/HR, higher SpO₂), reduced pain, shorter PACU stay, less sufentanil use, and higher parental satisfaction (all <em>p</em> &lt; 0.05).</div></div><div><h3>Conclusion</h3><div>Administration of 0.1 mg/kg remimazolam after pediatric laparoscopic inguinal hernia surgery could contribute to preventing the development of emergence delirium by smoothing hemodynamic changes and alleviating postoperative pain.</div></div>","PeriodicalId":14867,"journal":{"name":"Jornal de pediatria","volume":"101 5","pages":"Article 101423"},"PeriodicalIF":2.5,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144816708","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Obstructive sleep apnea syndrome in children with cerebral palsy in Brazil: a multicenter study","authors":"Bruno Leonardo Scofano Dias,&nbsp;Fernanda Marinho de Lima,&nbsp;Daniela Fava,&nbsp;Fernanda Jordão Pinto Marques,&nbsp;Frederico José de Carvalho Godinho,&nbsp;Alessandra Lemos de Carvalho,&nbsp;Sara Virgínia Paiva Santos,&nbsp;Fernanda de Lourdes da Cunha Pinto,&nbsp;Danielle Bruno Jardim,&nbsp;Wilerson Marques Bessa","doi":"10.1016/j.jped.2025.101432","DOIUrl":"10.1016/j.jped.2025.101432","url":null,"abstract":"<div><h3>Objectives</h3><div>To evaluate the prevalence of high risk for obstructive sleep apnea syndrome (HR-OSAS) in Brazilian children with cerebral palsy (CP) using the Pediatric Obstructive Sleep Apnea Screening Tool (PosaST) and to analyze its association with demographic, clinical and functional (Gross Motor Function Classification System [GMFCS]) variables.</div></div><div><h3>Methods</h3><div>Multicenter, cross-sectional, exploratory study.</div></div><div><h3>Results</h3><div>There were 312 children (median age 6.0 years, IQR 5.0–8.0) included. The prevalence of HR-OSAS in GMFCS I-V was 9.0 %. The prevalence of HR-OSAS in GMFCS V (14.7 %) was significantly higher compared to GMFCS I-IV (6.4 %) and to the frequency of OSAS in typically developing (TD) children assessed by polysomnography (5.8 %) according to literature data. Significantly higher frequencies of palatine tonsil hypertrophy, hospitalizations and outpatient antibiotic use for respiratory causes (last 12 months), gastroesophageal reflux disease, drooling and epilepsy were found in GMFCS V. Palatine tonsil hypertrophy was significantly associated with HR-OSAS. GMFCS V was significantly correlated with HR-OSAS at the expense of its significantly higher prevalence of palatine tonsil hypertrophy.</div></div><div><h3>Conclusions</h3><div>The prevalence of HR-OSAS in Brazilian children with CP (GMFCS V) was higher than the frequency of OSAS in TD children assessed by polysomnography. HR-OSAS was significantly more prevalent in GMFCS V compared with GMFCS I-IV. Palatine tonsil hypertrophy was significantly associated with HR-OSAS. GMFCS V was significantly correlated with HR-OSAS due to its significantly higher prevalence of palatine tonsil hypertrophy. PosaST may be a reliable questionnaire for Brazilian children with CP, but studies are needed to define the HR-OSAS cutoff score in this population.</div></div>","PeriodicalId":14867,"journal":{"name":"Jornal de pediatria","volume":"101 5","pages":"Article 101432"},"PeriodicalIF":2.5,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144821491","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The full blood count as a tool of differentiation between benign and malignant lymphadenopathy in pediatric and adolescent populations","authors":"Mariana Moreira Magnabosco da Silva ,&nbsp;Leniza Costa Lima Lichtvan ,&nbsp;Thaís Cugler Meneghetti","doi":"10.1016/j.jped.2025.05.001","DOIUrl":"10.1016/j.jped.2025.05.001","url":null,"abstract":"<div><h3>Objective</h3><div>Studies have shown the benefit of ratios between cell types in full blood count for the diagnosis and prognosis of various pathologies, but its use in the investigation of lymphadenopathy is still controversial. The aim of this study is to assess whether there is a difference between the full blood count ratios of children and adolescents with lymphadenopathy who had benign or malignant causes identified in excisional biopsies during the investigation of lymphadenopathy.</div></div><div><h3>Method</h3><div>This is a cross-sectional observational study. A total of 72 participants between 0 and 17 years old who underwent an excisional lymph node biopsy and had their full blood count collected up to 15 days before the procedure were included. The participants were divided into two groups, malignant and benign, according to the biopsy result. Neutrophils/lymphocytes (N/L), monocytes/lymphocytes (M/L), and platelets/lymphocytes (P/L) ratios were then calculated and compared between the groups.</div></div><div><h3>Results</h3><div>The mean full blood count ratios for the benign and malignant groups, respectively, were: N/L 2.36 × 3.28 <em>(p</em> <em>=</em> <em>0.09)</em>, M/L 0.30 × 0.32 <em>(p</em> <em>=</em> 0.722<em>)</em>, P/L 180.53 × 191.30 <em>(p</em> <em>=</em> <em>0.249)</em>.</div></div><div><h3>Conclusion</h3><div>The use of full blood count ratios as predictors of malignant or benign results has no proven statistical significance. Higher ratio values tend towards malignant results but should be interpreted with caution, as this is only one of the factors to be considered during the investigation.</div></div>","PeriodicalId":14867,"journal":{"name":"Jornal de pediatria","volume":"101 5","pages":"Article 101413"},"PeriodicalIF":2.5,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144187029","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Parents' perception of their children's neurodevelopment during the COVID-19 pandemic and associated factors","authors":"Sabrina Ribeiro Ibiapina ,&nbsp;Taís Michele Werle ,&nbsp;Milena Monticelli Giongo ,&nbsp;Magda Lahorgue Nunes","doi":"10.1016/j.jped.2025.06.002","DOIUrl":"10.1016/j.jped.2025.06.002","url":null,"abstract":"<div><h3>Objective</h3><div>To verify parents’/caregivers’ perceptions of changes in their children’s development during the COVID-19 pandemic and factors associated with such perceptions.</div></div><div><h3>Methods</h3><div>Cross-sectional study using an online survey made available to parents/caregivers of children between 0-7 years old, from September 2021 to March 2023 in two Brazilian states. Respondents answered questions about their perceptions regarding their children's neurodevelopment, and worsening of neurodevelopment during the COVID-19 pandemic. Validated questionnaires such as M-CHAT, “Swanson, Nolan and Pellham,” and “Strengths and Difficulties “were applied according to age. Comparisons were made using the chi-square test or Fisher's exact test, and Poisson regression was used in the univariate analysis and in the multivariate analysis.</div></div><div><h3>Results</h3><div>Data from 589 children were obtained, 49.7% aged 0-3 years and 50.3% 4-7 years. Of the 0-3 age group, 50 (17.1%) were perceived as having abnormal neurodevelopment, and 79 (27.0%) as having worsened neurodevelopment during the pandemic. Of the 4-7 year group, 76 (25.7%) were perceived as having abnormal neurodevelopment, and 104 (35.1%) as having worsened their neurodevelopment. Significant risk factors associated with the perception of abnormal neurodevelopment were maternal schooling, the child's sex and age; for the perception of worsening neurodevelopment were the child's sex and age, low socioeconomic status, degree of social isolation, and death in the family due to COVID-19.</div></div><div><h3>Conclusion</h3><div>Data from the present study showed that parents/ caregivers' perception of normal neurodevelopment was significantly higher than their recognition of abnormalities. In addition, a significant percentage perceived a worsening during the COVID-19 pandemic.</div></div>","PeriodicalId":14867,"journal":{"name":"Jornal de pediatria","volume":"101 5","pages":"Article 101422"},"PeriodicalIF":2.5,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144637071","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Empower your child's health: tailored strategies to prevent rhinosinusitis","authors":"Francesca De Bernardi ,&nbsp;Chiara Zeroli ,&nbsp;Sandra Coecke ,&nbsp;Massimo Landi ,&nbsp;Stefania Gallo ,&nbsp;Paolo Castelnuovo ,&nbsp;Luana Nosetti","doi":"10.1016/j.jped.2024.02.005","DOIUrl":"10.1016/j.jped.2024.02.005","url":null,"abstract":"<div><h3>Objective</h3><div>This review explores preventive strategies for pediatric rhinosinusitis and examines their potential impact on children's mental well-being, advocating for a comprehensive holistic approach that includes medical disciplines and government policies to support EU and global prevention strategies.</div></div><div><h3>Sources</h3><div>A comprehensive search encompassed Medline, Embase, PubMed, and the Cochrane Library for English-language articles from January 2010 to December 2023. Inclusion criteria involved papers on pediatric rhinosinusitis prevention in the pediatric population, published in peer-reviewed journals. Following the removal of duplicates and exclusion of irrelevant studies, 20 unique titles were included in the review.</div></div><div><h3>Summary of the findings</h3><div>The review underscores the challenges posed by the similarity of symptoms between pediatric rhinosinusitis and other common childhood illnesses. It emphasizes the interconnected nature of upper and lower airways, illustrating the potential impact on both physical and mental well-being in children. The findings highlight the necessity for a multifaceted prevention approach, supported by individualized prevention plans, medical professional involvement, and government policies.</div></div><div><h3>Conclusions</h3><div>The holistic research and clinical approach proposed in this review contribute valuable insights into the global efforts aimed at reducing the incidence of pediatric rhinosinusitis while promoting the mental well-being of children. The article serves as an informative resource for readers seeking a deeper understanding of pediatric rhinosinusitis prevention strategies.</div><div>The review emphasizes the necessity of a multidisciplinary approach, involving pediatricians, otolaryngologists, pneumologists, and allergologists, in PRS prevention. Government prioritization of preventive measures is essential. Precision medicine and integrative approaches are recommended for tailored treatment plans.</div></div>","PeriodicalId":14867,"journal":{"name":"Jornal de pediatria","volume":"101 5","pages":"Article 101417"},"PeriodicalIF":2.5,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144258098","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}